메뉴 건너뛰기




Volumn 23, Issue 5, 1999, Pages 323-334

p53 does not control the spindle assembly cell cycle checkpoint but mediates G1 arrest in response to disruption of microtubule system

Author keywords

Cell cycle checkpoints; Microtubules; p53

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; DEMECOLCINE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P53;

EID: 0032696428     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1006/cbir.1999.0362     Document Type: Article
Times cited : (29)

References (61)
  • 2
    • 0028980494 scopus 로고
    • P53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts
    • Agarwal ML, Agarwal A, Taylor WR, Stark GR. p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts. Proc Natl Acad Sci U S A. 92:1995;8493-8497.
    • (1995) Proc Natl Acad Sci U S a , vol.92 , pp. 8493-8497
    • Agarwal, M.L.1    Agarwal, A.2    Taylor, W.R.3    Stark, G.R.4
  • 5
    • 0030988817 scopus 로고    scopus 로고
    • The p53 activation and apoptosis induced by DNA damage are reversibly inhibited by salicylate
    • Chernov MV, Stark GR. The p53 activation and apoptosis induced by DNA damage are reversibly inhibited by salicylate. Oncogene. 14:1997;2503-2510.
    • (1997) Oncogene , vol.14 , pp. 2503-2510
    • Chernov, M.V.1    Stark, G.R.2
  • 7
    • 0029315510 scopus 로고
    • Tumour suppressors, kinases and clamps: How p53 regulates the cell cycle in response to DNA damage
    • Cox LS, Lane DP. Tumour suppressors, kinases and clamps: how p53 regulates the cell cycle in response to DNA damage. Bioessays. 17:1995;501-508.
    • (1995) Bioessays , vol.17 , pp. 501-508
    • Cox, L.S.1    Lane, D.P.2
  • 9
    • 0030929838 scopus 로고    scopus 로고
    • DNA rereplication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRb function
    • Di Leonardo A, Khan SH, Linke SP, Greco V, Seidita G, Wahl GM. DNA rereplication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRb function. Cancer Res. 57:1997;1013-1019.
    • (1997) Cancer Res , vol.57 , pp. 1013-1019
    • Di Leonardo, A.1    Khan, S.H.2    Linke, S.P.3    Greco, V.4    Seidita, G.5    Wahl, G.M.6
  • 10
    • 0028220204 scopus 로고
    • P53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
    • Dulic V, Kaufmann WK, Wilson SJ, Tlsty TD, Lees E, Harper JW, Elledge SJ, Reed SI. p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell. 76:1994;1013-1023.
    • (1994) Cell , vol.76 , pp. 1013-1023
    • Dulic, V.1    Kaufmann, W.K.2    Wilson, S.J.3    Tlsty, T.D.4    Lees, E.5    Harper, J.W.6    Elledge, S.J.7    Reed, S.I.8
  • 13
    • 0027500246 scopus 로고
    • Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents
    • Fritsche M, Haessler C, Brandner G. Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents. Oncogene. 8:1993;307-318.
    • (1993) Oncogene , vol.8 , pp. 307-318
    • Fritsche, M.1    Haessler, C.2    Brandner, G.3
  • 14
    • 0032574788 scopus 로고    scopus 로고
    • An oncogenic form p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control
    • Gualberto A, Kenneth A, Kozariewicz K, Tlsty TD. An oncogenic form p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control. Proc Natl Acad Sci U S A. 95:1998;5166-5171.
    • (1998) Proc Natl Acad Sci U S a , vol.95 , pp. 5166-5171
    • Gualberto, A.1    Kenneth, A.2    Kozariewicz, K.3    Tlsty, T.D.4
  • 15
    • 0028568315 scopus 로고
    • Cell cycle control and cancer
    • Hartwell LH, Kastan MB. Cell cycle control and cancer. Science. 266:1994;1821-1828.
    • (1994) Science , vol.266 , pp. 1821-1828
    • Hartwell, L.H.1    Kastan, M.B.2
  • 16
    • 0026303190 scopus 로고
    • P53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts
    • Harvey DM, Levine AJ. p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts. Genes Dev. 5:1991;2375-2385.
    • (1991) Genes Dev , vol.5 , pp. 2375-2385
    • Harvey, D.M.1    Levine, A.J.2
  • 17
    • 0028908796 scopus 로고
    • Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression
    • Horikoshi N, Usheva A, Chen J, Levine AJ, Weinmann R, Shenk T. Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression. Mol Cell Biol. 15:1995;227-234.
    • (1995) Mol Cell Biol , vol.15 , pp. 227-234
    • Horikoshi, N.1    Usheva, A.2    Chen, J.3    Levine, A.J.4    Weinmann, R.5    Shenk, T.6
  • 18
    • 0030693181 scopus 로고    scopus 로고
    • JNK1, JNK2 and JNK3 are p53 N-terminal serine 34 kinases
    • Hu MC, Qiu WR, Wang YP. JNK1, JNK2 and JNK3 are p53 N-terminal serine 34 kinases. Oncogene. 15:1997;2277-2287.
    • (1997) Oncogene , vol.15 , pp. 2277-2287
    • Hu, M.C.1    Qiu, W.R.2    Wang, Y.P.3
  • 19
  • 20
    • 0029973389 scopus 로고    scopus 로고
    • Cell-cycle control and its watchman
    • Jacks T, Weinberg RA. Cell-cycle control and its watchman. Nature. 381:1996;643-644.
    • (1996) Nature , vol.381 , pp. 643-644
    • Jacks, T.1    Weinberg, R.A.2
  • 21
    • 0029004353 scopus 로고
    • Raf phosphorylates p53 in vitro and potentiates p53-dependent transcriptional transactivation in vivo
    • Jamal S, Ziff EB. Raf phosphorylates p53 in vitro and potentiates p53-dependent transcriptional transactivation in vivo. Oncogene. 10:1995;2095-2101.
    • (1995) Oncogene , vol.10 , pp. 2095-2101
    • Jamal, S.1    Ziff, E.B.2
  • 22
    • 0026643589 scopus 로고
    • Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitotis
    • Jordan MA, Thrower D, Wilson L. Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitotis. J Cell Sci. 102:1992;401-416.
    • (1992) J Cell Sci , vol.102 , pp. 401-416
    • Jordan, M.A.1    Thrower, D.2    Wilson, L.3
  • 24
    • 0032005132 scopus 로고    scopus 로고
    • P53 and pRb prevent rereplication in response to microtubule inhibitors by mediating a reversible G1 arrest
    • Khan SH, Wahl GM. p53 and pRb prevent rereplication in response to microtubule inhibitors by mediating a reversible G1 arrest. Cancer Res. 58:1998;396-401.
    • (1998) Cancer Res , vol.58 , pp. 396-401
    • Khan, S.H.1    Wahl, G.M.2
  • 25
    • 0029972806 scopus 로고    scopus 로고
    • P53: Puzzle and paradigm
    • Ko LJ, Prives C. p53: puzzle and paradigm. Genes Dev. 10:1996;1054-1072.
    • (1996) Genes Dev , vol.10 , pp. 1054-1072
    • Ko, L.J.1    Prives, C.2
  • 26
    • 0025979335 scopus 로고
    • Raf-1 protein kinase is required for growth of induced NIH/3T3 cells
    • Kolch W, Heidecker G, Lloyd P, Rapp UR. Raf-1 protein kinase is required for growth of induced NIH/3T3 cells. Nature. 349:1991;426-438.
    • (1991) Nature , vol.349 , pp. 426-438
    • Kolch, W.1    Heidecker, G.2    Lloyd, P.3    Rapp, U.R.4
  • 28
    • 0031931414 scopus 로고    scopus 로고
    • Characterization of the p53-dependent postmitotic checkpoint following spindle disruption
    • Lanni JS, Jacks T. Characterization of the p53-dependent postmitotic checkpoint following spindle disruption. Mol Cell Biol. 18:1998;1055-1064.
    • (1998) Mol Cell Biol , vol.18 , pp. 1055-1064
    • Lanni, J.S.1    Jacks, T.2
  • 29
    • 0026687883 scopus 로고
    • Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53
    • Lees Miller SP, Sakaguchi K, Ullrich SJ, Appella E, Anderson CW. Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53. Mol Cell Biol. 12:1992;5041-5049.
    • (1992) Mol Cell Biol , vol.12 , pp. 5041-5049
    • Lees Miller, S.P.1    Sakaguchi, K.2    Ullrich, S.J.3    Appella, E.4    Anderson, C.W.5
  • 30
    • 0030941458 scopus 로고    scopus 로고
    • P53, the cellular gatekeeper for growth and division
    • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell. 88:1997;323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 31
    • 0032190629 scopus 로고    scopus 로고
    • Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
    • Lin AW, Barradas M, Stone JC, Van Aelst L, Serrano M, Lowe SW. Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes Dev. 12:1998;3008-3019.
    • (1998) Genes Dev , vol.12 , pp. 3008-3019
    • Lin, A.W.1    Barradas, M.2    Stone, J.C.3    Van Aelst, L.4    Serrano, M.5    Lowe, S.W.6
  • 32
    • 0028455516 scopus 로고
    • Post-translational modification of p53
    • Meek DW. Post-translational modification of p53. Semin Cancer Biol. 5:1994;203-210.
    • (1994) Semin Cancer Biol , vol.5 , pp. 203-210
    • Meek, D.W.1
  • 34
    • 0025111068 scopus 로고
    • Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53
    • Michalovitz D, Halevy O, Oren M. Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53. Cell. 62:1990;671-680.
    • (1990) Cell , vol.62 , pp. 671-680
    • Michalovitz, D.1    Halevy, O.2    Oren, M.3
  • 35
    • 0026663552 scopus 로고
    • Phosphorylation of the p53 tumour-suppressor protein at three N-terminal sites by a novel casein kinase I-like enzyme
    • Milne DM, Palmer RH, Campbell DG, Meek DW. Phosphorylation of the p53 tumour-suppressor protein at three N-terminal sites by a novel casein kinase I-like enzyme. Oncogene. 7:1992;1361-1369.
    • (1992) Oncogene , vol.7 , pp. 1361-1369
    • Milne, D.M.1    Palmer, R.H.2    Campbell, D.G.3    Meek, D.W.4
  • 36
    • 0028363749 scopus 로고
    • Phosphorylation of the tumor suppressor protein p53 by mitogen-activated protein kinases
    • Milne DM, Campbell DG, Caudwell FB, Meek DW. Phosphorylation of the tumor suppressor protein p53 by mitogen-activated protein kinases. J Biol Chem. 269:1994;9253-9260.
    • (1994) J Biol Chem , vol.269 , pp. 9253-9260
    • Milne, D.M.1    Campbell, D.G.2    Caudwell, F.B.3    Meek, D.W.4
  • 37
    • 0028966941 scopus 로고
    • P53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1
    • Milne DM, Campbell LE, Campbell DG, Meek DW. p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1. J Biol Chem. 270:1995;5511-5518.
    • (1995) J Biol Chem , vol.270 , pp. 5511-5518
    • Milne, D.M.1    Campbell, L.E.2    Campbell, D.G.3    Meek, D.W.4
  • 38
    • 0029658664 scopus 로고    scopus 로고
    • Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage
    • Minn A-J, Boise L-H, Thompson C-B. Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage. Genes Dev. 10:1996;2621-2631.
    • (1996) Genes Dev , vol.10 , pp. 2621-2631
    • Minn, A.-J.1    Boise, L.-H.2    Thompson, C.-B.3
  • 40
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita T, Reed JC. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell. 80:1995;293-299.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 42
    • 0028109125 scopus 로고
    • Transactivation of the human multidrug resistance (MDR1) gene promoter by p53 mutants
    • Nguyen KT, Liu B, Ueda K, Gottesman MM, Pastan I, Chin KV. Transactivation of the human multidrug resistance (MDR1) gene promoter by p53 mutants. Oncol Res. 6:1994;71-77.
    • (1994) Oncol Res , vol.6 , pp. 71-77
    • Nguyen, K.T.1    Liu, B.2    Ueda, K.3    Gottesman, M.M.4    Pastan, I.5    Chin, K.V.6
  • 43
    • 0032546163 scopus 로고    scopus 로고
    • A checkpoint on the road to cancer
    • Orr-Weaver TL, Weinberg RA. A checkpoint on the road to cancer. Nature. 392:1998;223-224.
    • (1998) Nature , vol.392 , pp. 223-224
    • Orr-Weaver, T.L.1    Weinberg, R.A.2
  • 46
    • 0027158460 scopus 로고
    • Wild-type but not mutant p53 can repress transcription initiation in vitro by interfering with the binding of basal transcription factors to the TATA motif
    • Ragimov N, Krauskopf A, Navot N, Rotter V, Oren M, Aloni Y. Wild-type but not mutant p53 can repress transcription initiation in vitro by interfering with the binding of basal transcription factors to the TATA motif. Oncogene. 8:1993;1183-1193.
    • (1993) Oncogene , vol.8 , pp. 1183-1193
    • Ragimov, N.1    Krauskopf, A.2    Navot, N.3    Rotter, V.4    Oren, M.5    Aloni, Y.6
  • 47
    • 0027942033 scopus 로고
    • Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle
    • Rieder CL, Schultz A, Cole R, Sluder G. Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle. J Cell Biol. 127:1994;1301-1310.
    • (1994) J Cell Biol , vol.127 , pp. 1301-1310
    • Rieder, C.L.1    Schultz, A.2    Cole, R.3    Sluder, G.4
  • 48
    • 0029160299 scopus 로고
    • The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores
    • Rieder CL, Cole RW, Khodjakov A, Sluder G. The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores. J Cell Biol. 130:1995;941-948.
    • (1995) J Cell Biol , vol.130 , pp. 941-948
    • Rieder, C.L.1    Cole, R.W.2    Khodjakov, A.3    Sluder, G.4
  • 50
    • 0031979686 scopus 로고    scopus 로고
    • Activation of p53-mediated cell cycle checkpoint in response to micronuclei formation
    • Sablina A, Ilyinskaya G, Rubtsova S, Agapova L, Chumakov P, Kopnin B. Activation of p53-mediated cell cycle checkpoint in response to micronuclei formation. J Cell Sci. 111:1998;977-984.
    • (1998) J Cell Sci , vol.111 , pp. 977-984
    • Sablina, A.1    Ilyinskaya, G.2    Rubtsova, S.3    Agapova, L.4    Chumakov, P.5    Kopnin, B.6
  • 51
    • 0032191393 scopus 로고    scopus 로고
    • Tumor surveillance via the ARF-p53 pathway
    • Sherr CJ. Tumor surveillance via the ARF-p53 pathway. Genes Dev. 12:1998;2984-2991.
    • (1998) Genes Dev , vol.12 , pp. 2984-2991
    • Sherr, C.J.1
  • 54
    • 0028813528 scopus 로고
    • Evidence for a second cell cycle block at G2/M by p53
    • Stewart N, Hicks GG, Paraskevas F, Mowat M. Evidence for a second cell cycle block at G2/M by p53. Oncogene. 10:1995;109-115.
    • (1995) Oncogene , vol.10 , pp. 109-115
    • Stewart, N.1    Hicks, G.G.2    Paraskevas, F.3    Mowat, M.4
  • 55
    • 0032505111 scopus 로고    scopus 로고
    • Expression of the antiapoptotic MCL1 gene product is regulated by a mitogen activated protein kinase-mediated pathway triggered through microtubule disruption and protein kinase C
    • Townsend KJ, Trusty JL, Traupman MA, Eastman A, Craig RW. Expression of the antiapoptotic MCL1 gene product is regulated by a mitogen activated protein kinase-mediated pathway triggered through microtubule disruption and protein kinase C. Oncogene. 17:1998;1223-1234.
    • (1998) Oncogene , vol.17 , pp. 1223-1234
    • Townsend, K.J.1    Trusty, J.L.2    Traupman, M.A.3    Eastman, A.4    Craig, R.W.5
  • 57
    • 0021910637 scopus 로고
    • A colon cancer cell line (LIM1215) derived from a patient with inherited nonpolyposis colorectal cancer
    • Whitehead RH, Macrae FA, St John DJ, Ma J. A colon cancer cell line (LIM1215) derived from a patient with inherited nonpolyposis colorectal cancer. J Natl Cancer Inst. 74:1985;759-765.
    • (1985) J Natl Cancer Inst , vol.74 , pp. 759-765
    • Whitehead, R.H.1    MacRae, F.A.2    St John, D.J.3    Ma, J.4
  • 59
    • 0027191153 scopus 로고
    • The core promoter region of the P-glycoprotein gene is sufficient to confer differential responsiveness to wild-type and mutant p53
    • Zastawny RL, Salvino R, Chen J, Benchimol S, Ling V. The core promoter region of the P-glycoprotein gene is sufficient to confer differential responsiveness to wild-type and mutant p53. Oncogene. 8:1993;1529-1535.
    • (1993) Oncogene , vol.8 , pp. 1529-1535
    • Zastawny, R.L.1    Salvino, R.2    Chen, J.3    Benchimol, S.4    Ling, V.5
  • 61
    • 0028016179 scopus 로고
    • Hyperphosphorylation of p53 induced by okadaic acid attenuates its transcriptional activation function
    • Zhang W, McClain C, Gau JP, Guo XY, Deisseroth AB. Hyperphosphorylation of p53 induced by okadaic acid attenuates its transcriptional activation function. Cancer Res. 54:1994;4448-4453.
    • (1994) Cancer Res , vol.54 , pp. 4448-4453
    • Zhang, W.1    McClain, C.2    Gau, J.P.3    Guo, X.Y.4    Deisseroth, A.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.