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Volumn 1, Issue 1, 2000, Pages 73-94

Genetic variation in coronary heart disease and myocardial infarction: Methodological overview and clinical evidence

Author keywords

Cardiovascular; Coronary artery disease; Genome; Haplotype; Linkage analysis; Myocardial infarction; Polymorphism

Indexed keywords

CORONARY ARTERY DISEASE; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENETICS; HEART INFARCTION; HUMAN; METABOLISM; PATHOPHYSIOLOGY; REVIEW;

EID: 0034139722     PISSN: 14622416     EISSN: None     Source Type: Journal    
DOI: 10.1517/14622416.1.1.73     Document Type: Review
Times cited : (58)

References (99)
  • 2
    • 0028298802 scopus 로고
    • Myocardial infarction and coronary deaths in the World Health Organization MONICA Project - Registration procedures, event rates, and case-fatality rates in 38 populations from 21 countries in four continents
    • TUNSTALL-PEDOE H, KUULASMAA K, AMOUYEL P, ARWEILER D, RAJAKANGAS A-M, PAJAK A (FOR THE WHO MONICA PROJECT): Myocardial infarction and coronary deaths in the World Health Organization MONICA Project - registration procedures, event rates, and case-fatality rates in 38 populations from 21 countries in four continents. Circulation (1994) 90:583-612.
    • (1994) Circulation , vol.90 , pp. 583-612
    • Tunstall-Pedoe, H.1    Kuulasmaa, K.2    Amouyel, P.3    Arweiler, D.4    Rajakangas, A.-M.5    Pajak, A.6
  • 3
    • 85037457232 scopus 로고    scopus 로고
    • AMERICAN HEART ASSOCIATION HEART AND STROKE FACTS: American Heart Association, Dallas, USA
    • http://www.amheart.org/heart_and_stroke_A-Z_guide AMERICAN HEART ASSOCIATION HEART AND STROKE FACTS: American Heart Association, Dallas, USA (1999).
    • (1999)
  • 4
    • 0345536531 scopus 로고
    • The increased risk of death from ischemic heart disease in first degree relatives of 121 men and 96 women with ischemic heart disease
    • SLACK J, EVANS KA: The increased risk of death from ischemic heart disease in first degree relatives of 121 men and 96 women with ischemic heart disease. J. Med. Genet. (1966) 3:239-257.
    • (1966) J. Med. Genet. , vol.3 , pp. 239-257
    • Slack, J.1    Evans, K.A.2
  • 6
    • 0019984152 scopus 로고
    • Factors affecting the extent and severity of coronary artery disease in patients enrolled in the coronary artery bypass surgery study
    • VLIETSTRA RE, KRONMAL RA, FRYE RL, SETH AK, TRISTANI FE, KILLIP III T: Factors affecting the extent and severity of coronary artery disease in patients enrolled in the coronary artery bypass surgery study. Arteriosclerosis (1982) 2:208-215.
    • (1982) Arteriosclerosis , vol.2 , pp. 208-215
    • Vlietstra, R.E.1    Kronmal, R.A.2    Frye, R.L.3    Seth, A.K.4    Tristani, F.E.5    Killip III, T.6
  • 7
    • 0033543116 scopus 로고    scopus 로고
    • Age-dependent association of apolipoprotein E genotype with coronary and aortic atherosclerosis in middle-aged men - An autopsy study
    • ILVESKOSKI E, PEROLA M, LEHTIMÄKI T et al.: Age-dependent association of apolipoprotein E genotype with coronary and aortic atherosclerosis in middle-aged men - an autopsy study. Circulation (1999) 100:608-613.
    • (1999) Circulation , vol.100 , pp. 608-613
    • Ilveskoski, E.1    Perola, M.2    Lehtimäki, T.3
  • 8
    • 0031471855 scopus 로고    scopus 로고
    • A genome based resource of molecular cardiovascular medicine
    • HWANG DM: A genome based resource of molecular cardiovascular medicine. Circulation (1997) 96:4146-4203. Complete overview on genes involved in cardiovascular disease and a resource for internet access of genome data.
    • (1997) Circulation , vol.96 , pp. 4146-4203
    • Hwang, D.M.1
  • 9
    • 0032524383 scopus 로고    scopus 로고
    • Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome
    • WANG DG, FAN JB, SIAO CJ et al.: Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. Science (1998) 280:1077-1082. Excellent report on genes associated with cardiovascular disease and on genetic variation.
    • (1998) Science , vol.280 , pp. 1077-1082
    • Wang, D.G.1    Fan, J.B.2    Siao, C.J.3
  • 10
    • 0033358728 scopus 로고    scopus 로고
    • Sequence diversity in 36 candidate genes for cardiovascular disorders
    • CAMBIEN F, POIRIER O, NICAUD V et al.: Sequence diversity in 36 candidate genes for cardiovascular disorders. Am. J. Hum. Genet. (1999) 65:183-191. Major contribution with systematic screening of genetic diversity in 36 candidate genes for cardiovascular disease.
    • (1999) Am. J. Hum. Genet. , vol.65 , pp. 183-191
    • Cambien, F.1    Poirier, O.2    Nicaud, V.3
  • 11
    • 0032991552 scopus 로고    scopus 로고
    • Characterization of single-nucleotide polymorphisms in coding regions of human genes
    • CARGILL M, ALTSCHULER D, IRELAND J et al.: Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nature Genet. (1999) 22:231-238. This systematic screening for polymorphisms in the coding region of 114 genes relevant to cardiovascular disease, endocrinology and neuropsychiatry provides a fundamental description of sequence variation in human genes.
    • (1999) Nature Genet. , vol.22 , pp. 231-238
    • Cargill, M.1    Altschuler, D.2    Ireland, J.3
  • 12
    • 0032990407 scopus 로고    scopus 로고
    • Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis
    • HALUSHKA MK, FAN J-B, BENTLEY K et al.: Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis. Nature Genet. (1999) 22:239-247. Excellent systematic search of single-nucleotide polymorphisms in 75 candidate genes for blood pressure homeostasis and hypertension which provides a fundamental description on human allelic variation and the frequency of protein-altering polymorphisms.
    • (1999) Nature Genet. , vol.22 , pp. 239-247
    • Halushka, M.K.1    Fan, J.-B.2    Bentley, K.3
  • 13
    • 0027377799 scopus 로고
    • Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
    • SPIELMAN RS, MCGINNIS RE, EWENS WJ: Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am. J. Hum. Genet. (1993) 52:506-513.
    • (1993) Am. J. Hum. Genet. , vol.52 , pp. 506-513
    • Spielman, R.S.1    Mcginnis, R.E.2    Ewens, W.J.3
  • 14
    • 0031912715 scopus 로고    scopus 로고
    • A sibship test for linkage in the presence of association: The sib transmission/disequilibrium test
    • SPIELMAN RS, EWENS WJ: A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test. Am. J. Hum. Genet. (1998) 62:450-458.
    • (1998) Am. J. Hum. Genet. , vol.62 , pp. 450-458
    • Spielman, R.S.1    Ewens, W.J.2
  • 15
    • 0033009208 scopus 로고    scopus 로고
    • Lack of association between genetic variations of apo A-I-C-III-A-IV gene cluster and myocardial infarction in a sample of European male: ECTIM study
    • KEE F, AMOUYEL P, FUMERON F: Lack of association between genetic variations of apo A-I-C-III-A-IV gene cluster and myocardial infarction in a sample of European male: ECTIM study. Atherosclerosis (1999) 145:187-195.
    • (1999) Atherosclerosis , vol.145 , pp. 187-195
    • Kee, F.1    Amouyel, P.2    Fumeron, F.3
  • 16
    • 0022899587 scopus 로고
    • Apolipoprotein B-gene DNA polymorphisms associated with myocardial infarction
    • HEGELE RA, HUANG L-S, HERBERT PN et al:. Apolipoprotein B-gene DNA polymorphisms associated with myocardial infarction. New Engl. J. Med. (1986) 315:1509-1515.
    • (1986) New Engl. J. Med. , vol.315 , pp. 1509-1515
    • Hegele, R.A.1    Huang, L.-S.2    Herbert, P.N.3
  • 17
    • 0029114443 scopus 로고
    • DNA polymorphisms of the apolipoprotein B gene are associated with altered plasma lipoprotein concentrations but not with perceived risk of cardiovascular disease: European Atherosclerosis Research Study
    • TURNER PR, TALMUD PJ, VISVIKIS S, EHNHOLM C, TIRET L: DNA polymorphisms of the apolipoprotein B gene are associated with altered plasma lipoprotein concentrations but not with perceived risk of cardiovascular disease: European Atherosclerosis Research Study. Atherosclerosis (1995) 116:221-234.
    • (1995) Atherosclerosis , vol.116 , pp. 221-234
    • Turner, P.R.1    Talmud, P.J.2    Visvikis, S.3    Ehnholm, C.4    Tiret, L.5
  • 18
    • 0028107588 scopus 로고
    • Apolipoprotein polymorphisms fail to define risk of coronary artery disease - Results of a prospective, angiographically controlled study
    • MARSHALL HW, MORRISON LC, WU LL et al.: Apolipoprotein polymorphisms fail to define risk of coronary artery disease - results of a prospective, angiographically controlled study. Circulation (1994) 89:567-577.
    • (1994) Circulation , vol.89 , pp. 567-577
    • Marshall, H.W.1    Morrison, L.C.2    Wu, L.L.3
  • 19
    • 0023860891 scopus 로고
    • Apolipoprotein E polymorphism and atherosclerosis
    • DAVIGNON J, GREGG RE, SING CF: Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis (1988) 8:1-21. Authoritative and comprehensive review of the apo E polymorphism and atherosclerosis.
    • (1988) Arteriosclerosis , vol.8 , pp. 1-21
    • Davignon, J.1    Gregg, R.E.2    Sing, C.F.3
  • 21
    • 0022918434 scopus 로고
    • Association of apolipoprotein E polymorphism, low density lipoprotein cholesterol, and coronary artery disease
    • LENZEN HJ, ASSMANN G, BUCHWALSKY R, SCHULTE H: Association of apolipoprotein E polymorphism, low density lipoprotein cholesterol, and coronary artery disease. Clin. Chem. (1986) 32:778-781.
    • (1986) Clin. Chem. , vol.32 , pp. 778-781
    • Lenzen, H.J.1    Assmann, G.2    Buchwalsky, R.3    Schulte, H.4
  • 22
    • 84942951233 scopus 로고
    • Apolipoprotein E alleles, dyslipidemia, and coronary heart disease - The Framingham Offspring Study
    • WILSON PWF, MYERS RH, LARSON MG, ORDOVAS JM, WOLF PA, SCHAEFER EJ: Apolipoprotein E alleles, dyslipidemia, and coronary heart disease - the Framingham Offspring Study. JAMA (1994) 272:1666-1671.
    • (1994) JAMA , vol.272 , pp. 1666-1671
    • Wilson, P.W.F.1    Myers, R.H.2    Larson, M.G.3    Ordovas, J.M.4    Wolf, P.A.5    Schaefer, E.J.6
  • 23
    • 0031470430 scopus 로고    scopus 로고
    • Common variation in the lipoprotein lipase gene: Effects on plasma lipids and risk of atherosclerosis
    • FISHER RM, HUMPHRIES SEA, TALMUD PJ: Common variation in the lipoprotein lipase gene: effects on plasma lipids and risk of atherosclerosis. Atherosclerosis (1997) 135:145-159.
    • (1997) Atherosclerosis , vol.135 , pp. 145-159
    • Fisher, R.M.1    Humphries, S.E.A.2    Talmud, P.J.3
  • 24
    • 0030752544 scopus 로고    scopus 로고
    • Lipoprotein lipase variants D9N and N291S are associated with increased plasma triglyceride and lower high-density lipoprotein cholesterol concentrations - Studies in the fasting and postprandial states: The European Atherosclerosis Research Studies
    • GERDES C, FISHER RM, NICAUD V et al. (ON BEHALF OF THE EARS GROUP): Lipoprotein lipase variants D9N and N291S are associated with increased plasma triglyceride and lower high-density lipoprotein cholesterol concentrations - studies in the fasting and postprandial states: The European Atherosclerosis Research Studies. Circulation (1997) 96:733-740.
    • (1997) Circulation , vol.96 , pp. 733-740
    • Gerdes, C.1    Fisher, R.M.2    Nicaud, V.3
  • 26
    • 0030167989 scopus 로고    scopus 로고
    • Identification of putative beneficial mutations for lipid transport
    • GALTON DJ, MATTU R, NEEDHAM EWA, CAVANNA J: Identification of putative beneficial mutations for lipid transport. J. Gastroenterol. (1996) 34(Suppl. 3):56-58.
    • (1996) J. Gastroenterol. , vol.34 , Issue.3 SUPPL. , pp. 56-58
    • Galton, D.J.1    Mattu, R.2    Needham, E.W.A.3    Cavanna, J.4
  • 27
    • 0033536024 scopus 로고    scopus 로고
    • Lipoprotein lipase mutations, plasma lipids and lipoproteins, and risk of ischemic heart disease
    • WITTRUP HH, TYBJAERG-HANSEN A, NORDESTGAARD BG: Lipoprotein lipase mutations, plasma lipids and lipoproteins, and risk of ischemic heart disease. Circulation (1999) 99:2901-2907.
    • (1999) Circulation , vol.99 , pp. 2901-2907
    • Wittrup, H.H.1    Tybjaerg-Hansen, A.2    Nordestgaard, B.G.3
  • 28
    • 0032231888 scopus 로고    scopus 로고
    • Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase
    • CLARK AG, WEISS KM, NICKERSON DA et al.: Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase. Am. J. Hum. Genet. (1998) 63:595-612. Important and fundamental report on the genetic diversity among different populations exemplified by full-scale detection of the allelic variation in the lipoprotein lipase gene.
    • (1998) Am. J. Hum. Genet. , vol.63 , pp. 595-612
    • Clark, A.G.1    Weiss, K.M.2    Nickerson, D.A.3
  • 29
    • 0031442667 scopus 로고    scopus 로고
    • Common C-to-T substitution at position -480 of the hepatic lipase promoter associated with a lowered lipase activity in coronary artery disease patients
    • JANSEN H, VERHOEVEN AJM, WEEKS L et al.: Common C-to-T substitution at position -480 of the hepatic lipase promoter associated with a lowered lipase activity in coronary artery disease patients. Arterioscler. Thromb. Vasc. Biol. (1997) 17:2837-2842.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 2837-2842
    • Jansen, H.1    Verhoeven, A.J.M.2    Weeks, L.3
  • 30
    • 0030203249 scopus 로고    scopus 로고
    • Allelic variation in the gene encoding the cholesteryl ester transfer protein is associated with variation in the plasma concentration of cholesteryl ester transfer protein
    • MCPHERSON R, GRUNDY SM, GUERRA R, COHEN JC: Allelic variation in the gene encoding the cholesteryl ester transfer protein is associated with variation in the plasma concentration of cholesteryl ester transfer protein. J. Lipid Res. (1996) 37:1743-1748.
    • (1996) J. Lipid Res. , vol.37 , pp. 1743-1748
    • Mcpherson, R.1    Grundy, S.M.2    Guerra, R.3    Cohen, J.C.4
  • 31
    • 0030934834 scopus 로고    scopus 로고
    • Heterogeneity at the CETP gene locus - Influence on plasma CETP concentrations and HDL cholesterol levels
    • KUIVENHOVEN JA, DEKNIJFF P, BOER JMA et al.: Heterogeneity at the CETP gene locus - influence on plasma CETP concentrations and HDL cholesterol levels. Arterioscler. Thromb. Vasc. Biol. (1997) 17:560-568.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 560-568
    • Kuivenhoven, J.A.1    Deknijff, P.2    Boer, J.M.A.3
  • 32
    • 0032495541 scopus 로고    scopus 로고
    • The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis
    • KUIVENHOVEN JA, JUKEMA JW, ZWINDERMAN AH et al. (FOR THE REGRESSION GROWTH EVALUATION STATIN STUDY GROUP): The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis. New Engl. J. Med. (1998) 338:86-93.
    • (1998) New Engl. J. Med. , vol.338 , pp. 86-93
    • Kuivenhoven, J.A.1    Jukema, J.W.2    Zwinderman, A.H.3
  • 34
    • 0029875770 scopus 로고    scopus 로고
    • A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis
    • WEISS EJ, BRAY PF, TAYBACK M et al.: A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis. New Engl. J. Med. (1996) 334:1090-1094.
    • (1996) New Engl. J. Med. , vol.334 , pp. 1090-1094
    • Weiss, E.J.1    Bray, P.F.2    Tayback, M.3
  • 35
    • 0033135674 scopus 로고    scopus 로고
    • b) positive platelets in patients with cardiovascular disease
    • b) positive platelets in patients with cardiovascular disease. Eur. Heart J. (1999) 20:742-747.
    • (1999) Eur. Heart J. , vol.20 , pp. 742-747
    • Goodall, A.H.1    Curzen, N.2    Panesar, M.3
  • 37
    • 0031978945 scopus 로고    scopus 로고
    • a2) is an inherited risk factor for premature myocardial infarction in coronary artery disease
    • a2) is an inherited risk factor for premature myocardial infarction in coronary artery disease. Thromb. Haemost. (1998) 79:731-735.
    • (1998) Thromb. Haemost. , vol.79 , pp. 731-735
    • Zotz, R.B.1    Winkelmann, B.R.2    Nauck, M.3
  • 38
    • 0031155630 scopus 로고    scopus 로고
    • a2) of the glycoprotein IIIa (GPIIIa) receptor is not related to myocardial infarction in the ECTIM study
    • a2) of the glycoprotein IIIa (GPIIIa) receptor is not related to myocardial infarction in the ECTIM study. Thromb. Haemost. (1997) 77:1179-1181.
    • (1997) Thromb. Haemost. , vol.77 , pp. 1179-1181
    • Herrmann, S.-M.1    Poirier, O.2    Marques-Vidal, P.3
  • 39
    • 0033608386 scopus 로고    scopus 로고
    • A1/A2 polymorphism of glycoprotein IIIa and association with excess procedural risk for coronary catheter interventions: A case-controlled study
    • LAULE M, CASCORBI I, STANGL V et al.: A1/A2 polymorphism of glycoprotein IIIa and association with excess procedural risk for coronary catheter interventions: a case-controlled study. Lancet (1999) 353:708-712.
    • (1999) Lancet , vol.353 , pp. 708-712
    • Laule, M.1    Cascorbi, I.2    Stangl, V.3
  • 40
    • 0030614495 scopus 로고    scopus 로고
    • a1/a2 polymorphism of platelet glycoprotein IIIa and risks of myocardial infarction, stroke, and venous thrombosis
    • a1/a2 polymorphism of platelet glycoprotein IIIa and risks of myocardial infarction, stroke, and venous thrombosis. Lancet (1997) 349:385-388.
    • (1997) Lancet , vol.349 , pp. 385-388
    • Ridker, P.M.1    Hennekens, C.H.2    Schmitz, C.3    Stampfer, M.J.4    Lindpaintner, K.5
  • 41
    • 0033169099 scopus 로고    scopus 로고
    • Prothrombotic genetic risk factors in young survivors of myocardial infarction
    • ARDISSINO D, MANNUCCI PM, MERLINI PA et al.: Prothrombotic genetic risk factors in young survivors of myocardial infarction. Blood (1999) 94:46-51. Excellent study approach towards identification of genetic variation in genes of the coagulation pathway in premature MI and their interaction with environmental factors.
    • (1999) Blood , vol.94 , pp. 46-51
    • Ardissino, D.1    Mannucci, P.M.2    Merlini, P.A.3
  • 44
    • 0022485106 scopus 로고
    • Haemostatic function and ischaemic heart disease: Principal results of the Northwick Park Heart study
    • MEADE TW, MELLOWS S, BROZOVIC M et al.: Haemostatic function and ischaemic heart disease: principal results of the Northwick Park Heart study. Lancet (1986) 2:533-537.
    • (1986) Lancet , vol.2 , pp. 533-537
    • Meade, T.W.1    Mellows, S.2    Brozovic, M.3
  • 46
    • 9044240867 scopus 로고    scopus 로고
    • β fibrinogen gene polymorphisms are associated with plasma fibrinogen and coronary artery disease in patients with myocardial infarction
    • BEHAGUE I, POIRIER O, NIGAUD V et al.: β fibrinogen gene polymorphisms are associated with plasma fibrinogen and coronary artery disease in patients with myocardial infarction. Circulation (1996) 93:440-449.
    • (1996) Circulation , vol.93 , pp. 440-449
    • Behague, I.1    Poirier, O.2    Nigaud, V.3
  • 47
    • 0030845155 scopus 로고    scopus 로고
    • Positive association of the β fibrinogen H1/H2 gene variation to basal fibrinogen levels and to the increase in fibrinogen concentration during acute phase reaction but not to coronary artery disease and myocardial infarction
    • GARDEMANN A, SCHWARTZ O, HABERBOSCH W et al.: Positive association of the β fibrinogen H1/H2 gene variation to basal fibrinogen levels and to the increase in fibrinogen concentration during acute phase reaction but not to coronary artery disease and myocardial infarction. Thromb. Haemost. (1997) 77:1120-1126.
    • (1997) Thromb. Haemost. , vol.77 , pp. 1120-1126
    • Gardemann, A.1    Schwartz, O.2    Haberbosch, W.3
  • 48
    • 0028961636 scopus 로고
    • 455A β-gene) is associated with differences in plasma fibrinogen levels in young men and women from different regions in Europe - Evidence for gender-genotype-environment interaction
    • 455A β-gene) is associated with differences in plasma fibrinogen levels in young men and women from different regions in Europe - evidence for gender-genotype-environment interaction. Arterioscler. Thromb. Vasc. Biol. (1995) 15:96-104.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 96-104
    • Humphries, S.E.1    Ye, S.2    Talmud, P.3    Bara, L.4    Tiret, L.5
  • 49
    • 0030816261 scopus 로고    scopus 로고
    • A prospective study of hemostatic factors and incidence of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study
    • FOLSOM AR, WU KK, ROSAMOND WD, SHARRETT AR, CHAMBLESS LE: A prospective study of hemostatic factors and incidence of coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study. Circulation (1997) 96:1102-1108.
    • (1997) Circulation , vol.96 , pp. 1102-1108
    • Folsom, A.R.1    Wu, K.K.2    Rosamond, W.D.3    Sharrett, A.R.4    Chambless, L.E.5
  • 50
    • 0028127942 scopus 로고
    • Fibrinogen and Factor VII in the prediction of coronary risk: Results from the PROCAM study in healthy men
    • HEINRICH J, BALLEISEN L, SCHULTE H, ASSMANN G, VAN DE LOO J: Fibrinogen and Factor VII in the prediction of coronary risk: results from the PROCAM study in healthy men. Arterioscler. Thromb. (1994) 14:54-59.
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 54-59
    • Heinrich, J.1    Balleisen, L.2    Schulte, H.3    Assmann, G.4    Van De Loo, J.5
  • 51
    • 0032495540 scopus 로고    scopus 로고
    • Polymorphisms in the coagulation Factor VII gene and the risk of myocardial infarction
    • IACOVIELLO L, DI CASTELNUOVO A, DE KNIJFF P et al.: Polymorphisms in the coagulation Factor VII gene and the risk of myocardial infarction. New Engl. J. Med. (1998) 338:79-85.
    • (1998) New Engl. J. Med. , vol.338 , pp. 79-85
    • Iacoviello, L.1    Di Castelnuovo, A.2    De Knijff, P.3
  • 52
    • 17344368674 scopus 로고    scopus 로고
    • Contribution of Factor VII genotype to activated FVII levels - Differences in genotype frequencies between Northern and Southern European populations
    • BERNHARDI F, ARCIERI P, BERTINA M et al.: Contribution of Factor VII genotype to activated FVII levels - differences in genotype frequencies between Northern and Southern European populations. Arterioscler. Thromb. Vasc. Biol. (1997) 17:2548-2553.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 2548-2553
    • Bernhardi, F.1    Arcieri, P.2    Bertina, M.3
  • 53
    • 0031029434 scopus 로고    scopus 로고
    • Polymorphisms of Factor V, Factor VII, and fibrinogen genes - Relevance to severity of coronary artery disease
    • WANG XL, WANG J, MCCREDIE RM, WILCKEN DEL: Polymorphisms of Factor V, Factor VII, and fibrinogen genes - relevance to severity of coronary artery disease. Arterioscler. Thromb. Vasc. Biol. (1997) 17:246-251.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 246-251
    • Wang, X.L.1    Wang, J.2    Mccredie, R.M.3    Wilcken, D.E.L.4
  • 55
    • 0030066703 scopus 로고    scopus 로고
    • Factor VII arg/GIn-353 polymorphism determines factor VII coagulant activity in patients with myocardial infarction (MI) and control subjects in Belfast and in France but is not a strong indicator of MI risk in the ECTIM study
    • LANE A, GREEN F, SCARABIN PY et al.: Factor VII arg/GIn-353 polymorphism determines factor VII coagulant activity in patients with myocardial infarction (MI) and control subjects in Belfast and in France but is not a strong indicator of MI risk in the ECTIM study. Atherosclerosis (1996) 119:119-127.
    • (1996) Atherosclerosis , vol.119 , pp. 119-127
    • Lane, A.1    Green, F.2    Scarabin, P.Y.3
  • 56
    • 0007881507 scopus 로고    scopus 로고
    • Factor VII gene polymorphism and cardiovascular disease: The Framingham Heart Study
    • FENG DL, LINDPAINTNER K, LARSON MG et al.: Factor VII gene polymorphism and cardiovascular disease: the Framingham Heart Study [abstract]. Circulation (1998) 98(Suppl. I):459.
    • (1998) Circulation , vol.98 , Issue.1 SUPPL. , pp. 459
    • Feng, D.L.1    Lindpaintner, K.2    Larson, M.G.3
  • 57
    • 16944362695 scopus 로고    scopus 로고
    • Gene polymorphisms predicting high plasma levels of coagulation and fibrinolysis proteins - A study in centenarians
    • MANNUCCI PM, MARI G, MERATI G et al.: Gene polymorphisms predicting high plasma levels of coagulation and fibrinolysis proteins - a study in centenarians. Arterioscler. Thromb. Vasc. Biol. (1997) 17:755-759.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 755-759
    • Mannucci, P.M.1    Mari, G.2    Merati, G.3
  • 58
    • 0022354051 scopus 로고
    • Increased plasma levels of a rapid inhibitor of plasminogen activator inhibitor in young survivors of myocardial infarction
    • HAMSTEN A, WIMAN B, DEFAIRE U, BLOMBACK M: Increased plasma levels of a rapid inhibitor of plasminogen activator inhibitor in young survivors of myocardial infarction. New Engl. J. Med. (1985) 313:1557-1563.
    • (1985) New Engl. J. Med. , vol.313 , pp. 1557-1563
    • Hamsten, A.1    Wiman, B.2    Defaire, U.3    Blomback, M.4
  • 59
    • 0029124975 scopus 로고
    • The 4G/5G genetic polymorphism in the promoter of the plasminogen activator inhibitor (PAI-1) gene is associated with differences in plasma PAI-1 activity but not with risk of myocardial infarction hi the ECTIM study
    • YE S, GREEN FR, SCARABIN PY et al.: The 4G/5G genetic polymorphism in the promoter of the plasminogen activator inhibitor (PAI-1) gene is associated with differences in plasma PAI-1 activity but not with risk of myocardial infarction hi the ECTIM study. Thromb. Haemost. (1995) 74:837-841.
    • (1995) Thromb. Haemost. , vol.74 , pp. 837-841
    • Ye, S.1    Green, F.R.2    Scarabin, P.Y.3
  • 60
    • 0031016432 scopus 로고    scopus 로고
    • Arterial and venous thrombosis is not associated with the 4G/5G polymorphism in the promoter of the plasminogen activator inhibitor gene in a large cohort of US men
    • RIDKER PM, HENNEKENS CH, LINDPAINTNER K, STAMPFER MJ, MILETICH JP: Arterial and venous thrombosis is not associated with the 4G/5G polymorphism in the promoter of the plasminogen activator inhibitor gene in a large cohort of US men. Circulation (1997) 95:59-62.
    • (1997) Circulation , vol.95 , pp. 59-62
    • Ridker, P.M.1    Hennekens, C.H.2    Lindpaintner, K.3    Stampfer, M.J.4    Miletich, J.P.5
  • 61
    • 85037448718 scopus 로고    scopus 로고
    • The plasminogen activator inhibitor-1 gene 4G/5G polymorphism and cardiovascular disease: The Framingham heart study
    • FENG DL, TOFLER GH, LARSON MG et al.: The plasminogen activator inhibitor-1 gene 4G/5G polymorphism and cardiovascular disease: the Framingham heart study [abstract]. J. Am. Coll. Cardiol. (1999) 33(Suppl. IA):288A-289A.
    • (1999) J. Am. Coll. Cardiol. , vol.33 , Issue.SUPPL. IA
    • Feng, D.L.1    Tofler, G.H.2    Larson, M.G.3
  • 63
    • 0032532598 scopus 로고    scopus 로고
    • The Val34Leu polymorphism in the A subunit of coagulation Factor XIII contributes to the large normal range in activity and demonstrates that the activation peptide plays a role in catalytic activity
    • KANGSADALAMPAI S, BOARD PG: The Val34Leu polymorphism in the A subunit of coagulation Factor XIII contributes to the large normal range in activity and demonstrates that the activation peptide plays a role in catalytic activity. Blood (1998) 92:2766-2770.
    • (1998) Blood , vol.92 , pp. 2766-2770
    • Kangsadalampai, S.1    Board, P.G.2
  • 64
    • 0025165779 scopus 로고
    • An insertion/deletion polymorphism in the angiotensin I-converting gene accounting for half the variance of serum levels
    • RIGAT B, ALHENC-GELAS F, CAMBIEN F, SOUBRIER F: An insertion/deletion polymorphism in the angiotensin I-converting gene accounting for half the variance of serum levels. J. Clin. Invest. (1990) 86:1343-1346.
    • (1990) J. Clin. Invest. , vol.86 , pp. 1343-1346
    • Rigat, B.1    Alhenc-Gelas, F.2    Cambien, F.3    Soubrier, F.4
  • 65
    • 0026675062 scopus 로고
    • Deletion polymorphism in the angiotensin-converting enzyme is a potent risk factor for myocardial infarction
    • CAMBIEN F, POIRIER O, LECERF L et al.: Deletion polymorphism in the angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature (1992) 359:641-644. Although polymorphisms have been studied for a long time by geneticists, this report on a clinical association between a genetic variation of the ACE gene and MI risk, started an entire new field of risk factor research in clinical medicine.
    • (1992) Nature , vol.359 , pp. 641-644
    • Cambien, F.1    Poirier, O.2    Lecerf, L.3
  • 66
    • 0030317949 scopus 로고    scopus 로고
    • Deletion polymorphism of the angiotensin I-converting enzyme gene is associated with increased plasma angiotensin-converting enzyme activity but not with increased risk for myocardial infarction and coronary artery disease
    • WINKELMANN BR, NAUCK M, KLEIN B et al.: Deletion polymorphism of the angiotensin I-converting enzyme gene is associated with increased plasma angiotensin-converting enzyme activity but not with increased risk for myocardial infarction and coronary artery disease. Ann. Intern. Med. (1996) 125:19-25.
    • (1996) Ann. Intern. Med. , vol.125 , pp. 19-25
    • Winkelmann, B.R.1    Nauck, M.2    Klein, B.3
  • 67
    • 0030910853 scopus 로고    scopus 로고
    • ACE gene polymorphism: Ischemic heart disease and longevity in 10150 individuals - A case-referent and retrospective cohort study based on the Copenhagen City Heart Study
    • AGERHOLM-LARSEN B, NORDESTGAARD BG, STEFFENSEN R, SORENSEN TIA, LENSEN G, TYBJOERKHANSEN A: ACE gene polymorphism: ischemic heart disease and longevity in 10150 individuals - a case-referent and retrospective cohort study based on the Copenhagen City Heart Study. Circulation (1997) 95:2358-2367.
    • (1997) Circulation , vol.95 , pp. 2358-2367
    • Agerholm-Larsen, B.1    Nordestgaard, B.G.2    Steffensen, R.3    Sorensen, T.I.A.4    Lensen, G.5    Tybjoerkhansen, A.6
  • 68
    • 0001501219 scopus 로고    scopus 로고
    • No association of the I/D polymorphism of the angiotensin-converting enzyme with myocardial infarction in 4941 probands
    • HOLMER SR, HENGSTENBERG C, MAYER B et al.: No association of the I/D polymorphism of the angiotensin-converting enzyme with myocardial infarction in 4941 probands [abstract]. Eur. Heart J. (1999) 20(abstract Suppl.):143.
    • (1999) Eur. Heart J. , vol.20 , Issue.ABSTRACT SUPPL. , pp. 143
    • Holmer, S.R.1    Hengstenberg, C.2    Mayer, B.3
  • 69
    • 0343850804 scopus 로고    scopus 로고
    • Large-scale test of hypothesized associations between the ACE I/D polymorphism and MI in over 10 000 cases and controls
    • KEAVNEY B, MCKENZIE C, PARISH S et al.: Large-scale test of hypothesized associations between the ACE I/D polymorphism and MI in over 10 000 cases and controls [abstract]. Eur. Heart J. (1999) 20(abstract Suppl.):143.
    • (1999) Eur. Heart J. , vol.20 , Issue.ABSTRACT SUPPL. , pp. 143
    • Keavney, B.1    Mckenzie, C.2    Parish, S.3
  • 70
    • 0030874825 scopus 로고    scopus 로고
    • Molecular genetics of human hypertension: Role of angiotensinogen
    • CORVOL P, JEUNEMAITRE X: Molecular genetics of human hypertension: role of angiotensinogen. Endocrine rev. (1997) 18:662-677. Authoritative review of the molecular genetics of angiotensinogen.
    • (1997) Endocrine Rev. , vol.18 , pp. 662-677
    • Corvol, P.1    Jeunemaitre, X.2
  • 71
    • 0030696254 scopus 로고    scopus 로고
    • Association between the angiotensinogen 235T-variant and essential hypertension in whites - A systematic review and methodological appraisal
    • KUNZ R, KREUTZ R, BEIGE J, DISTLER A, SHARMA AM: Association between the angiotensinogen 235T-variant and essential hypertension in whites - a systematic review and methodological appraisal. Hypertension (1997) 30:1331-1337.
    • (1997) Hypertension , vol.30 , pp. 1331-1337
    • Kunz, R.1    Kreutz, R.2    Beige, J.3    Distler, A.4    Sharma, A.M.5
  • 72
    • 0029051594 scopus 로고
    • Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease
    • KATSUYA T, KOIKE G, YEE TW et al.: Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease. Lancet (1995) 345:1600-1603.
    • (1995) Lancet , vol.345 , pp. 1600-1603
    • Katsuya, T.1    Koike, G.2    Yee, T.W.3
  • 73
    • 0032915912 scopus 로고    scopus 로고
    • Angiotensinogen M235T polymorphism is associated with plasma angiotensinogen and cardiovascular disease
    • WINKELMANN BR, RUSS AP, NAUCK M et al.: Angiotensinogen M235T polymorphism is associated with plasma angiotensinogen and cardiovascular disease. Am. Heart J. (1999) 137:698-705.
    • (1999) Am. Heart J. , vol.137 , pp. 698-705
    • Winkelmann, B.R.1    Russ, A.P.2    Nauck, M.3
  • 74
    • 0028952190 scopus 로고
    • Genetic variation at the angiotensinogen locus in relation to high blood pressure and myocardial infarction: The ECTIM study
    • TIRET L, RICARD S, POIRIER O et al.: Genetic variation at the angiotensinogen locus in relation to high blood pressure and myocardial infarction: the ECTIM study. J. Hyperten. (1995) 13:311-317.
    • (1995) J. Hyperten. , vol.13 , pp. 311-317
    • Tiret, L.1    Ricard, S.2    Poirier, O.3
  • 75
    • 0031056996 scopus 로고    scopus 로고
    • Associations between candidate loci angiotensin-converting enzyme and angiotensinogen with coronary heart disease and myocardial infarction: The NHLBI family heart study
    • LUDWIG EH, BORECKI IB, ELLISON RC et al.: Associations between candidate loci angiotensin-converting enzyme and angiotensinogen with coronary heart disease and myocardial infarction: the NHLBI family heart study. Ann. Epidemiol. (1997) 7:3-12.
    • (1997) Ann. Epidemiol. , vol.7 , pp. 3-12
    • Ludwig, E.H.1    Borecki, I.B.2    Ellison, R.C.3
  • 76
    • 0032497941 scopus 로고    scopus 로고
    • Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease
    • BRATTSTRÖM L, WILCKEN EL, ÖHRVIK J, BRUDIN L: Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease. Circulation (1998) 98:2520-2526.
    • (1998) Circulation , vol.98 , pp. 2520-2526
    • Brattström, L.1    Wilcken, E.L.2    Öhrvik, J.3    Brudin, L.4
  • 77
    • 0032081312 scopus 로고    scopus 로고
    • 677T mutation, plasma homocysteine, folate in subjects from northern Italy with and without angiographically documented severe coronary atherosclerotic disease: Evidence for an important genetic-environmental interaction
    • 677T mutation, plasma homocysteine, folate in subjects from northern Italy with and without angiographically documented severe coronary atherosclerotic disease: evidence for an important genetic-environmental interaction. Blood (1998) 91:4158-4163.
    • (1998) Blood , vol.91 , pp. 4158-4163
    • Girelli, D.1    Friso, S.2    Trabetti, E.3
  • 78
    • 0030826587 scopus 로고    scopus 로고
    • Thermolabile methylenetetrahydrofolate reductase in coronary artery disease
    • KLUIJTMANS LAJ, KASTELEIN JJP, LINDEMANS J et al.: Thermolabile methylenetetrahydrofolate reductase in coronary artery disease. Circulation (1997) 96:2573-2577.
    • (1997) Circulation , vol.96 , pp. 2573-2577
    • Kluijtmans, L.A.J.1    Kastelein, J.J.P.2    Lindemans, J.3
  • 79
    • 0032941872 scopus 로고    scopus 로고
    • 677T gene polymorphism is associated with the extent of coronary atherosclerosis in patients at high risk for coronary artery disease
    • 677T gene polymorphism is associated with the extent of coronary atherosclerosis in patients at high risk for coronary artery disease. Eur. Heart J. (1999) 20:584-592.
    • (1999) Eur. Heart J. , vol.20 , pp. 584-592
    • Gardemann, A.1    Weidemann, H.2    Philipp, M.3
  • 81
    • 0028940267 scopus 로고
    • Epidemiological evaluation of the use of genetics to improve the predictive value of disease risk factors
    • KHOURY MJ, WAGENER DK: Epidemiological evaluation of the use of genetics to improve the predictive value of disease risk factors. Am. J. Hum. Genet. (1995) 56:835-844.
    • (1995) Am. J. Hum. Genet. , vol.56 , pp. 835-844
    • Khoury, M.J.1    Wagener, D.K.2
  • 82
    • 6044277310 scopus 로고    scopus 로고
    • Association of genetic variation at the beta-fibrinogen gene locus and plasma fibrinogen levels: Interaction between allele frequency of the G/A-455 polymorphism, age and smoking
    • THOMAS AE, GREEN FR, HUMPHRIES SE: Association of genetic variation at the beta-fibrinogen gene locus and plasma fibrinogen levels: interaction between allele frequency of the G/A-455 polymorphism, age and smoking. Clin. Genet. (1997) 34:553-558.
    • (1997) Clin. Genet. , vol.34 , pp. 553-558
    • Thomas, A.E.1    Green, F.R.2    Humphries, S.E.3
  • 83
    • 0025754041 scopus 로고
    • Variation at the promoter of the β fibrinogen gene is associated with plasma fibrinogen levels in smokers and non-smokers
    • THOMAS AE, GREEN FR, KELLEHER CH et al: Variation at the promoter of the β fibrinogen gene is associated with plasma fibrinogen levels in smokers and non-smokers. Thromb. Haemost. (1991) 65:487-490.
    • (1991) Thromb. Haemost. , vol.65 , pp. 487-490
    • Thomas, A.E.1    Green, F.R.2    Kelleher, C.H.3
  • 84
    • 0031406428 scopus 로고    scopus 로고
    • Coronary heart disease and genetics: An epidemiologist' S view
    • CAMBIEN F, POIRIER O, MALLET C, TIRET L: Coronary heart disease and genetics: an epidemiologist' S view. Mol. Med. Today (1997) 1:197-203.
    • (1997) Mol. Med. Today , vol.1 , pp. 197-203
    • Cambien, F.1    Poirier, O.2    Mallet, C.3    Tiret, L.4
  • 85
    • 0028958950 scopus 로고
    • Genetic and environmental sources of fibrinogen variability in Israeli families: The Kibbutzim family study
    • FRIEDLANDER Y, ELKANA Y, SINNREICH R, KARK JD: Genetic and environmental sources of fibrinogen variability in Israeli families: the Kibbutzim family study. Am. J. Hum. Genet. (1995) 56:1194-1206.
    • (1995) Am. J. Hum. Genet. , vol.56 , pp. 1194-1206
    • Friedlander, Y.1    Elkana, Y.2    Sinnreich, R.3    Kark, J.D.4
  • 86
    • 0028036410 scopus 로고
    • Genetic and environmental correlations among serum lipids and apolipoproteins in elderly twins reared together and apart
    • HELLER DA, PEDERSEN NL, DEFAIRE U, MCCLEARN GE: Genetic and environmental correlations among serum lipids and apolipoproteins in elderly twins reared together and apart. Am. J. Hum. Genet. (1994) 55:1255-1267.
    • (1994) Am. J. Hum. Genet. , vol.55 , pp. 1255-1267
    • Heller, D.A.1    Pedersen, N.L.2    Defaire, U.3    Mcclearn, G.E.4
  • 87
    • 0030863012 scopus 로고    scopus 로고
    • Evidence that the apolipoprotein E-genotype effects on lipid levels can change with age in males: A longitudinal analysis
    • JARVIK GP, GOODE EL, AUSTIN MA et al.: Evidence that the apolipoprotein E-genotype effects on lipid levels can change with age in males: a longitudinal analysis. Am. J. Hum. Genet. (1997) 61:171-181.
    • (1997) Am. J. Hum. Genet. , vol.61 , pp. 171-181
    • Jarvik, G.P.1    Goode, E.L.2    Austin, M.A.3
  • 88
    • 0031024219 scopus 로고    scopus 로고
    • Sex differences in coronary heart disease - Why are women so superior [The 1995 Ancel Keys Lecture]
    • BARRET-CONNOR E: Sex differences in coronary heart disease - Why are women so superior [The 1995 Ancel Keys Lecture]. Circulation (1997) 95:252-264.
    • (1997) Circulation , vol.95 , pp. 252-264
    • Barret-Connor, E.1
  • 89
    • 0027514896 scopus 로고
    • Molecular and statistical approaches to detection and correction of errors in genotype databases
    • BRZUSTOWICZ LM, MERETTE C, XIE X, TOWNSEND L, GILLIAM TC, OTT J: Molecular and statistical approaches to detection and correction of errors in genotype databases. Am. J. Hum. Genet. (1993) 53:1137-1145.
    • (1993) Am. J. Hum. Genet. , vol.53 , pp. 1137-1145
    • Brzustowicz, L.M.1    Merette, C.2    Xie, X.3    Townsend, L.4    Gilliam, T.C.5    Ott, J.6
  • 90
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • RISCH N, MERIKANGAS K: The future of genetic studies of complex human diseases. Science (1996) 273:1516-1517.
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 91
    • 0028952250 scopus 로고
    • High-resolution genetic mapping of complex traits
    • KRUGLYAK L, LANDER ES: High-resolution genetic mapping of complex traits. Am. J. Hum. Genet. (1995) 56:1212-1223.
    • (1995) Am. J. Hum. Genet. , vol.56 , pp. 1212-1223
    • Kruglyak, L.1    Lander, E.S.2
  • 92
    • 0028025498 scopus 로고
    • Polymorphic admixture typing in human ethnic populations
    • DEAN M, STEPHENS JC, WINKLER C et al.: Polymorphic admixture typing in human ethnic populations. Am. J. Hum. Genet. (1994) 55:788-808.
    • (1994) Am. J. Hum. Genet. , vol.55 , pp. 788-808
    • Dean, M.1    Stephens, J.C.2    Winkler, C.3
  • 93
    • 0033071177 scopus 로고    scopus 로고
    • Comparison of the power and accuracy of biallelic and microsatellite markers in population-based gene-mapping methods
    • XIONG M, JIN L: Comparison of the power and accuracy of biallelic and microsatellite markers in population-based gene-mapping methods. Am. J. Hum. Genet. (1999) 64:629-640.
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 629-640
    • Xiong, M.1    Jin, L.2
  • 94
    • 0028001245 scopus 로고
    • Mapping by admixture linkage disequilibrium in human populations: Limits and guidelines
    • STEPHENS JC, BRISCOE D, O'BRIEN SJ: Mapping by admixture linkage disequilibrium in human populations: limits and guidelines. Am. J. Hum. Genet. (1994) 55:809-824.
    • (1994) Am. J. Hum. Genet. , vol.55 , pp. 809-824
    • Stephens, J.C.1    Briscoe, D.2    O'Brien, S.J.3
  • 95
    • 0033039497 scopus 로고    scopus 로고
    • Prospects for whole-genome linkage disequilibrium mapping of common disease genes
    • KRUGLYAK L: Prospects for whole-genome linkage disequilibrium mapping of common disease genes. Nature Genet. (1999) 22:139-144.
    • (1999) Nature Genet. , vol.22 , pp. 139-144
    • Kruglyak, L.1
  • 96
    • 0033073397 scopus 로고    scopus 로고
    • Power of association and linkage tests when the disease alleles arc unobserved
    • TU IP, WHITTEMORE AS: Power of association and linkage tests when the disease alleles arc unobserved. Am. J. Hum. Genet. (1999) 64:641-649.
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 641-649
    • Tu, I.P.1    Whittemore, A.S.2
  • 97
    • 0032864475 scopus 로고    scopus 로고
    • Strategies for the assessment of genetic coronary artery disease risk
    • FUNKE H, ASSMANN G: Strategies for the assessment of genetic coronary artery disease risk. Curr. Opin. Lipidol. (1999) 10:285-291.
    • (1999) Curr. Opin. Lipidol. , vol.10 , pp. 285-291
    • Funke, H.1    Assmann, G.2
  • 98
    • 0032615942 scopus 로고    scopus 로고
    • Making genomic medicine a reality [1998 ASHG presidential address]
    • BEAUDET AL: Making genomic medicine a reality [1998 ASHG presidential address]. Am. J. Hum. Genet. (1999) 64:1-13.
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 1-13
    • Beaudet, A.L.1
  • 99
    • 0000061230 scopus 로고
    • A simple approximation for calculating sample sizes for comparing independent
    • FLEISS JL, TYTUN A, URY HK: A simple approximation for calculating sample sizes for comparing independent. Biometrics (1980) 36:343-346.
    • (1980) Biometrics , vol.36 , pp. 343-346
    • Fleiss, J.L.1    Tytun, A.2    Ury, H.K.3


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