-
1
-
-
0030724591
-
Pathogenesis of Type 2 diabetes: Metabolic and molecular implications for identifying diabetes genes
-
DE FRONZO RA: Pathogenesis of Type 2 diabetes: metabolic and molecular implications for identifying diabetes genes. Diabetes Rev. (1997) 5:177-269.
-
(1997)
Diabetes Rev.
, vol.5
, pp. 177-269
-
-
De Fronzo, R.A.1
-
2
-
-
0032742992
-
The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of Type 2 diabetes mellitus
-
WEYER C, BOGARDUS C, MOTT DM, PRATLEY RE: The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of Type 2 diabetes mellitus. J. Clin. Invest. (1999) 104:787-794. Longitudinal study on a population at high risk for diabetes.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 787-794
-
-
Weyer, C.1
Bogardus, C.2
Mott, D.M.3
Pratley, R.E.4
-
3
-
-
0025094344
-
Mapping genes in diabetes: Genetic epidemiological perspective
-
RICH SS: Mapping genes in diabetes: genetic epidemiological perspective. Diabetes (1990) 39:1315-1319.
-
(1990)
Diabetes
, vol.39
, pp. 1315-1319
-
-
Rich, S.S.1
-
4
-
-
0026761432
-
Mutations in the insulin receptor gene
-
TAYLOR SI, CAMA A, ACCILI D et al.: Mutations in the insulin receptor gene. Endocrine Rev. (1992) 13:566-595. Exhaustive review on insulin receptor gene mutations.
-
(1992)
Endocrine Rev.
, vol.13
, pp. 566-595
-
-
Taylor, S.I.1
Cama, A.2
Accili, D.3
-
5
-
-
0026608764
-
Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus
-
FROGUEL P, VAXILLAIRE M, SUN F et al: Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus. Nature (1992) 356:162-161 Identification of gene mutation causing MODY.
-
(1992)
Nature
, vol.356
, pp. 162-1161
-
-
Froguel, P.1
Vaxillaire, M.2
Sun, F.3
-
6
-
-
10544249874
-
Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young
-
YAMAGATA K, ODA N, KAISAKI PJ et al.: Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young. Nature (1996) 384:455-458. Identification of gene mutation causing MODY.
-
(1996)
Nature
, vol.384
, pp. 455-458
-
-
Yamagata, K.1
Oda, N.2
Kaisaki, P.J.3
-
7
-
-
10544236911
-
Mutations in the hepatocyte nuclear factor-4 alpha gene in maturity-onset diabetes of the young
-
YAMAGATA K, FURUTA H, ODA N et al.: Mutations in the hepatocyte nuclear factor-4 alpha gene in maturity-onset diabetes of the young. Nature (1996) 384:458-460. Identification of gene mutation causing MODY.
-
(1996)
Nature
, vol.384
, pp. 458-460
-
-
Yamagata, K.1
Furuta, H.2
Oda, N.3
-
8
-
-
0031031571
-
Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
-
STOFFERS DA, ZINKIN NT, STANOJEVIC V, CLARKE WL, HABENER JF: Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nature Genet. (1997) 15:106-110. Identification of gene mutation causing agenesis of pancreas.
-
(1997)
Nature Genet.
, vol.15
, pp. 106-110
-
-
Stoffers, D.A.1
Zinkin, N.T.2
Stanojevic, V.3
Clarke, W.L.4
Habener, J.F.5
-
9
-
-
0029088719
-
Glucose-induced insulin receptor tyrosinc phosphorylation in insulin-secreting beta-cells
-
ROTHENBERG PL, WILLISON LD, SIMON J, WOLF BA: Glucose-induced insulin receptor tyrosinc phosphorylation in insulin-secreting beta-cells. Diabetes (1995) 44:802-609.
-
(1995)
Diabetes
, vol.44
, pp. 802-1609
-
-
Rothenberg, P.L.1
Willison, L.D.2
Simon, J.3
Wolf, B.A.4
-
10
-
-
0032587076
-
972→Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic β-cells
-
972→Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic β-cells. J. Clin. Invest. (1999) 104:357-364. Identification of gene defect in insulin signaling causing β-cell dysfunction.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 357-364
-
-
Porzio, O.1
Federici, M.2
Hribal, M.L.3
-
11
-
-
0033379267
-
Altered function of insulin receptor substrate-1-deficient mouse islets and cultured β-cell lines
-
KULKARNI RH, WINNAY JN, DANIELS M et al. Altered function of insulin receptor substrate-1-deficient mouse islets and cultured β-cell lines. J. Clin. Invest. (1999) 104:R69-R75.
-
(1999)
J. Clin. Invest.
, vol.104
-
-
Kulkarni, R.H.1
Winnay, J.N.2
Daniels, M.3
-
12
-
-
0033524937
-
Tissue-specific knockout of the insulin receptor in pancreatic β cells creates an insulin secretory defect similar to that in Type 2 diabetes
-
KULKARNI RN, BRUNING JC, WINNAY JN, POSTIC C, MAGNUSON MA, KAHN CR: Tissue-specific knockout of the insulin receptor in pancreatic β cells creates an insulin secretory defect similar to that in Type 2 diabetes. Cell (1999) 96:329-339. Animal model of Type 2 diabetes.
-
(1999)
Cell
, vol.96
, pp. 329-339
-
-
Kulkarni, R.N.1
Bruning, J.C.2
Winnay, J.N.3
Postic, C.4
Magnuson, M.A.5
Kahn, C.R.6
-
13
-
-
0030748457
-
The insulin signalling system and the IRS proteins
-
WHITE MF: The insulin signalling system and the IRS proteins. Diabetologia (1997) 40:S2-S17.
-
(1997)
Diabetologia
, vol.40
-
-
White, M.F.1
-
14
-
-
0021985413
-
Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
-
ULLRICH A, BELL JR, CHEN EY et al: Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes. Nature (1985) 313:756-761. Cloning of the human insulin receptor.
-
(1985)
Nature
, vol.313
, pp. 756-761
-
-
Ullrich, A.1
Bell, J.R.2
Chen, E.Y.3
-
15
-
-
0021924895
-
The structural basis for hormone-activated transmembrane signalling
-
EBINA Y, ELLIS L, JARNAGIN K et al.: The structural basis for hormone-activated transmembrane signalling. Cell (1985) 40:747-758. Cloning of the human insulin receptor.
-
(1985)
Cell
, vol.40
, pp. 747-758
-
-
Ebina, Y.1
Ellis, L.2
Jarnagin, K.3
-
16
-
-
0024548162
-
Structure of the human insulin receptor gene and characterization of its promoter
-
SEINO S, SEINO M, NISHI S, BELL GI: Structure of the human insulin receptor gene and characterization of its promoter. Proc. Natl. Acad. Sci. USA (1989) 86:114-118.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 114-118
-
-
Seino, S.1
Seino, M.2
Nishi, S.3
Bell, G.I.4
-
17
-
-
0032504250
-
Expression and characterization of a 70-kDa fragment of the insulin receptor that binds insulin
-
KRISTENSEN C, WIBERG FC, SCHAFFER L, ANDERSEN AS: Expression and characterization of a 70-kDa fragment of the insulin receptor that binds insulin. J. Biol. Chem. (1998) 273:17780-17786.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17780-17786
-
-
Kristensen, C.1
Wiberg, F.C.2
Schaffer, L.3
Andersen, A.S.4
-
18
-
-
0028319209
-
Tissue-specific expression of two alternatively spliced isoforms of the human insulin receptor protein
-
SESTI G, TULLIO AN, D'ALFONSO R et al.: Tissue-specific expression of two alternatively spliced isoforms of the human insulin receptor protein. Acta Diabetologica (1994) 31:59-65
-
(1994)
Acta Diabetologica
, vol.31
, pp. 59-65
-
-
Sesti, G.1
Tullio, A.N.2
D'Alfonso, R.3
-
19
-
-
0025362295
-
Functionally distinct insulin receptors generated by tissue-specific alternative splicing
-
MOSTHAF L, GRAKO D, DULL TJ, COUSSENS L, ULLRICH A, MCCLAIN DA: Functionally distinct insulin receptors generated by tissue-specific alternative splicing. EMBO J. (1990) 9:2-409-2413. Characterisation of functional differences between the two insulin receptor forms.
-
(1990)
EMBO J.
, vol.9
-
-
Mosthaf, L.1
Grako, D.2
Dull, T.J.3
Coussens, L.4
Ullrich, A.5
Mcclain, D.A.6
-
20
-
-
0025773690
-
The two isotypes of the human insulin receptor (HIR-A and HIR-B) follow different internalization kinetics
-
VOGT B, CARRASCOSA JM, ERMEL B, ULLRICH A, HARING HU: The two isotypes of the human insulin receptor (HIR-A and HIR-B) follow different internalization kinetics. Biochem. Biophys. Res. Comm. (1991) 177:1013-1018.
-
(1991)
Biochem. Biophys. Res. Comm.
, vol.177
, pp. 1013-1018
-
-
Vogt, B.1
Carrascosa, J.M.2
Ermel, B.3
Ullrich, A.4
Haring, H.U.5
-
21
-
-
0025941580
-
Functional properties of two naturally occurring isoforms of the human insulin receptor in Chinese hamster ovary cells
-
YAMAGUCHI Y, FLIER JS, YOKOTA A, BENECKE H, BACKER JM, MOLLER DE: Functional properties of two naturally occurring isoforms of the human insulin receptor in Chinese hamster ovary cells. Endocrinology (1991) 129:2058-2066.
-
(1991)
Endocrinology
, vol.129
, pp. 2058-2066
-
-
Yamaguchi, Y.1
Flier, J.S.2
Yokota, A.3
Benecke, H.4
Backer, J.M.5
Moller, D.E.6
-
22
-
-
0025867117
-
Different ligand affinities of the two human insulin receptor splice variants arc reflected in parallel changes in sensitivity for insulin action
-
MCCLAIN DA: Different ligand affinities of the two human insulin receptor splice variants arc reflected in parallel changes in sensitivity for insulin action. Mol. Endocrinol. (1991) 5:734-739.
-
(1991)
Mol. Endocrinol.
, vol.5
, pp. 734-739
-
-
Mcclain, D.A.1
-
23
-
-
0026515975
-
Evidence that two naturally occurring human insulin receptor α-subunit variants arc immunologically distinct
-
SESTI G, MARINI MA, MONTEMURRO A et al.: Evidence that two naturally occurring human insulin receptor α-subunit variants arc immunologically distinct. Diabetes (1992) 41:6-11. Immunological differences between the two insulin receptor forms.
-
(1992)
Diabetes
, vol.41
, pp. 6-11
-
-
Sesti, G.1
Marini, M.A.2
Montemurro, A.3
-
24
-
-
0027537050
-
Ligand-binding properties of the two isoforms of the human insulin receptor
-
YAMAGUCHI Y, FLIER JS, BENECKE H, RANSIL BJ, MOLLER DE: Ligand-binding properties of the two isoforms of the human insulin receptor. Endocrinology (1993) 132:1132-1138.
-
(1993)
Endocrinology
, vol.132
, pp. 1132-1138
-
-
Yamaguchi, Y.1
Flier, J.S.2
Benecke, H.3
Ransil, B.J.4
Moller, D.E.5
-
25
-
-
0028256417
-
Role of the exon 11 of the insulin receptor gene on insulin binding identified by anti-peptide antibodies
-
SESTI G, TULLIO AN, MARINI MA et al.: Role of the exon 11 of the insulin receptor gene on insulin binding identified by anti-peptide antibodies. Mol. Cell Endocrinol. (1994) 101:121-127.
-
(1994)
Mol. Cell Endocrinol.
, vol.101
, pp. 121-127
-
-
Sesti, G.1
Tullio, A.N.2
Marini, M.A.3
-
26
-
-
0028082506
-
Regulation of human insulin receptor RNA splicing in vivo
-
NORGREN S, ZIERATH J, WEDELL A, WALLEBERG-HENRIKSSON H, LUTHMAN H: Regulation of human insulin receptor RNA splicing in vivo. Proc. Natl. Acad. Sci. USA (1994) 91:1465-1469.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 1465-1469
-
-
Norgren, S.1
Zierath, J.2
Wedell, A.3
Walleberg-Henriksson, H.4
Luthman, H.5
-
27
-
-
0028243947
-
Regulation of human insulin receptor RNA splicing in HepG2 cells: Effects of glucocorticoid and low glucose concentration
-
NORGREN S, SHENG LI L, LUTHMAN H: Regulation of human insulin receptor RNA splicing in HepG2 cells: effects of glucocorticoid and low glucose concentration. Biochem. Biophys. Res. Comm. (1994) 199:277-284.
-
(1994)
Biochem. Biophys. Res. Comm.
, vol.199
, pp. 277-284
-
-
Norgren, S.1
Sheng, L.I.L.2
Luthman, H.3
-
28
-
-
0028985958
-
Peptide-based radioimmunoassay for the two isoforms of the human insulin receptor
-
SESTI G, D'ALFONSO R, VARGAS PUNTI MD et al.: Peptide-based radioimmunoassay for the two isoforms of the human insulin receptor. Diabetologia (1995) 38:445-453. Quantitation of the two insulin receptor protein forms in Type 2 diabetes.
-
(1995)
Diabetologia
, vol.38
, pp. 445-453
-
-
Sesti, G.1
D'Alfonso, R.2
Vargas Punti, M.D.3
-
29
-
-
0022800838
-
Insulin-like growth factor 1 receptor primary structure: Comparision with insulin receptor suggests structural determinants that define functional specificity
-
ULLRICH A, GRAY A, TAM AW et al.: Insulin-like growth factor 1 receptor primary structure: comparision with insulin receptor suggests structural determinants that define functional specificity. EMBO J. (1986) 5:2503-2512. Cloning of the IGF-I receptor.
-
(1986)
EMBO J.
, vol.5
, pp. 2503-2512
-
-
Ullrich, A.1
Gray, A.2
Tam, A.W.3
-
30
-
-
0024465470
-
Immunological relationships between receptors for insulin and insulin-like growth factor-I
-
SOOS MA, SIDDLE K: Immunological relationships between receptors for insulin and insulin-like growth factor-I. Biochem. J. (1989) 263:553-563.
-
(1989)
Biochem. J.
, vol.263
, pp. 553-563
-
-
Soos, M.A.1
Siddle, K.2
-
31
-
-
0027730575
-
Characterization of human placental insulin-like growth factor-I/insulin hybrid receptors by protein microsequencing and purification
-
KASUYA J, PAZ B, MADDUX BA, GOLDFINE ID, HEFTA SA, FUJITA-YAMAGUCHI Y: Characterization of human placental insulin-like growth factor-I/insulin hybrid receptors by protein microsequencing and purification. Biochemistry (1993) 32:13531-13536.
-
(1993)
Biochemistry
, vol.32
, pp. 13531-13536
-
-
Kasuya, J.1
Paz, B.2
Maddux, B.A.3
Goldfine, I.D.4
Hefta, S.A.5
Fujita-Yamaguchi, Y.6
-
32
-
-
0025131648
-
Receptor for insulin and insulin-life growth factor-I can form hybrid dimers
-
SOOS MA, WHITTAKER J, LAMMERS R, ULLRICH A, SIDDLE K: Receptor for insulin and insulin-life growth factor-I can form hybrid dimers. Biochem. J. (1990) 270:383-390.
-
(1990)
Biochem. J.
, vol.270
, pp. 383-390
-
-
Soos, M.A.1
Whittaker, J.2
Lammers, R.3
Ullrich, A.4
Siddle, K.5
-
33
-
-
0024816512
-
Assembly of insulin/insulin-like growth factor-I hybrid receptors in vitro
-
TREADWAY JL, MORRISON B, GOLDFINE ID, PESSIN JE: Assembly of insulin/insulin-like growth factor-I hybrid receptors in vitro. J. Biol. Chem. (1989) 264:21450-21453.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 21450-21453
-
-
Treadway, J.L.1
Morrison, B.2
Goldfine, I.D.3
Pessin, J.E.4
-
34
-
-
0027502045
-
Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity
-
SOOS MA, FIELD CE, SIDDLE K: Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity. Biochem. J. (1993) 290:419-426. Functional characterisation of insulin/insulin-like growth factor-I hybrid receptors.
-
(1993)
Biochem. J.
, vol.290
, pp. 419-426
-
-
Soos, M.A.1
Field, C.E.2
Siddle, K.3
-
35
-
-
0028899887
-
Functional characterization of hybrid receptors composed of a truncated insulin receptor and wild Type insulin-like growth factor 1 or insulin receptor
-
LANGLOIS WJ, SASAOKA T, YIP CC, OLEFSKY JM: Functional characterization of hybrid receptors composed of a truncated insulin receptor and wild Type insulin-like growth factor 1 or insulin receptor. Endocrinology (1995) 136:1978-1986. Functional characterisation of insulin/insulin-like growth factor-I hybrid receptors.
-
(1995)
Endocrinology
, vol.136
, pp. 1978-1986
-
-
Langlois, W.J.1
Sasaoka, T.2
Yip, C.C.3
Olefsky, J.M.4
-
36
-
-
0028964601
-
A functional assessment of insulin/insulin-like Growth Factor-I hybrid receptors
-
SEELY BL, REICHART DR, TAKATA Y, YIP CC, OLEFSKY JM: A functional assessment of insulin/insulin-like Growth Factor-I hybrid receptors. Endocrinology (1995) 136:1635-1641.
-
(1995)
Endocrinology
, vol.136
, pp. 1635-1641
-
-
Seely, B.L.1
Reichart, D.R.2
Takata, Y.3
Yip, C.C.4
Olefsky, J.M.5
-
37
-
-
0030996802
-
Distribution of insulin/insulin-like growth factor-I hybrid receptors in human tissues
-
FEDERICI M, PORZIO O, ZUCARO L et al.: Distribution of insulin/insulin-like growth factor-I hybrid receptors in human tissues. Mol. Cell. Endocrinol. (1997) 129:121-126.
-
(1997)
Mol. Cell. Endocrinol.
, vol.129
, pp. 121-126
-
-
Federici, M.1
Porzio, O.2
Zucaro, L.3
-
38
-
-
0030693249
-
Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: Quantification of individual receptor species by selective immunoprecipitation and immunoblotting
-
BAILYES EM, NAVE BT, SOOS MA, ORR SR, HAYWARD AC, SIDDLE K: Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and immunoblotting. Biochem. J. (1997) 327:209-215.
-
(1997)
Biochem. J.
, vol.327
, pp. 209-215
-
-
Bailyes, E.M.1
Nave, B.T.2
Soos, M.A.3
Orr, S.R.4
Hayward, A.C.5
Siddle, K.6
-
39
-
-
0031965286
-
Expression of insulin/IGF-I hybrid receptors is increased in skeletal muscle of patients with chronic primary hyperinsulinemia
-
FEDERICI M, LAURO D, D'ADAMO M et al.: Expression of insulin/IGF-I hybrid receptors is increased in skeletal muscle of patients with chronic primary hyperinsulinemia. Diabetes (1998) 47:87-92.
-
(1998)
Diabetes
, vol.47
, pp. 87-92
-
-
Federici, M.1
Lauro, D.2
D'Adamo, M.3
-
40
-
-
0031727326
-
Increased abundance of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of obese subjects is correlated with in vivo insulin sensitivity
-
FEDERICI M, PORZIO O, LAURO D et al.: Increased abundance of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of obese subjects is correlated with in vivo insulin sensitivity. J. Clin. Endocrinol. Metab. (1998) 83:2911-2915.
-
(1998)
J. Clin. Endocrinol. Metab.
, vol.83
, pp. 2911-2915
-
-
Federici, M.1
Porzio, O.2
Lauro, D.3
-
41
-
-
18244413454
-
Evidences for Glucose/Hexosamine in vivo Regulation of Insulin/IGF-I Hybrid Receptors Assembly
-
FEDERICI M, GIACCARI A, HRIBAL ML et al.: Evidences for Glucose/Hexosamine In vivo Regulation of Insulin/IGF-I Hybrid Receptors Assembly. Diabetes (1999) 48:2277-2285.
-
(1999)
Diabetes
, vol.48
, pp. 2277-2285
-
-
Federici, M.1
Giaccari, A.2
Hribal, M.L.3
-
42
-
-
0032143831
-
Expression and function of insulin/insulin-like growth factor I hybrid receptors during differentiation of 3T3-L1 preadipocytes
-
MODAN-MOSES D, JANICOT M, MCLENITHAN JC, LANE MD, CASELLA SJ: Expression and function of insulin/insulin-like growth factor I hybrid receptors during differentiation of 3T3-L1 preadipocytes. Blochem. J. (1998) 333:825-831.
-
(1998)
Blochem. J.
, vol.333
, pp. 825-831
-
-
Modan-Moses, D.1
Janicot, M.2
Mclenithan, J.C.3
Lane, M.D.4
Casella, S.J.5
-
43
-
-
0024461052
-
Normal insulin receptor cDNA sequence in Pima Indians with NIDDM
-
MOLLER DE, YOKOTA A, FLIER JS: Normal insulin receptor cDNA sequence in Pima Indians with NIDDM. Diabetes (1989) 38:1496-1500.
-
(1989)
Diabetes
, vol.38
, pp. 1496-1500
-
-
Moller, D.E.1
Yokota, A.2
Flier, J.S.3
-
44
-
-
0002760776
-
Unconfirmed polymorphisms in the human insulin receptor gene
-
D'ALFONSO R, FUSCO A, NAPOLITANO ML et al: Unconfirmed polymorphisms in the human insulin receptor gene. Exp. Clin. Endocrinol. (1993) 101 (Suppl. 2):52-53.
-
(1993)
Exp. Clin. Endocrinol.
, vol.101
, Issue.2 SUPPL.
, pp. 52-53
-
-
D'Alfonso, R.1
Fusco, A.2
Napolitano, M.L.3
-
45
-
-
0025896884
-
Detection of mutations in insulin-receptor gene in NIDDM patients by analysis of single-stranded conformational polymorphisms
-
O'RAHILLY J, CHOI WH, PATEL P, TURNER RC, FLIER JS, MOLLER DE: Detection of mutations in insulin-receptor gene in NIDDM patients by analysis of single-stranded conformational polymorphisms. Diabetes (1991) 40:777-782.
-
(1991)
Diabetes
, vol.40
, pp. 777-782
-
-
O'Rahilly, J.1
Choi, W.H.2
Patel, P.3
Turner, R.C.4
Flier, J.S.5
Moller, D.E.6
-
46
-
-
0030820114
-
A 973 valine to methionine mutation of the human insulin receptor: Interaction with insulin-receptor substrate-1 and She in HEK 293 cells
-
STRACK V, BOSSENMAIER B, STOYANOV B, MUSHACK J, HARING HU: A 973 valine to methionine mutation of the human insulin receptor: interaction with insulin-receptor substrate-1 and She in HEK 293 cells. Diabetologia (1997) 40:1135-1140.
-
(1997)
Diabetologia
, vol.40
, pp. 1135-1140
-
-
Strack, V.1
Bossenmaier, B.2
Stoyanov, B.3
Mushack, J.4
Haring, H.U.5
-
47
-
-
0025801714
-
Altered expression of insulin receptor types a and B in the skeletal muscle of non-insulin-dependent diabetes mellitus
-
MOSTHAF L, VOGT B, HARING HU, ULLRICH A: Altered expression of insulin receptor types A and B in the skeletal muscle of non-insulin-dependent diabetes mellitus. Proc. Natl. Acad. Sci. USA (1991) 88:4728-4730.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 4728-4730
-
-
Mosthaf, L.1
Vogt, B.2
Haring, H.U.3
Ullrich, A.4
-
48
-
-
0027466331
-
Insulin receptor isotypes expression correlates with risk of non-insulin-dependent diabetes mellitus
-
MOSTHAF L, ERIKSSON J, HARING HU, GROOP L, WIDEN E, ULLRICH A: Insulin receptor isotypes expression correlates with risk of non-insulin-dependent diabetes mellitus. Proc. Natl. Acad. Sci. USA (1993) 90:2633-2635.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2633-2635
-
-
Mosthaf, L.1
Eriksson, J.2
Haring, H.U.3
Groop, L.4
Widen, E.5
Ullrich, A.6
-
49
-
-
0027174141
-
Differences in the ratio of RNA encoding two isoforms of the insulin receptor between control and NIDDM patients
-
NORGREN S, ZIERATH J, GALUSKA D, WALLEBERG-HENRIKSSON H, LUTHMAN H: Differences in the ratio of RNA encoding two isoforms of the insulin receptor between control and NIDDM patients. Diabetes (1993) 42:675-681.
-
(1993)
Diabetes
, vol.42
, pp. 675-681
-
-
Norgren, S.1
Zierath, J.2
Galuska, D.3
Walleberg-Henriksson, H.4
Luthman, H.5
-
50
-
-
0026652518
-
Alternatively spliced variants of the human insulin receptor protein
-
BENECKE H, FLIER JS, MOLLER DE: Alternatively spliced variants of the human insulin receptor protein. J. Clin. Invest. (1992) 89:2066-2070.
-
(1992)
J. Clin. Invest.
, vol.89
, pp. 2066-2070
-
-
Benecke, H.1
Flier, J.S.2
Moller, D.E.3
-
51
-
-
0027298157
-
Relative expression of insulin receptor isoforms does not differ in lean, obese, and noninsulin-dependent diabetes mellitus subjects
-
ANDERSON CM, HENRY RR, KNUDSON PE, OLESKY JM, WEBSTER NJG: Relative expression of insulin receptor isoforms does not differ in lean, obese, and noninsulin-dependent diabetes mellitus subjects. J. Clin. Endocrinol. Metab. (1993) 72:1380-1383.
-
(1993)
J. Clin. Endocrinol. Metab.
, vol.72
, pp. 1380-1383
-
-
Anderson, C.M.1
Henry, R.R.2
Knudson, P.E.3
Olesky, J.M.4
Webster, N.J.G.5
-
52
-
-
0027139759
-
Expression of insulin receptor spliced variants and their functional correlates in muscle from patients with non-insulin-dependent diabetes mellitus
-
HANSEN T, BJORBAEK C, VESTERGAARD H, GRONSKOV K, BAK JF, PEDERSEN O: Expression of insulin receptor spliced variants and their functional correlates in muscle from patients with non-insulin-dependent diabetes mellitus. J. Clin. Endocrinol. Metab. (1993) 77:1500-1505.
-
(1993)
J. Clin. Endocrinol. Metab.
, vol.77
, pp. 1500-1505
-
-
Hansen, T.1
Bjorbaek, C.2
Vestergaard, H.3
Gronskov, K.4
Bak, J.F.5
Pedersen, O.6
-
53
-
-
0026348452
-
Altered expression of the two naturally occurring human insulin receptor variants in isolated adipocytes of non-insulin-dependent diabetes mellitus patients. Biochem
-
SESTI G, MARINI MA, TULLIO AN et al.: Altered expression of the two naturally occurring human insulin receptor variants in isolated adipocytes of non-insulin-dependent diabetes mellitus patients. Biochem. Biophys. Res. Comm. (1991) 181:1419-1424.
-
(1991)
Biophys. Res. Comm.
, vol.181
, pp. 1419-1424
-
-
Sesti, G.1
Marini, M.A.2
Tullio, A.N.3
-
54
-
-
0027322636
-
Altered pattern of insulin receptor isotypes in skeletal muscle membranes of Type II (non-insulin-dependent) diabetic subjects
-
KELLERER M, SESTI G, SEFFER E et al: Altered pattern of insulin receptor isotypes in skeletal muscle membranes of Type II (non-insulin-dependent) diabetic subjects. Diabetologia (1993) 36:628-632.
-
(1993)
Diabetologia
, vol.36
, pp. 628-632
-
-
Kellerer, M.1
Sesti, G.2
Seffer, E.3
-
55
-
-
0030070611
-
Chronic primart hyperinsulinemia is associated with altered insulin receptor mRNA splicing in muscle of patients with insulinoma
-
SBRACCIA P, D'ADAMO M, LEONETTI F et al.: Chronic primart hyperinsulinemia is associated with altered insulin receptor mRNA splicing in muscle of patients with insulinoma. Diabetoligia (1993) 39:220-225.
-
(1993)
Diabetoligia
, vol.39
, pp. 220-225
-
-
Sbraccia, P.1
D'Adamo, M.2
Leonetti, F.3
-
56
-
-
0030453978
-
Increased expression of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of non-insulin-dependent diabetes mellitus subjects
-
FEDERICI M, ZUCAKO L, PORZIO O et al.: Increased expression of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of non-insulin-dependent diabetes mellitus subjects. J. Clin. Invest. (1996) 98:2887-2893. Evaluation of insulin/insulin-like growth factor-I hybrid receptors in Type 2 diabetes.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 2887-2893
-
-
Federici, M.1
Zucako, L.2
Porzio, O.3
-
57
-
-
0031434946
-
Increased abundance of insulin/IGF-I hybrid receptors in adipose tissue from NIDDM patients
-
FEDERICI M, PORZIO O, ZUCARO L et al.: Increased abundance of insulin/IGF-I hybrid receptors in adipose tissue from NIDDM patients. Mol. Cell. Endocrinol. (1997) 135:41-47.
-
(1997)
Mol. Cell. Endocrinol.
, vol.135
, pp. 41-47
-
-
Federici, M.1
Porzio, O.2
Zucaro, L.3
-
58
-
-
0029888364
-
Increased expression of low-affinity insulin receptor isoform and insulin/insulin-like growth factor-I hybrid receptors in term placenta from insulin resistant women with gestational hypertension
-
VALENSISE H, LIU YY, FEDERICI M et al.: Increased expression of low-affinity insulin receptor isoform and insulin/insulin-like growth factor-I hybrid receptors in term placenta from insulin resistant women with gestational hypertension. Diabetologia (1996) 39:952-960.
-
(1996)
Diabetologia
, vol.39
, pp. 952-960
-
-
Valensise, H.1
Liu, Y.Y.2
Federici, M.3
-
59
-
-
0025267789
-
Cloning of insulin receptor cDNA from an insulin resistant Pima Indian
-
CAMA A, PATTERSON A, KADOWAKI T et al.: Cloning of insulin receptor cDNA from an insulin resistant Pima Indian. J. Clin. Endocrinol. Metab. (1990) 70:1155-1161.
-
(1990)
J. Clin. Endocrinol. Metab.
, vol.70
, pp. 1155-1161
-
-
Cama, A.1
Patterson, A.2
Kadowaki, T.3
-
60
-
-
0026056521
-
Analysis of the gene sequences of the insulin receptor and insulin-sensitive glucose transporter (GLUT-4) in patients with common-type non-insulin-dependent diabetes mellitus
-
KUSARI J, VERMA US, BUSE JB, HENRY RR, OLEFSKY JM: Analysis of the gene sequences of the insulin receptor and insulin-sensitive glucose transporter (GLUT-4) in patients with common-type non-insulin-dependent diabetes mellitus. J Clin. Invest. (1991) 88:1323-1330.
-
(1991)
J Clin. Invest.
, vol.88
, pp. 1323-1330
-
-
Kusari, J.1
Verma, U.S.2
Buse, J.B.3
Henry, R.R.4
Olefsky, J.M.5
-
61
-
-
0026578215
-
Insulin receptor and insulin-responsive glucose transportr (GLUT-4) mutations and polymorphisms in a Welsh Type 2 (non-insulin-dependent) diabetic population
-
O'RAHILLY J, KROOK, MORGAN R, REES A, FLIER JS, MOLLER DE: Insulin receptor and insulin-responsive glucose transportr (GLUT-4) mutations and polymorphisms in a Welsh Type 2 (non-insulin-dependent) diabetic population. Diabetologia (1992) 35:486-489.
-
(1992)
Diabetologia
, vol.35
, pp. 486-489
-
-
O'Rahilly, J.1
Krook2
Morgan, R.3
Rees, A.4
Flier, J.S.5
Moller, D.E.6
-
62
-
-
0030923338
-
The val985met insulin-receptor variant in the Danish Caucasian population: Lack of associations with non-insulin-dependent diabetes mellitus or insulin resistance
-
HANSEN L, HANSEN T, CLAUSEN JO et al.: The val985met insulin-receptor variant in the Danish Caucasian population: lack of associations with non-insulin-dependent diabetes mellitus or insulin resistance. Am. J. Hum. Genet. (.1997) 60:1532-1535.
-
(1997)
Am. J. Hum. Genet.
, vol.60
, pp. 1532-1535
-
-
Hansen, L.1
Hansen, T.2
Clausen, J.O.3
-
63
-
-
0029907562
-
Association of the insulin-receptor variant Met-985 with hyperglycemia and non-insulin-dependent diabetes mellitus in the Netherlands: A population-based study
-
'T HART LM, STOLK RP, HEINE RJ, GROBBEE DE, VAN DER DOES FE, MAASSEN JA: Association of the insulin-receptor variant Met-985 with hyperglycemia and non-insulin-dependent diabetes mellitus in the Netherlands: a population-based study. Am. J. Hum. Genet. (1996) 59:1119-1125.
-
(1996)
Am. J. Hum. Genet.
, vol.59
, pp. 1119-1125
-
-
'T Hart, L.M.1
Stolk, R.P.2
Heine, R.J.3
Grobbee, D.E.4
Van Der Does, F.E.5
Maassen, J.A.6
-
64
-
-
0032988612
-
Prevalence of variants in candidate genes for Type 2 diabetes mellitus in the Netherlands: The Rotterdam study and the Hoorn study
-
'T HART LM, STOLK RP, DEKKER JM et al.: Prevalence of variants in candidate genes for Type 2 diabetes mellitus in the Netherlands: the Rotterdam study and the Hoorn study. J Clin. Endocrinol. Metab. (1999) 84:1002-1006.
-
(1999)
J Clin. Endocrinol. Metab.
, vol.84
, pp. 1002-1006
-
-
'T Hart, L.M.1
Stolk, R.P.2
Dekker, J.M.3
-
65
-
-
0026766040
-
NIDDM associated with mutation in tyrosine kinase domain of insulin receptor gene
-
COCOZZA S, PORCELLINI A, RICCARDI G et al.: NIDDM associated with mutation in tyrosine kinase domain of insulin receptor gene. Diabetes (1992) 41:521-526.
-
(1992)
Diabetes
, vol.41
, pp. 521-526
-
-
Cocozza, S.1
Porcellini, A.2
Riccardi, G.3
-
66
-
-
0027327142
-
Defective insulin action in fibroblasts from noninsulin-dependent diabetes mellitus patients with Gln 1152 insulin receptor mutation
-
PETRUZZIELLO A, FORMISANO P, MIELE C et al.: Defective insulin action in fibroblasts from noninsulin-dependent diabetes mellitus patients with Gln 1152 insulin receptor mutation. J. Clin. Endocrinol. Metab. (1993) 77:409-412.
-
(1993)
J. Clin. Endocrinol. Metab.
, vol.77
, pp. 409-412
-
-
Petruzziello, A.1
Formisano, P.2
Miele, C.3
-
67
-
-
0028822448
-
Frequency of mutations of insulin receptor gene in Japanese patients with NIDDM
-
KAN M, KANAI F, IIDA M et al.: Frequency of mutations of insulin receptor gene in Japanese patients with NIDDM. Diabetes (1995) 44:1081-1086.
-
(1995)
Diabetes
, vol.44
, pp. 1081-1086
-
-
Kan, M.1
Kanai, F.2
Iida, M.3
|