A 973 valine to methionine mutation of the human insulin receptor: Interaction with insulin,receptor substrate-1 and Shc in HEK 293 cells

Diabetologia

Volumn 40, Issue 10, 1997, Pages 1135-1140

  Strack, V ^a   Bossenmaier, B ^b   Stoyanov, B ^a   Mushack, J ^a   Haring H U ^a,c  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

^c Endokrinologie S und P   (Germany)

Author keywords

Hyperglycaemia; Insulin receptor; Mutation; NIDDM; PI3 kinase; Substrate phosphorylation

Indexed keywords

INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; METHIONINE; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; VALINE;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESISTANCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIMETABOLITES; BLOTTING, WESTERN; CELL LINE; DEOXYGLUCOSE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IMMUNE SERA; INSULIN; MICE; MUTATION; PHOSPHOPROTEINS; PHOSPHORYLATION; RABBITS; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; TRANSFECTION;

EID: 0030820114     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250050798     Document Type: Article

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