The role of chemokines in Hodgkin's disease

Leukemia and Lymphoma

Volumn 38, Issue 3-4, 2000, Pages 363-371

  Teruya Feldstein, Julie ^a   Tosato, Giovanna ^c   Jaffe, Elaine S ^b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

Chemokines; Eotaxin; Hodgkin's disease; IP 10; MIP1 ; Rantes

Indexed keywords

ALPHA CHEMOKINE; CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; RANTES;

ARTICLE; CLINICAL ARTICLE; EOSINOPHILIA; EPSTEIN BARR VIRUS; FIBROBLAST; HODGKIN DISEASE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; LYMPHOCYTIC INFILTRATION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REED STERNBERG CELL; T LYMPHOCYTE; TISSUE DISTRIBUTION; VASCULAR SMOOTH MUSCLE;

EID: 0034123034     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428190009087027     Document Type: Article

References (68)

1. Teruya-Feldstein, J., Jaffe, E.S., Burd, P.R., Kingma, D.W., Setsuda, J.E. and Tosato, G. (1999) Differential chemokine expression in tissues involved by Hodgkin's disease: direct correlation of eotaxin expression and tissue eosinophilia. Blood, 93, 2463-2470.
2. Rollins, B.J. (1997) Chemokines. Blood, 90, 909-928.
3. Baggiolini, M. (1998) Chemokines and leukocyte traffic. Nature, 392, 565-568.
4. Luster, A.D. (1998) Chemokines - chemotactic cytokines that mediate inflammation. N Engl J Med, 338, 436-445.
5. Gruss, H.J., Herrmann, F. and Drexler, H.G. (1994) Hodgkin's disease: a cytokine-producing tumor - a review. Crit Rev Oncog, 5, 473-538.
6. Gorschluter, M., Bohlen, H., Hasenclever, D., Diehl, V. and Tesch, H. (1995) Serum cytokine levels correlate with clinical parameters in Hodgkin's disease. Ann Oncol, 6, 477-482.
7. Foss, H.D., Herbst, H., Gottstein, S., Demel, G., Araujo, I. and Stein, H. (1996) Interleukin-8 in Hodgkin's disease. Preferential expression by reactive cells and association with neutrophil density. Am J Pathol, 148, 1229-1236.
8. Gruss, H.J., Pinto, A., Duyster, J., Poppema, S. and Herrmann, F. (1997) Hodgkin's disease: a tumor with disturbed immunological pathways. Immunol Today, 18, 156-163.
9. Angiolillo, A.L., Sgadari, C., Taub, D.D., Liao, F., Farber, J.M., Maheshwari, S., Kleinman, H.K., Reaman, G.H. and Tosato, G. (1995) Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo. J Exp Med, 182, 155-162.
10. Sgadari, C., Angiolillo, A.L., Cherney, B.W., Pike, S.E., Farber, J.M., Koniaris, L.G., Vanguri, P., Burd, P.R., Sheikh, N., Gupta, G., Teruya-Feldstein, J. and Tosato, G. (1996) Interferon-inducible protein-10 identified as a mediator of tumor necrosis in vivo. Proc Natl Acad Sci U S A, 93, 13791-13796.
11. Sgadari, C., Farber, J.M., Angiolillo, A.L., Liao, F., Teruya-Feldstein, J., Burd, P.R., Yao, L., Gupta, G., Kanegane, C. and Tosato, G. (1997) Mig, the monokine induced by interferon-gamma, promotes tumor necrosis in vivo. Blood, 89, 2635-2643.
12. Teruya-Feldstein, J., Jaffe, E.S., Burd, P.R., Kanegane, H., Kingma, D.W., Wilson, W. H., Longo, D.L. and Tosato, G. (1997) The role of Mig, the monokine induced by interferon-gamma, and IP-10, the interferon-gamma-inducible protein-10, in tissue necrosis and vascular damage associated with Epstein-Barr virus-positive lymphoproliferative disease. Blood, 90, 4099-4105.
13. Setsuda, J., Teruya-Feldstein, J., Harris, N.L., Ferry, J.A., Sorbara, L., Gupta, G., Jaffe, E.S. and Tosato, G. (1999) Interleukin-18, interferon-gamma. IP-10. and Mig expression in Epstein-Barr virus-induced infectious mononucleosis and posttransplant lymphoproliferative disease. Am J Pathol, 155, 257-265.
14. Luciani, M.G., Stoppacciaro, A., Peri, G., Mantovani, A. and Ruco, L.P. (1998) The monocyte chemolactic protein a (MCP-1) and interleukin 8 (IL-8) in Hodgkin's disease and in solid tumours. Mol Pathol, 51, 273-276.
15. van den Berg, A., Visser, L. and Poppema, S. (1999) High expression of the CC chemokine TARC in Reed-Sternberg cells. A possible explanation tor the characteristic T-cell infiltratein Hodgkin's lymphoma. Am J Pathol, 154, 1685-1691.
16. Kapp, U., Yeh, W.C., Patterson, B., Elia, A.J., Kagi, D., Ho, A., Hessel, A., Tipsword, M., Williams, A., Mirtsos, C., Itie, A., Moyle, M. and Mak, T.W. (1999) Interleukin 13 is secreted by and stimulates the growth of Hodgkin and Reed-Sternberg cells. J Exp Med, 189, 1939-1946.
17. Kingma, D.W., Weiss, W.B., Jaffe, E.S., Kumar, S., Frekko, K. and Raffeld, M. (1996) Epstein-Barr virus latent membrane protein-1 oncogene deletions: correlations with malignancy in Epstein-Barr virus-associated lymphoproliferative disorders and malignant lymphomas. Blood, 88, 242-251.
18. Harris, N.L., Jaffe, E.S., Stein, H., Banks, P.M., Chan, J.K., Cleary, M.L., Delsol, G., De Wolf-Peeters, C., Falini, B. and Gatter, K.C. (1994) A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group [see comments]. Blood, 84, 1361-1392.
19. Harris, N.L. (1999) Hodgkin's lymphomas: classification, diagnosis, and grading [In Process Citation]. Semin Hematol, 36, 220-232.
20. Jaffe, E.S., Harris, N.L., Diebold, J. and Muller-Hermelink, H.K. (1999) World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues. A progress report. Am J Clin Pathol, 111, S8-12.
21. Jaffe, E.S. (1999) Hematopathology: integration of morphologic features and biologic markers for diagnosis. Mod Pathol, 12, 109-115.
22. Rudiger, T., Jaffe, E.S., Delsol, G., deWolf-Peeters, C., Gascoyne, R.D., Georgii, A., Harris, N.L., Kadin, M.E., MacLennan, K.A., Poppema, S., Stein, H., Weiss, L.E. and Muller-Hermelink, H.K. (1998) Workshop report on Hodgkin's disease and related diseases ("grey zone" lymphoma). Ann Oncol, 9, S31-38.
23. Hsu, S.M. and Hsu, P.L. (1990) Lack of effect of colony-stimulating factors, interleukins, interferons, and tumor necrosis factor on the growth and differentiation of cultured Reed-Sternberg cells. Comparison with effects of phorbol ester and retinoic acid. Am J Pathol, 136, 181-189.
24. Merz, H., Fliedner, A., Orscheschek, K., Binder, T., Sebald, W., Muller-Hermelink, H.K. and Feller, A.C. (1991) Cytokine expression in T-cell lymphomas and Hodgkin's disease. Its possible implication in autocrine or paracrine production as a potential basis for neoplastic growth. Am J Pathol, 139, 1173-1180.
25. Loetscher, M., Gerber, B., Loetscher, P., Jones, S.A., Piali, L., Cark-Lewis, I., Baggiolini, M. and Moser, B. (1996) Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes [see comments]. J Exp Med, 184, 963-969.
26. Liao, F., Rabin, R.L., Yannelli, J.R., Koniaris, L.G., Vanguri, P. and Farber, J.M. (1995) Human Mig chemokine: biochemical and functional characterization. J Exp Med, 182, 1301-1314.
27. Morente, M.M., Piris, M.A., Abraira, V., Acevedo, A., Aguilera, B., Bellas, C., Fraga, M., Garcia-Del-Moral, R., Gomez-Marcos, F., Menarguez, J., Oliva, H., Sanchez-Beato, M. and Montalban, C. (1997) Adverse clinical outcome in Hodgkin's disease is associated with loss of retinoblastoma protein expression, high Ki67 proliferation index, and absence of Epstein-Barr virus-latent membrane protein 1 expression. Blood, 90, 2429-2436.
28. Kaplan, G., Luster, A.D., Hancock, G. and Cohn, Z.A. (1987) The expression of a gamma interferon-induced protein (IP-10) in delayed immune responses in human skin. J Exp Med, 166, 1098-1108.
29. Vanguri, P. and Farber, J.M. (1994) IFN and virus-inducible expression of an immediate early gene, crg-2/IP-10, and a delayed gene, I-A alpha in astrocytes and microglia. J Immunol, 152, 1411-1418.
30. Haluska, F.G., Brufsky, A.M. and Canellos, G.P. (1994) The cellular biology of the Reed-Sternberg cell [see comments]. Blood, 84, 1005-1019.
31. Klein, S., Jones, D.B. and Tesch, H. (1992) In vitro differentiation of a Hodgkin's disease derived cell line. Hematol Oncol, 10, 195-205.
32. Rothenberger, S., Bachmann, E., Berger, C., McQuain, C., Odermatt, B.F. and Knecht, H. (1997) Natural 30 base pair and 69 base pair deletion variants of the LMP1 oncogene do stimulate NF-kappaB-mediated transcription. Oncogene, 14, 2123-2126.
33. Devergne, O., Hatzivassiliou, E., Izumi, K.M., Kaye, K.M., Kleijnen, M.F., Kieff, E. and Mosialos, G. (1996) Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: role in NF-kappaB activation. Mol Cell Biol, 16, 7098-7108.
34. Huen, D.S., Henderson, S.A., Croom-Carter, D. and Rowe, M. (1995) The Epstein-Barr virus latent membrane protein-1 (LMP1) mediates activation of NF-kappa B and cell surface phenotype via two effector regions in its carboxy-terminal cytoplasmic domain. Oncogene, 10, 549-560.
35. Cherney, B.W., Sgadari, C., Kanegane, C., Wang, F. and Tosato, G. (1998) Expression of the Epstein-Barr virus protein LMP1 mediates tumor regression in vivo. Blood, 91, 2491-2500.
36. Dreschfeld, J. (1892) Clinical lecture on acute Hodgkin's disease. British Medical Journal, 1, 893.
37. Samoszuk, M. and Nansen, L. (1990) Detection of interleukin-5 messenger RNA in Reed-Sternberg cells of Hodgkin's disease with eosinophilia. Blood, 75, 13-16.
38. Rot, A., Krieger, M., Brunner, T., Bischoff, S.C., Schall, T.J. and Dahinden, C.A. (1992) RANTES and macrophage inflammatory protein 1 alpha induce the migration and activation of normal human eosinophil granulocytes. J Exp Med, 176, 1489-1495.
39. Pinto, A., Aldinucci, D., Gloghini, A., Zagonel, V., Degan, M., Improta, S., Juzbasic, S., Todesco, M., Perin, V., Gattei, V., Herrmann, F., Gruss, H.J. and Carbone, A. (1996) Human eosinophils express functional CD30 ligand and stimulate proliferation of a Hodgkin's disease cell line. Blood, 88, 3299-3305.
40. Wardlaw, A.J., Moqbel, R., Cromwell, O. and Kay, A.B. (1986) Platelet-activating factor. A potent chemotactic and chemokinetic factor for human eosinophils. J Clin Invest, 78, 1701-1706.
41. Rothenberg, M.E., Luster, A.D. and Leder, P. (1995) Murine eotaxin: an eosinophil chemoattractant inducible in endothelial cells and in interleukin 4-induced tumor suppression. Proc Natl Acad Sci U S A, 92, 8960-8964.
42. Rothenberg, M.E., Ownbey, R., Mehlhop, P.D., Loiselle, P.M., van de Rijn, M., Bonventre, J.V., Oettgen, H.C., Leder, P. and Luster, A.D. (1996) Eotaxin triggers eosinophil-selective chemotaxis and calcium flux via a distinct receptor and induces pulmonary eosinophilia in the presence of interleukin 5 in mice. Mol Med, 2, 334-348.
43. Garcia-Zepeda, E.A., Rothenberg, M.E., Ownbey, R.T., Celestin, J., Leder, P. and Luster, A.D. (1996) Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia. Nat Med, 2, 449-456.
44. Chen, J., Akyurek, L.M., Fellstrom, B., Hayry, P. and Paul, L.C. (1998) Eotaxin and capping protein in experimental vasculopathy. Am J Pathol, 153, 81-90.
45. Uguccioni, M., Loetscher, P., Forssmann, U., Dewald, B., Li, H., Lima, S.H., Li, Y., Kreider, B., Garotta, G., Thelen, M. and Baggiolini, M. (1996) Monocyte chemotactic protein 4 (MCP-4), a novel structural and functional analogue of MCP-3 and eotaxin. J Exp Med, 183, 2374-2384.
46. Patel, V.P., Kreider, B.L., Li, Y., Li, H., Leung, K., Salcedo, T., Nardelli, B., Pippalla, V., Gentz, S., Thotakura, R., Parmelee, D., Gentz, R. and Garotta, G. (1997) Molecular and functional characterization of two novel human C-C chemokines as inhibitors of two distinct classes of myeloid progenitors. J Exp Med, 185, 1163-1172.
47. Pardigol, A., Forssmann, U., Zucht, H.D., Loetscher, P., Schulz-Knappe, P., Baggiolini, M., Forssmann, W.G. and Magert, H.J. (1998) HCC-2, a human chemokine: gene structure, expression pattern, and biological activity. Proc Natl Acad Sci U S A, 95, 6308-6313.
48. Dunzendorfer, S., Schratzberger, P., Reinisch, N., Kahler, C.M. and Wiedermann, C.J. (1998) Secretoneurin, a novel neuropeptide, is a potent chemoattractant for human eosinophils. Blood, 91, 1527-1532.
49. Forssmann, U., Uguccioni, M., Loetscher, P., Dahinden, C.A., Langen, H., Thelen, M. and Baggiolini, M. (1997) Eotaxin-2, a novel CC chemokine that is selective for the chemokine receptor CCR3, and acts like eotaxin on human eosinophil and basophil leukocytes. J Exp Med, 185, 2171-2176.
50. Daugherty, B.L., Siciliano, S.J., DeMartino, J.A., Malkowitz, L., Sirotina, A. and Springer, M.S. (1996) Cloning, expression, and characterization of the human eosinophil eotaxin receptor. J Exp Med, 183, 2349-2354.
51. Ponath, P.D., Qin, S., Post, T.W., Wang, J., Wu, L., Gerard, N.P., Newman, W., Gerard, C. and Mackay, C.R. (1996) Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils [see comments]. J Exp Med, 183, 2437-2448.
52. Teixeira, M.M., Wells, T.N., Lukacs, N.W., Proudfoot, A.E., Kunkel, S.L., Williams, T.J. and Hellewell, P.G. (1997) Chemokine-induced eosinophil recruitment. Evidence of a role for endogenous eotaxin in an in vivo allergy model in mouse skin. J Clin Invest, 100, 1657-1666.
53. White, J.R., Imburgia, C., Dul, E., Appelbaum, E., O'Donnell, K., O'Shannessy, D.J., Brawner, M., Fornwald, J., Adamou, J., Elshourbagy, N.A., Kaiser, K., Foley, J.J., Schmidt, D. B., Johanson, K., Macphee, C., Moores, K., McNulty, D., Scott, G.F., Schleimer, R.P. and Sarau, H.M. (1997) Cloning and functional characterization of a novel human CC chemokine that hinds to the CCR3 receptor and activates human eosinophils. J Leukoc Biol, 62, 667-675.
54. Sallusto, F., Mackay, C.R. and Lanzavecchia, A. (1997) Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science, 277, 2005-2007.
55. Gerber, B.O., Zanni, M.P., Uguccioni, M., Loetscher, M., Mackay, C.R., Pichler, W.J., Yawalkar, N., Baggiolini, M. and Moser, B. (1997) Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils. Curr Biol, 7, 836-843.
56. Teruya-Feldstein, J., Jaffe, E.S., Berkowitz, J.R., Burd, P.R. and Tosato, G. (1997) Eotaxin-1, a Specific Chemoattractant for Eosinophils in Hodgkin's Disease. BLOOD, 90, 388a.
57. Jundt, F., Anagnostopoulos, I., Bommert, K., Emmerich, F., Muller, G., Foss, H.-D., Rover, H.-D., Stein, H. and Dorken, B. (1999) Hodgkin/Reed-Sternberg Cells Induce Fibroblasts to Secrete Eotaxin, a Potent Chemoattractant for T Cells and Eosinophils. BLOOD, 94, 2065-2071.
58. Enblad, G., Sundstrom, C. and Glimelius, B. (1993) Infiltration of eosinophils in Hodgkin's disease involved lymph nodes predicts prognosis. Hematol Oncol, 11, 187-193.
59. Toth, J., Dworak, O. and Sugar, J. (1977) Eosinophil predominance in Hodgkin's disease. Z Krebsforsch Klin Onkol Cancer Res Clin Oncol, 89, 107-111.
60. von Wasielewski, R., Seth, S., Franklin, J., Fischer, R., Hübner, K., Hansmann, M., Diehl, V. and Georgii, A. (1999) Tissue Eosinophilia correlates strongly with poor prognosis in nodular sclerosing Hodgkin's disease, allowing for known prognostic factors. Blood, In press.
61. Rodenburg, R.J., Brinkhuis, R.F., Peek, R., Westphal, J.R., Van Den Hoogen, F.H., van Venrooij, W.J. and van de Putte, L.B. (1998) Expression of macrophage-derived chemokine (MDC) mRNA in macrophages is enhanced by interleukin-1beta, tumor necrosis factor alpha, and lipopolysaccharide. J Leukoc Biol, 63, 606-611.
62. Godiska, R., Chantry, D., Raport, C.J., Sozzani, S., Allavena, P., Leviten, D., Mantovani, A. and Gray, P.W. (1997) Human macrophage-derived chemokine (MDC), a novel Chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells. J Exp Med, 185, 1595-1604.
63. Ghia, P., Schaniel, C., Rolink, A.G., Nadler, L.M. and Cardoso, A.A. (1999) Human macrophage-derived chemokine (MDC) is strongly expressed following activation of both normal and malignant precursor and mature B cells. Curr Top Microbiol Immunol, 246, 103-110.
64. Andrew, D.P., Chang, M.S., McNinch, J., Wathen, S.T., Rihanek, M., Tseng, J., Spellberg, J.P. and Elias, C.G., 3rd (1998) STCP-1 (MDC) CC chemokine acts specifically on chronically activated Th2 lymphocytes and is produced by monocytes on stimulation with Th2 cytokines IL-4 and IL-13. J Immunol, 161, 5027-5038.
65. Doucet, C., Brouty-Boye, D., Pottin-Clemenceau, C., Canonica, G.W., Jasmin, C. and Azzurone, B. (1998) Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma. J Clin Invest, 101, 2129-2139.
66. Angiolillo, A.L., Sgadari, C., Sheikh, N., Reaman, G.H. and Tosato, G. (1995) Regression of experimental human leukemias and solid tumors induced by Epstein-Barr virus-immortalized B cells. Leuk Lymphoma, 19, 267-276.
67. Rothenberg, M.E., MacLean, J.A., Pearlman, E., Luster, A.D. and Leder, P. (1997) Targeted disruption of the chemokine eotaxin partially reduces antigen-induced tissue eosinophilia. J Exp Med, 185, 785-790.
68. Rothenberg, M.E. (1998) Eosinophilia. N Engl J Med, 338, 1592-1600.