Hodgkin/Reed-Sternberg cells induce fibroblasts to secrete eotaxin, a potent chemoattractant for T cells and eosinophils

Blood

Volumn 94, Issue 6, 1999, Pages 2065-2071

  Jundt, Franziska ^a   Anagnostopoulos, Ioannis ^b   Bommert, Kurt ^b   Emmerich, Florian ^b   Müller, Gerd ^b   Foss, Hans Dieter ^b   Royer, Hans Dieter ^b   Stein, Harald ^b   Dörken, Bernd ^b  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BETA CHEMOKINE; EOTAXIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CHEMOTAXIS; COCULTURE; EOSINOPHIL; FIBROBLAST; HISTOPATHOLOGY; HODGKIN DISEASE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REED STERNBERG CELL; T LYMPHOCYTE; TUMOR CELL;

EID: 0033567914     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v94.6.2065.418k15_2065_2071     Document Type: Article

References (39)

1. Hsu SM, Waldron JW, Hsu PL, Hough AJ: Cytokines in malignant lymphomas. Hum Pathol 24:1040, 1993
2. Kaufmann D, Longo DL: Hodgkin's disease. Crit Rev Oncol Hematol 13:135, 1992
3. Jücker M, Abts H, Li W, Schindler R, Merz H, Gunther A, von Kalle C, Schaadt M, Diamantstein T, Feller AC: Expression of interleukin-6 and interleukin-6 receptor in Hodgkin's disease. Blood 77:2413, 1991
4. Hsu SM, Zhao X: Expression of interleukin-1 in Reed-Sternberg cells and neoplastic cells from the true histiocytic malignancies. Am J Pathol 125:221, 1986
5. Bargou RC, Mapara MY, Zugck C, Daniel PT, Pawlita M, Döhner H, Dörken B: Characterization of a novel Hodgkin cell line, HD-MyZ, with myelomonocytic features mimicking Hodgkin's disease in severe combined immunodeficient mice. J Exp Med 177:1257, 1993
6. Foss HD, Herbst H, Oelmann E, Samol J, Grebe M, Blankenstein T, Matthes J, Qin ZH, Falini B, Pileri S, Diamantstein T, Stein H: Lymphotoxin, tumor necrosis factor and interleukin-6 gene transcripts are present in Hodgkin and Reed-Sternberg cells of most Hodgkin's disease cases. Br J Haematol 84:627, 1993
7. Foss HD, Hummel M, Gottstein S, Ziemann K, Falini B, Herbst H, Stein H: Frequent expression of IL-7 gene transcripts in tumor cells of classical Hodgkin's disease. Am J Pathol 146:33, 1995
8. Major RH, Leger LH: Marked eosinophilia in Hodgkin's disease. JAMA 112:2601, 1939
9. Butterfield JH, Kephart GM, Banks PM, Gleich GJ: Extracellular deposition of eosinophil granule major basic protein in lymph nodes of patients with Hodgkin's disease. Blood 68:394, 1987
10. Haluska FG, Brufsky AM, Cannellos GP: The cellular biology of Reed-Sternberg cell. Blood 84:1005, 1994
11. Klein S, Jücker M, Diehl V, Tesch H: Production of multiple cytokines by Hodgkin's disease derived cell lines. Hematol Oncol 10:319, 1992
12. Drexler HG: Recent results on the biology of Hodgkin and Reed-Sternberg cells. Part 2 Continous cell lines. Leuk Lymphoma 9:1, 1993
13. Rothenberg ME: Eosinophilia. N Engl J Med 338:1592, 1998
14. Pinto A, Aldinucci D, Gloghini A, Zagonel V, Degan M, Perin V, Todesco M, De Iuliis A, Improta S, Sacco C, Gattei V, Gruss HJ, Carbone A: The role of eosinophils in the pathobiology of Hodgkin's disease. Ann Oncol 8:89, 1997
15. Pinto A, Aldinucci D, Gloghini A, Zagonel V, Degan M, Improta S, Juzbaxic S, Todesco M, Perin V, Gattei V, Herrmann F, Grass HJ, Carbone A: Human eosinophils express functional CD30 ligand and stimulate proliferation of a Hodgkin's disease cell line. Blood 88:3299, 1996
16. Samoszuk M: Eosinophils and human cancer. Histol Histophathol 12:807, 1997
17. Clodi K, Younes A: Reed-Sternberg cells and the TNF family of receptors/ligands. Leuk Lymphoma 27:195, 1997
18. Pincus SH, Ramesh KS, Wyler DJ: Eosinophils stimulate fibroblast DNA synthesis. Blood 70:572, 1987
19. 1. Blood 78:2702, 1991
20. Poppema S: Immunology of Hodgkin's disease. Clin Hematol 9:447, 1996
21. Sallusto F, Mackay CR, Lanzavecchia A: Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science 277:2005, 1997
22. Jose PJ, Griffiths-Johnson DA, Collins PD, Walsh DT, Moqbel R, Totty NF, Truong O, Hsuan JJ, Williams TJ: Eotaxin: A potent eosinophil chemoattractant cytokine detected in guinea-pig model of allergic airways inflammation. J Exp Med 179:881, 1994
23. Ponath PD, Yin S, Ringler DJ, Clark-Lewis I, Wang J, Kassam N, Smith H, Shi X, Gonzalo, JA, Newman W, Gutierrez-Ramos JC, Mackay CR: Cloning of the human eosinohil chemoattractant, eotaxin. J Clin Invest 97:604, 1996
24. Rothenberg ME, Ownbery R, Mehlhop PD, Loiselle PM, Vanderijn M, Bonventre JV, Oettgen HC, Leder P, Luster AD: Eotaxin triggers eosinophil-selective chemotaxis and calcium flux via a distinct receptor and induces pulmonary eosinophilia in the presence of interleukin 5 in mice. Mol Med 2:334, 1996
25. Heath H, Yin S, Rao P, Wu L, LaRosa G, Kassam N, Ponath PD, Mackay CR: Chemokine receptor usage by human eosinophils. J Clin Invest 99:178, 1997
26. Sallusto F, Lenig D, Mackay CR, Lanzavecchia A: Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med 187:875, 1998
27. Gerber BO, Zanni MP, Uguccioni M, Loetscher M, Mackay CR, Pichler WJ, Yawalkar N, Baggiolini M, Moser B: Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils. Curr Biol 7:836, 1997
28. Baggiolini M: Chemokines and leukocyte traffic. Nature 392: 565, 1998
29. Luster AD: Chemokines - Chemotactic cytokines that mediate inflammation. N Engl J Med 338:436, 1998
30. Crump MP, Rafarathnam K, Kim KS, Clark-Lewis I, Sykes BD: Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation. J Biol Chem 273:22471, 1998
31. Matthews AN, Friend DS, Zimmermann N, Sarafi MN, Luster AD, Pearlman E, Wert SE, Rothenberg ME: Eotaxin is required for the baseline level of tissue eosinophils. Proc Natl Acad Sci USA 95:6273, 1998
32. Uguccioni M, Mackay CR, Ochsenberger B, Loetscher P, Rhis S, LaRosa GJ, Rao P, Ponath PD, Baggiolini M, Dahinden CA: High expression of the chemokine receptor CCR3 in human blood basophils. J Clin Invest 100:1137, 1997
33. Ponath PD, Yin S, Post TW, Wang J, Wu L, Gerard NP, Newman W, Gerard C, Mackay CR: Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils. J Exp Med 183:2437, 1996
34. Daugherty BL, Siciliano SJ, DeMartino JA, Malkowitz L, Sirotina A, Springer MS: Cloning, expression, and characterization of the human eosinophil eotaxin receptor. J Exp Med 183:2349, 1996
35. Garcia-Zepeda EA, Rothenberg ME, Ownbey RT, Celestin J, Leder P, Luster AD: Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia. Nat Med 2:449, 1996
36. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156, 1987
37. Cordell JL, Falini B, Erber WN, Gosh A, Abdulaziz Z, MacDonald S, Pulford K, Stein H, Mason DY: Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J Histochem Cytochem 32:219, 1984
38. Bartels J, Schlüter C, Richter W, Noso N, Kulke R, Christophers E, Schröder JM: Human dermal fibroblasts express eotaxin: Molecular cloning, mRNA expression, and identification of eotaxin sequence variants. Biochem Biophys Res Commun 225:1045, 1996
39. Roers A, Montesinos-Rongen M, Hansmann ML, Rajewsky K, Küppers R: Amplification of TCRβ gene rearrangements from micromanipulated single cells: T cells rosetting around Hodgkin and Reed-Sternberg cells in Hodgkin's disease are polyclonal. Eur J Immunol 28:2424, 1998