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Most of work described in this report has been taken from five Ph.D. thesis presented at the University of Zaragoza: (a) Franco, S. 1994.
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All nitrones described in this report showed to have a Z configuration and they can be prepared by condensing the precursor aldehyde with N-benzyl hydroxylamine. See: Dondoni, A.; Franco, S.; Junquera, F.; Merchan, F.L.; Merino, P.; Tejero, T. Synth. Commun. 1994, 24, 2537.
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44
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84985553225
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In this Account we use the syn/anti nomenclature according to Masamune convention (See: Masamune, S.; Ali, S.A.; Snitman, D.L.; Garvey, D.S. Angew. Chem. Int. Ed. Engl. 1980, 19, 557 and Masamune, S.; Kaiho, T.; Garvey, D.S. J. Am. Chem. Soc. 1982, 104, 5521). Diastereoselectivities are indicated as diastereomeric ratios in the form of ds, as recommended for stereoselective reactions in which two isomers can be obtained. In addition the Re/Si nomenclature is used for the description of the topicity of the approach of reagent (nucleophile) and substrate (nitrone). For an excellent and comprehensive discussion on the terminology used in stereochemistry see: Helmchen, G. In Stereoselective Synthesis, Houben-Weyl; Helmchen, G.; Hoffmann, R.W.; Mulzer, J.; Schaumann, E., Eds.; Thieme: Stuttgart 1996; Vol. 1, p. 1.
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45
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33845555760
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In this Account we use the syn/anti nomenclature according to Masamune convention (See: Masamune, S.; Ali, S.A.; Snitman, D.L.; Garvey, D.S. Angew. Chem. Int. Ed. Engl. 1980, 19, 557 and Masamune, S.; Kaiho, T.; Garvey, D.S. J. Am. Chem. Soc. 1982, 104, 5521). Diastereoselectivities are indicated as diastereomeric ratios in the form of ds, as recommended for stereoselective reactions in which two isomers can be obtained. In addition the Re/Si nomenclature is used for the description of the topicity of the approach of reagent (nucleophile) and substrate (nitrone). For an excellent and comprehensive discussion on the terminology used in stereochemistry see: Helmchen, G. In Stereoselective Synthesis, Houben-Weyl; Helmchen, G.; Hoffmann, R.W.; Mulzer, J.; Schaumann, E., Eds.; Thieme: Stuttgart 1996; Vol. 1, p. 1.
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Houben-Weyl; Helmchen, G.; Hoffmann, R.W.; Mulzer, J.; Schaumann, E., Eds.; Thieme: Stuttgart
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In this Account we use the syn/anti nomenclature according to Masamune convention (See: Masamune, S.; Ali, S.A.; Snitman, D.L.; Garvey, D.S. Angew. Chem. Int. Ed. Engl. 1980, 19, 557 and Masamune, S.; Kaiho, T.; Garvey, D.S. J. Am. Chem. Soc. 1982, 104, 5521). Diastereoselectivities are indicated as diastereomeric ratios in the form of ds, as recommended for stereoselective reactions in which two isomers can be obtained. In addition the Re/Si nomenclature is used for the description of the topicity of the approach of reagent (nucleophile) and substrate (nitrone). For an excellent and comprehensive discussion on the terminology used in stereochemistry see: Helmchen, G. In Stereoselective Synthesis, Houben-Weyl; Helmchen, G.; Hoffmann, R.W.; Mulzer, J.; Schaumann, E., Eds.; Thieme: Stuttgart 1996; Vol. 1, p. 1.
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