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Volumn 39, Issue 9, 2000, Pages 1495-1513

Somato-synaptic variation of GABA(A) receptors in cultured murine cerebellar granule cells: Investigation of the role of the α6 subunit

Author keywords

Benzodiazepines; Cerebellum; GABA(A) receptors; Gene knockout; Granule cells; IPSC; Transgenic mice; Zinc

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; RECEPTOR SUBTYPE; RECEPTOR SUBUNIT; ZINC ION;

EID: 0034109449     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(00)00007-1     Document Type: Article
Times cited : (18)

References (77)
  • 2
    • 0028229248 scopus 로고
    • Differential effects of GABAergic ligands in mouse and rat hippocampal neurons
    • Aguayo L.G., Pancetti F.C., Klein R.L., Harris R.A. Differential effects of GABAergic ligands in mouse and rat hippocampal neurons. Brain Research. 647:1994;97-105.
    • (1994) Brain Research , vol.647 , pp. 97-105
    • Aguayo, L.G.1    Pancetti, F.C.2    Klein, R.L.3    Harris, R.A.4
  • 3
    • 0027340033 scopus 로고
    • A receptor subunits: Alpha 1 beta 1 and alpha 1 beta 1 gamma 2S subunits produce unique ion channels with dissimilar single-channel properties
    • A receptor subunits: alpha 1 beta 1 and alpha 1 beta 1 gamma 2S subunits produce unique ion channels with dissimilar single-channel properties. Journal of Neuroscience. 13:1993;1429-1440.
    • (1993) Journal of Neuroscience , vol.13 , pp. 1429-1440
    • Angelotti, T.P.1    MacDonald, R.L.2
  • 6
    • 0023162271 scopus 로고
    • Mechanism of anion permeation through channels gated by glycine and gamma-aminobutyric acid in mouse cultured spinal neurones
    • Bormann J., Hamill O.P., Sakmann B. Mechanism of anion permeation through channels gated by glycine and gamma-aminobutyric acid in mouse cultured spinal neurones. Journal of Physiology. 385:1987;243-286.
    • (1987) Journal of Physiology , vol.385 , pp. 243-286
    • Bormann, J.1    Hamill, O.P.2    Sakmann, B.3
  • 7
    • 0028036284 scopus 로고
    • Large amplitude variability of GABAergic IPSCs in melanotropes from Xenopus laevis: Evidence that quantal size differs between synapses
    • Borst J.G., Lodder J.C., Kits K.S. Large amplitude variability of GABAergic IPSCs in melanotropes from Xenopus laevis: evidence that quantal size differs between synapses. Journal of Neurophysiology. 71:1994;639-655.
    • (1994) Journal of Neurophysiology , vol.71 , pp. 639-655
    • Borst, J.G.1    Lodder, J.C.2    Kits, K.S.3
  • 10
    • 0017670692 scopus 로고
    • Chlordiazepoxide selectively augments GABA action in spinal cord cell cultures
    • Choi D.W., Farb D.H., Fischbach G.D. Chlordiazepoxide selectively augments GABA action in spinal cord cell cultures. Nature. 269:1977;342-344.
    • (1977) Nature , vol.269 , pp. 342-344
    • Choi, D.W.1    Farb, D.H.2    Fischbach, G.D.3
  • 11
    • 0021286765 scopus 로고
    • Inhibitory post-synaptic currents in rat hippocampal CA1 neurones
    • Collingridge G.L., Gage P.W., Robertson B. Inhibitory post-synaptic currents in rat hippocampal CA1 neurones. Journal of Physiology. 356:1984;551-564.
    • (1984) Journal of Physiology , vol.356 , pp. 551-564
    • Collingridge, G.L.1    Gage, P.W.2    Robertson, B.3
  • 14
    • 0028171397 scopus 로고
    • Molecular pharmacology of gamma-aminobutyric acid type A receptor agonists and partial agonists in oocytes injected with different alpha, beta, and gamma receptor subunit combinations
    • Ebert B., Wafford K.A., Whiting P.J., Krogsgaard L.P., Kemp J.A. Molecular pharmacology of gamma-aminobutyric acid type A receptor agonists and partial agonists in oocytes injected with different alpha, beta, and gamma receptor subunit combinations. Molecular Pharmacology. 46:1994;957-963.
    • (1994) Molecular Pharmacology , vol.46 , pp. 957-963
    • Ebert, B.1    Wafford, K.A.2    Whiting, P.J.3    Krogsgaard, L.P.4    Kemp, J.A.5
  • 15
    • 0028825692 scopus 로고
    • Variation in GABA mini amplitude is the consequence of variation in transmitter concentration
    • Frerking M., Borges S., Wilson M. Variation in GABA mini amplitude is the consequence of variation in transmitter concentration. Neuron. 15:1995;885-895.
    • (1995) Neuron , vol.15 , pp. 885-895
    • Frerking, M.1    Borges, S.2    Wilson, M.3
  • 16
    • 0029416984 scopus 로고
    • A receptor gating kinetics on the α-subunit isoform: Implications for structure-function relations and synaptic transmission
    • A receptor gating kinetics on the α-subunit isoform: implications for structure-function relations and synaptic transmission. Journal of Physiology. 489:1995;529-543.
    • (1995) Journal of Physiology , vol.489 , pp. 529-543
    • Gingrich, K.J.1    Roberts, W.A.2    Kass, R.S.3
  • 17
    • 0032008230 scopus 로고    scopus 로고
    • A receptors: An allosteric, state-dependent mechanism determined by the gamma-subunit
    • A receptors: an allosteric, state-dependent mechanism determined by the gamma-subunit. Journal of Physiology. 506:1998;609-625.
    • (1998) Journal of Physiology , vol.506 , pp. 609-625
    • Gingrich, K.J.1    Burkat, P.M.2
  • 18
    • 0028145336 scopus 로고
    • Phosphorylation factors control neurotransmitter and neuromodulator actions at the gamma-aminobutyric acid type A receptor
    • Gyenes M., Wang Q., Gibbs T.T., Farb D.H. Phosphorylation factors control neurotransmitter and neuromodulator actions at the gamma-aminobutyric acid type A receptor. Molecular Pharmacology. 46:1994;542-549.
    • (1994) Molecular Pharmacology , vol.46 , pp. 542-549
    • Gyenes, M.1    Wang, Q.2    Gibbs, T.T.3    Farb, D.H.4
  • 19
    • 0030024882 scopus 로고    scopus 로고
    • Cloning of cDNAs encoding the human γ-aminobutyric acid type A receptor α6 subunit and characterization of the pharmacology of α6-containing receptors
    • Hadingham K.L., Garret E.M., Wafford K.A., Bain C., Heavens R.P., Sirinathsinghji D.J.S., Whiting P.J. Cloning of cDNAs encoding the human γ-aminobutyric acid type A receptor α6 subunit and characterization of the pharmacology of α6-containing receptors. Molecular Pharmacology. 49:1996;253-259.
    • (1996) Molecular Pharmacology , vol.49 , pp. 253-259
    • Hadingham, K.L.1    Garret, E.M.2    Wafford, K.A.3    Bain, C.4    Heavens, R.P.5    Sirinathsinghji, D.J.S.6    Whiting, P.J.7
  • 20
    • 0020518747 scopus 로고
    • Activation of multiple-conductance state chloride channels in spinal neurones by glycine and GABA
    • Hamill O.P., Bormann J., Sakmann B. Activation of multiple-conductance state chloride channels in spinal neurones by glycine and GABA. Nature. 305:1983;805-808.
    • (1983) Nature , vol.305 , pp. 805-808
    • Hamill, O.P.1    Bormann, J.2    Sakmann, B.3
  • 21
    • 0030951251 scopus 로고    scopus 로고
    • Slow kinetics of miniature IPSCs during early postnatal development in granule cells of the dentate gyrus
    • Hollrigel G.S., Soltesz I. Slow kinetics of miniature IPSCs during early postnatal development in granule cells of the dentate gyrus. Journal of Neuroscience. 17:1997;5119-5128.
    • (1997) Journal of Neuroscience , vol.17 , pp. 5119-5128
    • Hollrigel, G.S.1    Soltesz, I.2
  • 25
    • 0030025395 scopus 로고    scopus 로고
    • The impact of receptor desensitization on fast synaptic transmission
    • Jones M.V., Westbrook G.L. The impact of receptor desensitization on fast synaptic transmission. Trends in Neuroscience. 19:1996;96-101.
    • (1996) Trends in Neuroscience , vol.19 , pp. 96-101
    • Jones, M.V.1    Westbrook, G.L.2
  • 26
    • 0030867840 scopus 로고    scopus 로고
    • Shaping of IPSCs by endogenous calcineurin activity
    • Jones M.V., Westbrook G.L. Shaping of IPSCs by endogenous calcineurin activity. Journal of Neuroscience. 17:1997;7626-7633.
    • (1997) Journal of Neuroscience , vol.17 , pp. 7626-7633
    • Jones, M.V.1    Westbrook, G.L.2
  • 27
    • 0029028314 scopus 로고
    • Whole-cell and single-channel currents activated by GABA and glycine in granule cells of the rat cerebellum
    • Kaneda M., Farrant M., Cull-Candy S.G. Whole-cell and single-channel currents activated by GABA and glycine in granule cells of the rat cerebellum. Journal of Physiology. 485:1995;419-435.
    • (1995) Journal of Physiology , vol.485 , pp. 419-435
    • Kaneda, M.1    Farrant, M.2    Cull-Candy, S.G.3
  • 31
    • 0026612362 scopus 로고
    • A receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum
    • A receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum. Journal of Neuroscience. 12:1992;1063-1076.
    • (1992) Journal of Neuroscience , vol.12 , pp. 1063-1076
    • Laurie, D.J.1    Seeburg, P.H.2    Wisden, W.3
  • 33
    • 0034018491 scopus 로고    scopus 로고
    • Tonic benzodiazepine sensitive GABAergic inhibition in cultured rodent cerebellar granule cells
    • Leao R., Mellor J.R., Randall A.D. Tonic benzodiazepine sensitive GABAergic inhibition in cultured rodent cerebellar granule cells. Neuropharmacology. 39:2000;990-1003.
    • (2000) Neuropharmacology , vol.39 , pp. 990-1003
    • Leao, R.1    Mellor, J.R.2    Randall, A.D.3
  • 34
    • 0025729461 scopus 로고
    • Noncompetitive inhibition of gamma-aminobutyric acid A channels by Zn
    • Legendre P., Westbrook G.L. Noncompetitive inhibition of gamma-aminobutyric acid A channels by Zn. Molecular Pharmacology. 39:1991;267-274.
    • (1991) Molecular Pharmacology , vol.39 , pp. 267-274
    • Legendre, P.1    Westbrook, G.L.2
  • 40
    • 0030828318 scopus 로고    scopus 로고
    • A receptors in cultured murine cerebellar granule cells
    • A receptors in cultured murine cerebellar granule cells. Journal of Physiology. 503:1997;353-369.
    • (1997) Journal of Physiology , vol.503 , pp. 353-369
    • Mellor, J.R.1    Randall, A.D.2
  • 41
    • 0032518720 scopus 로고    scopus 로고
    • Voltage-dependent deactivation and desensitization of GABA responses in cultured murine cerebellar granule cells
    • Mellor J.R., Randall A.D. Voltage-dependent deactivation and desensitization of GABA responses in cultured murine cerebellar granule cells. Journal of Physiology. 506:1998;377-390.
    • (1998) Journal of Physiology , vol.506 , pp. 377-390
    • Mellor, J.R.1    Randall, A.D.2
  • 44
    • 0025961741 scopus 로고
    • Single channels activated by high concentrations of GABA in superior cervical ganglion neurones of the rat
    • Newland C.F., Colquhoun D., Cull Candy S.G. Single channels activated by high concentrations of GABA in superior cervical ganglion neurones of the rat. Journal of Physiology. 432:1991;203-233.
    • (1991) Journal of Physiology , vol.432 , pp. 203-233
    • Newland, C.F.1    Colquhoun, D.2    Cull Candy, S.G.3
  • 46
    • 0030922803 scopus 로고    scopus 로고
    • A receptor number underlie variation in GABA mini amplitude
    • A receptor number underlie variation in GABA mini amplitude. Neuron. 19:1997;697-709.
    • (1997) Neuron , vol.19 , pp. 697-709
    • Nusser, Z.1    Cull-Candy, S.2    Farrant, M.3
  • 47
    • 0032008543 scopus 로고    scopus 로고
    • A receptors to synaptic and extrasynaptic membranes of cerebellar granule cells
    • A receptors to synaptic and extrasynaptic membranes of cerebellar granule cells. Journal of Neuroscience. 18:1998;1693-1703.
    • (1998) Journal of Neuroscience , vol.18 , pp. 1693-1703
    • Nusser, Z.1    Sieghart, W.2    Somogyi, P.3
  • 48
    • 0029670816 scopus 로고    scopus 로고
    • A receptor is concentrated in both inhibitory and excitatory synapses on cerebellar granule cells
    • A receptor is concentrated in both inhibitory and excitatory synapses on cerebellar granule cells. Journal of Neuroscience. 16:1996;103-114.
    • (1996) Journal of Neuroscience , vol.16 , pp. 103-114
    • Nusser, Z.1    Sieghart, W.2    Stephenson, A.3    Somogyi, P.4
  • 49
    • 0028136698 scopus 로고
    • Lasting potentiation of inhibition is associated with an increased number of gamma-aminobutyric acid type A receptors activated during miniature inhibitory postsynaptic currents
    • Otis T.S., DeKoninck Y., Mody I. Lasting potentiation of inhibition is associated with an increased number of gamma-aminobutyric acid type A receptors activated during miniature inhibitory postsynaptic currents. Proceedings of the National Academy of Sciences USA. 91:1994;7698-7702.
    • (1994) Proceedings of the National Academy of Sciences USA , vol.91 , pp. 7698-7702
    • Otis, T.S.1    Dekoninck, Y.2    Mody, I.3
  • 50
    • 0027399657 scopus 로고
    • A responses in rat hippocampus
    • A responses in rat hippocampus. Neuron. 10:1993;189-200.
    • (1993) Neuron , vol.10 , pp. 189-200
    • Pearce, R.A.1
  • 51
    • 0024423323 scopus 로고
    • A-benzodiazepine receptors produced in transfected cells
    • A-benzodiazepine receptors produced in transfected cells. Science. 245:1989;1389-1392.
    • (1989) Science , vol.245 , pp. 1389-1392
    • Pritchett, D.B.1    Luddens, H.2    Seeburg, P.H.3
  • 52
    • 0027054188 scopus 로고
    • Kinetic properties of alpha 1 beta 1 gamma-aminobutyric acidA receptor channels expressed in Chinese hamster ovary cells: Regulation by pentobarbital and picrotoxin
    • Porter N.M., Angelotti T.P., Twyman R.E., MacDonald R.L. Kinetic properties of alpha 1 beta 1 gamma-aminobutyric acidA receptor channels expressed in Chinese hamster ovary cells: regulation by pentobarbital and picrotoxin. Molecular Pharmacology. 42:1992;872-881.
    • (1992) Molecular Pharmacology , vol.42 , pp. 872-881
    • Porter, N.M.1    Angelotti, T.P.2    Twyman, R.E.3    MacDonald, R.L.4
  • 53
    • 0026063649 scopus 로고
    • Nonstationary fluctuation analysis and direct resolution of single channel currents at postsynaptic sites
    • Robinson H.P., Sahara Y., Kawai N. Nonstationary fluctuation analysis and direct resolution of single channel currents at postsynaptic sites. Biophysical Journal. 59:1991;295-304.
    • (1991) Biophysical Journal , vol.59 , pp. 295-304
    • Robinson, H.P.1    Sahara, Y.2    Kawai, N.3
  • 54
    • 0032055975 scopus 로고    scopus 로고
    • A receptors and glomerular geometry
    • A receptors and glomerular geometry. Neuron. 20:1998;783-795.
    • (1998) Neuron , vol.20 , pp. 783-795
    • Rossi, D.J.1    Hamann, M.2
  • 56
    • 0029967726 scopus 로고    scopus 로고
    • Properties of putative cerebellar gamma-aminobutyric acid A receptor isoforms
    • Saxena N.C., Macdonald R.L. Properties of putative cerebellar gamma-aminobutyric acid A receptor isoforms. Molecular Pharmacology. 49:1996;567-579.
    • (1996) Molecular Pharmacology , vol.49 , pp. 567-579
    • Saxena, N.C.1    MacDonald, R.L.2
  • 59
    • 0026598169 scopus 로고
    • A receptor complex in cultured rat neurones
    • A receptor complex in cultured rat neurones. Journal of Physiology. 447:1992;587-625.
    • (1992) Journal of Physiology , vol.447 , pp. 587-625
    • Smart, T.G.1
  • 61
    • 0019638379 scopus 로고
    • Diazepam and (-)-pentobarbital: Fluctuation analysis reveals different mechanisms for potentiation of γ-aminobutyric acid responses in cultured central neurons
    • Study R.E., Barker J.L. Diazepam and (-)-pentobarbital: fluctuation analysis reveals different mechanisms for potentiation of γ-aminobutyric acid responses in cultured central neurons. Proceedings of the National Academy of Science USA. 78:1981;7180-7184.
    • (1981) Proceedings of the National Academy of Science USA , vol.78 , pp. 7180-7184
    • Study, R.E.1    Barker, J.L.2
  • 64
    • 0027282156 scopus 로고
    • Estimated conductance of glutamate receptor channels activated during EPSCs at the cerebellar mossy fiber-granule cell synapse
    • Traynelis S.F., Silver R.A., Cull Candy S.G. Estimated conductance of glutamate receptor channels activated during EPSCs at the cerebellar mossy fiber-granule cell synapse. Neuron. 11:1993;279-289.
    • (1993) Neuron , vol.11 , pp. 279-289
    • Traynelis, S.F.1    Silver, R.A.2    Cull Candy, S.G.3
  • 65
    • 0028181651 scopus 로고
    • A/Benzodiazepine receptor α6 subunit mRNA in granule cells of the cerebellar cortex and cochlear nuclei: Expression in developing and mutant mice
    • A/Benzodiazepine receptor α6 subunit mRNA in granule cells of the cerebellar cortex and cochlear nuclei: expression in developing and mutant mice. Journal of Comparative Neurology. 339:1994;341-352.
    • (1994) Journal of Comparative Neurology , vol.339 , pp. 341-352
    • Varecka, L.1    Wu, C.-H.2    Rotter, A.3    Frostholm, A.4
  • 67
    • 0027328861 scopus 로고
    • Functional comparison of the role of gamma subunits in recombinant human gamma-aminobutyric acidA/benzodiazepine receptors
    • Wafford K.A., Bain C.J., Whiting P.J., Kemp J.A. Functional comparison of the role of gamma subunits in recombinant human gamma-aminobutyric acidA/benzodiazepine receptors. Molecular Pharmacology. 44:1993;437-442.
    • (1993) Molecular Pharmacology , vol.44 , pp. 437-442
    • Wafford, K.A.1    Bain, C.J.2    Whiting, P.J.3    Kemp, J.A.4
  • 68
    • 0030989766 scopus 로고    scopus 로고
    • A receptor-mediated currents in granule cells of postnatal rat cerebellum
    • A receptor-mediated currents in granule cells of postnatal rat cerebellum. European Journal of Neuroscience. 9:1997;533-548.
    • (1997) European Journal of Neuroscience , vol.9 , pp. 533-548
    • Wall, M.J.1    Usowicz, M.M.2
  • 69
    • 0026611896 scopus 로고
    • A receptors on dorsal root ganglion neurons freshly isolated from adult rats
    • A receptors on dorsal root ganglion neurons freshly isolated from adult rats. Brain Research. 585:1992;56-62.
    • (1992) Brain Research , vol.585 , pp. 56-62
    • White, G.1
  • 73
    • 0032007994 scopus 로고    scopus 로고
    • GABAA receptor-mediated currents in interneurones and pyramidal cells of rat visual cortex
    • Xiang X., Huguenard J.R., Prince D.A. GABAA receptor-mediated currents in interneurones and pyramidal cells of rat visual cortex. Journal of Physiology. 506:1998;715-730.
    • (1998) Journal of Physiology , vol.506 , pp. 715-730
    • Xiang, X.1    Huguenard, J.R.2    Prince, D.A.3
  • 74
    • 0026089456 scopus 로고
    • A physiological role for endogenous zinc in rat synaptic neurotransmission
    • Xie X.M., Smart T.G. A physiological role for endogenous zinc in rat synaptic neurotransmission. Nature. 349:1991;521-524.
    • (1991) Nature , vol.349 , pp. 521-524
    • Xie, X.M.1    Smart, T.G.2
  • 76
    • 0028173380 scopus 로고
    • Changes in gamma-aminobutyrate type A receptor subunit mRNAs, translation product expression, and receptor function during neuronal maturation in vitro
    • Zheng T.M., Zhu W.J., Puia G., Vicini S., Grayson D.R., Costa E., Caruncho H.J. Changes in gamma-aminobutyrate type A receptor subunit mRNAs, translation product expression, and receptor function during neuronal maturation in vitro. Proceedings of the National Academy of Science USA. 91:1994;10952-10956.
    • (1994) Proceedings of the National Academy of Science USA , vol.91 , pp. 10952-10956
    • Zheng, T.M.1    Zhu, W.J.2    Puia, G.3    Vicini, S.4    Grayson, D.R.5    Costa, E.6    Caruncho, H.J.7
  • 77
    • 0028970627 scopus 로고
    • NMDA-mediated modulation of gamma-aminobutyric acid type A receptor function in cerebellar granule neurons
    • Zhu W.J., Vicini S., Harris B.T., Grayson D.R. NMDA-mediated modulation of gamma-aminobutyric acid type A receptor function in cerebellar granule neurons. Journal of Neuroscience. 15:1995;7692-7701.
    • (1995) Journal of Neuroscience , vol.15 , pp. 7692-7701
    • Zhu, W.J.1    Vicini, S.2    Harris, B.T.3    Grayson, D.R.4


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