The deletion of 14 amino acids in the seventh transmembrane domain of a naturally occurring calcitonin receptor isoform alters ligand binding and selectively abolishes coupling to phospholipase C

Journal of Biological Chemistry

Volumn 271, Issue 49, 1996, Pages 31127-31134

  Shyu, Jia Fwu ^a   Inoue, Daisuke ^a   Baron, Roland ^a   Horne, William C ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CALCITONIN RECEPTOR; COMPLEMENTARY DNA; CYCLIC AMP; MESSENGER RNA; PHOSPHOLIPASE C;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; DNA LIBRARY; DNA SEQUENCE; GENE DELETION; GENE EXPRESSION; LIGAND BINDING; MOLECULAR CLONING; NONHUMAN; OSTEOCLAST; PRIORITY JOURNAL; RABBIT; RECEPTOR AFFINITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA PROCESSING; RNA TRANSCRIPTION; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING, COMPETITIVE; CELL LINE; CLONING, MOLECULAR; COS CELLS; CYCLIC AMP; HUMANS; MOLECULAR SEQUENCE DATA; OSTEOCLASTS; PHOSPHOLIPASE C; POLYMERASE CHAIN REACTION; PROTEIN CONFORMATION; RABBITS; RECEPTORS, CALCITONIN; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TISSUE DISTRIBUTION;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0029958037     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.49.31127     Document Type: Article

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