Loss of cyclosporin and azidopine binding are associated with altered ATPase activity by a mutant P-glycoprotein with deleted Phe335

Molecular Pharmacology

Volumn 57, Issue 4, 2000, Pages 769-777

  Chen, G Kevin ^a   Lacayo, Norman J ^a   Durán, George E ^a   Cohen, Dalia ^b   Sikic, Branimir I ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); AZIDOPINE; CYCLOSPORIN; DACTINOMYCIN; DAUNORUBICIN; DRUG; GLYCOPROTEIN P; VALSPODAR; VERAPAMIL; VINBLASTINE;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG BINDING; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PRIORITY JOURNAL;

EID: 0034079788     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.57.4.769     Document Type: Article

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