Links between pharmacological properties of retinoids and nuclear retinoid receptors

International Journal of Cancer

Volumn 70, Issue 4, 1997, Pages 470-472

  Bollag, W ^a   Isnardi, L ^b   Jablonska, S ^c   Klaus, M ^a   Majewski, S ^c   Pirson, W ^a   Toma, S ^b  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b UNIVERSITY OF GENOA   (Italy)

^c MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

4 [(5,6,7,8 TETRAHYDRO 5,5,8,8 TETRAMETHYL 2 NAPHTHYL)CARBOXAMIDO]BENZOIC ACID; ISOTRETINOIN; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID; RETINOID RECEPTOR; RO 26 4456; RO 44 4753; RO 48 2249; UNCLASSIFIED DRUG;

ANGIOGENESIS; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL NUCLEUS; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TUMOR CELL LINE;

APOPTOSIS; BENZOATES; CELL DIFFERENTIATION; CELL DIVISION; CHROMANS; HL-60 CELLS; HUMANS; NEOVASCULARIZATION, PATHOLOGIC; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; RETINOIDS; TRANSCRIPTION FACTORS;

EID: 0031038058     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19970207)70:4<470::AID-IJC16>3.0.CO;2-J     Document Type: Article

References (12)

1. APFEL, C., BAUER, F., CRETTAZ, M., FORNI, L., KAMBER, M., KAUFMANN, F., LEMOTTE, P., PIRSON, W. and KLAUS, M., A retinoic acid receptor α antagonist selectively counteracts retinoic acid effects. Proc. Nat. Acad. Sci. (Wash.), 89, 7129-7133 (1992).
2. APFEL, C.M., KAMBER, M., KLAUS, M., MOHR, P., KEIDEL, S. and LEMOTTE, P.K., Enhancement of HL-60 differentiation by a new class of retinoids with selective activity on retinoid X receptor. J. Biol. Chem., 270, 30765-30772 (1995).
3. BOEHM, M.F., ZHANG, L., ZHI, L., MCCLURRG, M.R., BERGER, E., WAGONER, M., MAIS, D.E., SUTTO, C.M., DAVIES, P.J.A., HEYMAN, R.A. and NADZAN, A.M., Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells. J. Med. Chem., 38, 3146-3155 (1995).
4. BOLLAG, W., Retinoids and Interferon α in the prevention and treatment of preneoplastic and neoplastic diseases: a review. Retinoids Today Tomorrow. 40, 26-31 (1995).
5. BOLLAG, W., APFEL, C. and LEMOTTE, P., Retinoids: achievements, prospectives and future goals. In: S. Waxman (ed.), Differentiation therapy, pp. 285-302, Ares Serono Symposia Publications, Rome (1995).
6. DAWSON, M.I., CHAO, W.R., PINE, P., JONG, L., HOBBS, P.D., RUDD, C.K., QUICK, T.C., NILES, R.M., ZHANG, X.K., LOMBARDO, A., ELY, K.R., SHROOT, B. and FONTANA, J., Correlation of retinoid binding affinity to retinoic acid receptor α with retinoid inhibition of growth of estrogen receptor-positive MCF-7 mammary carcinoma cells. Cancer Res., 55, 4446-4451 (1995).
7. LIU, Y., LEE, M.O., WANG, H.G., LI, Y., HASHIMOTO, Y., KLAUS, M., REED, J.C. and ZHANG, X.K., Retinoic acid receptor β mediates the growth-inhibitory effect of retinoic acid by promoting apoptosis in human breast cancer cells. Mol. Cell. Biol., 16, 1138-1149 (1996).
8. 3 and their combination inhibit angiogenesis induced by non-HPV-harboring tumor cell lines. RARα mediates the antiangiogenic effect of retinoids. Cancer Lett., 89, 117-124 (1995).
9. ROMAN, S.D., CLARKE, C.L., HALL, R.E., ALEXANDER, I.E. and SUTHERLAND, R.L., Expression and regulation of retinoic acid receptors in human breast cancer cells. Cancer Res., 52, 2236-2242 (1992).
10. SCHUTT, A., ROSENBERGER, M., LOVEY, A., APFEL, C. and HSU, M.C., Receptor specificity in the antiproliferative response of breast carcinoma cell lines to retinoids. Proc. Amer. Assoc. Cancer Res., 37, 225 (1996).
11. SHEIKH, M.S., SHAG, Z.M., LI, X.S., DAWSON, M., JETTEN, A.M., WU, S., CONLEY, B.A., GARCIA, M., ROCHEFORT, H. and FONTANA, J.A., Retinoid resistant estrogen receptor-negative human breast carcinoma cells transfected with retinoic acid receptor-α acquire sensitivity to growth inhibition by retinoids. J. Biol. Chem., 269, 21440-21447 (1994).
12. ZHANG, L.X., MILLS, K.J., DAWSON, M.I., COLLINS, S.J. and JETTEN, A.M., Evidence for the involvement of retinoic acid receptor RARα-dependent signaling pathway in the induction of tissue transglutaminase and apoptosis by retinoids. J. Biol. Chem., 270, 6022-6029 (1995).