Leukocytes: Friend or foe

Intensive Care Medicine, Supplement

Volumn 26, Issue 1, 2000, Pages

  Bellingan, G ^a  

^a Rayne Institute ^*  (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CHEMOKINE; CYTOKINE; DEFENSIN; GELATINASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; NITRIC OXIDE; PEPTIDOGLYCAN; PROSTACYCLIN; PROSTAGLANDIN E2; SUPEROXIDE; TEICHOIC ACID; THROMBOPLASTIN; VASCULAR CELL ADHESION MOLECULE 1; CATHELICIDIN; ENDOTOXIN; FREE RADICAL; HISTATIN; LIPOPOLYSACCHARIDE; POLYPEPTIDE ANTIBIOTIC AGENT; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR;

ADULT RESPIRATORY DISTRESS SYNDROME; CONFERENCE PAPER; ENDOTHELIUM CELL; FIBROBLAST; GRAM NEGATIVE BACTERIUM; HUMAN; INFLAMMATION; INTENSIVE CARE; LEUKOCYTE; LEUKOCYTE ACTIVATION; MESOTHELIUM CELL; ARTICLE; DETOXIFICATION; INNATE IMMUNITY; LAVAGE; LEUKOCYTE FUNCTION; LEUKOPENIA; LIQUID; NONHUMAN; PATIENT; SEPSIS; SIGNAL TRANSDUCTION;

EID: 0034069260     PISSN: 09351701     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001340051127     Document Type: Conference Paper

References (67)

1. Adams DO, Hamilton TA (1992) Macrophages as destructive cells in host defence. In: Galin JI, Goldstein IM, Snyderman R (eds) Inflammation: basic principles and clinical correlates, 2nd edn. Raven, New York, pp 673-691
2. Gosling P (1998) The cellular immune and metabolic response to trauma. Crit Rev Clin Lab Sci 35: 59-112
3. Waxman K (1996) What mediates tissue injury after shock. New Horizons 4: 151-300
4. Dale MM, Foreman JC (1989 Introduction to the immunobiology and pathology of host defence mechanisms. In: Dale MM, Foreman JC (eds) Textbook of immunopharmacology. Blackwell, Oxford, pp 1-86
5. Davidson JM (1992) Wound repair. In: Galin JI, Goldstein IM, Snyderman R (eds) Inflammation: basic principles and clinical correlates, 2nd edn. Raven, New York, pp 809-819
6. Bone RC (1992) American college of chest physicians/Society for critical care medicine consensus conference. Definitions for sepsis, organ failure and guide-lines for the use of innovative therapies in sepsis. Chest 101: 1644-1655
7. Bone RC (1996) Sir Isaac Newton, sepsis, SIRS and CARS. Crit Care Med 24: 1125-1128
8. Bion JF (1999) Multiple organ failure. In Webb AR, Shapiro MJ, Singer M, Suter P (eds) Oxford textbook of critical care. Oxford University Press, Oxford, pp 923-926
9. Bellingan GJ (1999) Inflammatory cell activation in sepsis. British Medical Bulletin 55: 12-29
10. Docke W-D, Randow F. Syrbe U, Krausch D, Asadullah K, Reinke P, Volk H-D, Kox W (1997) Monocyte deactivation in septic patients: restoration by IFN-γ treatment. Nature Medicine 3: 678-681
11. Brun-Buisson C, Doyon F, Carlet J, Dellamonica P, Gouin F, Lepoutre A, Mercier JC, Offenstadt G, Regnier B (1995) Incidence, risk factors, and outcome of severe sepsis and septic shock in adults. A multicenter prospective study in intensive care units. French ICU Group for Severe Sepsis. JAMA 274: 968-974
12. Vincent JL, Bihari DJ, Suter PM, Bruining HA, White J, Nicolas-Chanoin MH, Wolff M, Spencer RC, Hemmer M (1995) The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee. JAMA 274: 639-644
13. Condliffe AM, Kitchen E, Chilvers ER (1998) Neutrophil priming: pathophysiological consequences and underlying mechanisms. Clin Sci 94: 461-471
14. Abraham E (1996) Alterations in transcriptional regulation of inflammatory and immunoregulatory cytokine expression by hemorrhage, injury and critical illness. New Horiz 4: 184-193
15. Phan SH, Gharaee-Kermani M, McGarry B, Kunkel SL, Wolber FW (1992) Regulation of rat pulmonary artery endothelial cell transforming growth factor-beta production by IL-1 beta and tumor necrosis factor-alpha. J Immunol 149: 103-6
16. Topley N, Liberek T, Davenport A, Li FK, Fear H, Williams JD (1996) Activation of inflammation and leukocyte recruitment into the peritoneal cavity. Kidney Int Suppl 56:S17-S21
17. Sugarman BJ, Aggarwal BB, Hass PE, Figari IS, Palladino MA Jr. Shepard HM (1985) Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro. Science 230: 943-5
18. Jung U, Ramos CL, Bullard DC, Ley K (1998) Gene targeted mice reveal importance of L-selectin-dependent rolling for neutrophil adhesion. Am J Physiol 274: 1785-1791
19. Ley K (1996) Molecular mechanisms of leukocyte recruitment in the inflammatory process Cardiovasc Res 32: 733-742
20. Albelda SM (1991) Endothelial and epithelial cell adhesion molecules. Am J Respir Cell Mol Biol 4: 195-203
21. Meerschart J, Furie MB (1995) The adhesion molecules used by monocytes for migration across endothelium include CD11a/CD18, CD11b/CD18 and VLA-4 on monocytes and ICAM-1, VCAM-1 and other ligands on endothelium. J Immunol 154: 4099-4112
22. Savill JS, Hogg N, Ren Y, Haslett C (1992) Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis. J Clin Invest 90: 1513-1522
23. Haslett C, Savill JS, Whyte MKB, Stern M, Dransfield I, Meagher LC (1994) Granulocyte apoptosis and the control of inflammation. Phil Trans R Soc Lond 345: 327-333
24. Bellingan GJ, Caldwell H, Howie SEM, Dransfield I, Haslett C (1996) In vivo fate of the inflammatory macrophage during the resolution of inflammation: inflammatory macrophages do not die locally but emigrate to the draining lymph nodes. J Immunol 157: 2577-2585
25. Glauser M (1998) Empiric therapy of bacterial infections in patients with severe neutropenia. Diagn Microbiol Infect Dis 31: 467-72
26. 2 integrins. J Clin Invest 100: 1725-1733
27. Segal AW (1996) The NADPH oxidase and chronic granulomatous disease. Mol Med Today 2: 129-135
28. Remick D, Manohar P, Bolgos G, Rodriguez J, Moldawer L, Wollenberg G (1995) Blockade of tumor necrosis factor reduces lipopolysaccharide lethality, but not the lethality of cecal ligation and puncture. Shock 4: 89-95
29. Pfeffer K, Matsuyama T, Kundig TM, Wakeham A, Kishihara K, Shahinian A, Wiegmann K, Ohashi PS, Kronke M, Mak TW (1993) Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 73: 457-467
30. Netea MG, Blok WL, Kullberg BJ, Bemelmans M, Vogels MT, Buurman WA, van der Meer JW (1995) Pharmacologic inhibitors of tumor necrosis factor production exert differential effects in lethal endotoxemia and in infection with live microorganisms in mice. J Infect Dis 171: 393-399
31. Stevenson MM, Ghadirian E (1989) Human recombinant tumor necrosis factor alpha protects susceptible A/J mice against lethal Plasmodium chabaudi AS infection. Infect Immun 57: 3936-3939
32. Garcia I, Miyazaki Y, Araki K, Araki M, Lucas R, Grau GE, Milon G, Belkaid Y, Montixi C, Lesslauer W et al. (1995) Transgenic mice expressing high levels of soluble TNF-R1 fusion protein are protected from lethal septic shock and cerebral malaria, and are highly sensitive to Listeria monocytogenes and Leishmania major infections. Eur J Immunol 25: 2401-2407
33. D'Souza MJ, Oettinger CW, Milton GV (1999) Evaluation of microspheres containing cytokine neutralizing antibodies in endotoxemia. Drug Dev Ind Pharm 25: 727-734
34. Burdack S, Schmidt A, Knieschies E, Rollinghoff M, Beuscher HU (1997) Tumor necrosis factor-alpha expression induced by anti-YopB antibodies coincides with protection against Yersinia enterocolitica infection in mice. Med Microbiol Immunol (Berl) 185: 223-229
35. Boland A, Cornelis GR (1998) Role of YopP in suppression of tumor necrosis factor alpha release by macrophages during Yersinia infection. Infect Immun 66: 1878-1884
36. Bellingan GJ (1999) Immune dysfunction associated with critical illness. In: Webb AR, Shapiro MJ, Singer M, Suter P (eds) Oxford textbook of critical care. Oxford University Press, Oxford, pp 898-902
37. Meakins JL, McLean AP, Kelly R, Bubenik O, Pietsch JB, MacLean LD (1978) Delayed hypersensitivity and neutrophil chemotaxis: effect of trauma. J Trauma 18: 240-247
38. McCarter MD, Mack VE, Daly JM, Naama HA, Galvano SE (1998) Trauma-induced alterations in macrophage function. Surgery 123: 96-101
39. Ayala A, Perrin MM, Ertel W, Chaudry IH (1992) Differential effects of hemorrhage on Kupffer cells: decreased antigen presentation despite increased inflammatory cytokine (IL-1, IL-6 and TNF) release. Cytokine 4: 66-75
40. Nelson S, Belknap SM, Carlson RW, Dale D, DeBoisblanc B, Farkas S, Fotheringham N, Ho H, Marrie T, Movahhed H, Root R, Wilson J (1998) A randomized controlled trial of filgrastim as an adjunct to antibiotics for treatment of hospitalized patients with community-acquired pneumonia. CAP Study Group. J Infect Dis 178: 1075-1080
41. Lee SM, Radford JA, Dobson L, Huq T, Ryder WD, Pettengell R, Morgenstern GR, Scarffe JH, Crowther D (1998) Recombinant human granulocyte colony-stimulating factor (filgrastim) following high-dose chemotherapy and peripheral blood progenitor cell rescue in high-grade non-Hodgkin's lymphoma: clinical benefits at no extra cost. Br J Cancer 77: 1294-1299
42. Heil G, Hoelzer D, Sanz MA, Lechner K, Liu Yin JA, Papa G, Noens L, Szer J, Ganser A, O'Brien C, Matcham J, Barge A (1997) A randomized, double-blind, placebo-controlled, phase III study of filgrastim in remission induction and consolidation therapy for adults with de novo acute myeloid leukemia. The International Acute Myeloid Leukemia Study Group. Blood 90: 4710-4718
43. Tomas L (1974) The lives of a cell. Notes of a biology watcher. The Viking Press, New York
44. Lee CT, Fein AM, Lippmann M, Holtzman H, Kimbel P, Weinbaum G (1981) Elastolytic activity in pulmonary lavage fluid from patients with adult respiratory-distress syndrome. N Engl J Med 304: 192-196
45. Riva CM, Morganroth ML, Ljungman AG, Schoeneich SO, Marks RM, Todd RF 3d, Ward PA, Boxer LA (1990) Iloprost inhibits neutrophil-induced lung injury and neutrophil adherence to endothelial monolayers. Am J Respir Cell Mol Biol 3: 301-309
46. Heflin AC Jr, Brigham KL (1981) Prevention by granulocyte depletion of increased vascular permeability of sheep lung following endotoxemia. J Clin Invest 68: 1253-1260
47. Braude S, Apperley J, Krausz T, Goldman JM, Royston D (1985) Adult respiratory distress syndrome after allogeneic bone-marrow transplantation: evidence for a neutrophil-independent mechanism. Lancet 1: 1239-1242
48. Li FK, Davenport A, Robson RL, Loetscher P, Rothlein R, Williams JD, Topley N (1998) Leukocyte migration across human peritoneal mesothelial cells is dependent on directed chemokine secretion and ICAM-1 expression. Kidney Int 54: 2170-2183
49. Parks E, Lukacs NW, Stricter RM, Kunkel SL (1998) Chemokine expression in endothelial cells and monocytes is differentially regulated. Pathobiology 66: 64-70
50. Vancheri C, Ohtoshi T, Cox G, Xaubet A, Abrams JS, Gauldie J, Dolovich J, Denburg J, Jordana M (1991) Neutrophilic differentiation induced by human upper airway fibroblast-derived granulocyte/macrophage colony-stimulating factor (GM-CSF). Am J Respir Cell Mol Biol 4: 11-17
51. Madtes DK, Rubenfeld G, Klima LD, Milberg JA, Steinberg KP, Martin TR, Raghu G, Hudson LD, Clark JG (1998) Elevated transforming growth factor-alpha levels in bronchoalveolar lavage fluid of patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 158: 424-430
52. Wright SD, Ramos RA, Hermanowski-Vosatka A, Rockwell P, Detmers PA (1991) Activation of the adhesive capacity of CR3 on neutrophils by endotoxin: dependence on lipopolysaccharide binding protein and CD14. J Exp Med 173: 1281-2186
53. Ulevitch RJ, Tobias PS (1999) Recognition of gram-negative bacteria and endotoxin by the innate immune system. Curr Opin Immunol 11: 19-22
54. Medzhitov R, Janeway CA Jr (1997) Innate immunity: the virtues of a nonclonal system of recognition. Cell 91: 295-298
55. Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA (1996) The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86: 973-983
56. Kopp EB, Medzhitov R (1999) The Toll-receptor family and control of innate immunity. Curr Opin Immunol 11: 13-18
57. Medzhitov R, Preston-Hurlburt P, Janeway CA Jr (1997) A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388: 394-397
58. Yang RB, Mark MR, Gray A, Huang A, Xie MH, Zhang M, Goddard A, Wood WI, Gurney AL, Godowski PJ (1998) Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling. Nature 395: 284-288
59. Schumann RR, Lamping N, Hoess A (1997) Interchangeable endotoxin-binding domains in proteins with opposite lipopolysaccharide-dependent activities. J Immunol 159: 5599-5605
60. de Haas CJ, van der Zee R, Benaissa-Trouw B, van Kessel KP, Verhoef J, van Strijp JA (1999) Lipopolysaccharide (LPS)-binding synthetic peptides derived from serum amyloid P component neutralize LPS. Infect Immun 67: 2790-2796
61. Munford RS, Dietschy JM (1985) Effects of specific antibodies, hormones, and lipoproteins on bacterial lipopolysaccharides injected into the rat. J Infect Dis 152: 177-184
62. Tobias PS, Soldau K, Iovine NM, Elsbach P, Weiss J (1997) Lipopolysaccharide (LPS)-binding proteins BPI and LBP form different types of complexes with LPS. J Biol Chem 272: 18682-18685
63. Netea MG, Demacker PN, Kullberg BJ, Boerman OC, Verschueren I, Stalenhoef AF, van der Meer JW (1996) Low-density lipoprotein receptor-deficient mice are protected against lethal endotoxemia and severe gram-negative infections. J Clin Invest 97: 1366-1372
64. Parker TS, Levine DM, Chang JC, Laxer J, Coffin CC, Rubin AL (1995) Reconstituted high-density lipoprotein neutralizes gram-negative bacterial lipopolysaccharides in human whole blood. Infect Immun 63: 253-258
65. Netea MG, Demacker PN, Kullberg BJ, Jacobs LE, Verver-Jansen TJ, Boerman OC, Stalenhoef AF, Van der Meer JW (1998) Bacterial lipopolysaccharide binds and stimulates cytokine-producing cells before neutralization by endogenous lipoproteins can occur. Cytokine 10: 766-772
66. Lehrer RI, Ganz T (1999) Antimicrobial peptides in mammalian and insect host defence. Curr Opin Immunol 11: 23-27
67. Edgerton M, Koshlukova SE, Lo TE, Chrzan BG, Straubinger RM, Raj PA (1998) Candidacidal activity of salivary histatins. Identification of a histatin 5-binding protein on Candida albicans. J Biol Chem 273: 20438-20447