Lipopolysaccharide (LPS)-binding synthetic peptides derived from serum amyloid P component neutralize LPS

Infection and Immunity

Volumn 67, Issue 6, 1999, Pages 2790-2796

  De Haas, Carla J C ^a,b   Van Der Zee, Ruurd ^a   Benaissa Trouw, Barry ^a   Van Kessel, Kok P M ^a   Verhoef, Jan ^a   Van Strijp, Jos A G ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID P COMPONENT; BACTERIUM LIPOPOLYSACCHARIDE; DACTINOMYCIN; SYNTHETIC PEPTIDE;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERICIDAL ACTIVITY; GRAM NEGATIVE SEPSIS; HYDROPHOBICITY; LIGAND BINDING; MEMBRANE PERMEABILITY; MONOCYTE; MOUSE; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; SEPTIC SHOCK;

EID: 0032983238     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.67.6.2790-2796.1999     Document Type: Article

References (39)

1. Aoyama, H., D. Naka, Y. Yoshiyama, T. Ishii, J. Kondo, M. Mitsuka, and T. Hayase. 1997. Isolation and conformational analysis of fragment peptide corresponding to the heparin-binding site of hepatocyte growth factor. Biochemistry 36:10286-10291.
2. Bazil, V., M. Baudys, I. Hilgert, I. Stefanova, M. G. Low, J. Zbrozek, and V. Horejsi. 1989. Structural relationship between the soluble and membrane-bound forms of human monocyte surface glycoprotein CD14. Mol. Immunol. 26:657-662.
3. Bazil, V., V. Horejsi, M. Baudys, H. Kristofova, J. L. Strominger, W. Kostka, and I. Hilgert. 1986. Biochemical characterization of a soluble form of the 53-kDa monocyte surface antigen. Eur. J. Immunol. 16:1583-1589.
4. Bone, R. C. 1991. The pathogenesis of sepsis. Ann. Intern. Med. 115:457-469.
5. Botto, M., P. N. Hawkins, M. C. M. Bickerstaff, J. Herbert, A. E. Bygrave, A. McBride, W. L. Hutchinson, G. A. Tennent, M. J. Walport, and M. B. Pepys. 1997. Amyloid deposition is delayed in mice with targeted deletion of the serum amyloid P component gene. Nat. Med. 3:855-859.
6. Brackett, D. J., M. R. Lerner, M. A. Lacquement, R. He, and H. A. Pereira. 1997. A synthetic lipopolysaccharide-binding peptide based on the neutrophil-derived protein CAP37 prevents endotoxin-induced responses in conscious rats. Infect. Immun. 65:2803-2811.
7. Cardin, A. D., and H. J. R. Weintraub. 1989. Molecular modeling of protein-glycosaminoglycan interactions. Atherosclerosis 9:21-32.
8. de Haas, C. J. C., M. E. Van der Toi, K. P. M. Van Kessel, J. Verhoef, and J. A. G. Van Strijp. 1998. A synthetic lipopolysaccharide (LPS)-binding peptide based on amino acids 27-39 of serum amyloid P component inhibits LPS-induced responses in human blood. J. Immunol. 161:3607-3615.
9. Dhawan, S., R. L. Fields, and F. A. Robey. 1990. A novel peptide from amyloid P component supports cell attachment. Biochem. Biophys. Res. Commun. 171:1284-1290.
10. Elass Rochard, E., A. Roseanu, D. Legrand, M. Trif, V. Salmon, C. Motas, J. Montreuil, and G. Spik. 1995. Lactoferrin-lipopolysaccharide interaction: involvement of the 28-34 loop region of human lactoferrin in the high-affinity binding to Escherichia coli 055B5 lipopolysaccharide. Biochem. J. 312:839-845.
11. Elass-Rochard, E., D. Legrand, V. Salmon, A. Roseanu, M. Trif, P. S. Tobias, J. Mazurier, and G. Spik. 1998. Lactoferrin inhibits the endotoxin interaction with CD14 by competition with the lipopolysaccharide-binding protein. Infect. Immun. 66:486-491.
12. Emancipator, K., G. Csako, and R. J. Elin. 1992. In vitro inactivation of bacterial endotoxin by human lipoproteins and apolipoproteins. Infect. Immun. 60:596-601.
13. Emsley, J., H. E. White, B. P. O'Hara, G. Oliva, N. Srinivasan, I. J. Tickle, T. L. Blundell, M. B. Pepys, and S. P. Wood. 1994. Structure of pentameric human serum amyloid P component. Nature 367:338-345.
14. Garcia de Frutos, P., Y. Hardig, and B. Dahlback. 1995. Serum amyloid P component binding to C4b-binding protein. J. Biol. Chem. 270:26950-26955.
15. Gewurz, H., X. H. Zhang, and T. F. Lint. 1995. Structure and function of the pentraxins. Curr. Opin. Immunol. 7:54-64.
16. Gray, B. H., J. R. Haseman, and K. H. Mayo. 1995. B/PI-derived synthetic peptides: synergistic effects in tethered bactericidal and endotoxin neutralizing peptides. Biochim. Biophys. Acta 1244:185-190.
17. Haziot, A., B. Z. Tsuberi, and S. M. Goyert. 1993. Neutrophil CD14: biochemical properties and role in the secretion of tumor necrosis factor-alpha in response to lipopolysaccharide. J. Immunol. 150:5556-5565.
18. Heegaard, N. H., H. D. Mortensen, and P. Roepstorff. 1995. Demonstration of a heparin-binding site in serum amyloid P component using affinity capillary electrophoresis as an adjunct technique. J. Chromatogr. A 717:83-90.
19. Heegaard, N. H. H., P. M. H. Heegaard, P. Roepstorff, and F. A. Robey. 1996. Ligand-binding sites in human serum amyloid P component. Eur. J. Biochem. 239:850-856.
20. Hileman, R. E., J. R. Fromm, J. M. Weiler, and R. J. Linhardt. 1998. Glycosaminoglycan-protein interactions: definition of consensus sites in glycosaminoglycan binding proteins. Bioessays 20:156-167.
21. Hirata, M., Y. Shimomura, M. Yoshida, S. C. Wright, and J. W. Larrick. 1994. Endotoxin-binding synthetic peptides with endotoxin-neutralizing, antibacterial and anticoagulant activities. Prog. Clin. Biol. Res. 388:147-159.
22. Hoess, A., S. Watson, G. R. Siber, and R. Liddington. 1993. Crystal structure of an endotoxin-neutralizing protein from the horseshoe crab, Limulus anti-LPS factor, at 1.5 Å resolution. EMBO J. 12:3351-3356.
23. Hubacek, J. A., C. Büchler, C. Aslanidis, and G. Schmitz. 1997. The genomic organization of the genes for human lipopolysaccharide binding protein (LBP) and bactericidal permeability increasing protein (BPI) is highly conserved. Biochem. Biophys. Res. Commun. 236:427-430.
24. Janciauskiene, S., P. Garcia de Frutos. E. Carlemalm, B. Dahlback, and S. Eriksson. 1995. Inhibition of Alzheimer beta-peptide fibril formation by serum amyloid P component. J. Biol. Chem. 270:26041-26044.
25. Larrick, J. W., M. Hirata, H. Zheng, J. Zhong, D. Bolin, J. M. Cavaillon, H. S. Warren, and S. C. Wright. 1994. A novel granulocyte-derived peptide with lipopolysaccharide-neutralizing activity. J. Immunol. 152:231-240.
26. Little, R. G., D. N. Kelner, E. Lim, D. J. Burke, and P. J. Conlon. 1994. Functional domains of recombinant bactericidal/permeability increasing protein (rBPI23). J. Biol. Chem. 269:1865-1872.
27. Loveless, R. W., O. S. Floyd, J. G. Raynes, C. T. Yuen, and T. Feizi. 1992. Human serum amyloid P is a multispecific adhesive protein whose ligands include 6-phosphorylated mannose and the 3-sulphated saccharides galactose, N-acetylgalactosamine and glucuronic acid. EMBO J. 11:813-819.
28. Mann, D. M., E. Romm, and M. Migliorini. 1994. Delineation of the glycosaminoglycan-binding site in the human inflammatory response protein lactoferrin. J. Biol. Chem. 269:23661-23667.
29. Parker, T. S., D. M. Levine, J. C. Chang, J. Laxer, C. C. Coffin, and A. L. Rubin. 1995. Reconstituted high-density lipoprotein neutralizes gram-negative bacterial lipopolysaccharides in human whole blood. Infect. Immun. 63:253-258.
30. Pereira, H. A., I. Erdem, J. Pohl, and J. K. Spitznagel. 1993. Synthetic bactericidal peptide based on CAP37: a 37-kDa human neutrophil granule- associated cationic antimicrobial protein chemotactic for monocytes. Proc. Natl. Acad. Sci. USA 90:4733-4737.
31. Rasmussen, P. B., S. Bjorn, S. Hastrup, P. F. Nielsen, K. Norris, L. Thim, F. C. Wiberg, and H. Flodgaard. 1996. Characterization of recombinant human HBP/CAP37/azurocidin, a pleiotropic mediator of inflammation-enhancing LPS-induced cytokine release from monocytes. FEBS Lett. 390: 109-112.
32. Rensen, P. C., M. Oosten, E. Bilt, M. Eck, J. Kuiper, and T. J. Berkel. 1997. Human recombinant apolipoprotein E redirects lipopolysaccharide from Kupffer cells to liver parenchymal cells in rats in vivo. J. Clin. Investig. 99:2438-2445.
33. Steel, D. M., and A. S. Whitehead. 1994. The major acute phase reactants: C-reactive protein, serum amyloid P component and serum amyloid A protein. Immunol. Today 15:81-88.
34. Troelstra, A., P. Antal-Szalmas, L. A. M. de Graaf-Miltenburg, A. J. L. Weersink, J. Verhoef, K. P. M. Van Kessel, and J. A. G. Van Strijp. 1997. Saturable CD14-dependent binding of fluorescein-labeled lipopolysaccharide to human monocytes. Infect. Immun. 65:2272-2277.
35. Troelstra, A., B. N. G. Giepmans, K. P. M. Van Kessel, H. S. Lichenstein, J. Verhoef, and J. A. G. Van Strijp. 1997. Dual effects of soluble CD14 on LPS priming of neutrophils. J. Leukoc. Biol. 61:173-178.
36. 5 of human lactoferrin is essential for binding to heparin, bacterial lipopolysaccharide, human lysozyme and DNA. Biochem. J. 328:145-151.
37. Van der Zee, R., S. M. Anderton, C. A. F. Buskens. E. Alonso de Velasco, and W. Van Eden. 1995. Heat shock protein T cell epitopes as immunogenic carriers in subunit vaccines, p. 841-842. In H. L. S. Maya (ed.), Peptides 1994, proceedings of the Twenty-Third European Peptide Symposium. Escom Science Publishers B. V., Leiden, The Netherlands.
38. Wright, S. D., R. A. Ramos, A. Hermanowski Vosatka, P. Rockwell, and P. A. Detmers. 1991. Activation of the adhesive capacity of CR3 on neutrophils by endotoxin: dependence on lipopolysaccharide binding protein and CD14. J. Exp. Med. 173:1281-1286.
39. Wurfel, M. M., S. T. Kunitake, H. Lichenstein, J. P. Kane, and S. D. Wright 1994. Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS. J. Exp. Med. 180:1025-1035.