The thiazolidinedione insulin sensitiser, BRL 49653, increases the expression of PPAR-γ and aP2 in adipose tissue of high-fat-fed rats

Biochemical and Biophysical Research Communications

Volumn 229, Issue 3, 1996, Pages 752-757

  Pearson, S L ^a,c   Cawthorne, M A ^a   Clapham, J C ^b   Dunmore, S J ^a   Holmes, S D ^b   Moore, G B T ^b   Smith, S A ^b   Tadayyon, M ^b  

^a UNIVERSITY OF BUCKINGHAM   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c Clore Laboratory   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; LEPTIN; LIPID BINDING PROTEIN; MESSENGER RNA; PEROXISOME PROLIFERATOR; RECEPTOR; ROSIGLITAZONE; THIAZOLIDINE DERIVATIVE;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE DIET; CONTROLLED STUDY; EPIDIDYMIS FAT; GENE INDUCTION; LIPID DIET; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; RECEPTOR GENE;

EID: 0030600556     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1996.1876     Document Type: Article

References (23)

1. 1. Reaven, G. M. (1988) Diabetes 37, 1595-1607.
2. 2. DeFronzo, R. A., Bonadonna, R. C., and Ferannini, E. (1992) Diabetes Care 15, 318-368.
3. 3. Jeffcoat, R., Roberts, P. A., and James, A. T. (1979) Eur. J. Biochem. 101, 447-453.
4. 4. Storlien, L. H., Jenkins, A. B., Chisholm, D. J., Pascoe, W. S., Khori, S., and Kraegen, E. W. (1991) Diabetes 40, 280-289.
5. 5. Kahn, B. B., and Pederson, O. (1993) Endocrinology 132, 13-22.
6. 6. Fujiwara, T., Yoshioka, S., Yoshioka, T., Ushiyama, I., and Horikoshi, H. (1988) Diabetes 37, 1549-1558.
7. 7. Young, W. P., Cawthorne, M. A., Coyle, P. J., Holder, J. C., Holman, G. D., Kozka, I. J., Kirkham, D. M., Lister, C. A., and Smith, S. A. (1995) Diabetes 44, 1087-1092.
8. 8. Smith, S. A., Cawthorne, M. A., Coyle, P. J., Holder, J. C., Kirkham, D., Lister, C. A., Murphy, G. J., and Young, P. W. (1995) Diabetologia 36, (Supp 1) A184.
9. 9. Iwamoti, Y., Kuzuya, T., and Matsuda, A. (1991) Diabetes Care 14, 1083-1086.
10. 10. Oakes, N. D., Kennedy, C. J., Jenkins, A. B., Laybutt, D. R., Chisholm, D. J., and Kraegen, E. W. (1994) Diabetes 43, 1203-1210.
11. 11. Ibrahimi, A., Teboul, L., Gaillard, D., Amri, E-Z., Ailhaud, G., Young, P., Cawthorne, M. A., and Grimaldi, P. A. (1994) Mol. Pharmacol. 46, 1070-1076.
12. 12. Lehmann, J. M., Moore, L. B., Smith-Oliver, T. A., Wilkison, W. O., Willson, T. M., and Kliewer, S. A. (1995) J. Biol. Chem. 270, 12953-12956.
13. 13. Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., and Friedman, J. M. (1994) Nature 372, 425-432.
14. 14. Halaas, J. L., Gajiwala, K. S., Maffei, M., Cohen, S. L., Chait, B. T., Rabinowitz, D., Lallone, R. L., Burley, S. K., and Friedman, J. M. (1995) Science 269, 543-546.
15. 15. Scott, J. (1996) Nature 379, 113-114.
16. 16. Zhang, B., Graziano, M. P., Doebber, T. W., Leibowitz, M. D., White-Carrington, S., Szalkowski, D. M., Hey, P. J., Wu, M., Cullinan, C. A., Bailey, P., Lollmann, B., Frederich, R., Flier, J. S., Strader, C. D., and Smith, R. G. (1996) J. Biol. Chem. 271, 9455-9459.
17. 17. Chomcyznski, P., and Sacchi, N. (1987) Practical Biochemistry 162, 156-159.
18. 18. Lönnqvist, F., Arner, P., Nordfors, L., and Schalling, M. (1995) Nature Medicine 1, 950-956.
19. 19. Cusin, I., Sainsbury, A., Doyle, P., Rohner-Jeanrenaud, F., and Jeanrenaud, B. (1995) Diabetes 44, 1467-1470.
20. 20. Frederich, R. C., Hamann, A., Anderson, S., Lollmann, B., Lowell, B. B., and Flier, J. S. (1995) Nature Medicine 1, 1311-1314.
21. 21. Pelleymounter, M. A., Cullen, M. J., Baker, M. B., Hecht, R., Winters, D., Boone, T., and Collins, F. (1995) Science 269, 540-543.
22. 22. Kallen, C. B., and Lazar, M. A. (1996) Proc. Natl Acad. Sci. USA 93, 5793-5796.
23. 23. Kletzien, R. F., Foellmi, L. A., Harris, P. K. W., Wyse, B. M., and Clarke, S. D. (1992) Mol. Pharm. 42, 558-562.