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Volumn 10, Issue 13, 1999, Pages 2141-2151

Flt3 ligand antitumor activity in a murine breast cancer model: A comparison with granulocyte-macrophage colony-stimulating factor and a potential mechanism of action

Author keywords

[No Author keywords available]

Indexed keywords

FLT3 LIGAND; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; KANAMYCIN KINASE;

EID: 0033199589     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/10430349950017130     Document Type: Article
Times cited : (40)

References (54)
  • 1
    • 0030988168 scopus 로고    scopus 로고
    • Local inhibition of natural killer cell activity promotes the progressive growth of intraocular tumors
    • APTE, R.S., MAYHEW, E., and NIEDERKORN, J.Y. (1997). Local inhibition of natural killer cell activity promotes the progressive growth of intraocular tumors. Invest. Ophthalmol. Vis. Sci. 38, 1277-1282.
    • (1997) Invest. Ophthalmol. Vis. Sci. , vol.38 , pp. 1277-1282
    • Apte, R.S.1    Mayhew, E.2    Niederkorn, J.Y.3
  • 2
    • 0029685801 scopus 로고    scopus 로고
    • Therapeutic efficacy of T cells derived from lymph nodes draining a poorly immunogenic tumor transduced to secrete granulocyte-macrophage colony-stimulating factor
    • ARCA, M.J., KRAUSS, J.C., ARUGA, A., CAMERON, M.J., SHU, S., and CHANG, A.E. (1996a). Therapeutic efficacy of T cells derived from lymph nodes draining a poorly immunogenic tumor transduced to secrete granulocyte-macrophage colony-stimulating factor. Can. Gene Ther. 3, 39-47.
    • (1996) Can. Gene Ther. , vol.3 , pp. 39-47
    • Arca, M.J.1    Krauss, J.C.2    Aruga, A.3    Cameron, M.J.4    Shu, S.5    Chang, A.E.6
  • 3
    • 0030001007 scopus 로고    scopus 로고
    • Diverse manifestations of tumorigenicity and immunogenicity displayed by the poorly immunogenic B16-BL6 melanoma transduced with cytokine genes
    • ARCA, M.J., KRAUSS, J.C., STROME, S.E., CAMERON, M.J., and CHANG, A.E. (1996b). Diverse manifestations of tumorigenicity and immunogenicity displayed by the poorly immunogenic B16-BL6 melanoma transduced with cytokine genes. Cancer Immunol. Immunother. 42, 237-245.
    • (1996) Cancer Immunol. Immunother. , vol.42 , pp. 237-245
    • Arca, M.J.1    Krauss, J.C.2    Strome, S.E.3    Cameron, M.J.4    Chang, A.E.5
  • 4
    • 0029877716 scopus 로고    scopus 로고
    • Anti-tumor effects of granulocyte-macrophage colony-stimulating factor production by melanoma cells
    • ARMSTRONG, C.A., BOTELLA, R., GALLOWAY, T.H., MURRAY, N., KRAMP, J.M., SONG. I.S., and ANSEL, J.C. (1996). Anti-tumor effects of granulocyte-macrophage colony-stimulating factor production by melanoma cells. Cancer Res. 56, 2191-2198.
    • (1996) Cancer Res. , vol.56 , pp. 2191-2198
    • Armstrong, C.A.1    Botella, R.2    Galloway, T.H.3    Murray, N.4    Kramp, J.M.5    Song, I.S.6    Ansel, J.C.7
  • 5
    • 0025806563 scopus 로고
    • Murine tumor cells transduced with the gene for tumor necrosis factor-α: Evidence for paracrine immune effects of tumor necrosis factor against tumor
    • ASHER, A.L., MULE, J.J., KASID, A., RESTIFO, N.P., SALO, J.C., REICHERT, C.M., JAFFE, G., FENDLY, B., KRIEGLER, M., and ROSENBERG, S.A. (1991). Murine tumor cells transduced with the gene for tumor necrosis factor-α: Evidence for paracrine immune effects of tumor necrosis factor against tumor. J. Immunol. 146, 3327-3234.
    • (1991) J. Immunol. , vol.146 , pp. 3327-13234
    • Asher, A.L.1    Mule, J.J.2    Kasid, A.3    Restifo, N.P.4    Salo, J.C.5    Reichert, C.M.6    Jaffe, G.7    Fendly, B.8    Kriegler, M.9    Rosenberg, S.A.10
  • 6
    • 0028898598 scopus 로고
    • Major histocompatibility complex class II+ B7-1+ tumor cells are potent vaccines for stimulating tumor rejection in tumor-bearing mice
    • BASKAR, S., GLIMCHER, L., NABAVI, N., JONES, R.T., and OSTRANS-ROSENBERG, S. (1995). Major histocompatibility complex class II+ B7-1+ tumor cells are potent vaccines for stimulating tumor rejection in tumor-bearing mice. J. Exp. Med. 181, 619-629.
    • (1995) J. Exp. Med. , vol.181 , pp. 619-629
    • Baskar, S.1    Glimcher, L.2    Nabavi, N.3    Jones, R.T.4    Ostrans-Rosenberg, S.5
  • 7
    • 0029874990 scopus 로고    scopus 로고
    • Effective immunization against neuroblastoma using double-transduced tumor cells secreting GM-CSF and interferon-γ
    • BAUSERO, M.A., PANOSKALTSIS-MORTARI, A., BLAZAR, B.R., and KATSANIS, E. (1996). Effective immunization against neuroblastoma using double-transduced tumor cells secreting GM-CSF and interferon-γ. J. Immunother. 19, 113-124.
    • (1996) J. Immunother. , vol.19 , pp. 113-124
    • Bausero, M.A.1    Panoskaltsis-Mortari, A.2    Blazar, B.R.3    Katsanis, E.4
  • 8
    • 0030736703 scopus 로고    scopus 로고
    • Flt3 ligand synergizes with granulocyte-macrophage colony-stimulating factor or granulocyte colony-stimulating factor to mobilize hematopoietic progenitor cells into the peripheral blood of mice
    • BRASEL, K., McKENNA, H.J., CHARRIER, K., MORRISSEY, P.J., WILLIAMS, D.E., and LYMAN, S.D. (1997). Flt3 ligand synergizes with granulocyte-macrophage colony-stimulating factor or granulocyte colony-stimulating factor to mobilize hematopoietic progenitor cells into the peripheral blood of mice. Blood 90, 3781-3788.
    • (1997) Blood , vol.90 , pp. 3781-3788
    • Brasel, K.1    McKenna, H.J.2    Charrier, K.3    Morrissey, P.J.4    Williams, D.E.5    Lyman, S.D.6
  • 10
    • 0029151332 scopus 로고
    • Flt3 ligand stimulates/costimulates the growth of myeloid stem/progenitor cells
    • BROXMEYER, H.E., LU, L., COOPER, S., RUGGIERI, L., LI, Z.H., and LYMAN, S.D. (1995). Flt3 ligand stimulates/costimulates the growth of myeloid stem/progenitor cells. Exp. Hematol. 23, 1121-1129.
    • (1995) Exp. Hematol. , vol.23 , pp. 1121-1129
    • Broxmeyer, H.E.1    Lu, L.2    Cooper, S.3    Ruggieri, L.4    Li, Z.H.5    Lyman, S.D.6
  • 12
    • 0026034712 scopus 로고
    • Combined interleukin 1/interleukin 2 therapy of mice injected with highly metastatic Friend leukemia cells: Host antitumor mechanisms and marked effects on established metastases
    • CIOLLI, V., GABRIELE, L., SESTILI, P., VARANO, F., PROIETTI, E., GRESSER, I., TESTA, U., MONTESORO, E., BULGARINI, D., MARIANI, G., PESCHLE, C., and BELARDELLI, F. (1991). Combined interleukin 1/interleukin 2 therapy of mice injected with highly metastatic Friend leukemia cells: Host antitumor mechanisms and marked effects on established metastases. J. Exp. Med. 173, 313-322.
    • (1991) J. Exp. Med. , vol.173 , pp. 313-322
    • Ciolli, V.1    Gabriele, L.2    Sestili, P.3    Varano, F.4    Proietti, E.5    Gresser, I.6    Testa, U.7    Montesoro, E.8    Bulgarini, D.9    Mariani, G.10    Peschle, C.11    Belardelli, F.12
  • 13
    • 0031279151 scopus 로고    scopus 로고
    • In vivo administration of flt3 ligand markedly stimulates generation of dendritic cell progenitors from mouse liver
    • DRAKES, M.L., LU, L., SUBBOTIN, V.M., and THOMSON, A.W. (1997). In vivo administration of flt3 ligand markedly stimulates generation of dendritic cell progenitors from mouse liver. J. Immunol. 159, 4268-4278.
    • (1997) J. Immunol. , vol.159 , pp. 4268-4278
    • Drakes, M.L.1    Lu, L.2    Subbotin, V.M.3    Thomson, A.W.4
  • 14
    • 0027538181 scopus 로고
    • Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
    • DRANOFF, G., JAFFEE, E., LAZENBY, A., GOLUMBEK, P., LEVITSKY, H., BROSE, K., JACKSON, V., HAMADA, H., PARDOLL, D., and MULLIGAN, R.C. (1993). Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc. Natl. Acad. Sci. U.S.A. 90, 3539-3543.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 3539-3543
    • Dranoff, G.1    Jaffee, E.2    Lazenby, A.3    Golumbek, P.4    Levitsky, H.5    Brose, K.6    Jackson, V.7    Hamada, H.8    Pardoll, D.9    Mulligan, R.C.10
  • 15
    • 0031965021 scopus 로고    scopus 로고
    • Gene immunotherapy in murine acute myeloid leukemia: Granulocyte-macrophage colony-stimulating factor tumor cell vaccines elicit more potent anti-tumor immunity compared with B7 family and other cytokine vaccines
    • DUNUSSI-JOANNOPOULOS, K., DRANOFF, G., WEINSTEIN, H.J., FERRARA, J.L., BIERER, B.E., and CROOP, J.M. (1998). Gene immunotherapy in murine acute myeloid leukemia: Granulocyte-macrophage colony-stimulating factor tumor cell vaccines elicit more potent anti-tumor immunity compared with B7 family and other cytokine vaccines. Blood 91, 222-230.
    • (1998) Blood , vol.91 , pp. 222-230
    • Dunussi-Joannopoulos, K.1    Dranoff, G.2    Weinstein, H.J.3    Ferrara, J.L.4    Bierer, B.E.5    Croop, J.M.6
  • 17
    • 0032005228 scopus 로고    scopus 로고
    • FLT3 ligand administration inhibits tumor growth in murine melanoma and lymphoma
    • ESCHE, C., SUBBOTIN, V.M., MALISZEWSKI, C., LOTZE, M.T., and SHURIN, M.R. (1998). FLT3 ligand administration inhibits tumor growth in murine melanoma and lymphoma. Cancer Res. 58, 380-383.
    • (1998) Cancer Res. , vol.58 , pp. 380-383
    • Esche, C.1    Subbotin, V.M.2    Maliszewski, C.3    Lotze, M.T.4    Shurin, M.R.5
  • 20
    • 24244433490 scopus 로고    scopus 로고
    • Hematopoietic stem cell transduced with neomycin resistance gene-expressing retroviral vectors are not preferentially eliminated in vivo: Direct comparison with nonexpressing vectors in rhesus monkeys
    • Abstract
    • HANAZONO, Y., TISDALE, J., HEIM, D., WU, T., SELLERS, S., AGRICOLA, B., DONAHUE, R., and DUNBAR, C. (1998). Hematopoietic stem cell transduced with neomycin resistance gene-expressing retroviral vectors are not preferentially eliminated in vivo: Direct comparison with nonexpressing vectors in rhesus monkeys. Am. Soc. Gene Ther. 1, 87a. [Abstract]
    • (1998) Am. Soc. Gene Ther. , vol.1
    • Hanazono, Y.1    Tisdale, J.2    Heim, D.3    Wu, T.4    Sellers, S.5    Agricola, B.6    Donahue, R.7    Dunbar, C.8
  • 21
    • 0345510947 scopus 로고    scopus 로고
    • In vivo persistence of rhesus monkey lymphocytes transduced with a non-expressing retroviral vector compared to rapid clearance of lymphocytes transduced with a neo-expressing vector
    • Abstract
    • HEIM, D., HANAZONO, Y., METZGER, M., DONAHUE, R., and DUNBAR, C. (1998). In vivo persistence of rhesus monkey lymphocytes transduced with a non-expressing retroviral vector compared to rapid clearance of lymphocytes transduced with a neo-expressing vector. Am. Soc. Gene Ther. 1, 98a. [Abstract]
    • (1998) Am. Soc. Gene Ther. , vol.1
    • Heim, D.1    Hanazono, Y.2    Metzger, M.3    Donahue, R.4    Dunbar, C.5
  • 23
    • 0028952954 scopus 로고
    • The flt3 ligand supports proliferation of lymphohematopoietic progenitors and early B-lymphoid progenitors
    • HIRAYAMA, F., LYMAN, S.D., CLARK, S.C., and OGAWA, M. (1995). The flt3 ligand supports proliferation of lymphohematopoietic progenitors and early B-lymphoid progenitors. Blood 85, 1762-1768.
    • (1995) Blood , vol.85 , pp. 1762-1768
    • Hirayama, F.1    Lyman, S.D.2    Clark, S.C.3    Ogawa, M.4
  • 24
    • 0026694642 scopus 로고
    • Immunotherapy of mammary adenocarcinoma metastases in C3H/HeN mice with chronic administration of cyclooxygenase inhibitors alone or in combination with IL-2
    • KHOO, N., CHAN, F., SAARLOOS, M., and LALA, P. (1992). Immunotherapy of mammary adenocarcinoma metastases in C3H/HeN mice with chronic administration of cyclooxygenase inhibitors alone or in combination with IL-2. Clin. Exp. Metastasis 10, 239-252.
    • (1992) Clin. Exp. Metastasis , vol.10 , pp. 239-252
    • Khoo, N.1    Chan, F.2    Saarloos, M.3    Lala, P.4
  • 25
    • 0031154377 scopus 로고    scopus 로고
    • Sensitizing T-lymphocytes for adoptive immunotherapy by vaccination with wild-type or cytokine gene-transduced melanoma
    • LIPSHY, K.A., KOSTUCHENKO, P.J., HAMAD, G.G., BLAND, C.E., BARRETT, S.K., and BEAR, H.D. (1997). Sensitizing T-lymphocytes for adoptive immunotherapy by vaccination with wild-type or cytokine gene-transduced melanoma. Ann. Surg. Oncol. 4, 334-341.
    • (1997) Ann. Surg. Oncol. , vol.4 , pp. 334-341
    • Lipshy, K.A.1    Kostuchenko, P.J.2    Hamad, G.G.3    Bland, C.E.4    Barrett, S.K.5    Bear, H.D.6
  • 26
    • 0028803283 scopus 로고
    • Plasma/serum levels of flt3 ligand are low in normal individuals and highly elevated in patients with Fanconi anemia and acquired aplastic anemia
    • LYMAN, S.D., SEABERG, M., HANNA, R., ZAPPONE, J., BRASEL, K., ABKOWITZ, J.L., PRCHAL, J.T., SCHULTZ, J.C., and SHAHIDI, N.T. (1995). Plasma/serum levels of flt3 ligand are low in normal individuals and highly elevated in patients with Fanconi anemia and acquired aplastic anemia. Blood 86, 4091-4096.
    • (1995) Blood , vol.86 , pp. 4091-4096
    • Lyman, S.D.1    Seaberg, M.2    Hanna, R.3    Zappone, J.4    Brasel, K.5    Abkowitz, J.L.6    Prchal, J.T.7    Schultz, J.C.8    Shahidi, N.T.9
  • 28
    • 0029661945 scopus 로고    scopus 로고
    • Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-mediated mice: Multiple dendritic cell subpopulations identified
    • MARASKOVSKY, E., BRASEL, K., TEEPE, M., ROUX, E.R., LYMAN, S.D., SHORTMAN, K., and McKENNA, H.J. (1996). Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-mediated mice: Multiple dendritic cell subpopulations identified. J. Exp. Med. 184, 1953-1962.
    • (1996) J. Exp. Med. , vol.184 , pp. 1953-1962
    • Maraskovsky, E.1    Brasel, K.2    Teepe, M.3    Roux, E.R.4    Lyman, S.D.5    Shortman, K.6    McKenna, H.J.7
  • 29
    • 0025804998 scopus 로고
    • Role of natural killer and T-cells in interferon induced inhibition of spontaneous metastases of the B16F10L murine melanoma
    • MARKOVIC, S.N., and MURASKO, D.M. (1991). Role of natural killer and T-cells in interferon induced inhibition of spontaneous metastases of the B16F10L murine melanoma. Cancer Res. 51(4), 11124-1128.
    • (1991) Cancer Res. , vol.51 , Issue.4 , pp. 11124-11128
    • Markovic, S.N.1    Murasko, D.M.2
  • 30
    • 0023871422 scopus 로고
    • A safe packaging line for gene transfer: Separating viral genes on two different plasmids
    • MARKOWITZ, D., GOFF, S., and BANK, A. (1988). A safe packaging line for gene transfer: Separating viral genes on two different plasmids. J. Virol. 62, 1120-1124.
    • (1988) J. Virol. , vol.62 , pp. 1120-1124
    • Markowitz, D.1    Goff, S.2    Bank, A.3
  • 33
    • 0022767368 scopus 로고
    • Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production
    • MILLER, A.D., and BUTTIMORE, C. (1986). Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production. Mol. Cell. Biol. 6, 2895.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 2895
    • Miller, A.D.1    Buttimore, C.2
  • 34
    • 0024460181 scopus 로고
    • Improved retroviral vectors for gene transfer and expression
    • MILLER, A.D., and ROSMAN, G.J. (1989). Improved retroviral vectors for gene transfer and expression. BioTechniques 7, 980-990.
    • (1989) BioTechniques , vol.7 , pp. 980-990
    • Miller, A.D.1    Rosman, G.J.2
  • 35
    • 0030029570 scopus 로고    scopus 로고
    • The FLK2/FLT3 ligand synergizes with interleukin-7 in promoting stromal-cell-independent expansion and differentiation of human fetal pro-B cells in vitro
    • NAMIKAWA, R., MUENCH, M.O., DE VRIES, J.E., and RONCAROLO, M.G. (1996). The FLK2/FLT3 ligand synergizes with interleukin-7 in promoting stromal-cell-independent expansion and differentiation of human fetal pro-B cells in vitro. Blood 87, 1881-1890.
    • (1996) Blood , vol.87 , pp. 1881-1890
    • Namikawa, R.1    Muench, M.O.2    De Vries, J.E.3    Roncarolo, M.G.4
  • 36
    • 0029008355 scopus 로고
    • GM-CSF induced internal autocrine induced proliferation occurs in a compartment outside of the endoplasmic reticulum
    • ORCHARD, P.J., McIVOR, R.S., SINGH, H.A., and BLAZAR, B.R. (1995). GM-CSF induced internal autocrine induced proliferation occurs in a compartment outside of the endoplasmic reticulum. Exp. Hematol. 23, 573-582.
    • (1995) Exp. Hematol. , vol.23 , pp. 573-582
    • Orchard, P.J.1    McIvor, R.S.2    Singh, H.A.3    Blazar, B.R.4
  • 37
    • 2642674449 scopus 로고    scopus 로고
    • IFN-gamma-inducing factor/IL-18 administration mediates IFN-gamma- and IL-12-independent antitumor effects
    • OSAKI, T., PÉRON, J.M., CAI, Q., OKAMURA, H., ROBBINS, P.D., KURIMOTO, M., LOTZE, M.T., and TAHARA, H. (1998). IFN-gamma-inducing factor/IL-18 administration mediates IFN-gamma- and IL-12-independent antitumor effects. J. Immunol. 160, 1742-1749.
    • (1998) J. Immunol. , vol.160 , pp. 1742-1749
    • Osaki, T.1    Péron, J.M.2    Cai, Q.3    Okamura, H.4    Robbins, P.D.5    Kurimoto, M.6    Lotze, M.T.7    Tahara, H.8
  • 38
    • 0030755511 scopus 로고    scopus 로고
    • In vivo effects of Flt3/Flk2 ligand on mobilization of hematopoietic progenitors in primates and potent synergistic enhancement with granulocyte colony-stimulating factor
    • PAPAYANNOPOULOU, T., NAKAMOTO, B., ANDREWS, R.G., LYMAN, S.D., and LEE, M.Y. (1997). In vivo effects of Flt3/Flk2 ligand on mobilization of hematopoietic progenitors in primates and potent synergistic enhancement with granulocyte colony-stimulating factor. Blood 90, 620-629.
    • (1997) Blood , vol.90 , pp. 620-629
    • Papayannopoulou, T.1    Nakamoto, B.2    Andrews, R.G.3    Lyman, S.D.4    Lee, M.Y.5
  • 41
    • 0028153727 scopus 로고
    • Augmentation of anti-tumor immunity by tumor cells transduced with a retroviral vector carrying the interleukin-2 and interferon-gamma cDNAs
    • ROSENTHAL, F.M., CRONIN, K., BANNERJI, R., GOLDE, D.W., and GANSBACHER, B. (1994). Augmentation of anti-tumor immunity by tumor cells transduced with a retroviral vector carrying the interleukin-2 and interferon-gamma cDNAs. Blood 83, 1289-1298.
    • (1994) Blood , vol.83 , pp. 1289-1298
    • Rosenthal, F.M.1    Cronin, K.2    Bannerji, R.3    Golde, D.W.4    Gansbacher, B.5
  • 42
    • 0031937948 scopus 로고    scopus 로고
    • The influence of interleukin (IL)-4, IL-13, and Flt3 ligand on human dendritic cell differentiation from cord blood CD34+ progenitor cells
    • ROSENZWAJG, M., CAMUS, S., GUIGON, M., and GLUCKMAN, J.C. (1998). The influence of interleukin (IL)-4, IL-13, and Flt3 ligand on human dendritic cell differentiation from cord blood CD34+ progenitor cells. Exp. Hematol. 26, 63-72.
    • (1998) Exp. Hematol. , vol.26 , pp. 63-72
    • Rosenzwajg, M.1    Camus, S.2    Guigon, M.3    Gluckman, J.C.4
  • 44
    • 0026498125 scopus 로고
    • Effects of cancer immunotherapy with indomethacin and interleukin-2 on murine hematopoietic stem cells
    • SAARLOOS, M., KHOO, N., and LALA, P. (1992). Effects of cancer immunotherapy with indomethacin and interleukin-2 on murine hematopoietic stem cells. Cancer Res. 52, 6452-6462.
    • (1992) Cancer Res. , vol.52 , pp. 6452-6462
    • Saarloos, M.1    Khoo, N.2    Lala, P.3
  • 45
    • 0028289244 scopus 로고
    • Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor α
    • SALLUSTO, F., and LANZAVECCHI, A. (1994). Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor α. J. Exp. Med. 179, 1109-1118.
    • (1994) J. Exp. Med. , vol.179 , pp. 1109-1118
    • Sallusto, F.1    Lanzavecchi, A.2
  • 46
    • 0030816873 scopus 로고    scopus 로고
    • Antimetastatic effect of NK1+ T cells on experimental haematogenous tumour metastases in the liver and lungs of mice
    • SEKI, S., HASHIMOTO, W., OGASAWARA, K., SATOH, M., WATANABE, H., HABU, Y., HIRAIDE, H., and TAKEDA, K. (1997). Antimetastatic effect of NK1+ T cells on experimental haematogenous tumour metastases in the liver and lungs of mice. Immunology 92, 561-566.
    • (1997) Immunology , vol.92 , pp. 561-566
    • Seki, S.1    Hashimoto, W.2    Ogasawara, K.3    Satoh, M.4    Watanabe, H.5    Habu, Y.6    Hiraide, H.7    Takeda, K.8
  • 47
    • 0030005639 scopus 로고    scopus 로고
    • Flt3 ligand induces proliferation of quiescent human bone marrow CD34+CD38- Cells and maintains progenitor cells in vitro
    • SHAH, A.J., SMOGORZEWSKA, E.M., HANNUM, C., and CROOKS, G.M. (1996). Flt3 ligand induces proliferation of quiescent human bone marrow CD34+CD38-cells and maintains progenitor cells in vitro. Blood 87, 3563-3570.
    • (1996) Blood , vol.87 , pp. 3563-3570
    • Shah, A.J.1    Smogorzewska, E.M.2    Hannum, C.3    Crooks, G.M.4
  • 48
    • 0032530754 scopus 로고    scopus 로고
    • Expansion of functional NK cells in multiple tissue compartments of mice treated with Flt3-ligand: Implications for anti-cancer and anti-viral therapy
    • SHAW, S.G., MAUNG, A.A., STEPTOE, R.J., THOMSON, A.W., and VUJANOVIC, N.L. (1998). Expansion of functional NK cells in multiple tissue compartments of mice treated with Flt3-ligand: Implications for anti-cancer and anti-viral therapy. J. Immunol. 161, 2817-2824.
    • (1998) J. Immunol. , vol.161 , pp. 2817-2824
    • Shaw, S.G.1    Maung, A.A.2    Steptoe, R.J.3    Thomson, A.W.4    Vujanovic, N.L.5
  • 50
    • 0032936207 scopus 로고    scopus 로고
    • Effects of IL-12 on human ovarian tumors engrafted into SCID mice
    • SILVER, D.F., HEMPLING, R.E., PIVER, M.S., and REPASKY, E.A. (1999). Effects of IL-12 on human ovarian tumors engrafted into SCID mice. Gynecol. Oncol. 72, 154-160.
    • (1999) Gynecol. Oncol. , vol.72 , pp. 154-160
    • Silver, D.F.1    Hempling, R.E.2    Piver, M.S.3    Repasky, E.A.4
  • 52
    • 0030761480 scopus 로고    scopus 로고
    • Flt3 ligand in cooperation with transforming growth factor-beta 1 potentiates in vitro development of Langerhans-type dendritic cells and allows single-cell dendritic cell cluster formation under serum-free conditions
    • STROBL, H., BELLO-FERNANDEZ, C., RIEDL, E., PICKL, W.F., MAJDIC, O., LYMAN, S.D., and KNAPP, W. (1997). Flt3 ligand in cooperation with transforming growth factor-beta 1 potentiates in vitro development of Langerhans-type dendritic cells and allows single-cell dendritic cell cluster formation under serum-free conditions. Blood 90, 1425-1434.
    • (1997) Blood , vol.90 , pp. 1425-1434
    • Strobl, H.1    Bello-Fernandez, C.2    Riedl, E.3    Pickl, W.F.4    Majdic, O.5    Lyman, S.D.6    Knapp, W.7
  • 53
    • 0030716243 scopus 로고    scopus 로고
    • Generation of lytic natural killer 1.1 +, Ly-49- Cells from multipotential murine bone marrow progenitors in a stroma-free culture: Definition of cytokine requirements and developmental intermediates
    • WILLIAMS, N.S., MOORE, T.A., SCHATZLE, J.D., PUZANOV, I.J., SIVAKUMAR, P.V., ZLOTNIK, A., BENNETT, M., and KUMAR, V. (1998). Generation of lytic natural killer 1.1 +, Ly-49-cells from multipotential murine bone marrow progenitors in a stroma-free culture: Definition of cytokine requirements and developmental intermediates. J. Exp. Med. 186, 1609-1614.
    • (1998) J. Exp. Med. , vol.186 , pp. 1609-1614
    • Williams, N.S.1    Moore, T.A.2    Schatzle, J.D.3    Puzanov, I.J.4    Sivakumar, P.V.5    Zlotnik, A.6    Bennett, M.7    Kumar, V.8
  • 54
    • 0030854533 scopus 로고    scopus 로고
    • Gene therapy for metastatic brain tumors by vaccination with granulocyte-macrophage colony-stimulating factor-transduced tumor cells
    • YU, J.S., BURWICK, J.A., DRANOFF, G., and BREAKEFIELD, X.O. (1997). Gene therapy for metastatic brain tumors by vaccination with granulocyte-macrophage colony-stimulating factor-transduced tumor cells. Hum. Gene Ther. 8, 1065-1072.
    • (1997) Hum. Gene Ther. , vol.8 , pp. 1065-1072
    • Yu, J.S.1    Burwick, J.A.2    Dranoff, G.3    Breakefield, X.O.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.