Subtherapeutic corticosteroids potentiate the ability of interleukin 10 to prevent chronic inflammation in rats

Gastroenterology

Volumn 115, Issue 4, 1998, Pages 856-865

  Herfarth, H H ^a   Bocker, U ^a   Janardhanam, R ^a   Sartor, R B ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; DEXAMETHASONE; RECOMBINANT INTERLEUKIN 10;

ANIMAL MODEL; ARTICLE; CHRONIC DISEASE; COLITIS; CORTICOSTEROID THERAPY; DRUG EFFECT; DRUG POTENTIATION; FEMALE; HUMAN; HUMAN CELL; IMMUNOMODULATION; INFLAMMATORY DISEASE; NONHUMAN; PRIORITY JOURNAL; RAT; STEROID THERAPY; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0031707727     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(98)70257-4     Document Type: Article

References (62)

1. RB Sartor Current concepts of the etiology and pathogenesis of ulcerative colitis and Crohn's disease Gastroenterol Clin North Am 24 1995 475 507
2. N Feldmann FM Brennan RN Maini Rheumatoid arthritis Cell 85 1996 307 310
3. R Tisch H McDevitt Insulin-dependent diabetes mellitus Cell 85 1996 291 297
4. L Steinman Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system Cell 85 1996 299 302
5. MF Neurath I Fuss B Kelsall E Stuber W Strober Antibodies to interleukin 12 abrogate established experimental colitis in mice J Exp Med 182 1995 1281 1290
6. M Röcken M Racke EM Shevach IL-4 induced immune deviation as antigen-specific therapy for inflammatory autoimmune disease Immunol Today 17 1996 225 231
7. C Bogdan C Nathan Modulation of macrophage function by transforming growth factor beta, interleukin-4, and interleukin-10 Ann N Y Acad Sci 685 1993 713 739
8. TR Mosmann Properties and functions of interleukin-10 Adv Immunol 56 1994 1 16
9. O Rott B Fleischer E Cash Interleukin-10 prevents experimental allergic encephalomyelitis in rats Eur J Immunol 24 1994 1434 1440
10. AJ Rongione AM Kusske K Kwan SW Ashley HA Reber DW McFadden Interleukin 10 reduces the severity of acute pancreatitis in rats Gastroenterology 112 1997 960 967
11. JL Van Laethem A Marchant A Delvaux M Goldman P Robberecht T Velu J Deviere Interleukin 10 prevents necrosis in murine experimental acute pancreatitis Gastroenterology 108 1995 1917 1922
12. KJ Pennline GE Roque M Monahan Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse Clin Immunol Immunopathol 71 1994 169 175
13. C Gerard C Bruyns A Marchant D Abramowicz P Vandenabeele A Delvaux W Fiers M Goldman T Velu Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia J Exp Med 177 1993 547 550
14. Z Xing Y Ohkawara M Jordana FL Graham J Gauldie Adenoviral vector-mediated interleukin-10 expression in vivo: intramuscular gene transfer inhibits cytokine responses in endotoxemia Gene Ther 4 1997 140 149
15. MS Mulligan RL Warner JL Foreback TP Shanley PA Ward Protective effects of IL-4, IL-10, IL-12, and IL-13 in IgG immune complex–induced lung injury: role of endogenous IL-12 J Immunol 159 1997 3483 3489
16. + T cells Immunity 1 1994 553 562
17. HH Herfarth SP Mohanty HC Rath S Tonkonogy RB Sartor Interleukin-10 suppresses chronic granulomatous inflammation induced by bacterial cell wall polymers in a rat model Gut 39 1996 836 845
18. SB Hanauer Inflammatory bowel disease N Engl J Med 334 1996 841 848
19. RP Schleimer An overview of gluccorticoid anti-inflammatory actions Eur J Clin Pharmacol 45 1993 3 7
20. RB Evans-Stormes JA Cidlowski Regulation of apoptosis by steroid hormones J Steroid Biochem Mol Biol 53 1995 1 8
21. JH Schwab Phlogistic properties of peptidoglycan-polysaccharide polymers from cell walls of pathogenic and normal-flora bacteria which colonize humans Infect Immun 61 1993 4535 4539
22. RB Sartor RA DeLa Cadena KD Green A Stadnicki SW Davis JH Schwab AA Adam P Raymond RW Colman Selective kallikrein-kinin system activation in inbred rats differentially susceptible to granulomatous enterocolitis Gastroenterology 110 1996 1467 1481
23. RD McCall S Haskill EM Zimmermann PK Lund RC Thompson RB Sartor Tissue interleukin-1 and interleukin-1 receptor antagonist expression in enterocolitis in resistant and susceptible rats Gastroenterology 106 1994 960 972
24. RL Wilder JB Allen C Hansen Thymus-dependent and -independent regulation of Ia antigen expression in situ by cells in the synovium of rats with streptococcal cell wall–induced arthritis. Differences in site and intensity of expression in euthymic, athymic, and cyclosporin A–treated LEW and F344 rats J Clin Invest 79 1987 1160 1171
25. JB Allen DE Yocum RL Wilder SM Wahl Inhibition by cyclosporin A of streptococcal cell wall–induced hepatic granulomas in LEW/N rats Ann N Y Acad Sci 465 1986 351 361
26. RB Sartor DE Bender JB Allen EM Zimmermann LC Holt MS Pardo PK Lund SM Wahl Chronic experimental enterocolitis and extraintestinal inflammation are T-lymphocyte dependent (abstr) Gastroenterology 104 1993 A775
27. JB Allen DG Malone SM Wahl GB Calandra RL Wilder Role of the thymus in streptococcal cell wall–induced arthritis and hepatic granuloma formation. Comparative studies of pathology and cell wall distribution in athymic and euthymic rats J Clin Invest 76 1985 1042 1056
28. SA Stimpson JH Schwab Chronic remittent erosive arthritis induced by bacterial peptidoglycan polysaccharide structures JY Chang AJ Lewis Pharmacological methods in the control of inflammation Volume 5 1989 Liss New York 381 394
29. MB Grisham JN Benoit DN Granger Assessment of leukocyte involvement during ischemia and reperfusion of intestine Methods Enzymol 186 1990 729 742
30. A Boyum Isolation of mononuclear cells and granulocytes from human blood Scand J Clin Lab Invest 21 1968 77 88
31. HC Rath HH Herfarth JS Ikeda WB Grenther TE Hamm JD Balish RE Taurog RE Hammer KH Wilson RB Sartor Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human b2 microglobulin transgenic rats J Clin Invest 98 1996 945 953
32. S Van Deventer CO Elson RN Fedorak Multiple doses of intravenous interleukin-10 in steroid-refractory Crohn's disease Gastroenterology 113 1997 383 389
33. M Walmsley PD Katsikis E Abney S Parry RO Williams RN Maini M Feldmann Interleukin-10 inhibition of the progression of established collagen-induced arthritis Arthritis Rheum 39 1996 495 503
34. F Powrie S Menon RL Coffman Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo Eur J Immunol 23 1993 2223 2229
35. TR Cupps AS Fausi Glucocorticoid-mediated immunoregulation in man Immunol Rev 65 1982 133 155
36. DA Joyce JA Steer A Kloda DEX antagonizes IL-4 and IL-10-induced release of IL-1RA by monocytes but augments IL-4-, IL-10-, and TGF-β induced suppression of TNF-α release J Interferon Cytokine Res 16 1996 511 517
37. J Sauer M Castren U Hopfner F Holsboer GK Stalla Inhibition of LPS-induced monocyte interleukin-1 receptor antagonist synthesis by cortisol: involvement of the mineralocorticoid receptor J Clin Endocrinol Metab 81 1995 73 79
38. MA Cassatella L Meda S Gasperini F Calzetti S Bonora Interleukin 10 (IL-10) upregulates IL-1 receptor antagonist production from lipopolysaccharide-stimulated human polymorpho-nuclear leukocytes by delaying mRNA degradation J Exp Med 179 1994 1695 1699
39. WP Arend Interleukin-receptor antagonist Adv Immunol 54 1993 167 227
40. F Cominelli CC Nast A Duchini M Lee Recombinant interleukin-1 receptor antagonist blocks the proinflammatory activity of endogenous interleukin-1 in rabbit immune colitis Gastroenterology 103 1992 65 71
41. M Ferretti V Casini-Raggi TT Pizarro SP Eisenberg CC Nast F Cominelli Neutralisation of endogenous IL-1 receptor antagonist exacerbates and prolongs inflammation in rabbit immune colitis J Clin Invest 94 1994 449 453
42. Straub RH, Herfarth H, Rinkes B, Konecna L, Glück T, Landenberg P, Georgi J, Helmke K, Schölmerich J, Vaith P, Lang B. Favorable role of interleukin 10 in patients with polymyalgia rheumatica (submitted).
43. WE Paul RA Seder Lymphocyte responses and cytokines Cell 76 1994 241 251
44. + T cells in vitro J Immunol 156 1996 2406 2412
45. + subsets J Immunol 155 1995 3322 3328
46. DF Fiorentino MW Bond TR Mosmann Two types of mouse T helper cell. IV: Th2 clones secrete a factor that inhibits cytokine production by Th1 clones J Exp Med 170 1989 2081 2095
47. B Koppelman JJ Neefjes JE de Vries R de Waal Malefyt Interleukin-10 down-regulates MHC class II alphabeta peptide complexes at the plasma membrane of monocytes by affecting arrival and recycling Immunity 7 1997 861 871
48. L Ding EM Shevach IL-10 inhibits mitogen-induced T cell proliferation by selectively inhibiting macrophage costimulatory function J Immunol 148 1992 3133 3139
49. K Madsen R Fedorak M Tavernini J Hibbard SP Lewis Interleukin 10 prevents cytokine-induced disruption of T84 monolayer barrier integrity and limits chloride secretion Gastroenterology 113 1997 151 159
50. + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis Nature 389 1997 737 742
51. P Wang MI Siegel RW Egan MM Billah Interleukin (IL)-10 inhibits nuclear factor kB (NFkB) activation in human monocytes J Biol Chem 270 1995 9558 9563
52. RI Scheinman PC Cogswell AK Lofquist ASJ Baldwin Role of transcriptional activation of IkBa in mediation of immunosuppression by glucocorticoids Science 270 1995 283 286
53. N Auphan JA Didonato C Rosette A Helmberg M Karin Immunosuppression by glucocorticoids: inhibition of NF-kB activity through induction of IkB synthesis Science 270 1995 286 290
54. MF Romano A Lamberti A Petrella R Bisogni PF Tassone S Formisano S Venuta MC Turco IL-10 inhibits nuclear factor-kappa B/Rel nuclear activity in CD3-stimulated human peripheral T lymphocytes J Immunol 156 1996 2119 2123
55. AB Lentsch TP Shanley V Sarma PA Ward In vivo suppression of NF-kappa B and preservation of I kappa B alpha by interleukin-10 and interleukin-13 J Clin Invest 100 1997 2443 2448
56. MJ May S Gosh Signal transduction through NF-kB Immunol Today 19 1998 80 88
57. AJ Schottelius MW Mayo RB Sartor AS Baldwin Jr IL-10 modulates NF-kB activity in human monocytic cell lines by blocking DNA binding rather than inhibiting nuclear translocation (abstr) Gastroenterology 114 1998 A1080
58. C Jobin HH Herfarth RB Sartor DEX inhibits TNF-α gene expression through an IkB/NF-kB pathway in intestinal IEC-6 cells (abstr) Gastroenterology 110 1996 A333
59. + Th1-like responses J Clin Invest 98 1996 1010 1020
60. DF Fiorentino A Zlotnik TR Mosmann M Howard A O'Garra IL-10 inhibits cytokine production by activated macrophages J Immunol 147 1991 315 322
61. PO Flores-Villanueva XX Zheng TB Strom MJ Stadecker Recombinant IL-10 and IL-10/Fc treatment down-regulate egg antigen-specific delayed hypersensitivity reactions and egg granuloma formation in schistosomiasis J Immunol 156 1996 3315 3320
62. S Schreiber RN Fedorak OH Nielson G Wild NC Williams M Jacyna BA Lashner M Cohard A Kilian A Lebeaut SB Hanauer the Crohn's disease IL-10 cooperative study group A safety and efficacy study of recombinant human interleukin-10 (rHuIL-10) treatment in 329 patients with chronic active Crohn's disease (CACD) (abstr) Gastroenterology 114 1998 A1080