Two threonine residues in the M2 segment of the α1β1 GABA(A) receptor are critical for ion channel function.

Receptors and Channels

Volumn 5, Issue 2, 1997, Pages 113-124

  Tierney, M L ^a   Birnir, B ^a   Cromer, B ^a   Howitt, S M ^a   Gage, P W ^a   Cox, G B ^a,b  

^a Australian National University   (Australia)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

aminobutyric acid; Ion channel; Mutagenesis; Receptor; Threonine

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; CHLORIDE ION; ION CHANNEL; MUSCIMOL; MUTANT PROTEIN; THREONINE; TRITIUM;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BACULOVIRUS; CHLORIDE CURRENT; CONTROLLED STUDY; GENE EXPRESSION SYSTEM; INSECT; ION CURRENT; NONHUMAN; PRIORITY JOURNAL; RADIOASSAY; STRUCTURE ACTIVITY RELATION;

ALANINE; AMINO ACID SEQUENCE; CELL MEMBRANE; CHLORIDE CHANNELS; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, GABA-A; THREONINE; TRITIUM;

ANIMALIA; INSECTA; TRITIUM; UNIDENTIFIED BACULOVIRUS;

EID: 0031390723     PISSN: 10606823     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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