mph1, a member of the Mps1-like family of dual specificity protein kinases, is required for the spindle checkpoint in S. pombe

Journal of Cell Science

Volumn 111, Issue 12, 1998, Pages 1635-1647

  He, Xiangwei ^a   Jones, Michele H ^b   Winey, Mark ^b   Sazer, Shelley ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

mph1 kinase; Spindle checkpoint; Spindle pole body duplication

Indexed keywords

PROTEIN KINASE;

ARTICLE; FUNGAL GENETICS; GENE ISOLATION; GENE OVEREXPRESSION; GENETIC COMPLEMENTATION; METAPHASE; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; SCHIZOSACCHAROMYCES POMBE;

AMINO ACID SEQUENCE; CALCIUM-BINDING PROTEINS; CARRIER PROTEINS; CELL CYCLE PROTEINS; CONSERVED SEQUENCE; DNA, COMPLEMENTARY; FUNGAL PROTEINS; METAPHASE; MITOTIC SPINDLE APPARATUS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; UBIQUITINS;

SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES; SCHIZOSACCHAROMYCES POMBE; SCHIZOSACCHAROMYCETACEAE;

EID: 0031848888     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Biggins, S., Ivanovska, I. and Rose, M. (1996). Yeast ubiquitin-like genes are involved in duplication of the microtubule organizing center. J. Cell Biol. 133, 1331-1346.
2. Byers, B. (1981). Cytology of the yeast cell cycle. In The Molecular Biology of the Yeast Saccharomyces cerevisiae I. Life Cycle and Inheritance (ed. J. Strathern, E. Jones and J. Broach). pp. 59-96. Cold Spring Harbor. NY: Cold Spring harbor Press.
3. Carr, A. M., MacNeill, S. A., Hayles, J. and Nurse, P. (1989). Molecular cloning and sequence analysis of mutant alleles of the fission yeast cdc2 protein kinase gene: implications for cdc2 + protein structure and function. Mol. Gen. Genet. 218, 41-49.
4. Chen. R., Waters, J. C., Salmon, E. D. and Murray, A. W. (1996). Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores. Science 274, 242-246.
5. Cohen-Fix, O., Peters, J., Kirschner, M. and Koshland, D. (1996). Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. Genes Dev 10. 3081-3093.
6. Dins, R., West, R. R., Morphew, D. M., Oakley, B. R. and McIntosh, J. R. (1997). The spindle pole body ot Schizosaccharomyces pombe enters and leaves the nuclear envelope as the cell cycle proceeds. Mol. Biol. Cell 8, 1461-1479.
7. Douville, E. M., Afar, D. E., Howell, B. W., Letwin, K., Tannock, L., Ben-David, Y., Pawson, T. and Bell, J. C. (1992) Multiple cDNAs encoding the esk kinase predict transmembrane and intracellular enzyme isoforms. Mol. Cell. Biol. 12, 2681-2680.
8. Fankhauser, C., Marks, J., Reymond, A. and Simanis, V. (1993). The S. pombe cdc16 gene is required both for maintenance of p34cdc2 kinase activity and regulation of septum formation a link between mitosis and cytokinesis. EMBO J. 12, 2697-2704.
9. Forsburg, S. L. (1993). Comparison of Schizosaccharomyces, pombe expression systems. Nucl. Acids. Res. 21, 2955-2956.
10. Funabiki, H., Yamano, H., Kumada, K., Nagao, K., Hunt, T. and Yanagida, M. (1996). Cut2 proleolysis required for sister-chromatid separation in fission yeast. Nature 381, 438-441.
11. Geiser, J. R., Schott, E. J., Kingsbury, T. J., Cole, N. B., Totis, L. J., Bhattacharyya, G., He, L. and Hoyt, M. A. (1997). Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways. Mol. Biol. Cell 8, 1035-1050
12. Gorbsky, G. J. and Ricketts, W. A. (1993). Differential expression of a phosphoepitope at the kinetochores of moving chromosomes. J. Cell Biol. 122, 1311-1321.
13. Hagan, I. and Hyams, J. (1988). The use of cell division cycle mutants to investigate the control of microtubule distribution in the fission yeast Schizosaccharomyces pombe. J. Cell .Sri. 89, 343-357.
14. Hagan, I. and Yanagida, M. (1995). The product of the spindle formation gene sadl1 associates with the fission yeast spindle pole body and is essential for viability. J. Cell Biol. 129, 1033-1047.
15. Hardwick, K. G. and Murray, A. W. (1995) Madlp. a phosphoprotein component of the spindle assembly checkpoint in budding yeast. J Cell Biol 131, 709-720.
16. Hardwick, K., Weiss, E., Luca, F., Winey, M. and Murray, A. (1996) Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. Science 273, 953-956.
17. He, X., Patterson, T. and Sazer, S. (1997) The Schizosaccharomyces pombe spindle Checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex. Proc. Nat. Acad. Sci. USA 94, 7965-7970.
18. He. X., Hayashi, N., Walcott, N. G., Azuma. Y., Patterson, T. E., Bischoff, F. R., Nishimoto, T. and Sazer, S. (1998). The identification of cDNAs that affect the mitosis-to-interphase transition in Schizosaccharomyces pombe. including sbpl which encodes a spilp-GTP binding protein, Genetics 148, 645-656.
19. Hiraoka, V., Toda, T. and Yanagida, M. (1984). The NDA3 gene of fission yeast encodes β-tubulin: a cold-sensitive nda3 mutation reversibly blocks spindle formation and chromosome movement in mitosis Cell 39, 349-358
20. Hoheisel, J. D., Maier, E., Mott, R., McCarthy, L., Grigories, A. V., Schalkwyk, L. C., Nizctic, D., Francis, F. and Lehrach, H. (1993). High resolution cosmid and P1 Maps spanning the 14 Mb genome of the fission yeast S. pombe. Cell 73, 109-120.
21. Holloway, S. L., Glotzer, M., King, R. W. and Murray, A. W. (1993). Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor. Cell 73, 1393-1402.
22. Hoyt. M. A., Totis, L. and Roberts, B. T. (1991). S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function. Cell 66. 507-517.
23. Hutter, K. J. and Eipel, H. E. (1979). Microbial determination by flow cytometry. J. Gen. Microbiol. 113, 369-375.
24. Irniger, S., Piatti, S., Michaelis, C. and Nasmyth, K. (1995) Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast. Cell 81, 269-278.
25. Kanbe, T., Hiraoka, V., Tanaka, K. and Yanagida, M. (1990). The transition of cells of the fission yeast beta-tubulin mutant nda3-311 as seen by freeze-substitution electron microscopy. J. Cell . Sci. 96, 275-182.
26. King, R. W., Peters, J. M., Tugendreich, S., Rolfe, M., Hieter, P. and Kirschner, M. W. (1995). A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell 81, 279-288.
27. Lauze, E., Stoelcker, B., Luca, F. C., Weiss, E., Schutz, A. R. and Winey, M. (1995) Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase. EMBO J. 14, 1655-1663
28. Lehrach, H. R., Drmanac, R., Hoheisel, J., Larin, Z., Lennon, G., Monaco, A. P., Nizetic, D., Zehetner, G. and Poustka, A. (1990). Hybridization fingerprinting in genome mapping and sequencing. In Genetic unit Physical Mapping (ed. K. E. Davies and S. M. Tilghmanl. pp. 39-81. Cold Spring Harbor. NY: Cold Spring Harbor Laboratory Press.
29. Li, R. and Murray, A. W. (1991). Feedback control of mitosis in budding yeast [published erratum appears in Cell (1994) 79. following p. 388]. Cell 66, 519-531.
30. Li, X. and Nicklas, R. B. (1995). Mitotic forces control a cell-cycle checkpoint. Nature 373, 630-632.
31. Li, X. and Nicklas, R. B. (1997). Tension-sensitise kinetochore phosphorylation and the chromosome distribution checkpoint in praying mantid spematocytes. J. Cell Sci. 110, 537-545
32. Li, Y. and Benezra, R. (1996). Identification of a human mitotic checkpoint gene: HsMAD2. Science 274, 246-248.
33. Masuda, H. and Shibata, T. (1996). Role of gamma-tubulin in mitosis-specific microtubule nucleation from the Schizosaccharomyces pombe spindle pole body. J Cell Sci. 109, 165-177.
34. Maundrell, K. (1993). Thiamine-repressible expression vectors pREP and pRIP for fission yeast, Gene 123, 127-130.
35. Mills, G. B., Schmandt, R., McGill, M., Amendola, A., Hill, M., Jacobs, K., May, C., Rodricks, A. M., Campbell, S. and Hogg, D. (1992). Expression of TTK. a novel human protein kinase is associated with cell proliferation. J. Biol. Chem. 267, 16000-16006.
36. Minshull, J., Sun, H., Tonks, N. K. and Murray, A. W. (1994). A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts Cell 79, 475-486.
37. Moreno, S., Hayles, J. and Nurse, P. (1989). Regulation of p34cdc2 protein kinase during mitosis. Cell 58, 361-372
38. Moreno, S., Klar, A. and Nurse, P. (1991). Molecular genetic analysis of fission yeast Schizasaccharomyces pombe. Meth Eazymol. 194. 795-823.
39. Moser, M. J., Flory, M. R. and Davis, T. N. (1997). Calmodulin localized to the spindle pole body of Schizosaccharomyces pombe and performs an essential function in chromosome segregation. J. Cell Sci. 110, 1805-1812
40. Murone, M. and Simanis, V. (1996). The fission yeast dmal gene is a component of the spindle assembly chechpoint. required to prevent septum formation and premature exit from mitosis if spindle function is compromised. EMBO J. 15, 6605-6616.
41. Nicklas, R. B., Ward, S. C. and Gorbsky, G. J. (1995) Kinetochore chemistry is sensitive to tension and may link mitotie forces to a cell cycle checkpoint. J. Cell Biol. 130, 929-939.
42. Page, B. D. and Snyder, M. (1993). Chromosome segregation in yeast Annu. Rev. Microbiol. 47, 231-261.
43. Piatti, S., Lengauer, C. and Nasmyth, K. (1995). Cde6 is an unstable protein whose de novo synthesis in G1 is important for the onset ot S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae. EMBO J. 14, 3788-3799.
44. Rattner, J. B. and Phillips, S. G. (1973). Independence of centriole formation and DNA synthesis. J. Cell Biol. 57, 359-372.
45. Roberts, B., Farr, K. and Hoyt, M. (1994). The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase. Mol. Cell Biol 14, 8282-8291.
46. Rose, M. and Fink, G. (1987). KARI, a gene required for function of both intranuclear and extranuclear microtubules in yeast. Cell 48, 1047-1060.
47. Rudner, A. D. and Murray, A. W. (1996). The spindle assembly checkpoint. Curr. Opin. Cell Biol. 8, 773-780.
48. Sikorski, R. S. and Heiter, P. (1989). A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharmyces cerevisiae. Genetic. 122, 19-27.
49. Snyder, M. (1994). The spindle pole body of yeast Chromosoma 103, 369-380.
50. Surana, U., Amon, A., Dowzer, C., McGrew, J., Byers, B. and Nasmyth, K. (1993) Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast. EMBO J. 12, 1969-1978.
51. Taylor, S. and McKeon, F. (1997). Kinetochore localization of murine Bubl is required for normal mitotic timing and checkpoint response to spindle damage. Cell 89, 727-735.
52. Wang, Y. and Burke, D. (1997). Cde55p. the B-type regulatory subunit of protein phosphatase 2A. has multiple functions in mitosis and is required for the kinetochore/spindle checkpoint in Saccharomyces cerevistae. Mol. Cell. Biol. 17, 620-626.
53. Weiss, E. and Winey, M. (1996). The Saccharomyces cerevisiae spindle pole-body duplication gene MPSI is part of a mitotic checkpoint. J. Cell Biol. 132, 111-23.
54. Winey. M., Goetsch, L., Baum, P. and Byers, B. (1991) MPS1 and MPS2: novel yeast genes defining distinct steps of spindle pole body duplication. J. Cell Biol. 114, 745-754.
55. Woods, A., Sherwin, T., Sasse, R., MacRae, T. H., Baines, A. J. and Gull, K. (1989). Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies. J. Cell Sci. 93. 491-500.
56. Yamano, H., Gannon, J. and Hunt, T. (1996). The rule of proteolysis in cell cycle progression in Schizosaccharomyces pombe EMBO J. 15, 5268-79