Protection of T cells from activation-induced cell death by Fas+ B cells

European Journal of Immunology

Volumn 30, Issue 3, 2000, Pages 931-937

  Wang, Julia K M ^a   Ju, Shyr Te ^a   Marshak Rothstein, Ann ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Activation induced cell death; B lymphocyte; Fas; Fas ligand; T B interaction

Indexed keywords

CD4 ANTIGEN; CELL RECEPTOR; FAS LIGAND; IMMUNOGLOBULIN M; STAPHYLOCOCCUS ENTEROTOXIN B; SUPERANTIGEN;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL DEATH; CELL INTERACTION; CELL PROLIFERATION; CELL PROTECTION; CELL STIMULATION; CONTROLLED STUDY; CYTOLYSIS; IMMUNOSTIMULATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

EID: 0033993509     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200003)30:3<931::AID-IMMU931>3.0.CO;2-H     Document Type: Article

References (36)

1. Lenardo, M. J., Interleukin-2 programs mouse αβ T lymphocytes for apoptosis. Nature 1991. 353: 858-861.
2. Radvanyi, L. G., Mills, G. B. and Miller, R. G., Religation of the T cell receptor after primary activation of mature T cells inhibits proliferation and induces apoptotic cell death. J. Immunol. 1993. 150: 5704-5715.
3. Russell, J. H., Rush, B., Weaver, C. and Wang, R., Mature T cells of autoimmune Ipr/Ipr mice have a defect in antigen-stimulated suicide. Proc. Natl. Acad. Sci. USA 1993. 90: 4409-4413.
4. Russell, J. H. and Wang, R., Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cells. Eur. J. Immunol. 1993. 23: 2379-2382.
5. Ettinger, R., Panka, D. J., Wang, J. K. M., Stanger, B. Z., Ju, S.-T. and Marshak-Rothstein, A., Fas-ligand mediated cytotoxicity is directly responsible for apoptosis of normal CD4+ T cells responding to a bacterial superantigen. J. Immunol. 1995. 154: 4302-4308.
6. Dhein, J., Walczak, H., Baumier, C., Debatin, K.-M. and Krammer, P. H., Autocrine T-cell suicide mediated by APO-1/Fas/ CD95. Nature 1995. 373: 438-441.
7. Brunner, T., Mogil, R. J., LaFace, D., Yoo, N. J., Mahboubi, A., Echeverri, F., Martin, S. J., Force, W. R., Lynch, D. H., Ware, C. F. and Green, D. R., Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 1995. 373: 441-444.
8. Ju, S.-T., Panka, D. J., Cui, H., Ettinger, R., El-Khatib, M., Sherr, D. H., Stanger, B. Z. and Marshak-Rothstein, A., Fas (CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature 1995. 373: 444-448.
9. Wang, J. K. M., Zhu, B., Ju, S.-T., Tschopp, J. and Marshak-Rothstein, A., CD4+ T cells reactivated with superantigen are both more sensitive to FasL-mediated killing and express a higher level of FasL. Cell, Immunol. 1997. 179: 153-164.
10. Brunner, T., Yoo, N. J., LaFace, D., Ware, C. F. and Green, D. R., Activation-induced cell death in murine T cell hybridomas. Differential regulation of Fas (CD95) versus Fas ligand expression by cyclosporin A and FK506. Int. Immunol. 1996. 8: 1017-1026.
11. Wong, B., Arron, J. and Choi, Y., T cell receptor signals enhance susceptibility to Fas-mediated apoptosis. J. Exp. Med. 1997. 186: 1939-1944.
12. Nagata, S. and Golstein, P., The Fas death factor. Science 1995. 267: 1449-1456.
13. Chinnaiyan, A. M. and Dixit, V. M., Portrait of an executioner: the molecular mechanism of FAS/APO-1 -induced apoptosis. Semin. Immunol. 1997. 9: 69-76.
14. Boehme, S. A. and Lenardo, M. J., Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle. Eur. J. Immunol. 1993. 23: 1552-1560.
15. Radvanyi, L. G., Shi, Y., Mills, G. B. and Miller, R. G., Cell cycle progression out of G1 sensitizes primary-cultures nontransformed T cells to TCR-mediated apoptosis. Cell. Immunol. 1996. 170: 260-273.
16. Zhang, L., Trageser, C. L, Willerford, D. M. and Lenardo, M. J., T cell growth cytokines cause the super-induction of molecules mediating antigen-induced T lymphocyte death. J. Immunol. 1998. 160: 763-769.
17. Algeciras-Schimnich, A., Griffith, T. S., Lynch, D. H. and Paya, C. V., Cell cycle-dependent regulation of FLIP levels and susceptibility to Fas-mediated apoptosis. J. Immunol. 1999. 162: 5205-5211.
18. Refaeli, Y., Van Parijs, L., London, C. A., Tschopp, J. and Abbas, A. K., Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis. Immunity 1998. 8: 615-623.
19. Foote, L. C., Howard, R. G., Marshak-Rothstein, A. and Rothstein, T. L., IL-4 induces Fas resistance in B cells. J. Immunol. 1996. 157: 2749-2753.
20. Zhang, X. L., Giangreco, L., Broome, H. E., Dargan, C. M. and Swain, S. L., Control of CD4 effector fate: transforming growth factor beta 1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion. J. Exp. Med. 1995. 182: 699-709.
21. Ayroldi, E., Zollo, O., Cannarile, L., D'Adamio, F., Grohmann, U., Delfino, D. V. and Riccardi, C., lnterleukin-6 (IL-6) prevents activation-induced cell death: IL-2-independent inhibition of Fas/ FasL expression and cell death. Blood 1998. 92: 4212-4219.
22. Stalder, T., Hahn, S. and Erb, P., Fas antigen is the major target molecule for CD4+ T cell-mediated cytotoxicity. J. Immunol. 1994. 152: 1127-1133.
23. Rothstein, T. L., Wang, J. K. M., Panka, D. J., Foote, L. C., Wang, Z., Stanger, B., Cui, H., Ju, S.-T. and Marshak-Rothstein, A., Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells. Nature 1995. 374: 163-165.
24. Schattner, E. J., Elkon, K. B., You, D. H., Tumang, J., Krammer, P. H., Crow, M. K. and Friedman, S. M., CD40L ligation induces Apo-1/Fas expression on human B lymphocytes and facilitates apoptosis through the Apo-1/fas pathway. J. Exp. Med. 1995. 182: 1557-1565.
25. Hahne, M., Renno, T., Schroeter, M., Irmler, M., French, L., Bornard, T., MacDonald, H. R. and Tschopp, J., Activated B cells express functional Fas ligand. Eur. J. Immunol. 1996. 26: 721-724.
26. Foote, L. C., Schneider, T. J., Fisher, G. M., Wang, J. K. M., Rasmussen, B., Campbell, K. A., Lynch, D. H., Ju, S.-T., Marshak-Rothstein, A. and Rothstein, T. L., lntracellular signalling for inducible antigen receptor mediated Fas-resistance in B cells. J. Immunol. 1996. 157: 1878-1885.
27. Schneider, T. J., Fischer, G. M., Donohue, T. J., Colarusso, T. P. and Rothstein, T. L., A novel gene coding for a Fas apoptosis inhibitory molecule (FAIM) isolated from inducibly Fas-resistant B cells. J. Exp. Med. 1999. 189: 949-956.
28. Rathmell, J. C., Cooke, M. P., Ho, W. Y., Grein, J., Townsend, S. E., Davis, M. M. and Goodnow, C. C., CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells. Nature 1995. 376: 181-184.
29. Foote, L. C., Marshak-Rothstein, A. and Rothstein, T. L., Tolerant B cells acquire resistance to Fas-mediated apoptosis after treatment with interteukin-4 but not after treatment with specific antigen unless a surface immunoglobulin threshold is exceeded. J. Exp. Med. 1998. 187: 847-853.
30. Ozdemirli, M., EI-Khatib, M., Foote, L. C., Wang, J. K. M., Marshak-Rothstein, A., Rothstein, T. L. and Ju, S.-T, Fas (CD95)/Fas ligand interactions regulate antigen-specific, major histocompatibility complex-restricted T/B cell proliferate responses. Eur. J. Immunol. 1996. 26: 415-419.
31. Griffith, T. S., Yu, X., Herndon, J. M., Green, D. R. and Ferguson, T. A., CD95-induced apoptosis of lymphocytes in an immune privileged site induces immunological tolerance. Immunity 1996. 5: 7-16.
32. Bonfoco, E., Stuart, P. M., Brunner, T., Lin, T., Griffith, T. S., Yakun, G., Nakajima, H., Henkart, P. A., Ferguson, T. A. and Green, D. R., Inducible nonlymphoid expression of Fas ligand is responsible for superantigen-induced peripheral deletion of T cells. Immunity 1998. 9: 711-720.
33. DiSomma, M. M., Somma, F., Montani, M. S., Mangiacasale, R., Cundari, E. and Piccolella, E., TCR engagement regulates differential responsiveness of human memory T cells to Fas (CD95)-mediated apoptosis. J. Immunol. 1999. 162: 3851-3858.
34. Suzuki, I. and Fink, P. J., Maximal proliferation of cytotoxic T lymphocytes requires reverse signaling through Fas ligand. J. Exp. Med. 1998. 187: 123-128.
35. Desbarats, J., Duke, R. C. and Newell, M. K., Newly discovered role for Fas ligand in the cell-cycle arrest of CD4+ T cells. Nat. Med. 1998. 4: 1377-1382.
36. Lane, P., Brocker, T., Hubele, S., Padovan, E., Lanzavecchia, A. and McConnell, F., Soluble CD40 ligand can replace the normal T-cell derived CD40 ligand signal to B cells in T cell-dependent activation. J. Exp. Med. 1993. 177: 1209-1213.