Regulation of integrin function: Evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin α5β1

Biochemical Journal

Volumn 331, Issue 3, 1998, Pages 821-828

  Mould, A Paul ^a   Garratt, Alistair N ^a,c   Puzon McLaughlin, Wilma ^b   Takada, Yoshikazu ^b   Humphries, Martin J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; DIVALENT CATION; INTEGRIN; MAGNESIUM ION; MANGANESE; MONOCLONAL ANTIBODY; PROTEIN SUBUNIT; VON WILLEBRAND FACTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; ENZYME LINKED IMMUNOSORBENT ASSAY; LIGAND BINDING; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN TERTIARY STRUCTURE; REGULATORY MECHANISM;

EID: 0032079781     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3310821     Document Type: Article

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