Defining the topology of integrin α5β1-fibronectin interactions using inhibitory anti-α5 and anti-β1 monoclonal antibodies: Evidence that the synergy sequence of fibronectin is recognized by the amino-terminal repeats of the α5 subunit

Journal of Biological Chemistry

Volumn 272, Issue 28, 1997, Pages 17283-17292

  Mould, A Paul ^a   Askari, Janet A ^a   Aota, Shin Ichi ^b   Yamada, Kenneth M ^b   Irie, Atsushi ^c   Takada, Yoshikazu ^c   Mardon, Helen J ^d   Humphries, Martin J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; FIBRONECTIN; INTEGRIN; LIGAND; MONOCLONAL ANTIBODY; PROTEIN SUBUNIT;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL DIFFERENTIATION; CELL MIGRATION; CELL SURVIVAL; EPITOPE MAPPING; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD29; BINDING SITES; EPITOPE MAPPING; HUMANS; INTEGRIN ALPHA5; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PROTEIN BINDING; RATS; RECEPTORS, FIBRONECTIN; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPSIN;

EID: 0030798854     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.28.17283     Document Type: Article

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