α4 Integrin binding interfaces on VCAM-1 and MADCAM-1: Integrin binding footprints identify accessory binding sites that play a role in integrin specificity

Journal of Biological Chemistry

Volumn 272, Issue 31, 1997, Pages 19429-19440

  Newham, Peter ^a   Craig, Susan E ^a   Seddon, Garry N ^e   Schofield, Neil R ^a   Rees, Amanda ^b   Edwards, R Mark ^c   Jones, E Yvonne ^d   Humphries, Martin J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

^c British Biotechnology   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE PROTEIN; FC RECEPTOR; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; MONOCLONAL ANTIBODY; VASCULAR CELL ADHESION MOLECULE 1; ALPHA4 INTEGRIN; ARGINYL-GLYCYL-ASPARTIC ACID; ARGINYLGLYCYLASPARTIC ACID; IMMUNOGLOBULIN; LEUKOCYTE ANTIGEN; MADCAM1 PROTEIN, HUMAN; MUCOPROTEIN; OLIGOPEPTIDE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CELL ADHESION; CELL INTERACTION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE MUTATION; HUMAN; HUMAN CELL; LEUKOCYTE ADHERENCE; MELANOMA CELL; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CELL CULTURE; CELL STRAIN COS1; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD; BINDING SITES; COS CELLS; HUMANS; IMMUNOGLOBULINS; INTEGRIN ALPHA4; MOLECULAR SEQUENCE DATA; MUCOPROTEINS; MUTAGENESIS, SITE-DIRECTED; OLIGOPEPTIDES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0030612147     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.31.19429     Document Type: Article

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