Recombinant Semliki Forest virus particles expressing louping ill virus antigens induce a better protective response than plasmid-based DNA vaccines or an inactivated whole particle vaccine

Journal of General Virology

Volumn 81, Issue 3, 2000, Pages 749-758

  Fleeton, Marina N ^a   Liljeström, Peter ^a,b   Sheahan, Brian J ^c   Atkins, Gregory J ^d  

^a KAROLINSKA INSTITUTE   (Sweden)

^b SWEDISH INSTITUTE FOR INFECTIOUS DISEASE CONTROL   (Sweden)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

^d TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; INACTIVATED VIRUS VACCINE; PLASMID DNA; VIRUS ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; ENCEPHALITIS; HUMORAL IMMUNITY; MALE; MOUSE; NERVE CELL DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST; SEMLIKI FOREST ALPHAVIRUS; SHEEP DISEASE; VIRUS PARTICLE; VIRUS VIRULENCE;

ALPHAVIRUS; ANIMALIA; LOUPING ILL VIRUS; OVIS ARIES; RABBIT FIBROMA VIRUS; RNA VIRUSES; SEMLIKI FOREST VIRUS;

EID: 0033981840     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-81-3-749     Document Type: Article

References (39)

1. 5 and CD36, and cross-present antigens to cytotoxic T lymphocytes. Journal of Experimental Medicine 188, 1359-1368.
2. Albert, M. L., Sauter, B. & Bhardwaj, N. (1998 b). Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature 392, 86-89.
3. Atkins, G. J. , Sheahan, B. J. & Liljeström, P. (1999). The molecular pathogenesis of Semliki Forest virus: a model virus made useful? Journal of General Virology 80, 2287-2297.
4. Berglund, P., Sjöberg, M., Atkins, G. J., Sheahan, B. J., Garoff, H. & Liljeström, P. (1993). Semliki Forest virus expression system: production of conditionally infectious recombinant particles. Bio/Technology 11, 916-920.
5. Berglund, P., Quesada-Rolander, M., Putkonen, P., Biberfeld, G., Thorstensson, R. & Liljeström, P. (1997). Outcome of immunization of cynomolgus monkeys with recombinant Semliki Forest virus encoding human immunodeficiency virus type 1 envelope protein and challenged with a high dose of SHIV-4 virus. AIDS Research and Human Retroviruses 13, 1487-1495.
6. Berglund, P., Fleeton, M., Smerdou, C., Tubulekas, I., Sheahan, B. J., Atkins, G. J. & Liljeström, P. (1998 a). Vaccination with recombinant suicidal DNA/RNA. In New Developments and New Applications in Animal Cell Technology. Edited by O. Merten, P. Perrin & B. Griffiths. Dordrecht: Kluwer Academic Publishers.
7. Berglund, P., Smerdou, C., Fleeton, M. N., Tubulekas, I. & Liljeström, P. (1998 b). Enhancing immune responses using suicidal DNA vaccines. Nature Biotechnology 16, 562-565.
8. Berglund, P., Fleeton, M. N., Smerdou, C. & Liljeström, P. (1999). Immunization with recombinant Semliki Forest virus induces protection against influenza challenge in mice. Vaccine 17, 497-507.
9. Colombage, G., Hall, R., Pavy, M. & Lobigs, M. (1998). DNA-based and alphavirus-vectored immunization with prM and E proteins elicits long-lived and protective immunity against the flavivirus, Murray Valley encephalitis virus. Virology 250, 151-163.
10. Davidson, M. M., Williams, H. & Macleod, A. J. (1991). Louping ill in man: a forgotten disease. Journal of Infection 23, 241-249.
11. Driver, D. A., Townsend, K., Brumm, D., Polo, J. M., Belli, B. A., Catton, D. J., Hsu, D., Mittelstaedt, D., McCormack, J. E., Karavodin, L., Dubensky, T. W., Chang, S. M. W. & Banks, T. A. (1998). DNA immunization against Herpes Simplex virus: enhanced efficacy using a Sindbis virus-based vector. Journal of Virology 72, 950-958.
12. Fleeton, M. N., Sheahan, B. J., Gould, E. A., Atkins, G. J. & Liljeström, P. (1999). Recombinant Semliki Forest virus particles encoding the prME or NS1 proteins of louping ill virus protect mice from lethal challenge. Journal of General Virology 80, 1189-1198.
13. Gao, G. F., Hussain, M. H., Reid, H. W. & Gould, E. A. (1994). Identification of naturally occurring monoclonal antibody escape variants of louping ill virus. Journal of General Virology 75, 609-614.
14. Glasgow, G. M., McGee, M. M., Mooney, D. A., Sheahan, B. J. & Atkins, G. J. (1997). Death mechanisms in cultured cells infected by Semliki Forest virus. Journal of General Virology 78, 1559-1563.
15. Glasgow, G. M., McGee, M. M., Tarbatt, C. J., Mooney, D. A., Sheahan, B. J. & Atkins, G. J. (1998). The Semliki Forest virus vector induces p53-independent apoptosis. Journal of General Virology 79, 2405-2410.
16. Heinz, F. X., Allison, S. L., Stiasny, K., Schalich, J., Holzman, H., Mandl, C. W. & Künz, C. (1995). Recombinant and virion-derived soluble and particulate immunogens for vaccination against tick-borne encephalitis. Vaccine 13, 1636-1642.
17. Jacobs, S. C., Stephenson, J. R. & Wilkinson, G. W. G. (1992). High level expression of the tick-borne encephalitis virus NS1 protein by using an adenovirus-based vector: protection elicited in a murine model. Journal of Virology 66, 2086-2095.
18. Kohno, A., Emi, N., Kasai, M., Tanimoto, M & Saito, H. (1998). Semliki Forest virus-based DNA expression vector - transient protein production followed by cell death. Gene Therapy 5, 415-418.
19. Konishi, E., Pincus, S., Paoletti, E., Shope, R. E., Burrage, T. & Mason, P. W. (1992). Mice immunized with a subviral particle containing the Japanese encephalitis virus prM/M and E proteins are protected from lethal JEV infection. Virology 188, 714-720.
20. Konishi, E., Yamaoka, M., Khin-Sane-Win, Kurane, I., Takada, K. & Mason, P. W. (1999). The anamnestic neutralising antibody response is critical for protection of mice from challenge following vaccination with a plasmid encoding the Japanese encephalitis virus premembrane and envelope genes. Journal of Virology 73, 5527-5534.
21. Koprowski, H. & Weiner, D. B. (1998). DNA vaccination/genetic vaccination. Current Topics in Microbiology and Immunology 226, 5-13.
22. Liljeström, P. & Garoff, H. (1991). A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Bio/ Technology 9, 1356-1361.
23. Lin, Y. L., Chen, L. K., Liao, C. L., Yen, C. T., Ma, S. H., Chen, J. L., Huang, Y. L., Chen, S. S. & Chiang, H. Y. (1998). DNA immunization with Japanese encephalitis virus nonstructural protein NS1 elicits protective immunity in mice. Journal of Virology 72, 191-200.
24. McGuire, K., Holmes, E. C., Gao, G. F., Reid, H. W. & Gould, E. A. (1998). Tracing the origins of louping ill virus by molecular phylogenetic analysis. Journal of General Virology 79, 981-988.
25. Monath, T. P. & Heinz, F. X. (1996). Flaviviruses. In fields Virology, 3rd edn, pp. 961-1034. Edited by B. N. Fields, D. M. Knipe & P. M. Howley. Philadelphia: Lippincott-Raven.
26. Mossman, S., Bex, F., Berglund, P., Arthos, J., O'Neill, S. P., Riley, D., Maul, D. H., Bruck, C., Momin, P., Burny, A., Fultz, P. N., Mullins, J. I., Liljeström, P. & Hoover, E. A. (1996). Protection against lethal SIVsmmPBj14 disease by a recombinant Semliki Forest virus gp160 vaccine and by gp120 subunit vaccine. Journal of Virology 70, 1953-1960.
27. Pugachev, K. V., Mason, P. W., Shope, R. E. & Frey, T. K. (1995). Double-subgenomic Sindbis virus recombinants expressing immunogenic proteins of Japanese encephalitis virus induce significant protection in mice against lethal JEV infection. Virology 212, 587-594.
28. Salminen, A., Wahlberg, J. M., Lobigs, M., Liljeström, P. & Garoff, H. (1992). Membrane fusion process of Semliki Forest virus. II. Cleavage-dependent reorganisation of the spike protein complex controls virus entry. Journal of Cell Biology 116, 349-357.
29. Schlesinger, J. J., Brandriss, M. W., Cropp, C. P. & Monath, T. P. (1986). Protection against yellow fever in monkeys by immunization with yellow fever nonstructural protein NS1. Journal of Virology 60, 1153-1155.
30. Schmaljohn, C., Vanderzanden, L., Bray, M., Custer, D., Meyer, B., Li, D., Rossi, C., Fuller, D., Fuller, J., Haynes, J. & Huggins, J. (1997). Naked DNA vaccines expressing the prM and E genes of Russian spring summer encephalitis virus and Central European encephalitis virus protect mice from homologous and heterologous challenge. Journal of Virology 71, 9563-9569.
31. Sheahan, B. J., Ibrahim, M. A. & Atkins, G. J. (1996). Demyelination of olfactory pathways in mice following intranasal infection with the avirulent A7 strain of Semliki Forest virus. European Journal of Veterinary Pathology 2, 117-125.
32. Shiu, S. Y. W., Reid, H. W. & Gould, E. A. (1992). Louping ill virus envelope protein expressed by recombinant baculovirus and vaccinia virus fails to stimulate protective immunity. Virus Research 26, 213-229.
33. Smerdou, C. & Liljeström, P. (1999 a). Non-viral amplification systems for gene transfer: vectors based on alphaviruses. Current Opinion in Molecular Therapy (in press).
34. Smerdou, C. & Liljeström, P. (1999 b). Two-helper RNA system for production of recombinant Semliki Forest virus particles. Journal of Virology 73, 1092-1098.
35. Timofeev, A. V., Ozherelkov, S. V., Pronin, A. V., Deeva, A. V., Karganova, G. G., Elbert, L. B. & Stephenson, J. R. (1998). Immunological basis for protection in a murine model of tick-borne encephalitis by a recombinant adenovirus carrying the gene encoding the NS1 non-structural protein. Journal of General Virology 79, 689-695.
36. Tubulekas, I., Berglund, P., Fleeton, M. & Liljeström, P. (1997). Alphavirus expression vectors and their use as recombinant vaccines - a minireview. Gene 190, 191-195.
37. Vene, S., Haglund, M., Vapalahti, O. & Lundkvist, A. (1998). A rapid fluorescent focus inhibition test for detection of neutralizing antibodies to tick-borne encephalitis virus. Journal of Virological Methods 73, 71-75.
38. Zhou, X. P., Berglund, G., Rhodes, G., Parker, S. E., Jondal, M. & Liljeström, P. (1994). Self-replicating Semliki Forest virus RNA as recombinant vaccine. Vaccine 12, 1510-1514.
39. Zhou, X. P., Berglund, G., Zhao, H., Liljeström, P. & Jondal, M. (1995). Generation of cytotoxic and humoral immune responses by non-replicative recombinant Semliki Forest virus. Proceedings of the National Academy of Sciences, USA 92, 3009-3013.