Protection against lethal simian immunodeficiency virus SIVsmmPBj14 disease by a recombinant Semliki forest virus gp160 vaccine and by a gp120 subunit vaccine

Journal of Virology

Volumn 70, Issue 3, 1996, Pages 1953-1960

  Mossman, Sally P ^a,h   Bex, Francoise ^b   Berglund, Peter ^c   Arthos, James ^d,i   O'Neil, Shawn P ^a   Riley, David ^d,h   Maul, Donald H ^a   Bruck, Claudine ^e   Momin, Patricia ^e   Burny, Arsene ^f   Fultz, Patricia N ^g   Mullins, James I ^d,h   Liljeström, Peter ^c   Hoover, Edward A ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e GLAXOSMITHKLINE BIOLOGICALS   (Belgium)

^f UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^g University of Alabama at Birmingham   (United States)

^h UNIVERSITY OF WASHINGTON   (United States)

ⁱ NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS VACCINE;

ANIMAL CELL; ANTIBODY TITER; ARTICLE; CELL PROTECTION; CELL SURVIVAL; IMMUNIZATION; LETHALITY; MACACA; MONKEY; NONHUMAN; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS INFECTION; VIRUS RECOMBINATION;

EID: 0344192533     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.3.1953-1960.1996     Document Type: Article

References (42)

1. Abimiku, A. G., G. Franchini, J. Tartaglia, K. Aldrich, M. Myagkikh, P. D. Markham, P. Chong, M. Klein, M.-P. Kieny, R. C. Gallo, and M. Robert-Guroff. 1995-HIV-1 recombinant poxvirus vaccine induces cross-protection against HIV-2 challenge in rhesus macaques. Nat. Med. 1:321-329.
2. Ahmad, S., B. Lohman, M. Marthas, L. Giavedoni, Z. El-Amad, N. L. Haigwood, C. J. Scandella, M. B. Gardner, P. A. Luciw, and T. Yilma. 1994. Reduced virus load in rhesus macaques immunized with recombinant gp160 and challenged with simian immunodeficiency virus. AIDS Res. Hum. Retroviruses 10:195-204.
3. Baba, T. W., Y. S. Jeong, D. Penninck, R. Bronson, M. F. Greene, and R. M. Ruprecht. Pathogenicity of live attenuated SIV after mucosal infection of neonatal macaques Science, in press.
4. Berglund, P., M. Quesada-Rolander, R. Thorstensson. P. Putkonen, G. Biberfeld, and P. Liljeström. 1995. Unpublished data.
5. Berglund, P., M. Sjoberg, H. Garoff, G. J. Atkins, B. J. Sheahan, and P. Liljeström. 1993. Semliki Forest virus expression system: production of conditionally infectious recombinant particles. Bio/Technology 11:916-920.
6. Berman, P. W., T. J. Gregory, L. Riddle, G. R. Nakamura, M. A. Champe, J. P. Porter, F. M. Wurm, R. D. Hershberg, E. K. Cobb, and J. W. Eichberg. 1990 Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160. Nature (London) 345:622-625
7. Coben, J. 1993 A new goal: preventing disease, not infection. Science 262:1820-1821.
8. Daniel, M. D., F. Kirchhoff, S. C. Czajak, P. K. Sehgal, and R. C. Desrosiers. 1992. Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science 258:1938-1941.
9. Daniel, M. D., G. P. Mazzara, M. A. Simon, P. K. Sehgal, T. Kodama, D. L. Panicali, and R. C. Desrosiers. 1994. High-tiler immune responses elicited by recombinant vaccinia virus particle boosting are ineffective in preventing virulent SIV infection. AIDS Res. Hum. Retroviruses 10:839-851.
10. Deen, K. C., J. S. McDougal, R. Inacker, G. Folena-Wasserman, J. Arthos, J. Rosenberg, P. J. Maddon, R. Axel, and R. W. Sweet. 1988. A soluble form of CD4 (T4) protein inhibits AIDS virus infection Nature (London) 331:82-84.
11. Dewhurst, S., J. E. Embretson. D. C. Anderson, J. I. Mullins, and P. N. Fultz. 1990. Sequence analysis and acute pathogenicity of molecularly cloned SIVsmm-PBj14, Nature (London) 345:636-640.
12. Emini, E. A., W. A. Schleif, J. H. Nunberg, A. J. Conley, Y. Eda, S. Tokiyoshi, S. D. Putney, S. Matsushita, K. E. Cobb, C. M. Jett, J. W. Eichberg, and K. K. Murthy. 1992 Prevention of HIV-1 infection in chimpanzees by gp120 V3 domain-specific monoclonal antibody. Nature (London) 355:728-730.
13. Federal Register. 1993. Addition of Appendix D-LX to the NIH Guidelines Regarding Semliki Forest Virus. Hum. Gene Ther 5:401.
14. Fultz, P. N., H. M. McClure, D. C. Anderson, and W. M. Switzer. 1989. Identification and biologic characterization of an acutely lethal variant of simian immunodeficiency virus from sooty mangabeys (SIV/SMM). AIDS Res. Hum. Retroviruses 5:397-409.
15. Fultz, P. N., and P. M. Zack. 1994. Unique lentivirus-host interactions: SIVsmmPBj14 infection of macaques. Virus Res. 32:205-225.
16. Gilljam, G. 1993. Envelope glycoproteins of HTV-1, HIV-2, and SIV purified with Galanthus nivalis agglutinin induce strong immune responses. AIDS Res. Hum. Retroviruses 9:431-438
17. Hart, M. K., T. J. Palker. T. J. Matthews, A. J. Langlois, N. W. Lerche, M. E. Martin, R. M. Scearce, C. McDanal, D. P. Bolognesi, and B. F. Haynes. 1990. Synthetic peptides containing T and B cell epitopes from human immunodeficiency virus envelope gp120 induce anti-HIV proliferative responses and high titers of neutralizing antibodies in rhesus monkeys. J. Immunol. 145:2677-2685.
18. Hirsch, V. M., S. Goldstein, N. A. Hynes, W. R. Elkins, W. T. London, P. M. Zack, D. Montefiori, and P. R. Johnson. 1994. Prolonged clinical latency and survival of macaques given a whole inactivated simian immunodeficiency virus vaccine J Infect Dis. 170:51-59.
19. Hu, S.-L., K. Abrams, G. N. Barber, P. Moran, J. M. Zarling, A. J. Langlois, L. Kuller, W. R. Morton, and R. E. Benveniste. 1992 Protection ot macaques against SIV infection by subunit vaccines of SIV envelope glycoprotein gp160. Science 255:456-459.
20. Hu, S.-L., K. Abrams, L. Misher, V. Stallard, P. Moran, J. M. Zarling, A. J. Langlois, L. Kuller, W. R. Morton, and R. E. Benveniste. 1992. Evaluation of protective efficacy of recombinant subunit vaccines against simian immunodeficiency virus infection of macaques. J. Med. Primatol. 21:119-125.
21. Israel, Z. R., G. A. Dean, D. H. Maul, S. P. O'Neil, M. J. Dreitz, J. I. Mullins, P. N. Fultz, and E. A. Hoover. 1993 Early pathogenesis of disease caused by SIVsmmPBj14 molecular clone 1 9 in macaques AIDS Res. Hum Retroviruses 9:277-285.
22. Israel, Z. R., P. F. Edmonson, D. H. Maul, S. P. O'Neil, S. P. Mossman, C. Thiriart, L. Fabry, O. Van Opstal, C. Bruck, F. Bex, A. Burny, P. N. Fultz, J. I. Mullins, and E. A. Hoover. 1994. Incomplete protection, but suppression of virus burden, elicited by subunit simian immunodeficiency virus vaccines. J. Virol. 68:1843-1853.
23. Johnston, M. I., J. S. Noe, and J. Y. Killen. 1994. Recent advances in AIDS vaccine research and development. AIDS Res. Hum. Retroviruses 10:S317-S323.
24. Lewis, M. G., W. R. Elkins, F. E. McCutchan, R. E. Benveniste, C. Y. Lai, D. C. Montefiori, D. S. Burke, G. A. Eddy, and A. Shafferman. 1993. Passively transferred antibodies directed against conserved regions of SIV envelope protect macaques from SIV infection. Vaccine 11:1347-1355.
25. Li, S., V. Polonis, H. Isobe, H. Zaghouani, R. Guinea, T. Moran, C. Bona, and P. Palese. 1993. Chimeric influenza virus induces neutralizing antibodies and cytotoxic T cells against human immunodeficiency virus type 1. J. Virol. 67:6659-6666.
26. Liljeström, P. 1994. Alphavirus expression systems. Curr. Opin. Biotechnol. 5:495-500.
27. Liljeström, P., and H. Garoff. 1991. A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Bio/Technology 9:1356-1361
28. Marthas, M. L., S. Sujipto, J. Higgins, B. Lohman, J. Torten, P. A. Luciw, P. A. Marx, and N. C. Pedersen. 1990. Immunization with a live, attenuated simian immunodeficiency virus (SIV) prevents early disease but not infection in rhesus macaques challenged with pathogenic SIV. J. Virol. 64:3694-3700.
29. Murphy-Corb, M., L. N. Martin, B. Davison-Fairbum, R. C. Montelaro, M. Miller, M. West, S. Ohkawa, G. B. Baskin, J.-Y. Zhang, S. D. Putney, A. C. Allison, and D. A. Eppstein. 1989. A formalin-inactivated whole SIV vaccine confers protection in macaques. Science 246:1293-1297.
30. Murphy-Corb, M., R. C. Montelaro, M. A. Miller, M. West, L. N. Martin, B. Davison-Fairbum, S. Ohkawa, G. B. Baskin, J.-Y. Zhang, S. D. Putney, A. C. Allison, and D. A. Eppstein. 1991. Efficacy of SIV/DeltaB670 glycoprotein-enriched and glycoprotein-depleted subunit vaccines in protecting against infection and disease in rhesus monkeys. AIDS 5:655-662.
31. Paul, N. L., M. Marsh, J. A. McKeating, T. F. Schulz, P. Liljeström, H. Garoff, and R. A. Weiss. 1993. Expression of HIV-1 envelope glycoprotein by Semliki Forest virus vectors. AIDS Res. Hum. Retroviruses 9:963-970.
32. Planelles, V., N. L. Haigwood, M. L. Marthas, K. A. Mann, C. Scandella, W. D. Lidster, J. R. Schuster, R. Van Kuyk, P. A. Marx, M. B. Gardner, et al. 1991. Functional and immunological characterization of SIV envelope protein produced in genetically engineered mammalian cells. AIDS Res. Hum. Retrovinises. 7:889-898.
33. Shafferman, A., P. B. Jahrling, R. E. Benveniste, M. G. Lewis, T. J. Phipps, F. Eden-McCutchan, J. Sadoff, G. A. Eddy, and D. S. Burke. 1991. Protection of macaques with a simian immunodeficiency virus envelope peptide based on conserved human immunodeficiency virus type 1 sequences Proc. Natl Acad. Sci. USA 88:7126-7130.
34. Shafferman, A., M. G. Lewis, F. E. McCutchan, R. E. Benveniste, P. B. Jahrling, R. L. Hickman, C. Y. Lai, D. S. Burke, and G. A. Eddy. 1992. Vaccination of macaques with SIV conserved peptides suppressed infection and prevented disease progression and transmission. AIDS Res. Hum. Retroviruses 8:1483-1487.
35. Shen, L., Z. W. Chen, M. D. Miller, V. Stallard, G. P. Mazzara, D. L. Panicali, and N. L. Letvin. 1991. Recombinant virus vaccine-induced SIV-specific CD8+ cytotoxic T lymphocytes. Science 252:440-443
36. Urlaub, G., and L. A. Chasin. 1980 Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity Proc. Natl. Acad. Sci USA 77:4216-4220.
37. Vaslin, B., R. Le Grand, G. Vogt, O. Benveniste, G. Gras, P. Roques, P. Stoeckel, P. L. Salk, J. Salk, and D. Dormont. 1994. Induction of humoral and cellular immunity to simian immunodeficiency virus: what are the requirements for protection? Vaccine 12:1132-1140.
38. Wigler, M., M. Perucho, D. Kurtz, A. Pellicer, R. Axel, and S. Siverstein. 1980. Transformation of mammalian cells with an amplifiable dominant-acting gene. Proc. Natl. Acad Sci. USA 77:3567-3570.
39. 38a.Wissink, J., and J. I. Mullins. Unpublished data
40. Yasutomi, Y., S. Koenig, R. M. Woods, J. Madsen, N. M. Wassef, C. R. Alving, H. J. Klein, T. E. Nolan, L. J. Boots, J. A. Kessler, E. A. Emini, A. J. Conley, and N. L. Letvin. 1995. A vaccine-elicited, single viral epitope-specific cytotoxic T-lymphocyte response does not protect against intravenous, cell-free simian immunodeficiency virus challenge. J. Virol. 69:2279-2284.
41. Zhou, X., P. Berglund, G. Rhodes, S. E. Parker, M. Jondal, and P. Liljeström. 1994. Self-replicating Semliki Forest virus RNA as recombinant vaccine. Vaccine 12:1510-1514.
42. Zhou, X., P. Berglund, H. Zhao, P. Liljeström, and M. Jondal. 1995. Generation of cytotoxic and humoral immune responses using non-replicative recombinant Semliki Forest virus. Proc. Natl. Acad. Sci. USA 92:3009-3013