Immunological basis for protection in a murine model of tick-borne encephalitis by a recombinant adenovirus carrying the gene encoding the NS1 non-structural protein

Journal of General Virology

Volumn 79, Issue 4, 1998, Pages 689-695

  Timofeev, A V ^a   Ozherelkov, S V ^a   Pronin, A V ^b   Deeva, A V ^b   Karganova, G G ^a   Elbert, L B ^a   Stephenson, J R ^c  

^a CHUMAKOV INSTITUTE OF POLIOMYELITIS AND VIRAL ENCEPHALITIDES   (Russian Federation)

^b GAMALEYA RESEARCH INSTITUTE OF EPIDEMIOLOGY AND MICROBIOLOGY   (Russian Federation)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; ENVELOPE PROTEIN; GLYCOSYLATED PROTEIN;

ADENOVIRUS; ANIMAL; ARTICLE; B LYMPHOCYTE; GENE EXPRESSION; HELPER CELL; IMMUNE RESPONSE; IMMUNITY; PRIORITY JOURNAL; TICK BORNE ENCEPHALITIS; TICK BORNE ENCEPHALITIS FLAVIVIRUS; VACCINATION;

EID: 0031926451     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-79-4-689     Document Type: Article

References (45)

1. Abbas, A. K., Murphy, K. M. & Sher, A. (1996). Functional diversity of helper T lymphocytes. Nature 383, 787-793.
2. Beutler, B. & Cerami, A. (1989). The biology of cachectin/TNF - a primary mediator of host response. Annual Review of Immunology 7, 625-655.
3. + human cytotoxic T cells. Journal of Virology 63, 5086-5091.
4. Cambell, I., Greenbear, T. & Kochmann, M. A. (1975). Macrophage reduction assay for human and mouse interferon. Canadian Journal of Microbiology 21, 1247-1253.
5. Cardiff, R. D., McCloud, T. G. & Russell, P. K. (1970). Molecular size and charge relationships of the soluble complement-fixing antigens of dengue virus. Virology 41, 569-572.
6. Chambers, T. J., Hahn, C. S., Galler, R. & Rice, C. M. (1990). Flavivirus genome organisation, expression and replication. Annual Review of Microbiology 44, 649-688.
7. Coffman, R. L., Lebman, D. A. & Rothman, P. (1993). Mechanisms and regulation of immunoglobulin isotype switching. Advances in Immunology 54, 229-270.
8. Dzhivanyan, T. I., Korolev, M. V., Karganova, G. G., Lisak, V. M., Kashyanova, G. M. & Chuprinskaya, M. V. (1988). Changes in host-dependent characteristics of tick-borne encephalitis virus upon its adaptation to ticks and re-adaptation to white mice. Voprosi Virusologii 5, 589-595.
9. Falker, W. A., Jr, Diwan, A. R. & Halstead, S. B. (1973). Human antibody to dengue soluble-complement fixing (SCF) antigens. Journal of Immunology 111, 1804-1809.
10. Fooks, A. R., Schadeck, E., Leibert, U. G., Dowsett, A. B., Rima, B. K., Steward, M. W., Stephenson, J. R. & Wilkinson, G. W. G. (1995). High level expression of the measles virus nucleocapsid protein by using a replication-deficient adenovirus vector: induction of an MHC-I-restricted CTL response and protection in a murine model. Virology 210, 456-465.
11. Gould, E. A., Buckley, A., Barrett, A. D. T. & Cammack, N. (1986). Neutralizing (54K) and non-neutralizing (54K and 48K) monoclonal antibodies against structural and non-structural yellow fever virus proteins confer immunity in mice. Journal of General Virology 67, 591-595.
12. Graham, F. L. & Prevec, L. (1992). Adenovirus-based expression vectors and recombinant vaccine. In Biotechnology, vol. 20, Vaccines, New Approaches to Immunological Problems, pp. 363-390. Edited by R. W. Ellis. Boston: Butterworth-Heinemann.
13. Hall, R. A., Brand, T. N. H., Lobigs, H., Sangster, M. Y., Howard, M. J. & Mackenzie, J. S. (1996). Protective immune response to the E and NS1 proteins of Murray Valley encephalitis virus in hybrids of flavivirus-resistant mice. Journal of General Virology 77, 1287-1294.
14. Halstead, S. B. (1979). In vivo enhancement of dengue virus infection in rhesus monkeys by passively transferred antibody. Journal of Infectious Diseases 140, 527-533.
15. Halstead, S. B. (1982). Immune enhancement of viral infection. Progress in Allergy 31, 301-364.
16. Hambleton, P., Stephenson, J. R., Baskerville, A. & Wiblin, C. N. (1983). Pathogenesis and immune response of vaccinated and unvaccinated rhesus monkeys to TBEV. Infection and Immunity 40, 995-1003.
17. Henry, C. (1980). Cell separation. In Selected Methods in Cellular Immunology, pp. 182-194. Edited by S. F. B. Michal. Location of publisher: Freeman Corporation.
18. Holzmann, H., Vorobyova, M. S., Lodyzhenskaya, I. R., Ferenci, K., Kundi, M., Kunz, C. & Heinz, F. X. (1992). Molecular epidemiology of tick-borne encephalitis virus: cross-protection between European and Far-eastern subtypes. Vaccine 10, 345-349.
19. Jacobs, S. C., Wilkinson, G. W. G. & Stephenson, J. R. (1992). High level expression of TBEV NS1 protein by using an adenovirus-based vector: protection elicited in a murine model. Journal of Virology 66, 2086-2095.
20. Jacobs, S. C., Stephenson, J. R. & Wilkinson, G. W. G. (1993). Sequence of the NSl protein gene of the K23 isolate of TBEV and identification of conserved motifs. Archives of Virology 129, 279-285.
21. Jacobs, S. C., Stephenson, J. R. & Wilkinson, G. W. G. (1994). Protection elicited by a replication-defective adenovirus vector expressing the tick-borne encephalitis virus non-structural glycoprotein NS1. Journal of General Virology 75, 2399-2402.
22. Kaufmann, S. H. E. (1993). Immunity to intracellular bacteria. Annual Review of Immunology 11, 129-163.
23. Klockmann, U., Krivanec, K., Stephenson, J. R. & Hilfenhaus, J. (1991). Protection against European isolates of tick-borne encephalitis virus after vaccination with a new tick-borne encephalitis vaccine. Vaccine 9, 210-212.
24. Krasilnikov, I. V., Elbert, L. B., Khanina, M. K. & Sobolev, S. G. (1984). Comparative study of infectious and formaldehyde-inactivated tickborne encephalitis virus particles. Archives of Virology 79, 241-253.
25. Kurane, I., Meager, A. & Ennis, F. A. (1989). Dengue virus-specific human T cell clones. Serotype crossreactive proliferation, interferon gamma production and cytotoxic activity. Journal of Experimental Medicine 170, 763-775.
26. + cytotoxic T cell clones: multiple patterns of virus cross-reactivity recognized by NS3-specific T-cell clones. Journal of Virology 65, 1825-1828.
27. Lobigs, M., Arthur, C. E., Muellbacher, A. & Blanden, R. V. (1994). The flavivirus non-structural protein NS3 is a dominant source of cytotoxic T cell peptide determinants. Virology 202, 195-201.
28. Parrish, C. L., Coa, G., Hill, A., Muellbacher, A., Westaway, E. G. & Blanden, R. V. (1991). Preliminary analysis of murine cytotoxic T cell responses to the proteins of the flavivirus Kunjin using vaccinia virus expression. Journal of General Virology 72, 1645-1653.
29. Peiris, J. S. M. & Porterfield, J. S. (1982). Antibody-dependent enhancement: its antigenic specificity in relation to Togaviridae. Journal of General Virology 58, 291-296.
30. Phillpotts, R. J., Stephenson, J. R. & Porterfield, J. S. (1985). Antibody-dependent enhancement of tick-borne encephalitis virus infectivity. Journal of General Virology 66, 1831-1837.
31. Reed, L. J. & Muench, H. (1938). A simple method of estimating fifty per cent endpoints. American Journal of Hygiene 27, 493-497.
32. Robbins, D. S., Shirazi, Y., Drysdale, B. E., Lieberman, A., Shin, H. S. & Shin, M. L. (1987). Production of cytotoxic factor for oligodendrocytes by stimulated astrocyres. Journal of Immunology 139, 2593-2597.
33. + cytotoxic lymphocytes. Journal of Virology 67, 801-806.
34. Rubin, R. A. & Rourke, L. B. (1994). Adenovirus vaccines. In Vaccines, 2nd edn, pp. 475-501. Edited by S. A. Plotkin & E. A. Mortimer. Philadelphia: Saunders.
35. Ruff, M. R. & Gifford, G. I. (1981). Tumor necrosis factor. In Lymphokines, vol. II, pp 235-272. Edited by I. Pick. New York: Academic Press.
36. Schlesinger, J. J., Brandiss, M. W. & Walsh, E. E. (1985). Protection against yellow fever 27D encephalitis in mice by passive transfer of monoclonal antibodies to the non-structural glycoprotein gp48 and by active immunization with gp48. Journal of Immunology T35, 2805-2809.
37. Schlesinger, J. J., Brandriss, M. W., Cropp, C. B. & Monath, T. P. (1986). Protection against yellow fever in monkeys by immunization with yellow fever non-structural protein 1. Virology 60, 1153-1155.
38. Schwartz, A. R., Togo, Y. & Hornick, R. B. (1974). Clinical evaluation of live, oral types 1, 2 and 5 adenovirus vaccines. American Review of Respiratory Disease 109, 233-238.
39. Spies, J. M., Westland, K. W., Bonner, J. G. & Pollard, J. D. (1995). Intraneural activated T-cells cause focal break-down of the blood-nerve barrier. Brain 118, 857-868.
40. Stephenson, J. R. (1988). Flavivirus vaccines. Vaccine 6, 471-480.
41. Stephenson, J. R., Wilton-Smith, P. & Lee, J. M. (1984). Antigenic variation among members of the tick-borne encephalitis complex. Journal of General Virology 65, 81-89.
42. Venugopal, K., Buckley, A., Reid, H. W. & Gould, E. A. (1992). Nucleotide sequence of the envelope glycoprotein of Negishi virus shows very close homology to louping ill virus. Virology 190, 515-521.
43. Warnes, A., Walkland, A. & Stephenson, J. R. (1986). Development of an ELISA assay for staphylococcal protein A produced in E. coli by pUC8 based plasmids containing the S. aureus Cowan 1 protein A gene. Journal of Immunological Methods 93, 63-70.
44. Wilkinson, G. W. G. & Akrigg, A. (1992). Constitutive and enhanced expression from the CMV major IE promoter in a defective adenovirus vector. Nucleic Acids Research 20, 2233-2239.
45. Wilkinson, G. W. G. & Borysiewicz, L. K. (1995). Gene therapy and viral vaccination: the interface. British Medical Bulletin 51, 205-216.