Dna-based and alphavirus-vectored immunisation with PrM and E proteins elicits long-lived and protective immunity against the flavivirus, Murray Valley encephalitis virus

Virology

Volumn 250, Issue 1, 1998, Pages 151-163

  Colombage, G ^a   Hall, R ^b   Pavy, M ^a   Lobigs, M ^a  

^a Biology and Environment   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS PROTEIN;

ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; FLAVIVIRUS; HUMORAL IMMUNITY; IMMUNIZATION; IMMUNOGENICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIRUS IMMUNITY; VIRUS INFECTIVITY; VIRUS NEUTRALIZATION; VIRUS REPLICATION;

ALPHAVIRUS; ANIMALIA; FLAVIVIRUS; MURRAY VALLEY ENCEPHALITIS VIRUS; RNA VIRUSES; SEMLIKI FOREST VIRUS;

EID: 0032505578     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1998.9357     Document Type: Article

References (64)

1. Allison S. L., Stadler K., Mandl C. W., Kunz C., Heinz F. X. Synthesis and secretion of recombinant tick-borne encephalitis virus protein E in soluble and particulate form. J. Virol. 69:1995;5816-5820.
2. Amberg S. M., Nestorowicz A., McCourt D. W., Rice C. M. NS2B-3 proteinase-mediated processing in the yellow fever virus structural region:in vitroin vivo. J. Virol. 68:1994;3794-3802.
3. Boyle J. S., Koniaras C., Lew A. M. Influence of cellular location of expressed antigen on the efficacy of DNA vaccination: cytotoxic T lymphocyte and antibody responses are suboptimal when antigen is cytoplasmic after intramuscular DNA vaccination. Int. Immunol. 9:1997;1897-1906.
4. Brandt W. E. Current approaches to the development of dengue vaccines and related aspects of the molecular biology of flaviviruses. J. Inf. Dis. 157:1988;1105-1111.
5. Bray M., Lai C.-J. Dengue virus premembrane and membrane proteins elicit a protective immune response. Virology. 185:1991;505-508.
6. Chambers T. J., Hahn C., Galler R., Rice C. M. Flavivirus genome organization, expression, and replication. Annu. Rev. Microbiol. 44:1990;649-688.
7. Coutelier J.-P., van der Logt J. T. M., Heessen F. W. A., Warnier G., van Snick J. IgG2a restriction of murine antibodies elicited by viral infections. J. Exp. Med. 165:1987;64-69.
8. Dalgarno L., Trent D. W., Strauss J. H., Rice C. M. Partial nucleotide sequence of the Murray Valley encephalitis virus genome. J. Mol. Biol. 187:1986;309-323.
9. Donnelly J. J., Ulmer J. B., Liu M. A. DNA vaccines. Life Sci. 60:1997;163-172.
10. Ertl H. C. J., Xiang Z. Q. Genetic Immunization. Viral Immunol. 9:1996;1-9.
11. Falgout B., Bray M., Schlesinger J. J., Lai C.-J. Immunization of mice with recombinant vaccinia virus expressing authentic dengue virus nonstructural protein NS1 protects against lethal dengue virus encephalitis. J. Virol. 64:1990;4356-4363.
12. Feltquate D. M., Heaney S., Webster R. G., Robinson H. L. Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization. J. Immunol. 158:1997;2278-2284.
13. French E. L. Murray Valley encephalitis: isolation and characterization of the aetological agent. Med. J. Aust. 1:1952;100-103.
14. Frolov I., Hoffman T. A., Pragai B. M., Dryga S. A., Huang H. V., Schlesinger S., Rice C. M. Alphavirus-based expression vectors: strategies and applications. Proc. Natl. Acad. Sci. USA. 93:1996;11371-11377.
15. Fynan E. F., Webster R. G., Fuller D. H., Haynes J. R., Santoro J. C., Robinson H. L. DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations. Proc. Natl. Acad. Sci. USA. 90:1993;11478-11482.
16. Gould E. A., Buckley A., Barrett A. D. T., Cammack N. Neutralizing (54 K) and non-neutralizing (54 K and 48 K) monoclonal antibodies against structural and non-structural yellow fever virus proteins confer immunity in mice. J. Gen. Virol. 67:1986;591-596.
17. Hall R. A., Brand T. N. H., Lobigs M., Sangster M. Y., Howard M. J., Mackenzie J. S. Protective immune responses to the E and NS1 proteins of Murray Valley encephalitis virus in hybrids of flavivirus-resistant mice. J. Gen. Virol. 77:1996;1287-1294.
18. Hall R. A., Kay B. H., Burgess G. W., Clancy P., Fanning I. D. Epitope analysis of the envelope and non-structural glycoproteins of Murray Valley encephalitis virus. J. Gen. Virol. 71:1990;2923-2930.
19. Hawkes R. A., Roehrig J. T., Hunt A. R., Moore G. A. Antigenic structure of the Murray Valley encephalitis virus E glycoprotein. J. Gen. Virol. 69:1988;1105-1109.
20. Hill A. B., Lobigs M., Blanden R. V., Kulkarni A. B., Müllbacher A. The cellular immune response to flaviviruses. Viruses and the cellular immune response. 1993;Marcel Dekker, New York. p. 389-428.
21. Hocart M. J., Mackenzie J. S., Stewart G. A. The immunoglobulin G subclass responses of mice to influenza A virus: the effect of mouse strain, and the neutralizing abilities of individual protein A-purified subclass antibodies. J. Gen. Virol. 70:1989;2439-2448.
22. Jakobs S. C., Stephenson J. R., Wilkinson G. W. G. High-level expression of the tick-borne encephalitis virus NS1 proteins by using an adenovirus-based vector: protection elicited in a murine model. J. Virol. 66:1992;2086-2095.
23. Jakobs S. C., Stephenson J. R., Wilkinson G. W. G. Protection elicited by a replication-defective adenovirus vector expressing the tick-borne encephalitis virus non-structural glycoprotein NS1. J. Gen. Virol. 75:1994;2399-2402.
24. Justewicz D. M., Webster R. G. Long-term maintenance of B cell immunity to influenza virus hemagglutininin in mice following DNA-based immunisation. Virology. 224:1996;10-17.
25. Kimura-Kuroda J., Yasui K. Protection of mice against Japanese encephalitis virus by passive administration of monoclonal antibodies. J.Immunol. 141:1988;3606-3610.
26. Konishi E., Mason P. W. Proper maturation of the Japanese encephalitis virus envelope glycoprotein requires cosynthesis of the premembrane protein. J. Virol. 67:1993;1672-1675.
27. Konishi E., Pincus S., Paoletti E., Shope R. E., Burrage T., Mason P. W. Mice immunized with a subviral particle containing the Japanese encephalitis virus prM/M and E proteins are protected from lethal JEV infection. Virology. 188:1992;714-720.
28. Krieg A. M., Yi A.-K., Matson S., T. J. W., Bishop G. A., Teasdale R., Koretzky G. A., Klinman D. M. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature. 374:1995;546-549.
29. Leclerc C., Deriaud E., Rojas M., Whalen R. G. The preferential induction of a Th1 immune response by DNA-based immunization is mediated by the immunostimulatory effect of plasmid DNA. Cell. Immunol. 179:1997;97-106.
30. Liljeström P., Lusa S., Huylebroeck D., Garoff H. In vitro. J. Virol. 65:1991;4107-4113.
31. Lin Y.-L., Chen L.-K., Liao C.-L., Yeh C.-T., Ma S.-H., Chen J.-L., Huang Y.-L., Chen S.-S., Chiang H. Y. DNA immunization with Japanese encephalitis virus nonstructural protein NS1 elicits protective immunity in mice. J. Virol. 72:1998;191-200.
32. Lobigs M. Proteolytic processing of a Murray Valley encephalitis virus non-structural polyprotein segment containing the viral proteinase: accumulation of a NS3-4A precursor which requires mature NS3 for efficient processing. J. Gen. Virol. 73:1992;2305-2312.
33. Lobigs M. Flavivirus premembrane protein cleavage and spike heterodimer secretion require the function of the viral proteinase NS3. Proc. Natl. Acad. Sci. 90:1993;6218-6222.
34. Lobigs M., Arthur C. E., Müllbacher A., Blanden R. V. The flavivirus nonstructural protein, NS3, is a dominant source of cytotoxic T cell peptide determinants. Virology. 202:1994;195-201.
35. +. Arbovirus Res. Australia. 7:1997;160-165.
36. Michel M.-L., Davis H. L., Schleef M., Mancini M., Tiollais P., Whalen R. G. DNA-mediated immunization to the hepatitis B surface antigen in mice: aspects of the humoral response mimic hepatitis B virus infection in humans. Proc. Natl. Acad. Sci. USA. 92:1995;5307-5311.
37. Monath T. P. Dengue: the risk to developed and developing countries. Proc. Natl. Acad. Sci. USA. 91:1994;2395-2400.
38. Monath T. P., Heinz F. X. Flaviviruses. N .Fields B., Knipe D. M., Howley P. M., Chanock R. M., Melnick J. L., Monath T. P., Roizman B., Strauss S. E. Fields Virology. 1996;961-1034 Lippincott-Raven, Philadelphia.
39. Mossman S. P., Bex F., Berglund P., Arthos J., O'Neil S. P., Riley D., Maul D. H., Bruck C., Momin P., Burny A., Fultz P. N., Mullins J. I., Liljeström P., Hoover E. A. Protection against lethal simian immunodeficiency virus SIVsmmPBj14 disease by a recombinant Semliki Forest virus gp160 vaccine and by a gp120 subunit vaccine. J. Virol. 70:1996;1953-1960.
40. Pertmer T. M., Roberts T. R., Haynes J. R. Influenza virus nucleoprotein-specific immunoglobulin G subclass and cytokine responses elicited by DNA vaccination are dependent on the route of vector DNA delivery. J. Virol. 70:1996;6119-6125.
41. Phillpotts R. J., Venogopal K., Brooks T. Immunisation with DNA polynucleotides protects mice against lethal challenge with St. Louis encephalitis virus. Arch. Virol. 141:1996;743-749.
42. Pincus S., Mason P. W., Konishi E., Fonseca B. A. L., Shope R. E., Rice C. M., Paoletti E. Recombinant vaccinia virus producing the prM and E proteins of yellow fever virus protects mice from lethal Yellow Fever encephalitis. Virology. 187:1992;290-297.
43. Pushko P., Parker M., Ludwig G. V., Davis N. L., Johnston R. E., Smith J. F. Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genesin vitroin vivo. Virology. 239:1997;389-401.
44. Putnak J. R., Schlesinger J. J. Protection of mice against yellow fever virus encephalitis by immunization with a vaccinia virus recombinant encoding the yellow fever virus nonstructural proteins, NS1, NS2a and NS2b. J. Gen. Virol. 71:1990;1697-1702.
45. Raz E., Carson D. A., Parker S. E., Parr T. B., Abai A. M., Aichinger G., Gromkowski S. H., Singh M., Lew D., Yankauckas M. A., Baird S. M., Rhodes G. H. Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses. Proc. Natl. Acad. Sci. USA. 91:1994;9519-9523.
46. Rice C. M. Flaviviridae. Fields B. N., Knipe D. M., Howley P. M., Chanock R. M., Melnick J. L., Monath T. P., Roizman B., Strauss S. E. Fields Virology. 1996;931-959 Lippincott-Raven, Philadelphia.
47. Roman M., Martin-Orozco E., Goodman J. S., Nguyen M.-D., Sato Y., Ronaghy A., Kornbluth R. S., Richman D. D., Carson D. A., Raz E. Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants. Nat. Med. 3:1997;849-854.
48. ++. J. Virol. 70:1996;6540-6546.
49. +. J. Virol. 67:1993;801-806.
50. Sangster M. Y., Urosevic N., Mansfield J. P., Mackenzie J. S., Shellam G. R. Mapping of the Flv locus controlling resistance to flaviviruses on mouse chromosome 5. J. Virol. 68:1994;448-452.
51. Sato T., Takamura C., Yasuda A., Miyamoto M., Kamogawa K., Yasui K. High-level expression of the Japanese encephalitis virus E protein by recombinant vaccinia virus and enhancement of its extracellular release by the NS3 gene product. Virology. 192:1993;483-490.
52. Sato Y., Roman M., Tighe H., Lee D., Corr M., Nguyen M.-D., Silverman G. J., Lotz M., Carson D. A., Raz E. Immunostimulatory DNA sequences necessary for efficient intradermal gene immunisation. Science. 273:1996;352-354.
53. Schalich J., Allison S. L., Stiasny K., Mandl C. W., Kunz C., Heinz F. X. Recombinant subviral particles from tick-borne encephalitis virus are fusogenic and provide a model system for studying flavivirus envelope glycoprotein functions. J. Virol. 70:1996;4549-4557.
54. Schlesinger J. J., Brandriss M. W., Walsh E. E. Protection against 17D yellow fever encephalitis in mice by passive transfer of monoclonal antibodies to the nonstructural glycoprotein gp48 and by active immunization with gp48. J. Immunol. 135:1985;2805-2809.
55. Smaljohn C., Vanderzanden L., Bray M., Custer D., Meyer B., Li D., Rossi C., Fuller D., Fuller J., Haynes J., Huggins J. Naked DNA vaccines expressing the prM and E genes of Russian spring summer encephalitis virus and Central European encephalitis virus protect mice from homologous and heterologous challenge. J. Virol. 71:1997;9563-9569.
56. Smucny J. J., Kelly E. P., Macarthy O., King A. D. Murine immunoglobulin G subclass responses following immunization with live dengue virus or a recombinant dengue protein. Am. J. Trop. Med. Hyg. 53:1995;432-437.
57. Stocks C. E., Lobigs M. Signal peptidase cleavage at the flavivirus C-prM junction: dependence on the viral NS2B-3 protease for efficient processing requires determinants in C, the signal peptide, and prM. J. Virol. 72:1998;2141-2149.
58. Ulmer J. B., Donnelly J. J., Parker S. E., Rhodes G. H., Felgner P. L., Dwarki V. J., Gromkowski S. H., Randall Deck R., DeWitt C. M., Friedman A., Hawe L. A., Leander K. R., Martinez D., Perry H. C., Shiver J. W., Montgomery D. L., Liu M. A. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science. 259:1993;1745-1749.
59. Ulmer J. B., Sadoff J. C., Liu M. A. DNA vaccines. Curr. Opin. Immunol. 8:1996;531-536.
60. Whalen R. G. DNA vaccines, cyberspace, and self-help programs. Intervirology. 39:1996;120-125.
61. Xiang Z. Q., Spitalnik S. L., Cheng J., Erikson J., Wojczyk B., Ertl H. C. J. Immune responses to nucleic acid vaccines to rabies virus. Virology. 209:1995;569-579.
62. Yamshchikov V. F., Compans R. W. Regulation of the late events in flavivirus protein processing and maturation. Virology. 192:1993;38-51.
63. Yasuda A., Kimura-Kuroda J., Ogimoto M., Miyamoto M., Sata T., Sato T., Takamura C., Kurata T., Kojima A., Yasui K. Induction of protective immunity in animals vaccinated with recombinant vaccinia viruses that express PreM and E glycoproteins of Japanese encephalitis virus. J. Virol. 64:1990;2788-2795.
64. Zhou X., Berglund P., Zhao H., Liljestrom P., Jondal M. Generation of cytotoxic and humoral immune responses by nonreplicative recombinant Semliki Forest virus. Proc. Natl. Acad. Sci. USA. 92:1995;3009-3013.