Lymphocytes from mice chronically infected with Theiler's murine encephalomyelitis virus produce demyelination of organotypic cultures after stimulation with the major encephalitogenic epitope of myelin proteolipid protein. Epitope spreading in TMEV infection has functional activity

Journal of Neuroimmunology

Volumn 104, Issue 1, 2000, Pages 79-84

  Dal Canto, Mauro C ^a   Calenoff, Miriam A ^a   Miller, Stephen D ^a   Vanderlugt, Carol L ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Demyelination; Epitope spreading; Multiple sclerosis; Proteolipid protein (PLP); Theiler's murine encephalomyelitis virus (TMEV)

Indexed keywords

CD4 ANTIGEN; EPITOPE; MYELIN; PROTEOLIPID PROTEIN;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; DELAYED HYPERSENSITIVITY; DEMYELINATION; HELPER CELL; IMMUNE MEDIATED INJURY; INFLAMMATION; MOUSE; MULTIPLE SCLEROSIS; MURINE ENCEPHALOMYELITIS VIRUS; NERVE CELL CULTURE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD; T LYMPHOCYTE SUBPOPULATION; VIRUS INFECTION;

ANIMALS; CARDIOVIRUS INFECTIONS; CELLS, CULTURED; CHRONIC DISEASE; DEMYELINATING DISEASES; ENCEPHALITIS; EPITOPES; IMMUNIZATION; LYMPHOCYTES; MICE; MICE, INBRED STRAINS; MYELIN BASIC PROTEINS; MYELIN PROTEOLIPID PROTEIN; MYELIN SHEATH; ORGAN CULTURE TECHNIQUES; OVALBUMIN; THEILOVIRUS;

EID: 0033963940     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(99)00230-1     Document Type: Article

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