The pathogenesis of postinfectious myocarditis

Clinical Immunology and Immunopathology

Volumn 80, Issue 3 II, 1996, Pages

  Rose, Noel R ^a,b   Hill, Susan L ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b Department of Molecular Microbiology and Immunology ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1; MYOSIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; AUTOIMMUNITY; CONFERENCE PAPER; CONTROLLED STUDY; COXSACKIE VIRUS B3; ETIOLOGY; EXPERIMENTAL MODEL; IMMUNE MEDIATED INJURY; MOUSE; MYOCARDITIS; NONHUMAN; PRIORITY JOURNAL;

EID: 0029846499     PISSN: 00901229     EISSN: None     Source Type: Journal    
DOI: 10.1006/clin.1996.0146     Document Type: Conference Paper

References (51)

1. 3 marine myocarditis: A pathologic spectrum of myocarditis in genetically defined inbred strains. J. Am. Coll. Cardiol. 9, 1311-1319, 1987.
2. Rose, N. R., Neumann, D. A., and Herskowitz, A., Coxsackievirus myocarditis. In "Advances in Internal Medicine" (G. H. Stollerman, J. T. LaMont, J. J. Leonard, and M. D. Siperstein, Eds.), Vol. 37, pp. 411-429, Mosby-Year Book, St. Louis, MO, 1992.
3. Neumann, D. A., Burek, C. L., Baughman, K. L., Rose, N. R., and Herskowitz, A., Circulating heart-reactive antibodies in patients with myocarditis or cardiomyopathy. J. Am. Coll. Cardiol. 16, 839-846, 1990.
4. 2+ current in isolated cardiac myocytes. Am. J. Physiol. 255, H960-H964, 1988.
5. Limas, C. J., Goldenberg, I. F., and Limas, C., Autoantibodies against beta-adrenoceptors in human idiopathic dilated cardiomyopathy. Circ. Res. 64, 97-103, 1989.
6. Schulze, K., Becker, B. F., Schauer, R., and Schultheiss, H.-P., Antibodies to ADP-ATP carrier - an autoantigen in myocarditis and dilated cardiomyopathy - impair cardiac function. Circulation 81, 959-969, 1990.
7. Schultheiss, H.-P., and Boite, H. D., Immunological analysis of autoantibodies against the adenine nucleotide translocator in dilated cardiomyopathy. J. Mol. Cell. Cardiol. 17, 603-617, 1985.
8. Latham, R. D., Mulrow, J. P., Virmani, R., Robinowitz, M., and Moody, J. M., Recently diagnosed idiopathic dilated cardiomyopathy: Incidence of myocarditis and efficacy of prednisone therapy. Am. Heart J. 117, 876-882, 1989.
9. Ulrich, G., Kühl, U., Melzner, B., Janda, I., Schäfer, B., and Schultheiss, H.-P., Antibodies against the adenosine di-triphosphate carrier cross-react with the Ca channel-functional and biochemical data. In "New Concepts in Viral Heart Disease" (H.-P. Schultheiss, Ed.), pp. 225-235, Springer-Verlag, Berlin, 1988.
10. Schultheiss, H.-P., The significance of autoantibodies against the ADP/ATP carrier for the pathogenesis of myocarditis and dilated cardiomyopathy - Clinical and experimental data. In "Springer Seminars in Immunopathology," Vol. 11, pp. 15-30, Springer-Verlag, Berlin, 1989.
11. Schulze, K., Becker, B. F., and Schultheiss, H.-P., Antibodies to the ADP-ATP carrier, an autoantigen in myocarditis and dilated cardiomyopathy, penetrate into myocardial cells and disturb energy metabolism in vivo. Circ. Res. 64, 179-192, 1989.
12. Ansari, A. A., Wang, Y.-C., Danner, D. J., Gravanis, M. B., Mayne, A., Neckelmann, N., Sell, K. W., and Herskowitz, A., Abnormal expression of histocompatibility and mitochondrial antigens by cardiac tissue from patients with myocarditis and dilated cardiomyopathy. Am. J. Pathol. 139, 337-354, 1991.
13. Limas, C. J., Limas, C., Kubo, S. H., and Olivari, M. T., Anti-beta-receptor antibodies in human dilated cardiomyopathy and correlation with HLA-DR antigens. Am. J. Cardiol. 65, 483-487, 1990.
14. Limas, C. J., and Limas, C., In "New Concepts in Viral Heart Disease" (H.-P. Schultheiss, Ed.), pp. 217-224, Springer-Verlag, Berlin, 1988.
15. Anderson, J. L., Carlquist, J. F., Lutz, J. R., DeWitt, C. W., and Hammond, E. H., HLA A, B, and DR typing in idiopathic dilated cardiomyopathy: A search for immune response factors. Am. J. Cardiol. 53, 1326-1330, 1984.
16. Mason, J. W., O'Connell, J. B., Herskowitz, A., Rose, N. R., McManus, B. M., Billingham, M. E., Moon, T. E., and the Myocarditis Treatment Trial Investigators, A clinical trial of immunosuppressive therapy for myocarditis. N. Engl. J. Med. 333, 269-275, 1995.
17. Godman, G. C., Bunting, H., and Melnick, J. L., The histopathology of coxsackievirus infection in mice. I. Morphologic observations with four different viral types. Am. J. Pathol. 28, 223-258, 1952.
18. Gromdus, E. I., and Dempster, G., Myocarditis in experimental coxsackievirus B3 infection. Can. J. Microbiol. 5, 605-615, 1959.
19. Woodruff, J. F., and Woodruff, J. J., Involvement of T lymphocytes in the pathogenesis of Coxsackievirus B3 heart disease. J. Immunol. 113, 1726-1734, 1974.
20. Hashimoto, I., and Komatsu, T., Myocardial changes after infection with Coxsackievirus B3 in nude mice. Br. J. Exp. Pathol. 59, 13-20, 1978.
21. Hashimoto, I., Tatsumi, M., and Nakagawa, M., The role of T lymphocytes in the pathogenesis of Coxsackievirus B3 heart disease. Br. J. Exp. Pathol. 64, 497-504, 1983.
22. Woodruff, J. F., Viral myocarditis. A review. Am. J. Pathol. 101, 427-479, 1980.
23. Gauntt, C. J., Gomez, P. T., Duffey, P. S., Grant, J. A., Trent, D. W., Witherspoon, S. M., and Prave, R. E., Characterization and myocarditic capabilities of Coxsackievirus B3 variants in selected mouse strains. J. Virol. 52, 598-605, 1984.
24. Wolfgram, L. J., Beisel, K. W., Herskowitz, A., and Rose, N. R., Variations in the susceptibility to Coxsackievirus B3-induced myocarditis among different strains of mice. J. Immunol. 136, 1846-1852, 1986.
25. Wolfgram, L. J., Beisel, K. W., and Rose, N. R., Heart-specific autoantibodies following murine Coxsackievirus B3 myocarditis. J. Exp. Med. 161, 1112-1121, 1985.
26. Alvarez, F. L., Neu, N., Rose, N. R., Craig, S. W., and Beisel, K. W., Heart-specific autoantibodies induced by Coxsackievirus B3: Identification of heart autoantigens. Clin. Immunol. Immunopathol. 43, 129-139, 1987.
27. Rose, N. R., Wolfgram, L. J., Herskowitz, A., and Beisel, K. W., Postinfectious autoimmunity: Two distinct phases of Coxsackievirus B3 induced myocarditis. Ann. N.Y. Acad. Sci. 475, 146-156, 1986.
28. Neumann, D. A., Lane, J. R., Lafond-Walker, A., Allen, G. S., Frondoza, C., Herskowitz, A., and Rose, N. R., Elution of autoantibodies from the hearts of coxsackievirus-infected mice. Eur. Heart. J. 12, 113-116, 1991.
29. Rose, N. R., Hill, S. L., and Neumann, D. A., Experimental myocarditis. In "Autoimmune Disease Models: A Guidebook" (C. A. Miller, Ed.), pp. 175-189, Academic Press, San Diego, 1994.
30. O'Donoghue, H. L., Lawson, C. M., and Reed, W. D., Autoantibodies to cardiac myosin in mouse cytomegalovirus myocarditis. Immunology 71, 20-28, 1990.
31. Price, P., Eddy, K. S., Papadimitriou, J. M., Faulkner, D. L., and Shellam, G. R., Genetic determination of cytomegalovirus-induced and age-related cardiopathy in inbred mice. Characterization of infiltrating cells. Am. J. Pathol. 138, 59-67, 1991.
32. Neu, N., Rose, N. R., Beisel, K. W., Herskowitz, A., Gurri-Glass, G., and Craig, S. W., Cardiac myosin induces myocarditis in genetically predisposed mice. J. Immunol. 139, 3630-3636, 1987.
33. Neumann, D. A., Lane, J. R., Wulff, S. M., Allen, G. S., LaFond-Walker, A., Herskowitz, A., and Rose, N. R., In vivo deposition of myosin-specific autoantibodies in the hearts of mice with experimental autoimmune myocarditis. J. Immunol. 148, 3806-3813, 1992.
34. Neumann, D. A., Rose, N. R., Ansari, A. A., and Herskowitz, A., Induction of multiple heart autoantibodies in mice with Coxsackievirus B3- and cardiac myosin-induced autoimmune myocarditis. J. Immunol. 152, 343-350, 1994.
35. Pummerer, C., Berger, P., Fruhwirth, M., Ofner, C., and Neu, N., Cellular infiltrate, major histocompatibility antigen expression and immunopathogenic mechanisms in cardiac myosin-induced myocarditis. Lab. Invest. 65, 538-547, 1991.
36. Neu, N., Ploier, B., and Ofner, C., Cardiac myosin-induced myocarditis: Heart autoantibodies are not involved in the induction of the disease. J. Immunol. 145, 4094-4100, 1990.
37. Smith, S. C., and Allen, P. M., Myosin-induced acute myocarditis is a T-cell mediated disease. J. Immunol. 147, 2141-2147, 1991.
38. Neu, N., Beisel, K. W., Traystman, M. D., Rose, N. R., and Craig, S. W., Autoantibodies specific for the cardiac myosin isoforms are found in mice susceptible to Coxsackievirus B3-induced myocarditis. J. Immunol. 138, 2488-2492, 1987.
39. Neu, N., Craig, S. W., Rose, N. R., Alvarez, F., and Beisel, K. W., Coxsackievirus-induced myocarditis in mice: Cardiac myosin autoantibodies do not cross-react with the virus. Clin. Exp. Immunol. 69, 566-574, 1987.
40. Lane, J. R., Neumann, D. A., Lafond-Walker, A., Herskowitz, A., and Rose, N. R., LPS promotes CB3-induced myocarditis in resistant B10.A mice. Cell. Immunol. 136, 219-223, 1991.
41. Lane, J. R., Neumann, D. A., Lafond-Walker, A., Herskowitz, A., and Rose, N. R., Interleukin-1 or tumor necrosis factor can promote Coxsackie B3-induced myocarditis in resistant B10.A mice. J. Exp. Med. 175, 1123-1129, 1992.
42. Bevilacqua, M. P., Stengelin, S., Gimbrone, M. A., and Seed, B., Endothelial leukocyte adhesion molecule 1: An inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science 243, 1160-1165, 1985.
43. Lane, J. R., Neumann, D. A., Lafond-Walker, A., Herskowitz, A., and Rose, N. R., Autoimmune myocarditis in resistant B10.A mice: Association with LPS-induced MHC expression. J. Cell Biochem. 15A, 256, 1991.
44. Billiau, A., Heremans, H., Vandekerckhove, F., Dijkmans, R., Sobi, S. H., Meulepas, E., and Carton, H., Enhancement of experimental allergic encephalomyocarditis in mice by antibodies against IFN-gamma. J. Immunol. 140, 1506-1510, 1988.
45. Finkel, M. S., Oddis, C. V., Jacob, T. D., Watkins, S. C., Hattler, B. J., and Simmons, R. L., Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science 257, 387-389, 1992.
46. Prabhakar, B. S., Srinivasappa, J., Beisel, K. W., and Notkins, A. L., Virus-induced autoimmunity: Cross-reactivity of antiviral antibodies with self-components. In "New Concepts in Viral Heart Disease" (H.-P. Schultheiss, Ed.), pp. 168-178, Springer-Verlag, Berlin, 1988.
47. Gaunt, C. J., Artepe, H. M., Higdon, A. L., Rozek, M. M., Cizawley, R., and Cunningham, M. W., Anti-Coxsackievirus B3 neutralizing antibodies with pathologic potential. Eur. Heart J. 12, 124-129, 1991.
48. Welleiz, A. H., Simpson, K., Hersum, M., van Houten, N., and Huber, S. A., Coxsackievirus B3-induced myocarditis: Virus receptor antibodies modulate myocarditis. J. Immunol. 143, 1843-1850, 1989.
49. Hohenadl, C., Klingel, K., Rieger, P., Hofschneider, P. H., and Kandolf, R., Investigation of the Coxsackievirus B3 nonstructural proteins 2B, 2C and 3AB: Generation of specific polyclonal antisera and detection of replicating virus in infected tissue. J. Virol. Methods 47, 279-295, 1994.
50. Chapman, N. M., Tu, Z., Tracy, S., and Gaunt, C. J., An infectious cDNA copy of the genome of a non-cardiovirulent Coxsackievirus B3 strain: Its complete sequence analysis and comparison to the genomes of cardiovirulent Coxsackieviruses. Arch. Virol. 135, 115-130, 1994.
51. Wegmann, K. W., Zhao, W., Griffin, A. C., and Hickey, W. F., Identification of myocarditogenic peptides derived from cardiac myosin capable of inducing experimental allezoic myocarditis in the Lewis rat. J. Immunol. 153, 892-900, 1994.