How novel methods can help discover more information about foodborne pathogens

Canadian Journal of Infectious Diseases

Volumn 11, Issue 3, 2000, Pages 142-153

  Griffiths, Mansel W ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

Bioluminescence; Ecology; Foodborne pathogens; Gene expression

Indexed keywords

ANALYTIC METHOD; ANTIBIOTIC SENSITIVITY; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BACTERIUM DETECTION; BIOFILM; BIOLUMINESCENCE; CONFERENCE PAPER; ECOLOGY; GENE EXPRESSION; PATHOGENESIS; REPORTER GENE; RISK ASSESSMENT;

EID: 0033938603     PISSN: 11802332     EISSN: None     Source Type: Journal    
DOI: 10.1155/2000/364050     Document Type: Conference Paper

References (150)

1. Campbell AK. Living light: biochemistry, function and biomedical applications. Essays Bioch 1989;24:41-81.
2. Meighen EA. Enzymes and genes from the lux operons of bioluminescent bacteria. Ann Rev Microbiol 1988;42:151-76.
3. Meighen EA. Molecular biology of bacterial bioluminescence. Microbiol Rev 1991;55:123-42.
4. Meighen EA. Molecular biology of bioluminescence. In: Stanley PE, Kricka LJ, eds. Bioluminescence and Chemiluminescence: Current Status. Chichester: John Wiley and Sons Ltd, 1991:3-10.
5. Meighen EA. Genetics of bacterial bioluminescence. Annu Rev Genet 1994;28:117-39.
6. Meighen EA, Dunlap PV. Physiological, biochemical and genetic control of bacterial bioluminescence. Adv Microb Physiol 1993;34:1-67.
7. Jacobs M, Hill PJ, Stewart GSAB. Highly bioluminescent Bacillus subtilis obtained through high-level expression of a luxAB fusion gene. Mol Gen Genet 1991;230:251-6.
8. Baker J, Griffiths MW, Collins-Thompson D. Bacterial bioluminesence: Application in food microbiology. J Food Prot 1992;55:62-70.
9. Chatterjee J, Meighen EA. Biotechnological applications of bacterial bioluminescence (lux) genes. Photochem Photobiol 1995;62:641-50.
10. Dodd CER, Stewart GSAB, Waites WM. Biotechnology-based methods for the detection, enumeration and epidemiology of food poisoning and spoilage organisms. Biotechnol Genet Eng Rev 1990;8:1-50.
11. Hill PJ, Stewart GSAB. Use of lux genes in applied biochemistry. J Biolumin Chemilumin 1994;9:211-5.
12. Hill PJ, Rees CED, Winson MK, Stewart GSAB. The application of lux genes. Biotechnol Appl Biochem 1993;17:3-14.
13. Jassim SAA, Ellison A, Denyer SP, Stewart GSAB. In vivo bioluminescence - a cellular reporter for research and industry. J Biolumin Chemilumin 1990;5:115-22.
14. Stewart GSAB. In vivo bioluminescence: new potentials for microbiology. Lett Appl Microbiol 1990;10:1-8.
15. Stewart GSAB. Challenging food microbiology from a molecular perspective. Microbiology 1997;143:2099-108.
16. Stewart GSAB, Williams P. lux genes and the applications of bacterial bioluminescence. J Gen Microbiol 1992;138:1289-300.
17. Stewart GSAB, Williams P. Shedding new light on food microbiology. The genes encoding bacterial bioluminescence are enabling microbiologists to better understand the complexities of bacterial adaptation and survival. ASM News 1993;59:241-6.
18. Stewart GSAB, Denyer SP, Lewington J. Microbiology illuminated: gene engineering and bioluminescence. Trends Food Sci Technol 1991;2:7-10.
19. Stewart G, Smith T, Denyer S. Genetic engineering for bioluminescent bacteria. Food Sci Technol Today 1989;3:19-22.
20. Schauer AT. Visualizing gene expression with luciferase fusions. Trends Biotechnol 1988;6:23-7.
21. Nordeen SK. Luciferase reporter gene vectors for analysis of promoters and enhancers. Biotechniques 1988;6:454-7.
22. O'Kane DJ, Lingle WL, Wampler JE, Legocki M, Legocki RP, Szalay AA. Visualization of bioluminescence as a marker of gene expression in rhizobium-infected soybean root nodules. Plant Mol Biol 1988;10:387-99.
23. Hooper CE, Ansorge RE, Browne HM, Tomkins P. CCD imaging of luciferase gene expression in single mammalian cells. J Biolumin Chemilumin 1990;5:123-30.
24. Masuko M, Hosoi S, Hayakawa T. A novel method for detection and counting of single bacteria in a wide field using an ultra-high-sensitivity TV camera without a microscope. FEMS Microbiol Lett 1991;81:287-90.
25. Blouin K, Walker SG, Smit J, Turner RFB. Characterization of in vivo reporter systems for gene expression and biosensor applications based on luxAB luciferase genes. Appl Environ Microbiol 1996;62:2013-21.
26. Chalfie M. Green fluorescent protein. Photochem Photobiol 1995;62:651-6.
27. Chalfie M, Tu Y, Euskirchen G, Ward WW, Prasher DC. Green fluorescent protein as a marker for gene expression. Science 1994;263:802-5.
28. Unge A, Tombolini R, Mølbak L, Jansson JK. Simultaneous monitoring of cell number and metabolic activity of specific bacterial populations with a dual gfp-luxAB marker system. Appl Environ Microbiol 1999;65:813-21.
29. Sheehan BJ, Foster TJ, Dorman CJ, Park S, Stewart GSAB. Osmotic and growth-phase dependent regulation of the eta gene of Staphylococcus aureus: a role for DNA supercoiling. Mol Gen Genet 1992;232:49-57.
30. Timmins BS, Holland KT. Shift-down in growth rate rather than high cell density induces toxic shock syndrome toxin-1 gene expression in Staphylococcus aureus. FEMS Microbiol Lett 1999;172:173-7.
31. Cossart P, Mengaud J. Listeria monocytogenes, a model system for the study of intracellular parasitism. Mol Biol Med 1989;6:463-74.
32. Mengaud J, Braun-Breton C, Cossart P. Identification of phosphatidylinositol specific phospholipase C activity in Listeria monocytogenes: a novel type of virulence factor. Mol Microbiol 1991;5:367-72.
33. Mengaud J, Dramsi S, Govin E, Vazquez-Boland JA, Milon G, Cossart P. Pleiotropic control of Listeria monocytogenes virulence factors by a gene that is autoregulated. Mol Microbiol 1991;5:2273-83.
34. Park SF, Stewart GSAB, Kroll RG. The use of bacterial luciferase of monitoring the environmental regulation of expression of genes encoding virulence factors in Listeria monocytogenes. J Gen Microbiol 1992;138:2619-27.
35. Renzoni A, Klarsfield A, Dramsi S, Cossart P. Evidence that PrfA, the pleiotropic activator of virulence genes in Listeria monocytogenes, can be present but inactive. Infect Immun 1997;65:1515-8.
36. Carmi OA, Stewart GSAB, Ulitzur S, Kuhn J. Use of bacterial luciferase to establish a promoter probe vehicle, capable of non-destructive real-time analysis of gene expression in Bacillus spp. J Bacteriol 1987;169:2165-70.
37. Cook N, Silcock DJ, Waterhouse RN, Prosser JI, Glover LA, Killham K. Construction and detection of bioluminescent strains of Bacillus subtilis. J Appl Bacteriol 1993;75:350-9.
38. Hall LR, Harding SE, Waites WM. Use of bioluminescence to study heat resistance of spores of Bacillus megaterium KM. J Appl Bacteriol 1990;69:xxiv.
39. Hill PJ, Hall L, Harding SE, et al. Bioluminescence and spores as biological indicators of inimical processes. Proceedings of the Society of Applied Bacteriology: 62nd Annual Meeting. July 13-16, 1993, Nottingham:v-vi.
40. Dodd CER, Sharman RL, Bloomfield SF, Booth IR, Stewart GSAB. Inimical processes-bacterial self-destruction and sub-lethal injury. Trends Food Sci Technol 1997;8:238-41.
41. Ellison A, Perry SF, Stewart GSAB. Bioluminescence as a real-time monitor of injury and recovery in Salmonella typhimurium. Int J Food Microbiol 1991;12:323-32.
42. Ferguson Y, Glover LA, McGillivray DM, Prosser JI. Survival and activity of lux-marked Aeromonas salmonicida in seawater. Appl Environ Microbiol 1995;61:3494-8.
43. Oliver JD, McDougald D, Barrett T, Glover LA, Prosser JI. Effect of temperature and plasmid carriage on nonculturability in organisms targeted for release. FEMS Microbiol Ecol 1995;17:229-38.
44. Duncan S, Glover LA, Killham K, Prosser JI. Luminescence-based detection of activity of starved and viable but nonculturable bacteria. Appl Environ Microbiol 1994;60:1308-16.
45. Bloomfield SF, Stewart GSAB, Dodd CER, Booth IR, Power EGM. The viable but non-culturable phenomenon explained? Microbiology 1998;144:1-3.
46. Park SF, Stirling DA, Hulton CS, Booth IR, Higgins CF, Stewart GSAB. A novel, non-invasive promoter probe vector: cloning of the osmoregulated proU promoter of Escherichia coli K12. Mol Microbiol 1989;3:1011-23.
47. Chen J, Griffiths MW. Luminescent Salmonella strains as real time reporters of growth and recovery from sublethal injury in food. Int J Food Microbiol 1996;31:27-43.
48. Bautista DA, Chen J, Barbut S, Griffiths MW. Use of an autobioluminescent Salmonella Hadar to monitor the effect of lactic acid on poultry carcasses. J Food Prot 1998;61:1439-45.
49. Rees CED, Dodd CER, Gibson PT, Booth IR, Stewart GSAB. The significance of bacteria in stationary phase to food microbiology. Int J Food Microbiol 1995;28:263-75.
50. Hengge Aronis R. Back to log phase-sigma-S as a global regulator in osmotic control of gene expression in Escherichia coli. Mol Microbiol 1996;21:887-93.
51. Kowarz L, Coynault C, Robbe-Saule V, Norel FTI. The Salmonella typhimurium katF (rpoS) gene-cloning, nucleotide-sequence and regulation of spvR and spvABCD virulence plasmid genes. J Bacteriol 1994;176:6852-60.
52. Swift S, Stewart GSAB. Luminescence as a signal of spvA expression. In: Campbell AK, Kricka LJ, Stanley PE, eds. Bioluminescence and Chemiluminescence: Fundamentals and Applied Aspects. Chichester: John Wiley and Sons, 1994:93-6.
53. Aldsworth TG, Sharman R, Dodd CER, Stewart GSAB. A competitive microflora increases the resistance of Salmonella typhimurium to inimical processes: Evidence for a suicide response. Appl Environ Microbiol 1998;64:1323-7.
54. Thompson JM, Stewart GSAB, Dodd CER. RpoS function in Salmonella Typhimurium LT2 monitored in a skim milk model food. J Food Prot 1999;62:70-2.
55. Belkin S, Smulski DR, Vollmer AC, Van Dyk TK, LaRossa RA. Oxidative stress detection with Escherichia coli harboring a katG′::lux fusion. Appl Environ Microbiol 1996;62:2252-6.
56. Ben-Israel O, Ben-Israel H, Ulitzur S. Identification and quantification of toxic chemicals by use of Escherichia coli carrying lux genes fused to stress promoters. Appl Environ Microbiol 1998;64:4346-52.
57. Dukan S, Dadon S, Smulski DR, Belkin S. Hypochlorous acid activates the heat shock and soxRS systems of Escherichia coli. Appl Environ Microbiol 1996;62:4003-8.
58. Van Dyk TK, Reed TR, Vollmer AC, LaRossa RA. Synergistic induction of the heat shock response in Escherichia coli by simultaneous treatment with chemical inducers. J Bacteriol 1995;177:6001-4.
59. Van Dyk TK, Smulski DR, Reed TR, Belkin S, Vollmer AC, LaRossa RA. Responses to toxicants of an Escherichia coli strain carrying a uspA::lux genetic fusion and an E. coli strain carrying a grpE::lux fusion are similar. Appl Environ Microbiol 1995;61:4124-7.
60. Vollmer AC, Belkin S, Smulski DR, Vandyk TK, Larossa RA. Detection of DNA damage by use of Escherichia coli carrying recA::lux, uvrA::lux, or alkA::lux reporter plasmids. Appl Environ Microbiol 1997;63:2566-71.
61. Chen J, Clarke RC, Griffiths MW. Use of luminescent strains of Salmonella enteritidis to monitor contamination and survival in eggs. J Food Prot 1996;59:915-21.
62. Fabricant JD, Chalmers JH Jr, Bradbury MW. Bioluminescent strains of E coli for the assay of biocides. Bull Environ Contaminat Toxicol 1995;54:90-5.
63. Stewart GSAB, Jassim SAA, Denyer SP. Mechanisms of action and rapid biocide testing. In: Denyer SP, Hugo WB, eds. Mechanisms of Action of Chemical Biocides: Their Study and Exploitation. Oxford: Blackwell Scientific Publications, 1991:319-29.
64. Simpson ML, Sayler GS, Applegate BM, et al. Bioluminescent-bioreporter integrated circuits form novel whole-cell biosensors. Trends Biotechnol 1998;16:332-8.
65. Wirtanen G, Nissinen V, Tikkanen L, Mattila Sandholm T. Use of Photobacterium leiognathi in studies of process equipment cleanability. Int J Food Sci Technol 1995;30:523-33.
66. Walker AJ, Jassim SAA, Holah JT, Denyer SP, Stewart GSAB. Bioluminescent Listeria monocytogenes provide a rapid assay for measuring biocide efficacy. FEMS Microbiol Lett 1992;91:251-5.
67. Walker AJ, Holah JT, Denyer SP, Stewart GSAB. The antibacterial activity of Virkon measured by colony growth and bioluminescence of lux recombinant Listeria monocytogenes. Lett Appl Microbiol 1992;15:80-2.
68. Park SF, Nissen U, Stewart GSAB. The cloning and expression of luxAB in Listeria monocytogenes. In: Stanley PE, Kricka LJ, eds. Bioluminescence and Chemiluminescence: Current Status. Chichester: John Wiley and Sons Ltd, 1991:35-8.
69. Dhir VK, Dodd CER. Susceptibility of suspended and surface-attached Salmonella enteritidis to biocides and elevated temperatures. Appl Environ Microbiol 1995;61:1731-8.
70. Lee S, Suzuki M, Tamiya E, Karube I. Microbial detection of toxic compounds utilizing recombinant DNA technology and bioluminescence. Anal Chim Acta 1991;244:201-6.
71. Virta M, Aekerman KEO, Saviranta P, Oker Blom C, Karp MT. Real-time measurement of cell permeabilization with low-molecular-weight membranolytic agents. J Antimicrob Chemother 1995;36:303-15.
72. Hibma AM, Jassim SAA, Griffiths MW. Infection and removal of L-forms of Listeria monocytogenes with bred bacteriophage. Int J Food Microbiol 1997;34:197-207.
73. Ulitzur S, Kuhn J. Introduction of lux genes into bacteria: a new approach for specific determination of bacteria and their antibiotic susceptibility. In: Schlomerich J, Andreesen R, Kapp A, et al, eds. Bioluminescence and Chemiluminescence New Perspectives. Chichester: John Wiley and Sons, 1987:463-72.
74. Hickey MJ, Arain TM, Shawar RM, et al. Luciferase in vivo expression technology: Use of recombinant mycobacterial reporter strains to evaluate antimycobacterial activity in mice. Antimicrob Agents Chemother 1996;40:400-7.
75. Contag CH, Contag PR, Mullins JI, Spilman SD, Stevenson DK, Benaron DA. Photonic detection of bacterial pathogens in living hosts. Mol Microbiol 1995;18:593-603.
76. Arain TM, Resconi AE, Singh DC, Stover CK. Reporter gene technology to assess activity of antimycobacterial agents in macrophages. Antimicrob Agents Chemother 1996;40:1542-4.
77. Angell P, Arrage AA, Mittelman MW, White DC. On line, non-destructive biomass determination of bacterial biofilms by fluorometry. J Microbiol Method 1993;18:317-27.
78. Denyer SP, Jassim SAA, Stewart GSAB. In vivo bioluminescence for studying the adhesion of bacteria. Biofouling 1991;5:125-32.
79. Mittelman MW, King JMH, Sayler GS, White DC. On-line detection of bacterial adhesion in a shear gradient with bioluminescence by a Pseudomonas fluorescens (lux) strain. J Microbiol Method 1992;15:53-60.
80. Nivens DE, Palmer RJ Jr, White DC. Continuous nondestructive monitoring of microbial biofilms: A review of analytical techniques. J Ind Microbiol 1995;15:263-76.
81. Mittelman MW, Packard J, Arrage AA, Bean SL, Angell P, White DC. Test systems for determining antifouling coating efficacy using on-line detection of bioluminescence and fluorescence in a laminar-flow environment. J Microbiol Method 1993;18:51-60.
82. Jassim SAA, Camprubi S, Tomas JM, et al. In vivo bioluminescence for studying bacterial adhesion and in vitro phagocytosis. In: Szalay A, Kricka L, Stanley P, eds. Bioluminescence and Chemiluminescence: Status Report. Chichester: John Wiley and Sons Ltd, 1993:491-5.
83. Rice JF, Fowler RF, Arrage AA, White DC, Sayler GS. Effects of external stimuli on environmental bacterial strains harboring an algD-lux bioluminescent reporter plasmid for the study of corrosive biofilms. J Ind Microbiol 1995;15:318-28.
84. Chumkhunthod P, Schraft H, Griffiths MW. Rapid monitoring method to assess the efficacy of sanitizers against Pseudomonas putida biofilms. J Food Prot 1998;61:1043-6.
85. Hibma AM, Jassim SAA, Griffiths MW. In vivo bioluminescence to detect the attachment of L-forms of Listeria monocytogenes to food and clinical contact surfaces. Int J Food Microbiol 1996;33:157-67.
86. Siragusa GR, Nawotka K, Spilman SD, Contag PR, Contag CH. Real-time monitoring of Escherichia coli O157:H7 adherence to beef carcass surface tissues with a bioluminescent reporter. Appl Environ Microbiol 1999;65:1738-45.
87. Prosser JI, Killham K, Glover LA, Rattray EAS. Luminescence-based systems for detection of bacteria in the environment. Crit Rev Biotechnol 1996;16:157-83.
88. Hudson LM, Chen J, Hill AR, Griffiths MW. Bioluminescence - a rapid indicator of Escherichia coli O157:H7 in selected yogurt and cheese varieties. J Food Prot 1997;60:891-7.
89. Ramsaran H, Chen J, Brunke B, Hill A, Griffiths MW. Survival of bioluminescent Listeria monocytogenes and E coli O157:H7 in soft cheeses. J Dairy Sci 1998;81:1810-7.
90. Tomicka A, Chen J, Barbut S, Griffiths MW. Survival of bioluminescent E coli O157:H7 in a model system representing fermented sausage production. J Food Prot 1997;60:1487-92.
91. Fratamico PM, Deng MY, Strobaugh TP, Palumbo SA. Construction and characterization of Escherichia coli O157:H7 strains expressing firefly luciferase and green fluorescent protein and their use in survival studies. J Food Prot 1997;60:1167-73.
92. Duffy G, Ellison A, Anderson W, Cole MB, Stewart GSAB. Use of bioluminescence to model the thermal inactivation of Salmonella typhimurium in the presence of a competitive microflora. Appl Environ Microbiol 1995;61:3463-5.
93. Ellison A, Anderson W, Cole MB, Stewart GSAB. Modelling the thermal inactivation of Salmonella typhimurium using bioluminescence data. Int J Food Microbiol 1994;23:467-77.
94. Mettenleiter TC, Graewe W. Video imaging of firefly luciferase activity to identify and monitor herpesvirus infection in cell culture. J Virol Methods 1996;59:155-60.
95. Hammermueller JD, Gyles CL. The development of a rapid bioluminescent Vero cell assay. In: Karmali MA, Goglio AG, eds. Recent advances in verocytotoxin-producing Escherichia coli infections. Amsterdam: Elsevier, 1994:113-6.
96. Contag PR, Olomu IN, Stevenson DK, Contag CH. Bioluminescent indicators in living mammals. Nat Med 1998;4:245-7.
97. Contag CH, Spilman SD, Contag PR, et al. Visualizing gene expression in living mammals using a bioluminescent reporter. Photochem Photobiol 1997;66:523-31.
98. Swift S, Throup JP, Williams P, Salmond GPC, Stewart GSAB. Quorum sensing: a population density component in the determination of bacterial phenotype. Trends Biochem Sci 1996;21:214-9.
99. Winson MK, Camara M, Latifi A, et al. Multiple N-acyl-L-homoserine lactone signal molecules regulate production of virulence determinants and secondary metabolites in Pseudomonas aeruginosa. Proc Natl Acad Sci (USA) 1995;92:9427-31.
100. Parsek MR, Val DL, Hanzelka BL, Cronan JE Jr, Greenberg EP. Acyl homoserine-lactone quorum sensing signal generation. Proc Natl Acad Sci (USA) 1999;96:4360-5.
101. Guard-Petter J. Variants to smooth Salmonella enterica serovar Enteritidis that grow to higher cell density than the wild type are more virulent. Appl Environ Microbiol 1998;64:2166-72.
102. + bacteriophages. J Food Prot 1996;59:908-14.
103. Mead PS, Slutsker L, Dietz V, et al. Food-related illness and death in the United States. Emerg Infect Dis 1999;5:607-25.
104. Ronner AB, Cliver DO. Isolation and characterization of a coliphage specific for Escherichia coli O157:H7. J Food Prot 1990;53:944-7.
105. Pagotto F, Brovko L, Griffiths MW. Phage-mediated detection of Staphylococcus aureus and E coli O157:H7 using bioluminescence. Symposium on Bacteriological Quality of Raw Milk. Brussels: International Dairy Federation, 1996:152-6.
106. Turpin PE, Maycroft KA, Bedford J, Rowlands CL, Wellington EMH. A rapid luminescent-phage based MPN method for the enumeration of Salmonella typhimurium in environmental samples. Lett Appl Microbiol 1993;16:24-7.
107. Loessner MJ, Rees CED, Stewart GSAB, Scherer S. Construction of luciferase reporter bacteriophage A511::luxAB for rapid and sensitive detection of viable Listeria cells. Appl Environ Microbiol 1996;62:1133-40.
108. Loessner MJ, Rudolf M, Scherer S. Evaluation of luciferase reporter bacteriophage A511::luxAB for detection of Listeria monocytogenes in contaminated foods. Appl Environ Microbiol 1997;63:2961-5.
109. Jacobs WR Jr, Barletta RG, Udani R, et al. Rapid assessment of drug susceptibilities of Mycobacterium tuberculosis by means of luciferase reporter phages. Science 1993;260:819-22.
110. Sarkis GJ, Jacobs WR, Hatfull GF. L5 luciferase reporter mycobacteriophages - a sensitive tool for the detection and assay of live mycobacteria. Mol Microbiol 1995;15:1055-67.
111. Cebolla A, Vazquez ME, Palomares AJ. Expression vectors for the use of eukaryotic luciferases as bacterial markers with different colors of luminescence. Appl Environ Microbiol 1995;61:660-8.
112. Hastings JW. Chemistries and colors of bioluminescent reactions: A review. Gene 1996;173:5-11.
113. Kodicara CP, Crew HH, Stewart GSAB. Near on-line detection of enteric bacteria using lux recombinant bacteriophage. FEMS Microbiol Lett 1991;83:261-6.
114. Delong EF, Steinhauer D, Israel A, Nealson KH. Isolation of the lux genes from Photobacterium leiognathi and expression in Escherichia coli. Gene 1987;54:203-10.
115. Mancini JA, Boylan M, Soly RR, Graham AF, Meighen EA. Cloning and expression of the Photobacterium phosphoreum luminescence system demonstrates a unique lux gene organization. J Biol Chem 1988;263:14308-14.
116. Engebrecht J, Nealson KH, Silverman M. Bacterial bioluminescence: isolation and genetic analysis of functions from Vibrio fischeri. Cell 1983;32:773-81.
117. Baldwin TO, Berends T, Bunch TA, et al. Cloning of the luciferase structural genes from Vibrio harveyi and the expression of bioluminescence in Escherichia coli. Biochemistry 1984;23:3663-7.
118. Belas R, Mileham A, Cohn D, Hilmen M, Simon M, Silverman M. Bacterial bioluminescence: isolation and expression of the luciferase genes from Vibrio harveyi. Science 1982;218:791-3.
119. Cohn DH, Ogden RC, Abelson JN, et al. Cloning of Vibrio harveyi luciferase genes: use of a synthetic oligonucleotide probe. Proc Natl Acad Sci (USA) 1983;80:120-3.
120. Frackman S, Anhalt M, Nealson KH. Cloning, organization and expression of the bioluminescence genes of Xenorhabdus luminescens. J Bacteriol 1990;172:5767-73.
121. Szittner R, Meighen EI. Nucleotide sequence, expression and properties of luciferase coded by lux genes from a terrestrial bacterium. J Biol Chem 1990;265:16581-7.
122. Masuda T, Tatsumi M, Nakano E. Cloning and sequence analysis of cDNA for luciferase of a Japanese firefly, Luciola cruciata. Gene 1989;77:265-70.
123. Tatsumi H, Kajiyama N, Nakano E. Molecular cloning and expression in Escherichia coli of a cDNA clone encoding luciferase of a firefly, Luciola lateralis. Biochim Biophys Acta 1992;1131:161-5.
124. Devine JH, Kutuzova GD, Green VA, Ugarova NN, Baldwin TO. Luciferase from the East European firefly L mingrelica: cloning and nucleotide sequence of the cDNA, overexpression in Escherichia coli and purification of the enzyme. Biochim Biophys Acta 1993;1173:121-32.
125. De Wet JR, Wood KV, Helinski DR, DeLuca M. Cloning of firefly luciferase cDNA and the expression of active luciferase in Escherichia coli. Proc Natl Acad Sci (USA) 1985;82:7870-3.
126. Wood KV, Lam YA, Seliger HH, McElroy WD. Complementary DNA coding click beetle luciferases can elicit bioluminescence of different colors. Science 1989;244:700-2.
127. Prasher DC, McCann CO, Longiaru M, Cormier MJ. Sequence comparisons of complementary DNAs encoding aequorin isotypes. Biochemistry 1987;26:1326-32.
128. Thompson EM, Nagata S, Tsuji FI. Cloning and expression of cDNA from the marine ostracod Vargula hilgendorfii. Proc Natl Acad Sci (USA) 1989;86:6567-71.
129. Lorenz WW, McCann RO, Longiaru M, Cormier MJ. Isolation and expression of a cDNA encoding Renilla reniformis luciferase. Proc Natl Acad Sci (USA) 1991;88:4438-42.
130. 2+-activated photoprotein, clytin. FEBS Letters 1993;315:343-6.
131. Illarionov BA, Marcova SV, Bondar VA, Vysotsky ES, Gitelson JI. [Cloning and expression of cDNA and Ca2+-activated photoprotein obelin from the hydroid polyp Obelia longissima]. Dokl Akad Nauk SSSR 1992;326:911-4.
132. Matz MV, Fradkov AF, Labas YA, et al. Fluorescent proteins from nonbioluminescent Anthozoa species. Nat Biotechnol 1999;17:969-73.
133. Ferguson Y, McGillivray DM, Prosser JI, Glover LA. Luminescence-based detection of the fish pathogen Aeromonas salmonicida. 3rd International Marine Biotechnology Conference 1994; Tromsoe, Norway, 1994:128. [Abst]
134. Boivin R, Chalifour F-P, Dion P. Construction of a Tn5 derivative encoding bioluminescence and its introduction in Pseudomonas, Agrobacterium and Rhizobium. Mol Gen Genet 1988;213:50-5.
135. Shaw JJ, Kado CI. Development of a Vibrio gene-set to monitor phytopathogenic bacteria during the on-going disease process in a non-disruptive manner. BioTechnology 1986;4:60-4.
136. Legocki RP, Legocki M, Baldwin TO, Szalay AA. Bioluminescence in soybean root nodules: demonstration of a general approach to assay gene expression in vivo by using bacterial luciferase. Proc Natl Acad Sci (USA) 1986;83:9080-4.
137. m's for aldehyde in recombinant bacteria expressing luxA/B. Lett Appl Microbiol 1989;9:149-52.
138. Flemming CA, Lee H, Trevors JT. Bioluminescent most-probable-number method to enumerate lux-marked Pseudomonas aeruginosa UG2Lr in soil. Appl Environ Microbiol 1994;60:3458-61.
139. Engebrecht J, Simon M, Silverman M. Measuring gene expression with light. Science 1985;227:1345-7.
140. Kaniga K, Sory M-P, Delor I, Saegerman C, Limet JN, Cornelis GR. Monitoring of Yersinia enterocolitica in murine and bovine feces on the basis of the chromosomally integrated luxAB marker gene. Appl Environ Microbiol 1992;58:1024-6.
141. Karp M, Meyer P. Expression of bacterial luciferase genes from Vibrio harveyi in Bacillus subtilis and Escherichia coli. Biochim Biophys Acta 1989;1007:84-90.
142. Lampinen J, Koivisto L, Wahlsten M, Mäntsälä P, Karp M. Expression of luciferase genes from different origins in Bacillus subtilis. Mol Gen Genet 1992;232:498-505.
143. Wang G, Mayerhofer R, Langridge WHR, et al. Expression of a bacterial luciferase marker gene in Bacillus species. In: Szalay A, Kricka L, Stanley P, eds. Bioluminescence and Chemiluminescence: Status Report. Chichester: John Wiley and Sons Ltd, 1993:232-6.
144. Purdy D, Park SF. Heterologous gene expression Campylobacter coli: The use of bacterial luciferase in a promoter probe vector. FEMS Microbiol Lett 1993;111:233-7.
145. Phillips-Jones MK. Bioluminescence (lux) expression in the anaerobe Clostridium perfringens. FEMS Microbiol Lett 1993;106:265-70.
146. Ahmad KA, Stewart GSAB. The production of bioluminescent lactic acid bacteria suitable for the rapid assessment of starter culture activity in milk. J Appl Bacteriol 1991;70:113-20.
147. Eaton TJ, Shearman CA, Gasson MJ. The use of bacterial luciferase genes as reporter genes in Lactococcus: Regulation of the Lactococcus lactis subsp. lactis lactose genes. J Gen Microbiol 1993;139:1495-501.
148. Park SF, Stewart GSAB. High efficiency transformation of Listeria monocytogenes by electroporation of penicillin-treated cells. Gene 1990;94:129-32.
149. Jacobs MF, Tynkkynen S, Sibakov M. Highly bioluminescent Streptococcus thermophilus strain for the detection of dairy-relevant antibiotics in milk. Appl Microbiol Biotechnol 1995;44:405-12.
150. Kirchner G, Roberts JL, Gustafson GD, Ingolia TD. Active bacterial luciferase from a fused gene: expression of a Vibrio harveyi luxAB translational fusion in bacteria, yeast and plant cells. Gene 1989;81:349-54.