The enantioselectivity of enzymes involved in current antiviral therapy using nucleoside analogues: A new strategy?

Antiviral Chemistry and Chemotherapy

Volumn 11, Issue 3, 2000, Pages 165-189

  Maury, Georges ^a  

^a UNIVERSITÉ DE MONTPELLIER   (France)

Author keywords

Enantioselectivity; L nucleosides; Nucleoside metabolizing enzymes; Viral enzymes; Virus inhibitors

Indexed keywords

ABACAVIR; ADENOSINE DEAMINASE; ANTIVIRUS AGENT; CYTIDINE DEAMINASE; DEOXYCYTIDINE KINASE; DEOXYGUANOSINE DERIVATIVE; DEOXYGUANOSINE KINASE; DEOXYURIDINE DERIVATIVE; DIDANOSINE; DNA POLYMERASE; EDOXUDINE; IDOXURIDINE; LAMIVUDINE; NUCLEOSIDE; NUCLEOSIDE ANALOG; NUCLEOTIDE; PENCICLOVIR; PHOSPHOTRANSFERASE; RNA DIRECTED DNA POLYMERASE; STAVUDINE; THYMIDINE KINASE; TRIFLURIDINE; VIDARABINE; VIRUS DNA; VIRUS ENZYME; ZALCITABINE; ZIDOVUDINE;

ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; BINDING KINETICS; CATABOLISM; DRUG DESIGN; DRUG MECHANISM; DRUG SELECTIVITY; ENANTIOMER; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME PURIFICATION; ENZYME SPECIFICITY; HEPATITIS B VIRUS; HERPES SIMPLEX VIRUS; HUMAN IMMUNODEFICIENCY VIRUS; NONHUMAN; PRIORITY JOURNAL; REVIEW; STRUCTURE ACTIVITY RELATION; VIRUS INHIBITION; VIRUS REPLICATION;

EID: 0033934998     PISSN: 09563202     EISSN: None     Source Type: Journal    
DOI: 10.1177/095632020001100301     Document Type: Review

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