Enzymatic properties of the unnatural β-L-enantiomers of 2',3'- dideoxyadenosine and 2',3'-didehydro-2',3'-dideoxyadenosine

Journal of Medicinal Chemistry

Volumn 40, Issue 24, 1997, Pages 3969-3973

  Pélicano, Hélène ^a   Pierra, Claire ^a   Eriksson, Staffan ^b   Gosselin, Gilles ^a   Imbach, Jean Louis ^a   Maury, Georges ^a  

^a European Theoretical Spectroscopy Facility   (France)

^b SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

2',3' DIDEHYDRO 2',3' DIDEOXYNUCLEOSIDE; 2',3' DIDEOXYADENOSINE; ADENOSINE DEAMINASE; ADENOSINE DERIVATIVE; ADENOSINE KINASE; ANTIVIRUS AGENT; DEOXYCYTIDINE KINASE; PURINE NUCLEOSIDE PHOSPHORYLASE;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENANTIOMER; ENZYME INHIBITION; ENZYME SPECIFICITY; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ADENOSINE DEAMINASE; ADENOSINE KINASE; ANIMALS; ANTI-HIV AGENTS; ANTIVIRAL AGENTS; CATTLE; DEOXYCYTIDINE KINASE; DIDEOXYADENOSINE; DRUG STABILITY; HEPATITIS B VIRUS; HIV; HUMANS; PURINE-NUCLEOSIDE PHOSPHORYLASE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030781982     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9701482     Document Type: Article

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