-
1
-
-
0028998836
-
5A, showing the pathway of phosphoryl transfer
-
5A, showing the pathway of phosphoryl transfer. Protein Sci 4:1262-1271.
-
(1995)
Protein Sci
, vol.4
, pp. 1262-1271
-
-
Abele, U.1
Schulz, G.E.2
-
2
-
-
0025640814
-
Herpesviral deoxythymidine kinases contain a site analogous to the phosphoryl-binding arginine-rich region of porcine adenylate kinase; comparison of secondary structure predictions and conservations
-
Balasubramaniam NK, Veerisetty V, Gentry GA. 1990. Herpesviral deoxythymidine kinases contain a site analogous to the phosphoryl-binding arginine-rich region of porcine adenylate kinase; comparison of secondary structure predictions and conservations. J Gen Virol 71:2979-2987.
-
(1990)
J Gen Virol
, vol.71
, pp. 2979-2987
-
-
Balasubramaniam, N.K.1
Veerisetty, V.2
Gentry, G.A.3
-
3
-
-
0027501570
-
Identification of important residues within the putative nucleoside binding site of HSV-1 thymidine kinase by random sequence selection: Analysis of selected mutants in vitro
-
Black ME, Loeb LA. 1993. Identification of important residues within the putative nucleoside binding site of HSV-1 thymidine kinase by random sequence selection: Analysis of selected mutants in vitro. Biochemistry 32:11618-11626.
-
(1993)
Biochemistry
, vol.32
, pp. 11618-11626
-
-
Black, M.E.1
Loeb, L.A.2
-
4
-
-
0029125949
-
Crystal structures of the thymidine kinase from Herpes simplex virus type-1 in complex with deoxythymidine and ganciclovir
-
Brown DG, Visse R, Sandhu G, Davies A, Rizkallah PJ, Melitz C, Summers WC, Sanderson MR. 1995. Crystal structures of the thymidine kinase from Herpes simplex virus type-1 in complex with deoxythymidine and ganciclovir. Nature Struct Biol 2:876-881.
-
(1995)
Nature Struct Biol
, vol.2
, pp. 876-881
-
-
Brown, D.G.1
Visse, R.2
Sandhu, G.3
Davies, A.4
Rizkallah, P.J.5
Melitz, C.6
Summers, W.C.7
Sanderson, M.R.8
-
5
-
-
0023140814
-
Crystallographic R-factor refinement by molecular dynamics
-
Brünger AT, Kuriyan J, Karplus M. 1987. Crystallographic R-factor refinement by molecular dynamics. Science 235:458-460.
-
(1987)
Science
, vol.235
, pp. 458-460
-
-
Brünger, A.T.1
Kuriyan, J.2
Karplus, M.3
-
6
-
-
0018413243
-
Characterization of pyrimidine deoxyribonucleoside kinase (thymidine kinase) and thymidylate kinase as a multifunctional enzyme in cells transformed by Herpes simplex virus type 1 and in cells infected with mutant strains of Herpes simplex virus
-
Chen MS, Summers WP, Walker J, Summers WC, Prusoff WH. 1979a. Characterization of pyrimidine deoxyribonucleoside kinase (thymidine kinase) and thymidylate kinase as a multifunctional enzyme in cells transformed by Herpes simplex virus type 1 and in cells infected with mutant strains of Herpes simplex virus. J Virol 30:942-945.
-
(1979)
J Virol
, vol.30
, pp. 942-945
-
-
Chen, M.S.1
Summers, W.P.2
Walker, J.3
Summers, W.C.4
Prusoff, W.H.5
-
7
-
-
0018603658
-
Kinetic studies of Herpes simplex virus type-1 encoded thymidine and thymidylate kinase, a multifunctional protein
-
Chen MS, Walker J, Prusoff WH. 1979b. Kinetic studies of Herpes simplex virus type-1 encoded thymidine and thymidylate kinase, a multifunctional protein. J Biol Chem 254:10747-10753.
-
(1979)
J Biol Chem
, vol.254
, pp. 10747-10753
-
-
Chen, M.S.1
Walker, J.2
Prusoff, W.H.3
-
8
-
-
0027159949
-
The molecular surface package
-
Connolly ML. 1993. The molecular surface package. J Mol Graphics 17:139-141.
-
(1993)
J Mol Graphics
, vol.17
, pp. 139-141
-
-
Connolly, M.L.1
-
9
-
-
0026772206
-
In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors
-
Culver KW, Ram Z, Wallbridge S, Ishii H, Oldfield EH, Blaese RM. 1992. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science 256:1550-1552.
-
(1992)
Science
, vol.256
, pp. 1550-1552
-
-
Culver, K.W.1
Ram, Z.2
Wallbridge, S.3
Ishii, H.4
Oldfield, E.H.5
Blaese, R.M.6
-
10
-
-
0022550413
-
Evidence that the "active center" of Herpes simplex virus thymidine kinase involves an interaction between three distinct regions of the polypeptide
-
Darby G, Larder BA, Inglis MM. 1986. Evidence that the "active center" of Herpes simplex virus thymidine kinase involves an interaction between three distinct regions of the polypeptide. J Gen Virol 67:753-758.
-
(1986)
J Gen Virol
, vol.67
, pp. 753-758
-
-
Darby, G.1
Larder, B.A.2
Inglis, M.M.3
-
11
-
-
0027283742
-
Antivirals for the treatment of Herpesvirus infections
-
De Clercq E. 1993. Antivirals for the treatment of Herpesvirus infections. J Antimicrobial Chemotherapy Suppl A 32:121-132.
-
(1993)
J Antimicrobial Chemotherapy Suppl A
, vol.32
, pp. 121-132
-
-
De Clercq, E.1
-
12
-
-
0023024626
-
The glycine loop of adenylate kinase forms a giant anion hole
-
Dreusicke D, Schulz GE. 1986. The glycine loop of adenylate kinase forms a giant anion hole. FEBS Lett 208:301-304.
-
(1986)
FEBS Lett
, vol.208
, pp. 301-304
-
-
Dreusicke, D.1
Schulz, G.E.2
-
13
-
-
0027256555
-
Site-directed mutagenesis in the active site of the Herpes simplex virus type 1 thymidine kinase
-
Fetzer J, Folkers G, Müller I, Keil GM. 1993. Site-directed mutagenesis in the active site of the Herpes simplex virus type 1 thymidine kinase. Virus Genes 7:205-209.
-
(1993)
Virus Genes
, vol.7
, pp. 205-209
-
-
Fetzer, J.1
Folkers, G.2
Müller, I.3
Keil, G.M.4
-
14
-
-
0028518902
-
A fast method for obtaining highly pure recombinant Herpes simplex virus type 1 thymidine kinase
-
Fetzer J, Michael M, Bohner T, Hofbauer R, Folkers G. 1994. A fast method for obtaining highly pure recombinant Herpes simplex virus type 1 thymidine kinase. Prot Exp Purif 5:432-441.
-
(1994)
Prot Exp Purif
, vol.5
, pp. 432-441
-
-
Fetzer, J.1
Michael, M.2
Bohner, T.3
Hofbauer, R.4
Folkers, G.5
-
15
-
-
0026233932
-
Computer-aided active site-directed modeling of the Herpes simplex virus type 1 and human thymidine kinase
-
Folkers G, Trumpp-Kallmeyer S, Gutbrod O, Krickl S, Fetzer J, Keil GM. 1991. Computer-aided active site-directed modeling of the Herpes simplex virus type 1 and human thymidine kinase. J Comp Aid Mol Design 5:385-404.
-
(1991)
J Comp Aid Mol Design
, vol.5
, pp. 385-404
-
-
Folkers, G.1
Trumpp-Kallmeyer, S.2
Gutbrod, O.3
Krickl, S.4
Fetzer, J.5
Keil, G.M.6
-
16
-
-
1842285152
-
Locating a nucleotide-binding site in the thymidine kinase of vaccinia virus and of Herpes simplex virus by scoring triply-aligned protein sequences
-
Gentry GA. 1985. Locating a nucleotide-binding site in the thymidine kinase of vaccinia virus and of Herpes simplex virus by scoring triply-aligned protein sequences. Proc Natl Acad Sci USA 55:6815-6819.
-
(1985)
Proc Natl Acad Sci USA
, vol.55
, pp. 6815-6819
-
-
Gentry, G.A.1
-
17
-
-
0021261522
-
Effects of deletions on expression of the Herpes simplex virus thymidine kinase gene from the intact viral genome: The amino terminus of the enzyme is dispensable for catalytic activity
-
Halpern ME, Smiley JR. 1984. Effects of deletions on expression of the Herpes simplex virus thymidine kinase gene from the intact viral genome: The amino terminus of the enzyme is dispensable for catalytic activity. J Virol 50:733-738.
-
(1984)
J Virol
, vol.50
, pp. 733-738
-
-
Halpern, M.E.1
Smiley, J.R.2
-
18
-
-
0026094411
-
Evolution of herpesvirus thymidine kinases from cellular deoxycytidine kinase
-
Harrison PT, Thompson R, Davison AJ. 1991. Evolution of herpesvirus thymidine kinases from cellular deoxycytidine kinase. J Gen Virol 72:2583-2586.
-
(1991)
J Gen Virol
, vol.72
, pp. 2583-2586
-
-
Harrison, P.T.1
Thompson, R.2
Davison, A.J.3
-
19
-
-
0028928572
-
Acyclic guanosine analogs inhibit DNA polymerases α, δ, and ε with very different potencies and have unique mechanisms of action
-
Ilsley DD, Lee SH, Miller WH, Kuchta RD. 1995. Acyclic guanosine analogs inhibit DNA polymerases α, δ, and ε with very different potencies and have unique mechanisms of action. Biochemistry 34:2504-2510.
-
(1995)
Biochemistry
, vol.34
, pp. 2504-2510
-
-
Ilsley, D.D.1
Lee, S.H.2
Miller, W.H.3
Kuchta, R.D.4
-
20
-
-
0029109468
-
Protein-protein interactions: A review of protein dimer structures
-
Jones S, Thomton JM. 1995. Protein-protein interactions: A review of protein dimer structures. Prog Biophys Molec Biol 63:31-65.
-
(1995)
Prog Biophys Molec Biol
, vol.63
, pp. 31-65
-
-
Jones, S.1
Thomton, J.M.2
-
21
-
-
85046526624
-
Evaluation of single-crystal X-ray diffraction data from a position-sensitive detector
-
Kabsch W. 1988. Evaluation of single-crystal X-ray diffraction data from a position-sensitive detector. J Appl Cryst 27:916-924.
-
(1988)
J Appl Cryst
, vol.27
, pp. 916-924
-
-
Kabsch, W.1
-
22
-
-
0020997912
-
Dictionary of protein secondary structures: Pattern recognition of hydrogen-bonded and geometrical features
-
Kabsch W, Sander C. 1983. Dictionary of protein secondary structures: Pattern recognition of hydrogen-bonded and geometrical features. Biopolymers 22:2577-2637.
-
(1983)
Biopolymers
, vol.22
, pp. 2577-2637
-
-
Kabsch, W.1
Sander, C.2
-
23
-
-
0022377428
-
Thymidine kinase
-
Kit S. 1985. Thymidine kinase. Microbiol Sciences 2:369-375.
-
(1985)
Microbiol Sciences
, vol.2
, pp. 369-375
-
-
Kit, S.1
-
24
-
-
0020633163
-
Characterization of abnormal thymidine kinases induced by drug-resistant strains of Herpes simplex virus type 1
-
Larder BA, Cheng Y-C, Darby G. 1983. Characterization of abnormal thymidine kinases induced by drug-resistant strains of Herpes simplex virus type 1. J Gen Virol 64:523-532.
-
(1983)
J Gen Virol
, vol.64
, pp. 523-532
-
-
Larder, B.A.1
Cheng, Y.-C.2
Darby, G.3
-
25
-
-
0000243829
-
PROCHECK: A program to check the stereochemical quality of protein structures
-
Laskowski RA, MacArthur MW, Moss DS, Thornton JM. 1993. PROCHECK: A program to check the stereochemical quality of protein structures. J Appl Cryst 26:283-291.
-
(1993)
J Appl Cryst
, vol.26
, pp. 283-291
-
-
Laskowski, R.A.1
MacArthur, M.W.2
Moss, D.S.3
Thornton, J.M.4
-
26
-
-
0028169328
-
Kinetic studies with N2-phenylguanines and with L-thymidine indicate that Herpes simplex virus type 1 thymidine kinase and thymidylate kinase share a common active site
-
Maga G, Focher F, Wright GE, Capobianco M, Garbesi A, Bendiscioli A, Spadari S. 1994. Kinetic studies with N2-phenylguanines and with L-thymidine indicate that Herpes simplex virus type 1 thymidine kinase and thymidylate kinase share a common active site. Biochem J 302:279-282.
-
(1994)
Biochem J
, vol.302
, pp. 279-282
-
-
Maga, G.1
Focher, F.2
Wright, G.E.3
Capobianco, M.4
Garbesi, A.5
Bendiscioli, A.6
Spadari, S.7
-
27
-
-
0019295352
-
The nucleotide sequence and transcript map of the Herpes simplex virus thymidine kinase gene
-
McKnight SL. 1980. The nucleotide sequence and transcript map of the Herpes simplex virus thymidine kinase gene. Nucleic Acids Res 5:5949-5964.
-
(1980)
Nucleic Acids Res
, vol.5
, pp. 5949-5964
-
-
McKnight, S.L.1
-
29
-
-
0024581156
-
Analysis of the bovine Herpesvirus type 1 thymidine kinase (TK) gene from wild-type virus and TK-deficient mutants
-
Mittal SK, Field HJ. 1989. Analysis of the bovine Herpesvirus type 1 thymidine kinase (TK) gene from wild-type virus and TK-deficient mutants. J Gen Virol 70:901-918.
-
(1989)
J Gen Virol
, vol.70
, pp. 901-918
-
-
Mittal, S.K.1
Field, H.J.2
-
30
-
-
0025323406
-
Evidence for in vivo synthesis of thiamine triphosphate by cytosolic adenylate kinase in chicken skeletal muscle
-
Miyoshi K, Egi Y, Shioda T, Kawasaki T. 1990. Evidence for in vivo synthesis of thiamine triphosphate by cytosolic adenylate kinase in chicken skeletal muscle. J Biochem 108:261-210.
-
(1990)
J Biochem
, vol.108
, pp. 261-1210
-
-
Miyoshi, K.1
Egi, Y.2
Shioda, T.3
Kawasaki, T.4
-
31
-
-
0026544877
-
5a refined at 1.9 Å resolution: A model for a catalytic transition state
-
5A refined at 1.9 Å resolution: A model for a catalytic transition state. J Mol Biol 224:159-177.
-
(1992)
J Mol Biol
, vol.224
, pp. 159-177
-
-
Müller, C.W.1
Schulz, G.E.2
-
32
-
-
0028942595
-
Substrate specificity and assembly of the catalytic center derived from two structures of ligated uridylate kinase
-
Müller-Dieckmann H-J, Schulz GE. 1995. Substrate specificity and assembly of the catalytic center derived from two structures of ligated uridylate kinase. J Mol Biol 246:522-530.
-
(1995)
J Mol Biol
, vol.246
, pp. 522-530
-
-
Müller-Dieckmann, H.-J.1
Schulz, G.E.2
-
33
-
-
0027185675
-
Reversible ATP-dependent transition between two forms of human cytosolic thymidine kinase with different enzymatic properties
-
Munch-Petersen B, Tyrsted G, Cloos L. 1993. Reversible ATP-dependent transition between two forms of human cytosolic thymidine kinase with different enzymatic properties. J Biol Chem 268:15621-15625.
-
(1993)
J Biol Chem
, vol.268
, pp. 15621-15625
-
-
Munch-Petersen, B.1
Tyrsted, G.2
Cloos, L.3
-
34
-
-
0026646614
-
Permissible amino acid substitutions within the putative nucleoside-binding site of Herpes simplex virus type 1 encoded thymidine kinase established by random sequence mutagenesis
-
Munir KM, French DC, Dube DK, Loeb LA. 1992. Permissible amino acid substitutions within the putative nucleoside-binding site of Herpes simplex virus type 1 encoded thymidine kinase established by random sequence mutagenesis. J Biol Chem 267:6584-6589.
-
(1992)
J Biol Chem
, vol.267
, pp. 6584-6589
-
-
Munir, K.M.1
French, D.C.2
Dube, D.K.3
Loeb, L.A.4
-
35
-
-
0002452464
-
Oscillation data reduction program
-
Sawyer L, Isaacs N, Bailey S, eds. Warrington, United Kingdom: SERC Daresbury Laboratory
-
Otwinowski Z. 1993. Oscillation data reduction program. In: Sawyer L, Isaacs N, Bailey S, eds. Data collection and processing. Proceedings of the CCP4 study weekend. Warrington, United Kingdom: SERC Daresbury Laboratory. pp 56-62.
-
(1993)
Data Collection and Processing. Proceedings of the CCP4 Study Weekend
, pp. 56-62
-
-
Otwinowski, Z.1
-
37
-
-
12944300317
-
Binding of nucleotides to proteins
-
Schulz GE. 1992. Binding of nucleotides to proteins. Curr Opin Struct Biol 2:61-67.
-
(1992)
Curr Opin Struct Biol
, vol.2
, pp. 61-67
-
-
Schulz, G.E.1
-
38
-
-
0026499283
-
L-thymidine is phosphorylated by Herpes simplex virus type 1 thymidine kinase and inhibits viral growth
-
Spadari S, Maga G, Focher F, Ciarrocchi G, Manservigi R, Arcamone F, Capobianco M, Caruro A, Colonna F, Iotti S, Garbesi A. 1992. L-thymidine is phosphorylated by Herpes simplex virus type 1 thymidine kinase and inhibits viral growth. J Med Chem 35:4214-4220.
-
(1992)
J Med Chem
, vol.35
, pp. 4214-4220
-
-
Spadari, S.1
Maga, G.2
Focher, F.3
Ciarrocchi, G.4
Manservigi, R.5
Arcamone, F.6
Capobianco, M.7
Caruro, A.8
Colonna, F.9
Iotti, S.10
Garbesi, A.11
-
39
-
-
0029036828
-
5-Iodo-2′-deoxy-L-uridine and (E)-5-(2-bromovinyl)-2′-deoxy-L-uridine: Elective phosphorylation by Herpes simplex virus type 1 thymidine kinase, antiherpetic activity, and cytotoxicity studies
-
Spadari S, Ciarrocchi G, Focher F, Verri A, Maga G, Arcamone F, Iafrate E, Manzini S, Garbesi A, Tondelli L. 1995. 5-Iodo-2′-deoxy-L-uridine and (E)-5-(2-bromovinyl)-2′-deoxy-L-uridine: elective phosphorylation by Herpes simplex virus type 1 thymidine kinase, antiherpetic activity, and cytotoxicity studies. Mol Pharmacol 47:1231-1238.
-
(1995)
Mol Pharmacol
, vol.47
, pp. 1231-1238
-
-
Spadari, S.1
Ciarrocchi, G.2
Focher, F.3
Verri, A.4
Maga, G.5
Arcamone, F.6
Iafrate, E.7
Manzini, S.8
Garbesi, A.9
Tondelli, L.10
-
40
-
-
0029994431
-
Crystal structure of bacteriophage T4 deoxynucleotide kinase with its substrates dGMP and ATP
-
Teplyakov A, Sebastiao P, Obmolova G, Perrakis A, Brush G, Bessman MJ, Wilson KS. 1996. Crystal structure of bacteriophage T4 deoxynucleotide kinase with its substrates dGMP and ATP. EMBO J 15:3487-3497.
-
(1996)
EMBO J
, vol.15
, pp. 3487-3497
-
-
Teplyakov, A.1
Sebastiao, P.2
Obmolova, G.3
Perrakis, A.4
Brush, G.5
Bessman, M.J.6
Wilson, K.S.7
-
41
-
-
0029644728
-
Movie of the structural changes during a catalytic cycle of nucleoside monophosphate kinases
-
Vonrhein C, Schlauderer GJ, Schulz GE. 1995. Movie of the structural changes during a catalytic cycle of nucleoside monophosphate kinases. Structure 3:483-490.
-
(1995)
Structure
, vol.3
, pp. 483-490
-
-
Vonrhein, C.1
Schlauderer, G.J.2
Schulz, G.E.3
-
42
-
-
0002032217
-
-
Roizmann B, Whitley RJ, Lopez C, eds. Raven, New York
-
Whitley RJ, Gnann JWG Jr. 1993. In: Roizmann B, Whitley RJ, Lopez C, eds. The human Herpesviruses. Raven, New York. pp 69-105.
-
(1993)
The Human Herpesviruses
, pp. 69-105
-
-
Whitley, R.J.1
Gnann Jr., J.W.G.2
-
43
-
-
0021971198
-
Prevention and control of Herpes virus diseases. Part 1. Clinical and laboratory diagnosis and chemotherapy
-
WHO Meeting
-
WHO Meeting. 1985. Prevention and control of Herpes virus diseases. Part 1. Clinical and laboratory diagnosis and chemotherapy. Bulletin of the WHO 63:182-185.
-
(1985)
Bulletin of the WHO
, vol.63
, pp. 182-185
-
-
-
44
-
-
0029020644
-
The three-dimensional structure of thymidine kinase from Herpes simplex virus type 1
-
Wild K, Bohner T, Aubry A, Folkers G, Schulz GE. 1995. The three-dimensional structure of thymidine kinase from Herpes simplex virus type 1. FEBS Lett 365:289-292.
-
(1995)
FEBS Lett
, vol.365
, pp. 289-292
-
-
Wild, K.1
Bohner, T.2
Aubry, A.3
Folkers, G.4
Schulz, G.E.5
|