Persistent expression of HNF6 in islet endocrine cells causes disrupted islet architecture and loss of beta cell function

Development

Volumn 127, Issue 13, 2000, Pages 2883-2895

  Gannon, Maureen ^a   Ray, Michael K ^a   Van Zee, Karla ^a   Rausa, Francisco ^b   Costa, Robert H ^b   Wright, Christopher V E ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Diabetes; HNF6; Islets; Mouse; Organogenesis; Pancreas; Transgenics

Indexed keywords

GLUCOSE; GLUCOSE TRANSPORTER; INSULIN; NUCLEAR FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; DIABETES MELLITUS; FEMALE; GENE EXPRESSION; GLUCOSE TOLERANCE TEST; HOMEOBOX; INSULIN BLOOD LEVEL; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; PANCREAS SECRETION; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; BETA-GALACTOSIDASE; CELL ADHESION; DIABETES MELLITUS, EXPERIMENTAL; DOWN-REGULATION; ENDOCRINE GLANDS; EYE; FLUORESCENT ANTIBODY TECHNIQUE; GLUCOSE; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORTER TYPE 2; GLYCOGEN; HEPATOCYTE NUCLEAR FACTOR 6; HOMEODOMAIN PROTEINS; IMMUNOHISTOCHEMISTRY; ISLETS OF LANGERHANS; LIVER; MICE; MICE, TRANSGENIC; MONOSACCHARIDE TRANSPORT PROTEINS; PANCREAS; PHENOTYPE; PROMOTER REGIONS (GENETICS); RADIOIMMUNOASSAY; TIME FACTORS; TRANS-ACTIVATORS;

ANIMALIA; MUS MUSCULUS;

EID: 0033930942     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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