Suppression of retinoic acid receptor β in non-small-cell lung cancer in vivo: Implications for lung cancer development

Journal of the National Cancer Institute

Volumn 89, Issue 9, 1997, Pages 624-629

  Xu, Xiao Chun ^a   Sozzi, Gabriella ^b   Lee, Jin S ^a   Lee, J Jack ^a   Pastorino, Ugo ^b   Pilotti, Silvana ^b   Kurie, Jonathan M ^a   Hong, Waun K ^a   Lotan, Reuben ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

RECEPTOR SUBTYPE; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR;

ADULT; AGED; ARTICLE; BRONCHUS MUCOSA; CONTROLLED STUDY; FEMALE; GENE REPRESSION; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; LUNG CARCINOGENESIS; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE;

EID: 0030997822     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/89.9.624     Document Type: Article

References (25)

1. Parker SL, Tong T, Bolden S, Wingo PA. Cancer Statistics, 1997. CA Cancer J Clin 1997;47:5-27.
2. Sporn MB, Newton DL. Chemoprevention of cancer with retinoids. Fed Proc 1979;38:2528-34.
3. Jetten AM, Nervi C, Vollberg TM. Control of squamous differentiation in tracheobronchial and epidermal epithelial cells: role of retinoids. Natl Cancer Inst Monog 1992;13:93-100.
4. Kelloff GJ, Boone CW, Steele VK, Perloff M, Crowell J, Doody LA. Development of chemopreventive agents for lung and upper aerodigestive tract cancers. J Cell Biochem Suppl 1993;17F:2-17.
5. Moon RC, Mehta RG, Rao KJ. Retinoids and cancer in experimental animals. In: Sporn MB, Roberts AB, Goodman DS, editors. The retinoids. New York: Raven Press, 1994:573-95.
6. Hong WK, Itri LM. Retinoids and human cancer. In: Sporn MB, Roberts AB, Goodman DS, editors. The retinoids. New York: Raven Press, 1994: 597-658.
7. Hong WK, Lippman SM, Hittelman WN, Lotan R. Retinoid chemoprevention of aerodigestive cancer: from basic research to the clinic. Clin Cancer Res 1995;1:677-86.
8. Pastorino U, Infante M, Maioli M, Chiesa G, Buyse M, Firket P, et al. Adjuvant treatment of stage 1 lung cancer with high-dose vitamin A. J Clin Oncol 1993;11:1216-22.
9. Chambon P. The retinoid signaling pathway: molecular and genetic analyses. Semin Cell Biol 1994;5:115-25.
10. Mangelsdorf DJ, Umesono K, Evans RM. The retinoid receptors. In: Sporn MB, Roberts AB, Goodman DS, editors. The retinoids. New York: Raven Press, 1994:319-49.
11. Pfahl M. Vertebrate receptors: molecular biology, dimerization and response elements. Semin Cell Biol 1994;5:95-103.
12. Geben JF, Moghal N, Frangioni JV, Sugarbaker DJ, Neel BG. High frequency of retinoic acid receptor beta abnormalities in human lung cancer [published erratum appears in Oncogene 1992;7:821]. Oncogene 1991;6: 1859-68.
13. Houle B, Leduc F, Bradley WE. Implication of RARB in epidermoid (squamous) lung cancer. Genes Chromosomes Cancer 1991;3:358-66.
14. Nervi C, Vollberg TM, George MD, Zelent A, Chambon P, Jetten AM. Expression of nuclear retinoic acid receptors in normal tracheobronchial cells and in lung carcinoma cells. Exp Cell Res 1991;195:163-70.
15. Geradts J, Chen JY, Russell EK, Yankaskas JR, Nieves L, Minna J. Human lung cancer cell lines exhibit resistance to retinoic acid treatment. Cell Growth Differ 1993;4:799-809.
16. Zhang XK, Liu Y, Lee MO, Pfahl M. A specific defect in the retinoic acid response associated with human lung cancer cell lines. Cancer Res 1994; 54:5663-9.
17. Moghal N, Neel BG. Evidence for impaired retinoic acid receptor-thyroid hormone receptor AF-2 cofactor activity in human lung cancer. Mol Cell Biol 1995;15:3945-59.
18. Houle B, Rochette-Egly C, Bradley WE. Tumor-suppressive effect of the retinoic acid receptor beta in human epidermoid lung cancer cells. Proc Natl Acad Sci U S A 1993;90:985-9.
19. Xu XC, Clifford JL, Hong WK, Lotan R. Detection of nuclear retinoic acid receptor mRNA in histological tissue sections using nonradioactive in situ hybridization histochemistry. Diag Mol Pathol 1994;3:122-31.
20. Xu XC, Ro JY, Lee JS, Shin DM, Hong WK, Lotan R. Differential expression of nuclear retinoic acid receptors in normal, premalignant, and malignant head and neck tissues. Cancer Res 1994;54:3580-7.
21. Lotan R, Xu XC, Lippman SM, Ro JY, Lee JS, Lee JJ, et al. Suppression of retinoic acid receptor-beta in oral premalignant lesions and its up-regulation by isotretinoin. N Engl J Med 1995;332:1405-10.
22. Denning MF, Verma AK. Involvement of retinoic acid nuclear receptors in retinoic acid-induced tissue transglutaminase gene expression in rat tracheal 2C5 cells. Biochem Biophys Res Commun 1991;175:344-50.
23. Ahn MJ, Langenfeld J, Moasser MM, Rusch V, Dmitrovsky E. Growth suppression of transformed human bronchial epithelial cells by all-trans-retinoic acid occurs through specific retinoid receptors. Oncogene 1995; 11:2357-64.
24. Berard J, Laboune F, Mukuna M, Masse S, Kothary R, Bradley WE. Lung tumors in mice expressing an antisense RARbeta2 transgene. FASEB J 1996;10:1091-7.
25. Oridate N, Esumi N, Lotan D, Hong WK, Rochette-Egly C, Chambon P, et al. Implication of retinoic acid receptor gamma in squamous differentiation and response to retinoic acid in head and neck SqCC/Y1 squamous carcinoma cells. Oncogene 1996;12:2019-28.