Enzyme/prodrug gene therapy approach for breast cancer using a recombinant adenovirus expressing Escherichia coli cytosine deaminase

Cancer Gene Therapy

Volumn 4, Issue 2, 1997, Pages 113-117

  Li, Zhuangwu ^a   Shanmugam, Naga ^a   Katayose, Dai ^a   Huber, Brian ^b   Srivastava, Shiv ^c   Cowan, Kenneth ^a   Seth, Prem ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b GLAXOSMITHKLINE   (United States)

^c UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

5 fluorocytosine; 5 fluorouracil; Cancer; Gene transfer; Nonmammalian enzyme; Suicide gene; Viral vectors

Indexed keywords

ANTIMETABOLITE; CYTOSINE DEAMINASE; DEAMINASE; FLUCYTOSINE; PRODRUG; RECOMBINANT PROTEIN;

ADENOVIRUS; ANIMAL; ARTICLE; BREAST TUMOR; CELL CULTURE; DRUG SCREENING; ENZYMOLOGY; ESCHERICHIA COLI; EXPERIMENTAL NEOPLASM; GENE THERAPY; GENETICS; HUMAN; METHODOLOGY; MOUSE; NUDE MOUSE; PATHOLOGY; VIROLOGY; XENOGRAFT;

ADENOVIRIDAE; ANIMALS; ANTIMETABOLITES; BREAST NEOPLASMS; CYTOSINE DEAMINASE; DRUG SCREENING ASSAYS, ANTITUMOR; ESCHERICHIA COLI; FLUCYTOSINE; GENE THERAPY; HUMANS; MICE; MICE, NUDE; NEOPLASMS, EXPERIMENTAL; NUCLEOSIDE DEAMINASES; PRODRUGS; RECOMBINANT PROTEINS; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0031087212     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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