From the growth cone surface to the cytoskeleton: One journey, many paths

Journal of Neurobiology

Volumn 44, Issue 2, 2000, Pages 184-193

  Mueller, Bernhard K ^a   Ledig, Matthias M ^a   Wahl, Siegfried ^a  

^a MAX PLANCK INSTITUTE FOR DEVELOPMENTAL BIOLOGY   (Germany)

Author keywords

Cytoskeleton; Ena VASP; Growth cone; Phosphatase; WASP

Indexed keywords

ACTIN; GUANOSINE TRIPHOSPHATASE; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; RHO FACTOR;

CYTOSKELETON; GROWTH CONE; HUMAN; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FAMILY; REVIEW; SIGNAL TRANSDUCTION;

ANIMAL; CYTOSKELETON; DNA-BINDING PROTEINS; GROWTH CONES; PROTEINS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0033868390     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-4695(200008)44:2<184::AID-NEU8>3.0.CO;2-N     Document Type: Review

References (104)

1. Identification of profilin and src homology 3 domains as binding partners for Drosophila enabled
2. Two GTPases Cdc42 and Rac bind directly to a protein implicated in the immunodeficiency disorder Wiscott-Aldrich syndrome
3. The Drosophila trio plays an essential role for patterning of axons by regulating their directional extension
4. PAK to the future
5. The guanine nucleotide exchange factor trio mediates axonal development in the Drosophila embryo
6. The two guanine nucleotide exchange factor domains of trio link the Rac 1 and the RhoA pathways in vivo
7. Disoriented pathfinding by pioneer neurone growth cones deprived of filopodia by cytochalasin treatment
8. NCAM-dependent neurite outgrowth is inhibited in neurons from Fyn-minus mice
9. Inhibition of tyrosine phosphorylation potentiates substrate-induced neurite growth
10. Distribution of profilin in fibroblasts correlates with the presence of highly dynamic actin filaments
11. Histology of the Nervous System
12. Control of neuronal pathway selection by a Drosophila receptor protein-tyrosine kinase family member
13. Inducible recruitment of Cdc42 or WASP to a cell surface receptor triggers actin polymerization and filopodium formation
14. The Dbl family of oncogenes
15. GTPase cascades choreographing cellular behavior: Movement morphogenesis and more
16. Navigational errors made by growth cones without filopodia in the embryonic Xenopus brain
17. Nineteenth-century origins of neuroscientific concepts
18. Chickadee encodes a profilin required for intercellular cytoplasm transport during Drosophila oogenesis
19. The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains
20. Receptor tyrosine phosphatases are required for motor axon guidance in the Drosophila embryo
21. Competition and cooperation among receptor tyrosine phosphatases control motoneuron growth cone guidance in Drosophila
22. Tyrosine phosphorylation and axon guidance: Of mice and flies
23. Neurite outgrowth stimulated by the tyrosine kinase inhibitor herbimycin-A requires activation of tyrosine kinases and protein-kinase-c
24. The ephrins and Eph receptors in neural development
25. Axon guidance: A balance of signals sets axons on the right track
26. Retinal axon target selection in Drosophila is regulated by a receptor protein tyrosine phosphatase
27. Drosophila abl tyrosine kinase in embryonic CNS axons: A role in axonogenesis is revealed through dosage-sensitive interactions with disabled
28. Enabled a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase encodes an Abl substrate with SH3 domain-binding properties
29. Genetic suppression of mutations in the Drosophila abl proto-oncogene homolog
30. Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics
31. Purification of profilin from Saccharomyces cervisiae and analysis of profilin-deficient cells
32. Molecular cloning structural analysis and functional expression of the proline-rich focal adhesion and microfilament-associated protein VASP
33. The cellular functions of small GTP-binding proteins
34. DNA Sequence structure and tyrosine kinase activity of the Drosophila melanogaster Abelson proto-oncogene homolog
35. The Drosophila abelson proto-oncogene homolog: Identification of mutant alleles that have pleiotropic effects late in development
36. A novel tyrosine kinase-independent function of Drosophila abl correlates with proper subcellular localization
37. Pak functions downstream of dock to regulate photoreceptor axon guidance in Drosophila
38. Juxtamembrane tyrosine residues couple EphB2/Nuk to specific SH2 domain proteins in neuronal cells
39. Binding of Nck to Sos and activation of ras-dependent gene expression
40. Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1
41. Drosophila Rac1 controls motor axon guidance
42. Rho family GTPases and neuronal growth cone remodeling: Relationships between increased complexity induced by Cdc42Hs Racl and acetylcholine and collapse induced by RhoA and lysophosphatidic acid
43. The transmembrane tyrosine phosphatase DLAR controls motor axon guidance in Drosophila
44. Requirement for mena in neurulation and commisure formation
45. From Abl to actin: Abl tyrosine kinase and associated proteins in growth cone motility
46. Role of proteins of the Ena/VASP family in actin-based motility of Listeria monocytogenes
47. 'Pull' and 'push' in neurite elongation: Observations on the effects of different concentrations of cytochalasin B and taxol
48. Beel, a yeast protein with homology to Wiscott-Aldrich Syndrome Protein, is critical for the assembly of cortical actin cytoskeleton
49. Dosage-sensitive reciprocal genetic interactions between the Abl tyrosine kinase and the putative guanine-nucleotide-exchange factor trio reveal a role in axon pathfinding
50. Cytoskeletal remodeling during growth cone-target interactions
51. Growth cone advance is inversely proportional to retrograde F-actin flow
52. Distinct morphogenetic functions of similar small GTPases: Drosophila Dracl is involved in axonal outgrowth and myoblast fusion
53. The Arp2/3 complex mediates actin polymerization induced by the small GTP-binding protein Cdc42
54. Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity-chromatography on profilin-agarose
55. Rho: A connection between membrane receptor signaling and the cytoskeleton
56. Scarl and the related Wiskott-Aldrich syndrome protein WASP regulate the actin cytoskeleton through the Arp2/3 complex
57. The mammalian Arp2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins
58. The intron-containing gene for yeast profilin (PFY) encodes a vital function
59. Profilin is required for posterior patterning of the Drosophila oocyte
60. Growth of neurites without filopodial or lamellipodial activity in the presence of cytochalasin B
61. Regulated actin cytoskeleton assembly at filopodium tips controls their extension rate and retraction
62. Inhibition of FGF receptor activity in retinal ganglion cell axons causes errors in target recognition
63. Genes necessary for directed axonai elongation or fasciculation in C. elegans
64. Tyrosine kinase inhibition produces specific alterations in axon guidance in the grasshopper embryo
65. N-WASP, a novel actin-polymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases
66. Induction of filopodium formation by a WASP-related actin-depoly-merizing protein N-WASP
67. Increased neurite outgrowth induced by inhibition of protein-tyrosine kinase-activity in PC-12 pheochromocytoma cells
68. Cytoskeletal dynamics and nerve growth
69. Growth cone guidance: First steps towards a deeper understanding
70. Arp2/3 complex from Acanthamoeba binds profillin and cross-links actin filaments
71. Rho-family GTPases require the Arp2/3 complex to stimulate actin polymerization in Acanthamoeba extracts
72. A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain a protein module present in the Ena/VASP family
73. Trio and Dock act combinatorially to activate Pak during photoreceptor axon guidance in Drosophila
74. Accumulation of actin in subsets of pioneer growth cone filopodia in response to neural and epithelial guidance cues in situ
75. The bacterial actin nucleator protein ActA of Listeria monocytogenes contains multiple binding sites for host micro-filament proteins
76. The interaction between N-WASP and the Arp 2/3 complex links Cdc42-dependent signals to actin assembly
77. A single growth cone is capable of integrating simultaneously presented and functionally distinct molecular cues during target recognition
78. VASP dynamics during lamellipodia protrusion
79. Still life, a protein in synaptic terminals of Drosophila homologous to GDP-GTP exchangers
80. Signal transduction underlying growth cone guidance by diffusible factors
81. Neurotactin functions in concert with other identified CAMs in growth cone guidance in Drosophila
82. Nck recruitment to Eph receptor EphB 1/Elk couples ligand activation to c-Jun kinase
83. Unc 73 Activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans
84. Protein tyrosine phosphatases and neural development
85. On the Crawling of Animal Cells
86. The essential role of profilin in the assembly of actin for microspike formation
87. An emerging link between cytoskeletal dynamics and cell adhesion molecules in growth cone guidance
88. Progress in protrusion: The tell-tale scar
89. Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia
90. The molecular biology of axon guidance
91. The three faces of profilin
92. Regulation of dendritic growth and remodeling by Rho, Rac, and Cdc42
93. Physical, immunochemical, and functional properties of Acanthamoeba profilin
94. Protein tyrosine phosphatases in the developing nervous system
95. Genes that control neuromuscular specificity in Drosophila
96. The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly
97. The tyrosine kinase Abi and its substrate enabled collaborate with the receptor phosphatase Dlar to control motor axon guidance
98. Profilin and the Abl tyrosine kinase are required for motor axon outgrowth in the Drosophila embryo
99. Genetic analysis of the mechanisms controlling target selection: Complementary and combinatorial functions of netrins, semaphorins, and IgCAMs
100. The complex containing actin-related proteins Arp2 and Arp3 is required for the motility and integrity of yeast actin patches
101. Inhibition of protein-tyrosine kinases impairs axon extension in the embryonic optic tract
102. Genes required for axon pathfinding and extension in the C. elegans nerve ring
103. Chemotaxis of macrophages is abolished in the Wiscott-Aldrich syndrome
104. Role of a new Rho family member in cell migration and axon guidance in C. elegans