메뉴 건너뛰기




Volumn 267, Issue 17, 2000, Pages 5298-5305

Symmetry and structure in P-glycoprotein and ABC transporters: What goes around comes around

Author keywords

ABC transporter; CFTR; Membrane topology; Multidrug resistance; P glycoprotein; Symmetry; TAP

Indexed keywords

ABC TRANSPORTER; GLYCOPROTEIN P;

EID: 0033864507     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2000.01628.x     Document Type: Review
Times cited : (33)

References (49)
  • 6
    • 0032698874 scopus 로고    scopus 로고
    • ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humans
    • (1999) J. Mol. Biol. , vol.293 , pp. 381-399
    • Holland, B.1    Blight, M.A.2
  • 9
    • 0022993652 scopus 로고
    • Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins
    • (1986) Cell , vol.47 , pp. 371-380
    • Gros, P.1    Croop, J.2    Housman, D.3
  • 12
    • 0029909604 scopus 로고    scopus 로고
    • Inhibition of oxidative cross-linking between engineered cysteine residues at positions 332 in predicted transmembrane segments (TM) 6 and 975 in predicted TM12 of human P-glycoprotein by drug substrates
    • (1996) J. Biol. Chem. , vol.271 , pp. 27482-27487
    • Loo, T.W.1    Clarke, D.M.2
  • 13
    • 0030779102 scopus 로고    scopus 로고
    • Drug-stimulated ATPase activity of human P-glycoprotein requires movement between transmembrane segments 6 and 12
    • (1997) J. Biol. Chem. , vol.272 , pp. 20986-20989
    • Loo, T.W.1    Clarke, D.M.2
  • 21
    • 0028921479 scopus 로고
    • Acetylcholine receptor channel imaged in the open state
    • (1995) Nature , vol.373 , pp. 37-43
    • Unwin, N.1
  • 27
    • 0033517099 scopus 로고    scopus 로고
    • Molecular interactions in ribose transport: The binding protein module symmetrically associates with the homodimeric membrane transporter
    • (1999) EMBO J , vol.18 , pp. 4149-4156
    • Park, Y.1    Cho, Y.-J.2    Ahn, T.3    Park, C.4
  • 29
  • 30
    • 0032700184 scopus 로고    scopus 로고
    • Determining the structure and mechanism of the human multidrug resistance P-glycoprotein using cysteine-scanning mutagenesis and thiol-modification techniques
    • (1999) Biochim. Biophys. Acta , vol.1461 , pp. 315-325
    • Loo, T.W.1    Clarke, D.M.2
  • 31
    • 0034051662 scopus 로고    scopus 로고
    • The packing of the transmembrane segments of human multidrug resistance P-glycoprotein is revealed by disulfide cross-linking analysis
    • (2000) J. Biol. Chem. , vol.275 , pp. 5253-5256
    • Loo, T.W.1    Clarke, D.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.