The heterotrimeric Gq protein-coupled angiotensin II receptor activates p21ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytes

EMBO Journal

Volumn 15, Issue 4, 1996, Pages 775-787

  Sadoshima, Jun Ichi ^a   Izumo, Seigo ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Angiotensin II; Fyn; Gq protein; Guanine nucleotide exchange activity; p21ras

Indexed keywords

METAZOA;

ANGIOTENSIN RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PERTUSSIS TOXIN; PROTEIN P21; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; HEART MUSCLE CELL; METAZOON; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR BINDING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANGIOTENSIN II; ANIMALS; CELLS, CULTURED; GTP-BINDING PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEART; MYOCARDIUM; PROTEIN-TYROSINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-FYN; PROTO-ONCOGENE PROTEINS P21(RAS); RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS; RATS; RATS, WISTAR; RECEPTORS, ANGIOTENSIN; SIGNAL TRANSDUCTION;

EID: 0029670826     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00413.x     Document Type: Article

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