A metabolic sensor in action: News from the ATP-sensitive K+-channel

News in Physiological Sciences

Volumn 12, Issue 6, 1997, Pages 255-262

  Trapp, S ^a   Ashcroft, F M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0031329429     PISSN: 08861714     EISSN: None     Source Type: Journal    
DOI: 10.1152/physiologyonline.1997.12.6.255     Document Type: Article

References (15)

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2. Ashcroft, F. M. Adenosine 5'-triphosphate-sensitive potassium channels. Annu. Rev. Neurosci. 11: 97-118, 1988.
3. ATP channel subunits. Neuron 18: 827-838, 1997.
4. Doupnik, C. A., N. Davidson, and H. A. Lester. The inward rectifier potassium channel family. Curr. Opin. Neurobiol. 5: 268-277, 1995.
5. Gribble, F. M., S. J. Tucker, and F. M. Ashcroft. The essential role of the Walker A motifs of SUR1 in K-ATP channel activation by Mg-ADP and diazoxide. EMBO J. 16: 1145-1152, 1997.
6. Higgins, C. F. The ABC of channel regulation. Cell 82: 693-696, 1995.
7. KATP: an inward rectifier subunit plus the sulfonylurea receptor. Science 270: 1166-1170, 1995.
8. + channels. Neuron 16: 1011-1017, 1996.
9. + channel. J. Biol. Chem. 271: 24321-24324, 1996.
10. ATP channels in pancreatic β-cells causes persistent hyperinsulinemic hypoglycemia of infancy. Nat. Med. 2: 1344-1347, 1996.
11. Nichols, C. G., S.-L. Shyng, A. Nestorowicz, B. Glaser, J. P. Clement IV, G. Gonzales, L. Aguilar-Bryan, M. A. Permutt, and J. Bryan. Adenosine diphosphate as an intracellular regulator of insulin secretion. Science 272: 1785-1787, 1996.
12. Sakura, H., C. Ämmälä, P. A. Smith, F. M. Gribble, and F. M. Ashcroft. Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic β-cells, brain, heart and skeletal muscle. FEBS Lett. 377: 338-344, 1995.
13. Thomas, P. M., G. J. Cote, N. Wohllk, B. Haddad, P. M. Mathew, W. Rabl, L. Aguilar-Bryan, R. F. Gagel, and J. Bryan. Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinaemic hypoglycaemia of infancy. Science 268: 425-429, 1995.
14. Trapp, S., S. J. Tucker, and F. M. Ashcroft. Activation and inhibition of K-ATP currents by guanine nucleotides is mediated by different channel subunits. Proc. Natl. Acad. Sci. USA 94: 8872-8877, 1997.
15. Tucker, S. J., F. M. Gribble, C. Zhao, S. Trapp, and F. M. Ashcroft. Truncation of Kir6.2 produces ATP-sensitive K-channels in the absence of the sulfonylurea receptor. Nature 387: 179-183, 1997.