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Volumn 335, Issue 21, 1996, Pages 1570-1580

Medical progress: Primary biliary cirrhosis

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHISTAMINIC AGENT; AUTOANTIBODY; AZATHIOPRINE; CIMETIDINE; COLCHICINE; COLESTIPOL; COLESTYRAMINE; CYCLOSPORIN; GLUCOCORTICOID; METHYLTESTOSTERONE; MITOCHONDRION ANTIBODY; NALOXONE; PENICILLAMINE; PHENOBARBITAL; PREDNISOLONE; PREDNISONE; RIFAMPICIN; URSODEOXYCHOLIC ACID; METHOTREXATE;

EID: 0030597246     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM199611213352107     Document Type: Review
Times cited : (513)

References (153)
  • 1
    • 0025266871 scopus 로고
    • The epidemiology of primary biliary cirrhosis in north-east England: An increasingly common disease?
    • Myszor M, James OF. The epidemiology of primary biliary cirrhosis in north-east England: an increasingly common disease? Q J Med 1990;75: 377-85.
    • (1990) Q J Med , vol.75 , pp. 377-385
    • Myszor, M.1    James, O.F.2
  • 2
    • 0023110737 scopus 로고
    • Primary biliary cirrhosis
    • Kaplan MM. Primary biliary cirrhosis. N Engl J Med 1987;316:521-8.
    • (1987) N Engl J Med , vol.316 , pp. 521-528
    • Kaplan, M.M.1
  • 4
    • 0025317299 scopus 로고
    • Epidemiology of primary biliary cirrhosis in a defined rural population in the northern part of Sweden
    • Danielsson A, Boqvist L, Uddenfeldt P Epidemiology of primary biliary cirrhosis in a defined rural population in the northern part of Sweden. Hepatology 1990;11:458-64.
    • (1990) Hepatology , vol.11 , pp. 458-464
    • Danielsson, A.1    Boqvist, L.2    Uddenfeldt, P.3
  • 5
    • 0025951983 scopus 로고
    • Descriptive epidemiology of primary biliary cirrhosis in the province of Quebec
    • Villeneuve J-P, Fenyves D, Infante-Rivard C. Descriptive epidemiology of primary biliary cirrhosis in the province of Quebec. Clin Gastroenterol 1991;5:174-8.
    • (1991) Clin Gastroenterol , vol.5 , pp. 174-178
    • Villeneuve, J.-P.1    Fenyves, D.2    Infante-Rivard, C.3
  • 6
    • 0028200735 scopus 로고
    • Familial primary biliary cirrhosis
    • Bach N, Schaffner F. Familial primary biliary cirrhosis. J Hepatol 1994; 20:698-701.
    • (1994) J Hepatol , vol.20 , pp. 698-701
    • Bach, N.1    Schaffner, F.2
  • 7
    • 0022624702 scopus 로고
    • Selective immunoglobulin A deficiency associated with primary biliary cirrhosis in a family with liver disease
    • James SP, Jones EA, Schafer DF, Hoofnagle JH, Varma RR, Strober W. Selective immunoglobulin A deficiency associated with primary biliary cirrhosis in a family with liver disease. Gastroenterology 1986;90:283-8.
    • (1986) Gastroenterology , vol.90 , pp. 283-288
    • James, S.P.1    Jones, E.A.2    Schafer, D.F.3    Hoofnagle, J.H.4    Varma, R.R.5    Strober, W.6
  • 8
    • 0016388662 scopus 로고
    • High prevalence of seroimmunologic abnormalities in relatives of patients with active chronic hepatitis or primary biliary cirrhosis
    • Galbraith RM, Smith M, Mackenzie RM, Tee DE, Doniach D, Williams R. High prevalence of seroimmunologic abnormalities in relatives of patients with active chronic hepatitis or primary biliary cirrhosis. N Engl J Med 1974;290:63-9.
    • (1974) N Engl J Med , vol.290 , pp. 63-69
    • Galbraith, R.M.1    Smith, M.2    Mackenzie, R.M.3    Tee, D.E.4    Doniach, D.5    Williams, R.6
  • 9
    • 0016804011 scopus 로고
    • Primary biliary cirrhosis
    • Schaffner F. Primary biliary cirrhosis. Clin Gastroenterol 1975;4:351-66.
    • (1975) Clin Gastroenterol , vol.4 , pp. 351-366
    • Schaffner, F.1
  • 12
    • 0026660952 scopus 로고
    • Antimitochondrial antibodies in kindreds of patients with primary biliary cirrhosis: Antimitochondrial antibodies are unique to clinical disease and are absent in asymptomatic family members
    • Caldwell SH, Leung PS, Spivey JR, et al. Antimitochondrial antibodies in kindreds of patients with primary biliary cirrhosis: antimitochondrial antibodies are unique to clinical disease and are absent in asymptomatic family members. Hepatology 1992;16:899-905.
    • (1992) Hepatology , vol.16 , pp. 899-905
    • Caldwell, S.H.1    Leung, P.S.2    Spivey, J.R.3
  • 13
    • 0026459598 scopus 로고
    • Susceptibility to primary biliary cirrhosis is associated with the HLA-DR8-DQB1*0402 haplotype
    • Underhill J, Donaldson P, Bray G, Doherty D, Portmann B, Williams R. Susceptibility to primary biliary cirrhosis is associated with the HLA-DR8-DQB1*0402 haplotype. Hepatology 1992;16:1404-8.
    • (1992) Hepatology , vol.16 , pp. 1404-1408
    • Underhill, J.1    Donaldson, P.2    Bray, G.3    Doherty, D.4    Portmann, B.5    Williams, R.6
  • 14
    • 0027252991 scopus 로고
    • Primary biliary cirrhosis: Contribution of HLA class II allele DR8
    • Gregory WL, Mehal W, Dunn AN, et al. Primary biliary cirrhosis: contribution of HLA class II allele DR8. Q J Med 1993;86:393-9.
    • (1993) Q J Med , vol.86 , pp. 393-399
    • Gregory, W.L.1    Mehal, W.2    Dunn, A.N.3
  • 15
    • 0028907743 scopus 로고
    • Association of primary biliary cirrhosis with the allele HLA-DPB1*0301 in a German population
    • Mella JG, Roschmann E, Maier KP, Volk BA. Association of primary biliary cirrhosis with the allele HLA-DPB1*0301 in a German population. Hepatology 1995;21:398-402.
    • (1995) Hepatology , vol.21 , pp. 398-402
    • Mella, J.G.1    Roschmann, E.2    Maier, K.P.3    Volk, B.A.4
  • 16
    • 0028939958 scopus 로고
    • HLA DPB polymorphism in primary sclerosing cholangitis and primary biliary cirrhosis
    • Underhill JA, Donaldson PT, Doherty DG, Manabc K, Williams R. HLA DPB polymorphism in primary sclerosing cholangitis and primary biliary cirrhosis. Hepatology 1995;21:959-62.
    • (1995) Hepatology , vol.21 , pp. 959-962
    • Underhill, J.A.1    Donaldson, P.T.2    Doherty, D.G.3    Manabc, K.4    Williams, R.5
  • 17
  • 18
    • 0026517987 scopus 로고
    • Nodular regen-erative hyperplasia of the liver in early, hisrcological stages of primary biliary cirrhosis
    • Colina. F, Pinedo F, Solis JA, Moreno D, Nevado M. Nodular regen-erative hyperplasia of the liver in early, hisrcological stages of primary biliary cirrhosis. Gastroenterology 1992;102:1319-24.
    • (1992) Gastroenterology , vol.102 , pp. 1319-1324
    • Colina, F.1    Pinedo, F.2    Solis, J.A.3    Moreno, D.4    Nevado, M.5
  • 19
    • 0024409191 scopus 로고
    • Lymphadenopathy in primary biliary cirrhosis: CT observations
    • Outwater E, Kaplan MM, Bankoff MS. Lymphadenopathy in primary biliary cirrhosis: CT observations. Radiology 1989;171:731-3.
    • (1989) Radiology , vol.171 , pp. 731-733
    • Outwater, E.1    Kaplan, M.M.2    Bankoff, M.S.3
  • 20
    • 84964193601 scopus 로고
    • Primary biliary cirrhosis
    • Scheuer P. Primary biliary cirrhosis. Proc R Soc Med 1967;60:1257-60.
    • (1967) Proc R Soc Med , vol.60 , pp. 1257-1260
    • Scheuer, P.1
  • 21
    • 0023632268 scopus 로고
    • New concepts in biliary cirrhosis
    • Ludwig J. New concepts in biliary cirrhosis. Semin Liver Dis 1987;7: 293-301.
    • (1987) Semin Liver Dis , vol.7 , pp. 293-301
    • Ludwig, J.1
  • 22
    • 0027141317 scopus 로고
    • Immunohistochemical characterization of hepatic lymphocytes in primary biliary cirrhosis in comparison with primary sclerosing cholangitis and autoimmune chronic active hepatitis
    • Hashimoto E, Lindor KD, Homburger HA, et al. Immunohistochemical characterization of hepatic lymphocytes in primary biliary cirrhosis in comparison with primary sclerosing cholangitis and autoimmune chronic active hepatitis. Mayo Clin Proc 1993;68:1049-55.
    • (1993) Mayo Clin Proc , vol.68 , pp. 1049-1055
    • Hashimoto, E.1    Lindor, K.D.2    Homburger, H.A.3
  • 23
    • 0027328383 scopus 로고
    • Distribution of B lymphocytes in nonsuppurative cholangitis in primary biliary cirrhosis
    • Nakanuma Y. Distribution of B lymphocytes in nonsuppurative cholangitis in primary biliary cirrhosis. Hepatology 1993;18:570-5.
    • (1993) Hepatology , vol.18 , pp. 570-575
    • Nakanuma, Y.1
  • 24
    • 0025323043 scopus 로고
    • Meyer zum Buschenfelde KH, Meuer SC. T cell receptor gene rearrangements of T lymphocytes infiltrating the liver in chronic active hepatitis B and primary biliary cirrhosis (PBC): Oligoclonality of PBC-derived T cell clones
    • Mocbius U, Manns M, Hess G, Kober G, Meyer zum Buschenfelde KH, Meuer SC. T cell receptor gene rearrangements of T lymphocytes infiltrating the liver in chronic active hepatitis B and primary biliary cirrhosis (PBC): oligoclonality of PBC-derived T cell clones. Eur J Immunol 1990; 20:889-96.
    • (1990) Eur J Immunol , vol.20 , pp. 889-896
    • Mocbius, U.1    Manns, M.2    Hess, G.3    Kober, G.4
  • 25
    • 0022339768 scopus 로고
    • The cellular pathology of primary biliary cirrhosis
    • MacSwecn RN, Burt AD. The cellular pathology of primary biliary cirrhosis. Mol Aspects Med 1985;8:269-91.
    • (1985) Mol Aspects Med , vol.8 , pp. 269-291
    • MacSwecn, R.N.1    Burt, A.D.2
  • 26
    • 0022517522 scopus 로고
    • In situ characterization of the cell-surface antigens of the mononuclcar cell infiltrate and bile duct epithelium in primary biliary cirrhosis
    • Colucci G, Schaffner F, Paronetto F. In situ characterization of the cell-surface antigens of the mononuclcar cell infiltrate and bile duct epithelium in primary biliary cirrhosis. Clin Immunol Immunopathol 1986;41:35-42.
    • (1986) Clin Immunol Immunopathol , vol.41 , pp. 35-42
    • Colucci, G.1    Schaffner, F.2    Paronetto, F.3
  • 27
    • 0028902868 scopus 로고
    • Immunohistochernical analysis or adhesion molecules in the microenvironment of portal tracts in relation to aberrant expression of PDC-E2 and HLA-DR on the bile ducts in primary biliary cirrhosis
    • Yasoshima M, Nakanuma Y, Tsuneyama K, Van de Water J, Gershwin ME. Immunohistochernical analysis or adhesion molecules in the microenvironment of portal tracts in relation to aberrant expression of PDC-E2 and HLA-DR on the bile ducts in primary biliary cirrhosis. J Pathol 1995; 175:319-25.
    • (1995) J Pathol , vol.175 , pp. 319-325
    • Yasoshima, M.1    Nakanuma, Y.2    Tsuneyama, K.3    Van De Water, J.4    Gershwin, M.E.5
  • 28
    • 0027319044 scopus 로고
    • Molecular mimicry in primary biliary cirrhosis: Evidence for biliary epithelial expression of a molecule cross-reactive with pyruvate dehydrogenase complex-E2
    • Van de Water J, Turchany J, Leung PS, et al. Molecular mimicry in primary biliary cirrhosis: evidence for biliary epithelial expression of a molecule cross-reactive with pyruvate dehydrogenase complex-E2. J Clin Invest 1993;91:2653-64.
    • (1993) J Clin Invest , vol.91 , pp. 2653-2664
    • Van De Water, J.1    Turchany, J.2    Leung, P.S.3
  • 29
    • 0021797766 scopus 로고
    • Sequential and diagnostic features in primary biliary cirrhosis based on serial histologic study in 209 patients
    • Portmann B, Popper H, Neuberger J, Williams R. Sequential and diagnostic features in primary biliary cirrhosis based on serial histologic study in 209 patients. Gastroenterology 1985;88:1777-90.
    • (1985) Gastroenterology , vol.88 , pp. 1777-1790
    • Portmann, B.1    Popper, H.2    Neuberger, J.3    Williams, R.4
  • 30
    • 0015620823 scopus 로고
    • Mallory's ('alcoholic') hyaline in primary biliary cirrhosis
    • MacSween RN. Mallory's ('alcoholic') hyaline in primary biliary cirrhosis. J Clin Pathol 1973;26:340-2.
    • (1973) J Clin Pathol , vol.26 , pp. 340-342
    • MacSween, R.N.1
  • 31
    • 0021794074 scopus 로고
    • Hepatic copper distribution in primary biliary cirrhosis shown by the scanning protein microprobE
    • Vaux DJ, Watt F, Grime GW, Takacs J. Hepatic copper distribution in primary biliary cirrhosis shown by the scanning protein microprobE. J Clin Pathol 1985;38:653-8.
    • (1985) J Clin Pathol , vol.38 , pp. 653-658
    • Vaux, D.J.1    Watt, F.2    Grime, G.W.3    Takacs, J.4
  • 32
    • 0028005374 scopus 로고
    • Hepatic copper content is normal in early primary biliary cirrhosis and primary sclerosing cholangitis
    • Kowdley KV, Knox TA, Kaplan MM. Hepatic copper content is normal in early primary biliary cirrhosis and primary sclerosing cholangitis. Dig Dis Sci 1994;39:2416-20.
    • (1994) Dig Dis Sci , vol.39 , pp. 2416-2420
    • Kowdley, K.V.1    Knox, T.A.2    Kaplan, M.M.3
  • 33
    • 0026034491 scopus 로고
    • Primary biliary cirrhosis: Paradigm or paradox for autoimmunity
    • Gershwin ME, Mackay IR. Primary biliary cirrhosis: paradigm or paradox for autoimmunity. Gastroenterology 1991;100:822-33.
    • (1991) Gastroenterology , vol.100 , pp. 822-833
    • Gershwin, M.E.1    Mackay, I.R.2
  • 35
    • 0019989377 scopus 로고
    • IgM in primary biliary cirrhosis: Physicochemical and complement activating properties
    • Lindgren S, Eriksson S. IgM in primary biliary cirrhosis: physicochemical and complement activating properties. J Lab Clin Med 1982;99:636-45.
    • (1982) J Lab Clin Med , vol.99 , pp. 636-645
    • Lindgren, S.1    Eriksson, S.2
  • 37
    • 0017045373 scopus 로고
    • Immune response to phi X 174 in man. 5. Primary and secondary antibody production in primary biliary cirrhosis
    • Thomas HC, Holden R, Jones JV, Peacock DB. Immune response to phi X 174 in man. 5. Primary and secondary antibody production in primary biliary cirrhosis. Gut 1976;17:844-8.
    • (1976) Gut , vol.17 , pp. 844-848
    • Thomas, H.C.1    Holden, R.2    Jones, J.V.3    Peacock, D.B.4
  • 38
    • 0021795205 scopus 로고
    • Complement activation in primary biliary cirrhosis: An in vitro model
    • Lindgren S, Johnson U. Complement activation in primary biliary cirrhosis: an in vitro model. J Lab Clin Med 1985;105:432-5.
    • (1985) J Lab Clin Med , vol.105 , pp. 432-435
    • Lindgren, S.1    Johnson, U.2
  • 41
    • 0025101026 scopus 로고
    • Low molecular weight IgM in primary biliary cirrhosis
    • Roberts-Thomson PJ, Shepherd K. Low molecular weight IgM in primary biliary cirrhosis. Gut 1990;31:88-91.
    • (1990) Gut , vol.31 , pp. 88-91
    • Roberts-Thomson, P.J.1    Shepherd, K.2
  • 44
    • 50549218780 scopus 로고
    • Serological tests in diagnosis of primary biliary cirrhosis
    • Walker JG, Doniach D, Roitt IM, Sherlock S. Serological tests in diagnosis of primary biliary cirrhosis. Lancet 1965;1:827-31.
    • (1965) Lancet , vol.1 , pp. 827-831
    • Walker, J.G.1    Doniach, D.2    Roitt, I.M.3    Sherlock, S.4
  • 45
    • 0024348516 scopus 로고
    • Detection of autoantibodies to recombinant mitochondrial proteins in patients with primary biliary cirrhosis
    • Van de Water J, Cooper A, Surh CD, et al. Detection of autoantibodies to recombinant mitochondrial proteins in patients with primary biliary cirrhosis. N Engl J Med 1989;320;1377-80.
    • (1989) N Engl J Med , vol.320 , pp. 1377-1380
    • Van De Water, J.1    Cooper, A.2    Surh, C.D.3
  • 46
    • 0029082348 scopus 로고
    • Autoantibodies from patients with primary biliary cirrhosis preferentially react with the amino-terminal domain of nuclear pore complex glycoprotein gp210
    • Wesierska-Gadek J, Hohenauer H, Hitchman E, Penner E. Autoantibodies from patients with primary biliary cirrhosis preferentially react with the amino-terminal domain of nuclear pore complex glycoprotein gp210. J Exp Med 1995;182:1159-62.
    • (1995) J Exp Med , vol.182 , pp. 1159-1162
    • Wesierska-Gadek, J.1    Hohenauer, H.2    Hitchman, E.3    Penner, E.4
  • 49
    • 0021798833 scopus 로고
    • Anti-acetylcholine receptor antibodies in primary biliary cirrhosis
    • Sundewall AC, Lefvert AK, Olsson R. Anti-acetylcholine receptor antibodies in primary biliary cirrhosis. Acta Med Scand 1985;217:519-25.
    • (1985) Acta Med Scand , vol.217 , pp. 519-525
    • Sundewall, A.C.1    Lefvert, A.K.2    Olsson, R.3
  • 50
    • 0022398057 scopus 로고
    • Platelet associated immunoglobulins in primary biliary cirrhosis: A cause of thrombocytopenia?
    • Bassendine MF, Collins JD, Stephenson J, Saunders P, James OF. Platelet associated immunoglobulins in primary biliary cirrhosis: a cause of thrombocytopenia? Gut 1985;26:1074-9.
    • (1985) Gut , vol.26 , pp. 1074-1079
    • Bassendine, M.F.1    Collins, J.D.2    Stephenson, J.3    Saunders, P.4    James, O.F.5
  • 51
    • 0022618681 scopus 로고
    • Demonstration of immune complexes containing the ribonucleoprotein antigen Ro in primary biliary cirrhosis
    • Penner E. Demonstration of immune complexes containing the ribonucleoprotein antigen Ro in primary biliary cirrhosis. Gastroenterology 1986;90:724-7.
    • (1986) Gastroenterology , vol.90 , pp. 724-727
    • Penner, E.1
  • 52
    • 0023193321 scopus 로고
    • High prevalence of antibodies to histones among patients with primary biliary cirrhosis
    • Penner E, Muller S, Zimmermann D, Van Regenmortel MH. High prevalence of antibodies to histones among patients with primary biliary cirrhosis. Clin Exp Immunol 1987;70:47-52.
    • (1987) Clin Exp Immunol , vol.70 , pp. 47-52
    • Penner, E.1    Muller, S.2    Zimmermann, D.3    Van Regenmortel, M.H.4
  • 53
    • 0029143661 scopus 로고
    • High prevalence of antibodies to recombinant CENP-B in primary biliary cirrhosis: Nuclear immunotluorescence patterns and ELISA reactivities
    • Parveen S, Morshed SA, Nishioka M. High prevalence of antibodies to recombinant CENP-B in primary biliary cirrhosis: nuclear immunotluorescence patterns and ELISA reactivities. J Gastroenterol Hepatol 1995;10: 438-45.
    • (1995) J Gastroenterol Hepatol , vol.10 , pp. 438-445
    • Parveen, S.1    Morshed, S.A.2    Nishioka, M.3
  • 54
    • 0019971123 scopus 로고
    • Evidence against an immune complex pathogenesis of primary biliary cirrhosis
    • Goldberg MJ, Kaplan MM, Mitamura T, et al. Evidence against an immune complex pathogenesis of primary biliary cirrhosis. Gastrocntcrology 1982;83:677-83.
    • (1982) Gastrocntcrology , vol.83 , pp. 677-683
    • Goldberg, M.J.1    Kaplan, M.M.2    Mitamura, T.3
  • 56
    • 0019135056 scopus 로고
    • Deficiency of the autologous mixed lymphocyte reaction in patients with primary biliary cirrhosis
    • James SP, Elson CO, Waggoner JG, Jones EA, Strober W. Deficiency of the autologous mixed lymphocyte reaction in patients with primary biliary cirrhosis. J Clin Invest 1980;66:1305-10.
    • (1980) J Clin Invest , vol.66 , pp. 1305-1310
    • James, S.P.1    Elson, C.O.2    Waggoner, J.G.3    Jones, E.A.4    Strober, W.5
  • 57
    • 0028177187 scopus 로고
    • Reduced numbers of CD8+ T cells and B cell-expression of Leu-8 antigen in peripheral blood of patients with primary biliary cirrhosis
    • Moreno-Otero R, Civeira MP, Suou T, Kanof ME, James SP, Jones EA. Reduced numbers of CD8+ T cells and B cell-expression of Leu-8 antigen in peripheral blood of patients with primary biliary cirrhosis. Hepatogastroenterology 1994;41:239-43.
    • (1994) Hepatogastroenterology , vol.41 , pp. 239-243
    • Moreno-Otero, R.1    Civeira, M.P.2    Suou, T.3    Kanof, M.E.4    James, S.P.5    Jones, E.A.6
  • 58
    • 0024343728 scopus 로고
    • Detective immunoregulation in primary biliary cirrhosis: CD4+, Leu-8+ T cells have abnormal activation and suppressor function in vitro
    • Suou T, Civeira MP, Kanof ME, Moreno-Otero R, Jones EA, James SP. Detective immunoregulation in primary biliary cirrhosis: CD4+, Leu-8+ T cells have abnormal activation and suppressor function in vitro. Hepatology 1989;10:408-13.
    • (1989) Hepatology , vol.10 , pp. 408-413
    • Suou, T.1    Civeira, M.P.2    Kanof, M.E.3    Moreno-Otero, R.4    Jones, E.A.5    James, S.P.6
  • 59
    • 0026728146 scopus 로고
    • Deficient interleukin-2 responsiveness of T lymphocytes from patients with primary biliary cirrhosis
    • Menendez JL, Giron JA, Manzano L, et al. Deficient interleukin-2 responsiveness of T lymphocytes from patients with primary biliary cirrhosis. Hepatology 1992;16:931-6.
    • (1992) Hepatology , vol.16 , pp. 931-936
    • Menendez, J.L.1    Giron, J.A.2    Manzano, L.3
  • 60
    • 0026773221 scopus 로고
    • T lymphocytes from patients with primary biliary cirrhosis produce reduced amounts of lymphotoxins, tumor necrosis factor and Interferon-gamma upon mitogen stimulation
    • Spengler U, Moller A, Jung MC, et al. T lymphocytes from patients with primary biliary cirrhosis produce reduced amounts of lymphotoxins, tumor necrosis factor and Interferon-gamma upon mitogen stimulation. J Hepatol 1992;15:129-35.
    • (1992) J Hepatol , vol.15 , pp. 129-135
    • Spengler, U.1    Moller, A.2    Jung, M.C.3
  • 61
    • 0026034298 scopus 로고
    • Evidence for the targeting by 2-oxo-dehydrogenase enzymes in the T cell response of primary biliary cirrhosis
    • Van de Water J, Ansari AA, Surh CD, et al. Evidence for the targeting by 2-oxo-dehydrogenase enzymes in the T cell response of primary biliary cirrhosis. J Immunol 1991;146:89-94.
    • (1991) J Immunol , vol.146 , pp. 89-94
    • Van De Water, J.1    Ansari, A.A.2    Surh, C.D.3
  • 62
    • 0028901610 scopus 로고
    • T-cell responses to the components of pyruvate dehydrogenase complex in primary biliary cirrhosis
    • Jones DE, Palmer JM, James OF, Yeaman SJ, Bassendine MF, Diamond AG. T-cell responses to the components of pyruvate dehydrogenase complex in primary biliary cirrhosis. Hepatology 1995;21:995-1002.
    • (1995) Hepatology , vol.21 , pp. 995-1002
    • Jones, D.E.1    Palmer, J.M.2    James, O.F.3    Yeaman, S.J.4    Bassendine, M.F.5    Diamond, A.G.6
  • 63
    • 0028914413 scopus 로고
    • T cell autoreactivity against a 28 kD biliary protein (B1-p28) in primary biliary cirrhosis
    • Miyamoto T, Maeda T, Onishi S, Yamamoto Y. T cell autoreactivity against a 28 kD biliary protein (B1-p28) in primary biliary cirrhosis. J Hepatol 1995;22:423-30.
    • (1995) J Hepatol , vol.22 , pp. 423-430
    • Miyamoto, T.1    Maeda, T.2    Onishi, S.3    Yamamoto, Y.4
  • 64
    • 0002819858 scopus 로고
    • Primary structure of the human M2 mitochondrial autoantigen of primary biliary cirrhosis: Dihydrolipoamide acetyltransferase
    • Coppel RL, McNeilage LJ, Surh CD, et al. Primary structure of the human M2 mitochondrial autoantigen of primary biliary cirrhosis: dihydrolipoamide acetyltransferase. Proc Natl Acad Sci U S A 1988;85:7317-21.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 7317-7321
    • Coppel, R.L.1    McNeilage, L.J.2    Surh, C.D.3
  • 65
    • 0023813733 scopus 로고
    • Autoantibodies of primary biliary cirrhosis recognize dihydrolipoamide acetyltransferase and inhibit enzyme function
    • Van de Water J, Fregeau D, Davis P, et al. Autoantibodies of primary biliary cirrhosis recognize dihydrolipoamide acetyltransferase and inhibit enzyme function. J Immunol 1988;141:2321-4.
    • (1988) J Immunol , vol.141 , pp. 2321-2324
    • Van De Water, J.1    Fregeau, D.2    Davis, P.3
  • 66
    • 0026463551 scopus 로고
    • M4 and M9 antibodies in the overlap syndrome of primary biliary cirrhosis and chronic active hepatitis: Epitopes or epiphenomena?
    • Davis PA, Leung P, Manns M, et al. M4 and M9 antibodies in the overlap syndrome of primary biliary cirrhosis and chronic active hepatitis: epitopes or epiphenomena? Hepatology 1992;16:1128-36.
    • (1992) Hepatology , vol.16 , pp. 1128-1136
    • Davis, P.A.1    Leung, P.2    Manns, M.3
  • 67
    • 0027303385 scopus 로고
    • M4 and M9 autoantigens in primary biliary cirrhosis - A negative study
    • Palmer JM, Yeaman SJ, Bassendine MF, James OF. M4 and M9 autoantigens in primary biliary cirrhosis - a negative study. J Hepatol 1993;18: 251-4.
    • (1993) J Hepatol , vol.18 , pp. 251-254
    • Palmer, J.M.1    Yeaman, S.J.2    Bassendine, M.F.3    James, O.F.4
  • 68
    • 0024503374 scopus 로고
    • Immunization of experimental animals with dihydrolipoamide acetyl-transferase, as a purified recombinant polypeptide, generates mitochondrial antibodies but not primary biliary cirrhosis
    • Krams SM, Surh CD, Coppel RL, Ansari A, Ruebner B, Gershwin ME. Immunization of experimental animals with dihydrolipoamide acetyl-transferase, as a purified recombinant polypeptide, generates mitochondrial antibodies but not primary biliary cirrhosis. Hepatology 1989;9:411-6.
    • (1989) Hepatology , vol.9 , pp. 411-416
    • Krams, S.M.1    Surh, C.D.2    Coppel, R.L.3    Ansari, A.4    Ruebner, B.5    Gershwin, M.E.6
  • 69
    • 0024517904 scopus 로고
    • Characterisation of the reactivity of autoantibodies in primary biliary cirrhosis
    • Fussey SP, Bassendine MF, James OF, Yeaman SJ. Characterisation of the reactivity of autoantibodies in primary biliary cirrhosis. FEBS Lett 1989;246:49-53.
    • (1989) FEBS Lett , vol.246 , pp. 49-53
    • Fussey, S.P.1    Bassendine, M.F.2    James, O.F.3    Yeaman, S.J.4
  • 71
    • 0028883895 scopus 로고
    • Primary biliary cirrhosis induced by interferon-alpha therapy for hepatitis C virus infection
    • D'Amico E, Paroli M, Fratelli V, et al. Primary biliary cirrhosis induced by interferon-alpha therapy for hepatitis C virus infection. Dig Dis Sci 1995;40:2113-6.
    • (1995) Dig Dis Sci , vol.40 , pp. 2113-2116
    • D'Amico, E.1    Paroli, M.2    Fratelli, V.3
  • 72
    • 0028007158 scopus 로고
    • Chlorpromazine-induced vanishing bile duct syndrome leading to biliary cirrhosis
    • Moradpour D, Altorfer J, Flury R, et al. Chlorpromazine-induced vanishing bile duct syndrome leading to biliary cirrhosis. Hepatology 1994; 20:1437-41.
    • (1994) Hepatology , vol.20 , pp. 1437-1441
    • Moradpour, D.1    Altorfer, J.2    Flury, R.3
  • 73
    • 0028939963 scopus 로고
    • Abnormal expression of the E2 component of the pyruvate dehydrogenase complex on the luminal surface of biliary epithelium occurs before major histoeompatibility complex class II and BB1/B7 expression
    • Tsuneyama K, Van de Water J, Leung PS, et al. Abnormal expression of the E2 component of the pyruvate dehydrogenase complex on the luminal surface of biliary epithelium occurs before major histoeompatibility complex class II and BB1/B7 expression. Hepatology 1995;21:1031-7.
    • (1995) Hepatology , vol.21 , pp. 1031-1037
    • Tsuneyama, K.1    Van De Water, J.2    Leung, P.S.3
  • 75
    • 0025790578 scopus 로고
    • Conjugates of ursodeoxycholate protect against cytotoxicity of more Hydrophobic bile salts: In vitro studies in rat hepatocytes and human crythrocyres
    • Heuman DM, Pandak WM, Hylemon PB, Vlahcevic ZR. Conjugates of ursodeoxycholate protect against cytotoxicity of more Hydrophobic bile salts: in vitro studies in rat hepatocytes and human crythrocyres. Hepatology 1991;14:920-6.
    • (1991) Hepatology , vol.14 , pp. 920-926
    • Heuman, D.M.1    Pandak, W.M.2    Hylemon, P.B.3    Vlahcevic, Z.R.4
  • 76
    • 0015937531 scopus 로고
    • The presentation and diagnosis of 100 patients with primary biliary cirrhosis
    • Sherlock S, Scheuer PJ. The presentation and diagnosis of 100 patients with primary biliary cirrhosis. N Engl J Med 1973;289:674-8.
    • (1973) N Engl J Med , vol.289 , pp. 674-678
    • Sherlock, S.1    Scheuer, P.J.2
  • 77
    • 0017735380 scopus 로고
    • Presentation and course of asymptomatic primary biliary cirrhosis
    • Long RG, Scheuer PJ, Sherlock S. Presentation and course of asymptomatic primary biliary cirrhosis. Gastroenterology 1977;72:1204-7.
    • (1977) Gastroenterology , vol.72 , pp. 1204-1207
    • Long, R.G.1    Scheuer, P.J.2    Sherlock, S.3
  • 79
    • 0018963775 scopus 로고
    • Primary biliary cirrhosis: Natural history
    • Tornay AS Jr. Primary biliary cirrhosis: natural history. Am J Gastroenrerol 1980;73:223-6.
    • (1980) Am J Gastroenrerol , vol.73 , pp. 223-226
    • Tornay Jr., A.S.1
  • 80
    • 0017691040 scopus 로고
    • Elevations in skin tissue levels of bile acids in human cholestasis: Relation to serum levels and to pruritus
    • Ghent CN, Bloomer JR, Klatskin G. Elevations in skin tissue levels of bile acids in human cholestasis: relation to serum levels and to pruritus. Gastroenterology 1977;73:1125-30.
    • (1977) Gastroenterology , vol.73 , pp. 1125-1130
    • Ghent, C.N.1    Bloomer, J.R.2    Klatskin, G.3
  • 81
    • 0026603330 scopus 로고
    • A controlled trial of naloxone infusions for the pruritus of chronic cholestasis
    • Bergasa NV, Talbot TL, Alling DW, et al. A controlled trial of naloxone infusions for the pruritus of chronic cholestasis. Gastroenterology 1992;102:544-9.
    • (1992) Gastroenterology , vol.102 , pp. 544-549
    • Bergasa, N.V.1    Talbot, T.L.2    Alling, D.W.3
  • 83
    • 0018835294 scopus 로고
    • Clinical pattern and course of disease in primary biliary cirrhosis based on an analysis of 236 patients
    • Christensen E, Crowo J, Doniach D, et al. Clinical pattern and course of disease in primary biliary cirrhosis based on an analysis of 236 patients. Gastroenterology 1980;78:236-46.
    • (1980) Gastroenterology , vol.78 , pp. 236-246
    • Christensen, E.1    Crowo, J.2    Doniach, D.3
  • 87
    • 0027634159 scopus 로고
    • Elective cholecystectomy in selected cirrhotic patients
    • Iannuzzi C, Cozzolino G, Negro G. Elective cholecystectomy in selected cirrhotic patients. Acta Chir Belg 1993;93:147-50.
    • (1993) Acta Chir Belg , vol.93 , pp. 147-150
    • Iannuzzi, C.1    Cozzolino, G.2    Negro, G.3
  • 88
    • 0022414583 scopus 로고
    • Lipoprotein abnormalities in primary biliary cirrhosis: Association with hepatic lipase inhibition as well as altered cholesterol esterification
    • Jahn CE, Schacfer EJ, Taam LA, et al. Lipoprotein abnormalities in primary biliary cirrhosis: association with hepatic lipase inhibition as well as altered cholesterol esterification. Gastroenterology 1985;89:1266-78.
    • (1985) Gastroenterology , vol.89 , pp. 1266-1278
    • Jahn, C.E.1    Schacfer, E.J.2    Taam, L.A.3
  • 89
    • 0026587929 scopus 로고
    • Hypercholesteroleniia and atherosclerosis in primary biliary cirrhosis: What is the risk?
    • Crippin JS, Lindor KD, Jorgensen R, et al. Hypercholesteroleniia and atherosclerosis in primary biliary cirrhosis: what is the risk? Hepatology 1992;15:858-62.
    • (1992) Hepatology , vol.15 , pp. 858-862
    • Crippin, J.S.1    Lindor, K.D.2    Jorgensen, R.3
  • 91
    • 0017810533 scopus 로고
    • Lipoprotein-X levels in extrahepatic versus intrahepatic cholestasis
    • Simon JR, Poon RW. Lipoprotein-X levels in extrahepatic versus intrahepatic cholestasis. Gastroenterology 1978;75:177-80.
    • (1978) Gastroenterology , vol.75 , pp. 177-180
    • Simon, J.R.1    Poon, R.W.2
  • 92
    • 0027537002 scopus 로고
    • Cholesterol-lowering effect of ursodeoxycholic acid in patients with primary biliary cirrhosis
    • Poupon RE, Ougucrram K, Chretien Y, et al. Cholesterol-lowering effect of ursodeoxycholic acid in patients with primary biliary cirrhosis. Hepatology 1993;17:577-82.
    • (1993) Hepatology , vol.17 , pp. 577-582
    • Poupon, R.E.1    Ougucrram, K.2    Chretien, Y.3
  • 93
    • 0028107704 scopus 로고
    • Predictive factors in ursodeoxycholic acid-treated patients with primary biliary cirrhosis: Role of serum markers of connective tissue
    • Poupon RE, Balkau B, Guechot J, Heintzmann F. Predictive factors in ursodeoxycholic acid-treated patients with primary biliary cirrhosis: role of serum markers of connective tissue. Hepatology 1994;19:635-40.
    • (1994) Hepatology , vol.19 , pp. 635-640
    • Poupon, R.E.1    Balkau, B.2    Guechot, J.3    Heintzmann, F.4
  • 94
    • 0023894907 scopus 로고
    • High incidence of poor sulfoxidation in patients with primary biliary cirrhosis
    • Olornu AB, Vickers CR, Waring RH, et al. High incidence of poor sulfoxidation in patients with primary biliary cirrhosis. N Engl J Med 1988; 318:1089-92.
    • (1988) N Engl J Med , vol.318 , pp. 1089-1092
    • Olornu, A.B.1    Vickers, C.R.2    Waring, R.H.3
  • 95
    • 0029000665 scopus 로고
    • Sulphoxidation and sulphation capacity in patients with primary biliary cirrhosis
    • Davics MH, Ngong JM, Pean A, Vickers CR, Waring RH, Elias E. Sulphoxidation and sulphation capacity in patients with primary biliary cirrhosis. J Hepatol 1995;22:551-60.
    • (1995) J Hepatol , vol.22 , pp. 551-560
    • Davics, M.H.1    Ngong, J.M.2    Pean, A.3    Vickers, C.R.4    Waring, R.H.5    Elias, E.6
  • 96
    • 0021269281 scopus 로고
    • Fat digestion and exocrine pancreatic function in primary biliary cirrhosis
    • Ros E, Garcia-Puges A, Reixach M, Cuso E, Rodes J. Fat digestion and exocrine pancreatic function in primary biliary cirrhosis. Gastroenterology 1984;87:180-7.
    • (1984) Gastroenterology , vol.87 , pp. 180-187
    • Ros, E.1    Garcia-Puges, A.2    Reixach, M.3    Cuso, E.4    Rodes, J.5
  • 98
    • 0015023096 scopus 로고
    • Primary biliary cirrhosis with scleroderma, Raynaud's phenomenon and telangiectasia: New syndrome
    • Reynolds TB, Denison EK, Frankl HD, Lieberman FL, Peters RL. Primary biliary cirrhosis with scleroderma, Raynaud's phenomenon and telangiectasia: new syndrome. Am J Med 1971;50:302-12.
    • (1971) Am J Med , vol.50 , pp. 302-312
    • Reynolds, T.B.1    Denison, E.K.2    Frankl, H.D.3    Lieberman, F.L.4    Peters, R.L.5
  • 99
    • 0025192029 scopus 로고
    • Sjogren's syndrome in patients with primary biliary cirrhosis
    • Tsianos EV, Hoofnagle JH, Fox PC, et al. Sjogren's syndrome in patients with primary biliary cirrhosis. Hepatology 1990;11:730-4.
    • (1990) Hepatology , vol.11 , pp. 730-734
    • Tsianos, E.V.1    Hoofnagle, J.H.2    Fox, P.C.3
  • 101
    • 0018172615 scopus 로고
    • Increased serum thyroid hormone binding and decreased free hormone in chronic active liver disease
    • Schussler GC, Schaffner F, Korn F. Increased serum thyroid hormone binding and decreased free hormone in chronic active liver disease. N Engl J Med 1978;299:510-5.
    • (1978) N Engl J Med , vol.299 , pp. 510-515
    • Schussler, G.C.1    Schaffner, F.2    Korn, F.3
  • 103
    • 0028365234 scopus 로고
    • Cancer risk in primary biliary cirrhosis: A population-based study from Sweden
    • Loof L, Adami HO, Sparen P, et al. Cancer risk in primary biliary cirrhosis: a population-based study from Sweden. Hepatology 1994;20: 101-4.
    • (1994) Hepatology , vol.20 , pp. 101-104
    • Loof, L.1    Adami, H.O.2    Sparen, P.3
  • 104
    • 0025300411 scopus 로고
    • The demography of primary biliary cirrhosis in Ontario, Canada
    • Witt-Sullivan H, Heathcote J, Cauch K, et al. The demography of primary biliary cirrhosis in Ontario, Canada. Hepatology 1990;12:98-105.
    • (1990) Hepatology , vol.12 , pp. 98-105
    • Witt-Sullivan, H.1    Heathcote, J.2    Cauch, K.3
  • 105
    • 0029016571 scopus 로고
    • Natural history of bacteriuria in women with primary biliary cirrhosis and the effect of antimicrobial therapy in symptomatic and asymptomatic groups
    • Butler P, Hamilton-Miller JM, McIntyre N, Burroughs AK. Natural history of bacteriuria in women with primary biliary cirrhosis and the effect of antimicrobial therapy in symptomatic and asymptomatic groups. Gut 1995;36:931-4.
    • (1995) Gut , vol.36 , pp. 931-934
    • Butler, P.1    Hamilton-Miller, J.M.2    McIntyre, N.3    Burroughs, A.K.4
  • 108
    • 0029050523 scopus 로고
    • Role of hyperbilirubinemia in the impairment of osteoblast proliferation associated with cholestatic jaundice
    • Janes CH, Dickson ER, Okazaki R, Bonde S, McDonagh AF, Riggs BL. Role of hyperbilirubinemia in the impairment of osteoblast proliferation associated with cholestatic jaundice. J Clin Invest 1995;95:2581-6.
    • (1995) J Clin Invest , vol.95 , pp. 2581-2586
    • Janes, C.H.1    Dickson, E.R.2    Okazaki, R.3    Bonde, S.4    McDonagh, A.F.5    Riggs, B.L.6
  • 109
    • 0020075621 scopus 로고
    • Bone disease in primary biliary cirrhosis: Histologic features and response to 25-hydroxyvitamin D
    • Herlong HF, Recker RR, Maddrey WC. Bone disease in primary biliary cirrhosis: histologic features and response to 25-hydroxyvitamin D. Gastroenterology 1982;83:103-8.
    • (1982) Gastroenterology , vol.83 , pp. 103-108
    • Herlong, H.F.1    Recker, R.R.2    Maddrey, W.C.3
  • 110
    • 0028911341 scopus 로고
    • Bone disease in primary biliary cirrhosis: Does ursodeoxycholic acid make a difference?
    • Lindor KD, Janes CH, Crippin JS, Jorgensen RA, Dickson ER. Bone disease in primary biliary cirrhosis: does ursodeoxycholic acid make a difference? Hepatology 1995;21:389-92.
    • (1995) Hepatology , vol.21 , pp. 389-392
    • Lindor, K.D.1    Janes, C.H.2    Crippin, J.S.3    Jorgensen, R.A.4    Dickson, E.R.5
  • 111
    • 0028128248 scopus 로고
    • Parenteral calcitonin for metabolic bone disease associated with primary biliary cirrhosis
    • Camisasca M, Crosignani A, Battezzati PM, et al. Parenteral calcitonin for metabolic bone disease associated with primary biliary cirrhosis. Hepatology 1994;20:633-7.
    • (1994) Hepatology , vol.20 , pp. 633-637
    • Camisasca, M.1    Crosignani, A.2    Battezzati, P.M.3
  • 112
    • 0026783161 scopus 로고
    • Sodium fluoride prevents bone loss in primary biliary cirrhosis
    • Guanabens N, Pares A, del Rio L, et al. Sodium fluoride prevents bone loss in primary biliary cirrhosis. J Hepatol 1992;15:345-9.
    • (1992) J Hepatol , vol.15 , pp. 345-349
    • Guanabens, N.1    Pares, A.2    Del Rio, L.3
  • 114
    • 0028364179 scopus 로고
    • Primary biliary cirrhosis: Survival of a large cohort of symptomatic and asymptomatic patients followed for 24 years
    • Mahl TC, Shockcor W, Boyer JL. Primary biliary cirrhosis: survival of a large cohort of symptomatic and asymptomatic patients followed for 24 years. J Hepatol 1994;20:707-13.
    • (1994) J Hepatol , vol.20 , pp. 707-713
    • Mahl, T.C.1    Shockcor, W.2    Boyer, J.L.3
  • 115
    • 0021946190 scopus 로고
    • Trial of penicillamine in advanced primary biliary cirrhosis
    • Dickson ER, Fleming TR, Wiesner RH, et al. Trial of penicillamine in advanced primary biliary cirrhosis. N Engl J Med 1985;312:1011-5.
    • (1985) N Engl J Med , vol.312 , pp. 1011-1015
    • Dickson, E.R.1    Fleming, T.R.2    Wiesner, R.H.3
  • 116
    • 0029096013 scopus 로고
    • Autoimmune cholangitis: A variant of primary biliary cirrhosis: clinicopathoiogic and serologic correlations in 200 cases
    • Goodman ZD, McNally PR, Davis DR, Ishak KG. Autoimmune cholangitis: a variant of primary biliary cirrhosis: clinicopathoiogic and serologic correlations in 200 cases. Dig Dis Sci 1995;40:1232-42.
    • (1995) Dig Dis Sci , vol.40 , pp. 1232-1242
    • Goodman, Z.D.1    McNally, P.R.2    Davis, D.R.3    Ishak, K.G.4
  • 117
    • 0021839801 scopus 로고
    • Asymptomatic primary biliary cirrhosis: A progress report on long term follow-up and natural history
    • Beswick DR, Klatskin G, Boyer JL. Asymptomatic primary biliary cirrhosis: a progress report on long term follow-up and natural history. Gastroenterology 1985;89:267-71.
    • (1985) Gastroenterology , vol.89 , pp. 267-271
    • Beswick, D.R.1    Klatskin, G.2    Boyer, J.L.3
  • 118
    • 0022406713 scopus 로고
    • Beneficial effect of azathioprine and prediction of prognosis in primary biliary cirrhosis: Final results of an international trial
    • Christensen E, Neuberger J, Crowe J, et al. Beneficial effect of azathioprine and prediction of prognosis in primary biliary cirrhosis: final results of an international trial. Gastroenterology 1985;89:1084-91.
    • (1985) Gastroenterology , vol.89 , pp. 1084-1091
    • Christensen, E.1    Neuberger, J.2    Crowe, J.3
  • 119
    • 0020701724 scopus 로고
    • The prognostic importance of clinical and histologic features in asymptomatic and symptomatic primary biliary cirrhosis
    • Roll J, Boyer JL, Barry D, Klatskin G. The prognostic importance of clinical and histologic features in asymptomatic and symptomatic primary biliary cirrhosis. N Engl J Med 1983;308:1-7.
    • (1983) N Engl J Med , vol.308 , pp. 1-7
    • Roll, J.1    Boyer, J.L.2    Barry, D.3    Klatskin, G.4
  • 120
    • 0026548603 scopus 로고
    • Effects of long-term rifampicin administration in primary biliary cirrhosis
    • Bachs L, Pares A, Elena M, Piera C, Rodes J. Effects of long-term rifampicin administration in primary biliary cirrhosis. Gastroenterology 1992;102:2077-80.
    • (1992) Gastroenterology , vol.102 , pp. 2077-2080
    • Bachs, L.1    Pares, A.2    Elena, M.3    Piera, C.4    Rodes, J.5
  • 121
    • 0028294206 scopus 로고
    • Ursodiol for the long-term treatment of primary biliary cirrhosis
    • Poupon RE, Poupon R, Balkau B, UDCA-PBC Study Group. Ursodiol for the long-term treatment of primary biliary cirrhosis. N Engl J Med 1994;330:1342-7.
    • (1994) N Engl J Med , vol.330 , pp. 1342-1347
    • Poupon, R.E.1    Poupon, R.2    Balkau, B.3
  • 123
    • 0024314830 scopus 로고
    • Variccal bleeding is associated with reduced risk of severe cholestasis in primary biliary cirrhosis
    • Thornton JR, Triger DR, Losowsky MS. Variccal bleeding is associated with reduced risk of severe cholestasis in primary biliary cirrhosis. Q J Med 1989;71:467-71.
    • (1989) Q J Med , vol.71 , pp. 467-471
    • Thornton, J.R.1    Triger, D.R.2    Losowsky, M.S.3
  • 124
    • 0023194324 scopus 로고
    • Portal hypertension in primary biliary cirrhosis: Relationship with histological features
    • Navasa M, Pares A, Bruguera M, Caballeria J, Bosch J, Rodes J. Portal hypertension in primary biliary cirrhosis: relationship with histological features. J Hepatol 1987;5:292-8.
    • (1987) J Hepatol , vol.5 , pp. 292-298
    • Navasa, M.1    Pares, A.2    Bruguera, M.3    Caballeria, J.4    Bosch, J.5    Rodes, J.6
  • 125
    • 0028032950 scopus 로고
    • Effect of distal splenorenal shunt on survival of patients with primary biliary cirrhosis
    • Boyer TD, Kokenes DD, Hertzler G, Kutner MH, Henderson JM. Effect of distal splenorenal shunt on survival of patients with primary biliary cirrhosis. Hepatology 1994;20:1482-6.
    • (1994) Hepatology , vol.20 , pp. 1482-1486
    • Boyer, T.D.1    Kokenes, D.D.2    Hertzler, G.3    Kutner, M.H.4    Henderson, J.M.5
  • 126
    • 0024433049 scopus 로고
    • Extramural cross-validation of the Mayo primary biliary cirrhosis survival model establishes its generalizability
    • Grambsch PM, Dickson ER, Kaplan M, LeSage G, Fleming TR, Langworrhy AL. Extramural cross-validation of the Mayo primary biliary cirrhosis survival model establishes its generalizability. Hepatology 1989; 10:846-50.
    • (1989) Hepatology , vol.10 , pp. 846-850
    • Grambsch, P.M.1    Dickson, E.R.2    Kaplan, M.3    Lesage, G.4    Fleming, T.R.5    Langworrhy, A.L.6
  • 128
    • 0028331716 scopus 로고
    • Ursodeoxycholic acid in the treatment of primary biliary cirrhosis
    • Lindor KD, Dickson ER, Baldus WP, et al. Ursodeoxycholic acid in the treatment of primary biliary cirrhosis. Gastroenterology 1994;106:1284-90.
    • (1994) Gastroenterology , vol.106 , pp. 1284-1290
    • Lindor, K.D.1    Dickson, E.R.2    Baldus, W.P.3
  • 129
    • 0028346255 scopus 로고
    • The Canadian Multicenter Double-blind Randomized Controlled Trial of ursodeoxycholic acid in primary biliary cirrhosis
    • Heathcote EJ, Cauch-Dudek K, Walker V, et al. The Canadian Multicenter Double-blind Randomized Controlled Trial of ursodeoxycholic acid in primary biliary cirrhosis. Hepatology 1994;19:1149-56.
    • (1994) Hepatology , vol.19 , pp. 1149-1156
    • Heathcote, E.J.1    Cauch-Dudek, K.2    Walker, V.3
  • 130
    • 0029127685 scopus 로고
    • A randomized, double-blind, placebo-controlled trial of ursodeoxycholic acid in primary biliary cirrhosis
    • Combes B, Carithers RL Jr, Maddrey WC, et al. A randomized, double-blind, placebo-controlled trial of ursodeoxycholic acid in primary biliary cirrhosis. Hepatology 1995;22:759-66.
    • (1995) Hepatology , vol.22 , pp. 759-766
    • Combes, B.1    Carithers Jr., R.L.2    Maddrey, W.C.3
  • 131
    • 0000940022 scopus 로고
    • Combined analysis of French, American and Canadian randomized controlled trials of ursodeoxycholic acid therapy in primary biliary cirrhosis
    • abstract
    • Heathcote EJ, Lindor KD, Poupon R, et al. Combined analysis of French, American and Canadian randomized controlled trials of ursodeoxycholic acid therapy in primary biliary cirrhosis. Gastroenterology 1995; 108:Suppl:A1082. abstract.
    • (1995) Gastroenterology , vol.108 , Issue.SUPPL
    • Heathcote, E.J.1    Lindor, K.D.2    Poupon, R.3
  • 132
    • 0029041723 scopus 로고
    • Characterisation of patients with a complete biochemical response to ursodeoxycholic acid
    • Jorgensen RA, Dickson ER, Hofmann AF, Rossi SS, Lindor KD. Characterisation of patients With a complete biochemical response to ursodeoxycholic acid. Gut 1995;36:935-8.
    • (1995) Gut , vol.36 , pp. 935-938
    • Jorgensen, R.A.1    Dickson, E.R.2    Hofmann, A.F.3    Rossi, S.S.4    Lindor, K.D.5
  • 133
    • 0025276337 scopus 로고
    • A controlled trial of cyclosporine in the treatment of primary biliary cirrhosis
    • Wiesner RH, Ludwig J, Lindor KD, et al. A controlled trial of cyclosporine in the treatment of primary biliary cirrhosis. N Engl J Med 1990; 322:1419-24.
    • (1990) N Engl J Med , vol.322 , pp. 1419-1424
    • Wiesner, R.H.1    Ludwig, J.2    Lindor, K.D.3
  • 134
    • 0027396144 scopus 로고
    • Cyclosporin A treatment in primary biliary cirrhosis: Results of a long-term placebo controlled trial
    • Lombard M, Portmann B, Neuberger J, et al. Cyclosporin A treatment in primary biliary cirrhosis: results of a long-term placebo controlled trial. Gastroenterology 1993;104:519-26.
    • (1993) Gastroenterology , vol.104 , pp. 519-526
    • Lombard, M.1    Portmann, B.2    Neuberger, J.3
  • 135
    • 0022912599 scopus 로고
    • A prospective trial of colchicinc for primary biliary cirrhosis
    • Kaplan MM, Alling DW, Zimmerman HJ, et al. A prospective trial of colchicinc for primary biliary cirrhosis. N Engl J Med 1986;315:1448-54.
    • (1986) N Engl J Med , vol.315 , pp. 1448-1454
    • Kaplan, M.M.1    Alling, D.W.2    Zimmerman, H.J.3
  • 137
    • 0023262886 scopus 로고
    • A controlled trial of colchicine in primary biliary cirrhosis: Trial design and preliminary report
    • Warnes TW, Smith A, Lee FI, Haboubi NY, Johnson PJ, Hunt L. A controlled trial of colchicine in primary biliary cirrhosis: trial design and preliminary report. J Hepatol 1987;5:1-7.
    • (1987) J Hepatol , vol.5 , pp. 1-7
    • Warnes, T.W.1    Smith, A.2    Lee, F.I.3    Haboubi, N.Y.4    Johnson, P.J.5    Hunt, L.6
  • 138
    • 0026337699 scopus 로고
    • Long-term follow-up of patients with primary biliary cirrhosis on colchicine therapy
    • Zifroni A, Schaffner F. Long-term follow-up of patients with primary biliary cirrhosis on colchicine therapy. Hepatology 1991;14:990-3.
    • (1991) Hepatology , vol.14 , pp. 990-993
    • Zifroni, A.1    Schaffner, F.2
  • 139
    • 0028953372 scopus 로고
    • A placebo-controlled trial of primary biliary cirrhosis treatment with colchicine and ursodeoxycholic acid
    • Vuoristo M, Farkkila M, Karvonen AL, et al. A placebo-controlled trial of primary biliary cirrhosis treatment with colchicine and ursodeoxycholic acid. Gastroenterology 1995;108:1470-8.
    • (1995) Gastroenterology , vol.108 , pp. 1470-1478
    • Vuoristo, M.1    Farkkila, M.2    Karvonen, A.L.3
  • 140
    • 0026690466 scopus 로고
    • Combination therapy with ursodeoxycholic acid and colchicine for primary biliary cirrhosis
    • Shibata J, Fujiyama S, Honda Y, Sato T. Combination therapy with ursodeoxycholic acid and colchicine for primary biliary cirrhosis. J Gastrocnterol Hepatol 1992;7:277-82.
    • (1992) J Gastrocnterol Hepatol , vol.7 , pp. 277-282
    • Shibata, J.1    Fujiyama, S.2    Honda, Y.3    Sato, T.4
  • 141
    • 0026014151 scopus 로고
    • Treatment of primary biliary cirrhosis with low-dose weekly methotrexate
    • Kaplan MM, Knox TA. Treatment of primary biliary cirrhosis with low-dose weekly methotrexate. Gastroenterology 1991;101:1332-8.
    • (1991) Gastroenterology , vol.101 , pp. 1332-1338
    • Kaplan, M.M.1    Knox, T.A.2
  • 142
    • 8244236289 scopus 로고
    • Sustained remission of primary biliary cirrhosis (PBC) with methotrexate (MTX)
    • abstract
    • Kaplan MM. Sustained remission of primary biliary cirrhosis (PBC) with methotrexate (MTX). Gastroenterology 1995;108:Suppl:A1094. abstract.
    • (1995) Gastroenterology , vol.108 , Issue.SUPPL
    • Kaplan, M.M.1
  • 143
    • 4243909947 scopus 로고
    • Double-blind trial of methotrexate (MTX) versus colchicine (COLGH) in primary biliary cirrhosis (PBC)
    • abstract
    • Kaplan M, Schmid C, McKusick A, Provenzale D, Sharma A, Sepe T. Double-blind trial of methotrexate (MTX) versus colchicine (COLGH) in primary biliary cirrhosis (PBC). Hepatology 1993;18:Suppl:176A. abstract.
    • (1993) Hepatology , vol.18 , Issue.SUPPL
    • Kaplan, M.1    Schmid, C.2    McKusick, A.3    Provenzale, D.4    Sharma, A.5    Sepe, T.6
  • 144
    • 4243998829 scopus 로고
    • Methotrexate (MTX) improves histology in primary biliary cirrhosis (PBC)
    • abstract
    • Kaplan MM, Dickstein G, Schmid C. Methotrexate (MTX) improves histology in primary biliary cirrhosis (PBC). Hepatology 1994;20:Suppl: 152A. abstract.
    • (1994) Hepatology , vol.20 , Issue.SUPPL
    • Kaplan, M.M.1    Dickstein, G.2    Schmid, C.3
  • 145
    • 0029145990 scopus 로고
    • Synthesis of interleukin-1 beta in primary biliary cirrhosis: Relationship to treatment with methotrexate or colchicine and disease progression
    • Miller LC, Sharma A, McKusick AF, Tassoni JP, Dinarello CA, Kaplan MM. Synthesis of interleukin-1 beta in primary biliary cirrhosis: relationship to treatment with methotrexate or colchicine and disease progression. Hepatology 1995;22:518-24.
    • (1995) Hepatology , vol.22 , pp. 518-524
    • Miller, L.C.1    Sharma, A.2    McKusick, A.F.3    Tassoni, J.P.4    Dinarello, C.A.5    Kaplan, M.M.6
  • 146
    • 0002644425 scopus 로고
    • The therapeutic effects, of ursodiol and methotrexate are additive and well tolerated in primary biliary cirrhosis (PBC)
    • abstract
    • Kaplan MM. The therapeutic effects, of ursodiol and methotrexate are additive and well tolerated in primary biliary cirrhosis (PBC). Hepatology 1992;16:Suppl:92A. abstract.
    • (1992) Hepatology , vol.16 , Issue.SUPPL
    • Kaplan, M.M.1
  • 147
    • 0027190525 scopus 로고
    • Positive responses to methotrexate and ursodeoxycholic acid in patients with primary biliary cirrhosis responding insufficiently to ursodeoxycholic acid alone
    • Buscher HP, Zietzschmann Y, Gerok W. Positive responses to methotrexate and ursodeoxycholic acid in patients with primary biliary cirrhosis responding insufficiently to ursodeoxycholic acid alone. J Hepatol 1993; 18:9-14.
    • (1993) J Hepatol , vol.18 , pp. 9-14
    • Buscher, H.P.1    Zietzschmann, Y.2    Gerok, W.3
  • 148
    • 0029122841 scopus 로고
    • The combination of ursodeoxycholic acid and methotrexate for patients with primary biliary cirrhosis: The results of a pilot study
    • Lindor KD, Dickson ER, Jorgensen RA, et al. The combination of ursodeoxycholic acid and methotrexate for patients with primary biliary cirrhosis: the results of a pilot study. Hepatology 1995;22:1158-62.
    • (1995) Hepatology , vol.22 , pp. 1158-1162
    • Lindor, K.D.1    Dickson, E.R.2    Jorgensen, R.A.3
  • 149
    • 0028361688 scopus 로고
    • Interstitial pneumonitis after low-dose methotrexate therapy in primary biliary cirrhosis
    • Sharma A, Provenzale D, McKusick A, Kaplan MM. Interstitial pneumonitis after low-dose methotrexate therapy in primary biliary cirrhosis. Gastroenterology 1994;107:266-70.
    • (1994) Gastroenterology , vol.107 , pp. 266-270
    • Sharma, A.1    Provenzale, D.2    McKusick, A.3    Kaplan, M.M.4
  • 150
    • 0024475313 scopus 로고
    • Efficacy of liver transplantation in patients with primary biliary cirrhosis
    • Markus BH, Dickson ER, Grambsch PM, et al. Efficacy of liver transplantation in patients with primary biliary cirrhosis. N Engl J Med 1989; 320:1709-13.
    • (1989) N Engl J Med , vol.320 , pp. 1709-1713
    • Markus, B.H.1    Dickson, E.R.2    Grambsch, P.M.3
  • 151
    • 0028266212 scopus 로고
    • Is there recurrence of primary biliary cirrhosis after liver transplantation? A clinicopathologic study in long-term survivors
    • Gouw AS, Haagsma EB, Manns M, Klompmaker IJ, Slooff MJ, Gerber MA. Is there recurrence of primary biliary cirrhosis after liver transplantation? A clinicopathologic study in long-term survivors. J Hepatol 1994; 20:500-7.
    • (1994) J Hepatol , vol.20 , pp. 500-507
    • Gouw, A.S.1    Haagsma, E.B.2    Manns, M.3    Klompmaker, I.J.4    Slooff, M.J.5    Gerber, M.A.6
  • 152
    • 0027433101 scopus 로고
    • Histological evidence for recurrence of primary biliary cirrhosis after liver transplantation
    • Balan V, Bans KP, Porayko MK, Krom RA, Ludwig J, Wiesner RH. Histological evidence for recurrence of primary biliary cirrhosis after liver transplantation. Hepatology 1993;18:1392-8.
    • (1993) Hepatology , vol.18 , pp. 1392-1398
    • Balan, V.1    Bans, K.P.2    Porayko, M.K.3    Krom, R.A.4    Ludwig, J.5    Wiesner, R.H.6
  • 153
    • 0028351175 scopus 로고
    • Primary biliary cirrhosis - A first step in prolonging survival
    • Kaplan MM. Primary biliary cirrhosis - a first step in prolonging survival. N Engl J Med 1994;330:1386-7.
    • (1994) N Engl J Med , vol.330 , pp. 1386-1387
    • Kaplan, M.M.1


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