Microtubule depolymerization in Uromyces appendiculatus by three new antineoplastic drugs: Combretastatin A-4, dolastatin 10 and halichondrin B

Mycological Research

Volumn 102, Issue 3, 1998, Pages 378-382

  Roberson, Robert W ^a   Tucker, Bruce ^a   Pettit, George R ^a  

^a ARIZONA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

UROMYCES APPENDICULATUS;

EID: 0031791040     PISSN: 09537562     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0953756297004930     Document Type: Article

References (17)

1. Bai, R., Paull K. D., Herald, C. L., Malspeis, L., Pettit, G. R. & Hamel, E. (1991). Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of the tubulin-based mechanism of action by analysis of differential cytotoxicity data. Journal of Biological Chemistry 266, 15882-15889.
2. Bai, R., Pettit, G. R. & Hamel, E. (1990). Binding of Dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites. Journal of Biological Chemistry 265, 17141-17149.
3. Davidse, L. C. & Flach, W. (1977). Differential binding of methyl benzimidazol-2-yl carbamate to fungal tubulin as a mechanism of resistance to this antimitotic agent in mutant strains of Aspergillus nidulans. Journal of Cell Biology 72, 174-192.
4. Dustin, P. (1984). Microtubules. Springer-Verlag: New York.
5. 2O and taxol. European Journal of Cell Biology 41, 290-297.
6. Hoch, H. C. & Staples, R. C. (1985). The microtubule cytoskeleton in hyphae of Uromyces phaseoli germlings: its relationship to the region of nucleation and to the F-actin cytoskeleton. Protoplasma 124, 112-122.
7. Hoch, H. C., Tucker, B. E. & Staples, R. C. (1987). An intact microtubule cytoskeleton is necessary for mediation of the signal for cell differentiation in Uromyces. European Journal of Cell Biology 45, 209-218.
8. Kwon, Y. H., Hoch, H. C. & Staples, R. C. (1991). Cytoskeletal organization in Uromyces uredospore germling apices during apressorium formation. Protoplasma 165, 37-50.
9. Lowry, D. & Roberson, R. W. (1997). The microtubule cytoskeleton during zoospore formation in Allomyces macrogynus. Protoplasma 196, 45-54.
10. Lin, C. M., Ho, H. H., Pettit, G. R. & Hamel, E. (1989). Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin. Biochemistry 28, 6984-6991.
11. Pettit, G. R., Kizu, H., Schmidt, J. M., Baczynskyj, L., Tomer, K. B. & Bontems, R. J. (1987). The isolation and structure of a remarkable marine animal antineoplastic constituent: dolastatin 10. Journal of the American Chemical Society 109, 6883-6885.
12. Pettit, G. R., Singh, S. B., Hamel, E., Lin, C. M., Alberts, D. S. & García-Kendall, D. (1989 a). Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4. Experientia 45, 209-211.
13. Pettit, G. R., Singh, S. B., Hogan, F., Lloyd-Williams, P., Herald, D. L., Burdett, D. D. & Clewlow, P. J. (1989 b). The absolute configuration and synthesis of (-)-Dolastatin 10. Journal of the American Chemical Society 111, 5463-5465.
14. Roberson, R. W. & Fuller, M. S. (1988). Ultrastructural aspects of the hyphal tip of Sclerotium rolfsii preserved by freeze substitution. Protoplasma 146, 143-149.
15. Roberson, R. W. & Vargas, M. M. (1994). The tubulin cytoskeleton and its sites of nucleation in Allomyces macrogynus. Protoplasma 182, 19-31.
16. Śantavy, F. (1979). Colchicine alkaloids and related substances - their chemistry and biology. Acta Universitatis Palackianae Olomucensis 90, 15-44.
17. Srijayanthi, S., Vargas, M. M. & Roberson, R. W. (1996). Functional, organizational, and biochemical analysis of actin in the hyphal tip cells of Allomyces macrogynus. Mycologia 88, 57-70.