A new anti-tubulin agent containing the benzo[b]thiophene ring system

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 8, 1999, Pages 1081-1086

  Pinney, Kevin G ^a   Bounds, A Dawn ^a   Dingeman, Koren M ^a   Mocharla, Vani P ^a   Pettit, George R ^b   Bai, Ruoli ^c   Hamel, Ernest ^c  

^a BAYLOR UNIVERSITY   (United States)

^b ARIZONA STATE UNIVERSITY   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (4' METHOXYPHENYL) 3 (3',4',5' TRIMETHOXYBENZOYL) 6 METHOXYBENZO[B]THIOPHENE; BENZOTHIOPHENE DERIVATIVE; TUBULIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CYCLIZATION; CYTOTOXICITY; DRUG STRUCTURE; MITOSIS INDEX; PROTEIN BINDING; PROTEIN POLYMERIZATION; X RAY CRYSTALLOGRAPHY;

DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROLYSIS; THIOPHENES; TIME FACTORS; TUBULIN; TUBULIN MODULATORS; TUMOR CELLS, CULTURED;

EID: 0033583499     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00143-2     Document Type: Article

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