Activin signal transduction pathways

Trends in Endocrinology and Metabolism

Volumn 11, Issue 8, 2000, Pages 309-314

  Pangas, Stephanie A ^a   Woodruff, Teresa K ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN; BONE MORPHOGENETIC PROTEIN; INHIBIN; LIGAND; PROTEIN TYROSINE KINASE INHIBITOR; RECEPTOR SUBUNIT; TRANSFORMING GROWTH FACTOR BETA;

CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; ENDOCRINE CELL; LIGAND BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; REVIEW; SIGNAL TRANSDUCTION;

EID: 0033807054     PISSN: 10432760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1043-2760(00)00294-0     Document Type: Review

References (52)

1. Activins and the receptor serine kinase superfamily
2. Identification of a new member of transforming growth factor-beta superfamily in Drosophila: The first invertebrate activin gene
3. TGF-beta family signal transduction in Drosophila development: From Mad to Smads
4. Genetic screens to identify elements of the decapentaplegic signaling pathway in Drosophila melanogaster
5. Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster
6. The C. elegans sma-2, sma-3, and sma-4 genes define a novel conserved family of TGF-beta pathway components
7. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
8. Resistance to transforming growth factor beta and activin due to reduced receptor expression in human breast tumor cell lines
9. Regulation of differentiation by TGF-β
10. Regulation of cellular and system function by activin
11. Chemical and biological characterization of the inhibin family of protein hormones
12. Transgenic models to study the roles of inhibin and activins in reproduction, oncogenesis, and development
13. Genes coding for mouse activin beta C and beta E are closely linked and exhibit a liver-specific expression pattern in adult tissues
14. Aspects of current and future inhibin research
15. Activin receptors: Cellular signaling by receptor serine kinases
16. Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors
17. Molecular and functional characterization of activin receptors
18. Activin receptors and cellular signaling by the receptor serine kinase family
19. Specific activation of Smad1 signaling pathways by BMP7 type I receptor, ALK2
20. Controlling TGF-beta signaling
21. Activin A-induced HepG2 liver cell apoptosis: Involvement of activin receptors and smad proteins
22. TGF beta-related pathways. Roles in Caenorhabditis elegans development
23. Roles of pathway-specific and inhibitory Smads in activin receptor signaling
24. Opposing BMP and EGF Signaling pathways converge on the TGF-beta family mediator Smad1
25. Smad2 transduces common signals for receptor serine-threonine kinases
26. Role of ras and mapks in TGFbeta signaling
27. Physical and functional interaction of Smads and p300/CBP
28. E1A inhibits transforming growth factor-beta signaling through binding to Smad proteins
29. Positive and negative modulation of vitamin D receptor function by transforming growth factor-beta signaling through smad proteins
30. Convergence of transforming growth factor-beta and vitamin D signaling pathways on SMAD transcriptional coactivators
31. Smad proteins physically interact with calmodulin
32. Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12
33. Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12
34. The p21 (RAS) farnesyltransferase alpha subunit in TGF-beta and activin signaling
35. Identification of STRAP, a novel WD domain protein in transforming growth factor-beta signaling
36. Structural basis of Smad2 recognition by the Smad anchor for receptor activation
37. Inhibin, activin and female reproductive axis
38. Chondrogenesis in chick limb bud mesodermal cells: Reciprocal modulation by activin and inhibin
39. 3H] thymidine uptake by rat thymocytes and 3T3 cells in vitro
40. Left/right patterning signals and the independent regulation of different aspects of situs in the chick embryo
41. Control of digit formation by activin signaling
42. Activin as a nerve cell survival molecule
43. Mesoderm-inducing factors in early vertebrate development
44. Follistatin and activin: A potential intrinsic regulatory system within diverse tissues
45. Antivin, a novel and divergent member of the TGF-beta superfamily, negatively regulates mesoderm induction
46. Regulation of inhibin synthesis in the rat ovary
47. Betaglycan binds inhibin and can mediate functional antagonism of activin signaling
48. TGF beta signal transduction
49. Hope, hypothesis and the inhibin receptor. Does specific inhibin binding suggest there is a specific inhibin receptor?
50. Identification of an inhibin receptor in gonadal tumors from inhibin alpha-subunit knockout mice
51. Localization of inhibin and activin binding sites in the testis during development by in situ ligand binding
52. Identification of high affinity binding sites for inhibin on ovine pituitary cells in culture