Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells

Journal of Biological Chemistry

Volumn 271, Issue 38, 1996, Pages 23588-23593

  Stein, Elke ^a   Cerretti, Douglas Pat ^b   Daniel, Thomas O ^a,c  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b AMGEN INC   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; HYBRID PROTEIN; LIGAND; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ARTICLE; CELL MIGRATION; DNA DETERMINATION; ENDOTHELIUM CELL; LIGAND BINDING; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; VASCULAR ENDOTHELIUM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; DNA-BINDING PROTEINS; ENDOTHELIUM, VASCULAR; EPHRIN-B1; ETS-DOMAIN PROTEIN ELK-1; GRB10 ADAPTOR PROTEIN; GRB2 ADAPTOR PROTEIN; HUMANS; KIDNEY; LIGANDS; MICE; PHOSPHORYLATION; PROTEIN BINDING; PROTEINS; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

ANIMALIA; CAENORHABDITIS ELEGANS; MURINAE; TRITICUM AESTIVUM; UNIDENTIFIED BACULOVIRUS;

EID: 0029813872     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.38.23588     Document Type: Article

References (35)

1. Bergemann, A. D., Cheng, H.-J., Brambilla, R., Klein, R., and Flanagan, J. G. (1995) Mol. Cell. Biol. 15, 4921-4929
2. Drescher, U., Kremoser, C., Handwerker, C., Loschinger, J., Noda, M., and Bonhoeffer, F. (1995) Cell 82, 359-370
3. Pandey, A., Shao, H., Marks, R. M., Polverini, P. J., and Dixit, V. M. (1995) Science 268, 567-569
4. Winslow, J. W., Moran, P., Valverde, J., Shih, A., Yuan, J. Q., Wong, S. C., Tsai, S. P., Goddard, A., Henzel, W. J., Hefti, F., Beck, K. D., and Caras, I. W. (1995) Neuron 14, 973-981
5. Henkemeyer, M., Marengere, L. E. M., McGlade, J., Olivier, J. P., Conlon, R. A., Holmyard, D. P., Letwin, K., and Pawson, T. (1994) Oncogene 9, 1001-1014
6. Pandey, A., Lindberg, R. A., and Dixit, V. M. (1995) Curr. Biol. 5, 986-989
7. Tang, X. X., Biegel, J. A., Nycum, L. M., Yoshioka, A., Brodeur, G. M., Pleasure, D. E., and Ikegaki, N. (1995) Genomics 29, 426-437
8. Davis, S., Gale, N. W., Aldrich, T. H., Maisonpierre, P. C., Lhotak, V., Pawson, T., Goldfarb, M., and Yancopoulos, G. D. (1994) Science 226, 816-819
9. Kozlosky, C. J., Maraskovsky, E., McGrew, J. T., VandenBos, T., Teepe, M., Lyman, S. D., Srinivasan, S., Fletcher, F. A., Gayle, R. B., III, Cerretti, D. P., and Beckmann, M. P. (1995) Oncogene 10, 299-306
10. Beckmann, M. P., Cerretti, D. P., Baum, P., Vanden Bos, T., James, L., Farrah, T., Kozlosky, C., Hollingsworth, T., Shilling, H., Maraskovsky, E., Fletcher, F. A., Lhotak, V., Pawson, T., and Lyman, S. D. (1994) EMBO J. 13, 3757-3762
11. Cerretti, D. P., VandenBos, T., Nelson, N., Kozlosky, C. J., Reddy, P., Maraskovsky, E., Park, L. S., Lyman, S. D., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., and Fletcher, F. A. (1996) Mol. Immunol. 32, 1197-1205
12. Brambilla, R., Schnapp, A., Casagranda, F., Labrador, J. P., Bergemann, A. D., Flanagan, J. G., Pasquale, E. B., and Klein, R. (1995) EMBO J. 14, 3116-3126
13. Haun, R. S., Serventi, I. M., and Moss, J. (1992) Biotechniques 13, 515-518
14. Gruenwald, S., and Singh, S. (1995) in PharMingen Research Products Catalog, San Diego, CA
15. Vojtek, A. B., Hollenberg, S. M., and Cooper, J. A. (1993) Cell 74, 205-214
16. Ho, S. N., Hunt, H. D., Horton, R. M., Pullen, J. K., and Pease, L. R. (1989) Gene (Amst.) 77, 51-59
17. Wojta, J., Hoover, R. L., and Daniel, T. O. (1989) J. Biol. Chem. 264, 2846-2852
18. Rose, M. S., Winston, F., and Hieter, P. (1990) Methods in Yeast Genetics. A Laboratory Course Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
19. Hill, J., Donald, K. A., and Griffins, D. E. (1991) Nucleic Acids Res. 19, 5791
20. Schiestl, R. H., and Giest, R. D. (1989) Curr. Genet. 16, 339-346
21. Bio-Rad Laboratories, Inc. (1994) E. coli Pulser Transformation Apparatus, Hercules, CA
22. Ward, A. C. (1990) Nucleic Acids Res. 18, 5319
23. Altschul, S. F., Gish, W., Miller, W., Myers, E. W., and Lipman, D. J. (1990) J. Mol. Biol. 215, 403-410
24. Gruenwald, S., and Singh, S. (1995) Baculovirus Expression Vector System: Procedure and Methods Manual, Pharmingen, San Diego, CA
25. Kumjian, D. A., Wahl, M. I., Rhee, S. G., and Daniel, T. O. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 8232-8236
26. Carpenter, M. K., Shilling, H., VandenBos, T., Beckmann, M. P., Cerretti, D. P., Kott, J. N., Westrum, L. E., Davison, B. L., and Fletcher, F. A. (1995) J. Neurosci. Res. 42, 199-206
27. Ooi, J., Yajnik, V., Immanuel, D., Gordon, M., Moskow, J. J., Buchberg, A. M., and Margolis, B. (1995) Oncogene 10, 1621-1630
28. Songyang, Z., Shoelson, S. E., Chaudhuri, M., Gish, G., Pawson, T., Haser, W. G., King, F., Roberts, T., Ratnofsky, S., Lechleider, R. J., Neel, B. G., Birge, R. B., Fajardo, J. E., Chou, M. M., Hanafusa, H., Schaffhausen, B., and Cantley, L. C. (1993) Cell 72, 767-778
29. Pandey, A., Lazar, D. F., Saltiel, A. R., and Dixit, V. M. (1994) J. Biol. Chem. 269, 30154-30157
30. Pandey, A., Duan, H., and Dixit, V. M. (1995) J. Biol. Chem. 270, 19201-19204
31. Schlessinger, J. (1996) Curr. Opin. Genet. Dev. 4, 25-30
32. Marshall, C. J. (1995) Cell 80, 179-185
33. Buday, L., and Downward, J. (1993) Cell 73, 611-620
34. Obermeir, A., Bradshaw, R. A., Seedorf, K., Choidas, A., Schlessinger, J., and Ullrich, A. (1994) EMBO J. 13, 1585-1590
35. Pandey, A., Duan, H., Di Fiore, P. P., and Dixit, V. M. (1995) J. Biol. Chem. 270, 21461-21463