Inverse agonism and neutral antagonism at a constitutively active alpha-1a adrenoceptor

British Journal of Pharmacology

Volumn 131, Issue 3, 2000, Pages 546-552

  Zhu, J ^a   Taniguchi, T ^a   Takauji, R ^a   Suzuki, F ^a   Tanaka, T ^a   Muramatsu, I ^a  

^a UNIVERSITY OF FUKUI   (Japan)

Author keywords

Alpha 1 adrenoceptor; Constitutive activity; Inverse agonist; Mutant; Neutral antagonist

Indexed keywords

ALANINE; ALPHA 1A ADRENERGIC RECEPTOR; G PROTEIN COUPLED RECEPTOR; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); INOSITOL 1,4,5 TRISPHOSPHATE; MUTANT PROTEIN; PRAZOSIN; SILODOSIN;

ALPHA ADRENERGIC STIMULATION; ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG BINDING SITE; DRUG MECHANISM; DRUG RECEPTOR BINDING; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DENSITY;

EID: 0033776642     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703584     Document Type: Article

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