메뉴 건너뛰기




Volumn 50, Issue 6, 1996, Pages 1479-1486

Inverse agonist-induced up-regulation of the human β2-adrenoceptor in transfected neuroblastoma X glioma hybrid cells

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ALPRENOLOL; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BETAXOLOL; COMPLEMENTARY DNA; CYCLOHEXIMIDE; DIHYDROALPRENOLOL; EPHEDRINE; GUANINE NUCLEOTIDE BINDING PROTEIN; ILOPROST; ISOPRENALINE; MESSENGER RNA; SOTALOL;

EID: 0030473469     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (73)

References (38)
  • 2
    • 0027297275 scopus 로고
    • Constitutive activity of receptors coupled to guanine-nucleotide regulatory proteins
    • Lefkowitz, R. J., S. Cotecchia, P. Samama, and T. Costa. Constitutive activity of receptors coupled to guanine-nucleotide regulatory proteins. Trends Pharmacol. Sci. 14:303-307 (1993).
    • (1993) Trends Pharmacol. Sci. , vol.14 , pp. 303-307
    • Lefkowitz, R.J.1    Cotecchia, S.2    Samama, P.3    Costa, T.4
  • 4
    • 0028861330 scopus 로고
    • Inverse agonism: Pharmacological curiosity or potential therapeutic strategy?
    • Milligan, G., R. A. Bond, and M. Lee. Inverse agonism: pharmacological curiosity or potential therapeutic strategy? Trends Pharmacol. Sci. 16: 10-13 (1995).
    • (1995) Trends Pharmacol. Sci. , vol.16 , pp. 10-13
    • Milligan, G.1    Bond, R.A.2    Lee, M.3
  • 5
    • 0029958767 scopus 로고    scopus 로고
    • Analysis of inverse agonism at the δ opioid receptor after expression in rat 1 fibroblasts
    • Mullaney, I., I. C. Carr, and G. Milligan. Analysis of inverse agonism at the δ opioid receptor after expression in rat 1 fibroblasts Biochem. J. 315:227-234 (1996).
    • (1996) Biochem. J. , vol.315 , pp. 227-234
    • Mullaney, I.1    Carr, I.C.2    Milligan, G.3
  • 6
    • 0027959963 scopus 로고
    • High agonist-independent activity is a distinguishing feature of the dopamine D1B receptor subtype
    • Tiberi, M., and M. G. Caron. High agonist-independent activity is a distinguishing feature of the dopamine D1B receptor subtype. J. Biol. Chem. 269:27925-27931 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 27925-27931
    • Tiberi, M.1    Caron, M.G.2
  • 7
    • 0001169515 scopus 로고
    • Antagonists with negative intrinsic activity at delta-opioid receptors coupled to GTP-binding proteins
    • Costa, T., and A. Herz. Antagonists with negative intrinsic activity at delta-opioid receptors coupled to GTP-binding proteins. Proc. Natl. Acad. Sci. USA 86:7321-7325 (1989).
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 7321-7325
    • Costa, T.1    Herz, A.2
  • 9
    • 0028119463 scopus 로고
    • 2 adrenoceptor: Evidence for empty receptor stimulation of the adenylate cyclase cascade
    • 2 adrenoceptor: evidence for empty receptor stimulation of the adenylate cyclase cascade. Biochem. J. 303:803-808 (1994).
    • (1994) Biochem. J. , vol.303 , pp. 803-808
    • Adie, E.J.1    Milligan, G.2
  • 12
    • 0000046089 scopus 로고
    • A human beta-actin expression vector system directs high-level accumulation of antisense transcripts
    • Gunning, P., J. Leavitt, G. Muscat, S. Y. Ng, and L. Kedes. A human beta-actin expression vector system directs high-level accumulation of antisense transcripts. Proc. Natl. Acad. Sci. USA 84:4831-4835 (1987).
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 4831-4835
    • Gunning, P.1    Leavitt, J.2    Muscat, G.3    Ng, S.Y.4    Kedes, L.5
  • 14
    • 0023655416 scopus 로고
    • Fetal-calf serum stimulates a pertussis-toxin-sensitive highaffinity GTPase activity in rat glioma C6 BU1 cells
    • Milligan, G. Fetal-calf serum stimulates a pertussis-toxin-sensitive highaffinity GTPase activity in rat glioma C6 BU1 cells. Biochem. J. 245:501-505 (1987).
    • (1987) Biochem. J. , vol.245 , pp. 501-505
    • Milligan, G.1
  • 15
    • 0023237925 scopus 로고
    • Development of opiate receptors and GTP-binding regulatory proteins in neonatal rat brain
    • Milligan, G., R. A. Streaty, P. Gierschik, A. M. Spiegel, and W. A. Klee. Development of opiate receptors and GTP-binding regulatory proteins in neonatal rat brain. J. Biol. Chem. 262:8626-8630 (1987).
    • (1987) J. Biol. Chem. , vol.262 , pp. 8626-8630
    • Milligan, G.1    Streaty, R.A.2    Gierschik, P.3    Spiegel, A.M.4    Klee, W.A.5
  • 16
    • 0025793604 scopus 로고
    • Assay of adenylyl cyclase catalytic activity
    • Johnson, R. A., and Y. Salomon. Assay of adenylyl cyclase catalytic activity. Methods Enzymol. 195:3-21 (1991).
    • (1991) Methods Enzymol. , vol.195 , pp. 3-21
    • Johnson, R.A.1    Salomon, Y.2
  • 17
    • 0028673020 scopus 로고
    • Determination of adenylyl-cyclase catalytic activity using single and double column procedures
    • Johnson, R. A., R. Alvarez, and Y. Salomon. Determination of adenylyl-cyclase catalytic activity using single and double column procedures. Methods Enzymol. 238:31-56 (1994).
    • (1994) Methods Enzymol. , vol.238 , pp. 31-56
    • Johnson, R.A.1    Alvarez, R.2    Salomon, Y.3
  • 19
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159 (1987).
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 21
    • 0028925917 scopus 로고
    • 11 alpha (pertussis toxin-insensitive) G-proteins in alpha-T3-1 gonadotroph cells reflects increased G-protein turnover but not alterations in messenger-RNA levels
    • 11 alpha (pertussis toxin-insensitive) G-proteins in alpha-T3-1 gonadotroph cells reflects increased G-protein turnover but not alterations in messenger-RNA levels. Proc. Natl. Acad. Sci. USA 92:1886-1890 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1886-1890
    • Shah, B.H.1    MacEwan, D.J.2    Milligan, G.3
  • 25
    • 0025812324 scopus 로고
    • Model systems for the study of seven-transmembrane-segment receptors
    • Dohlman, H. G., J. Thorner, M. G. Caron, and R. J. Lefkowitz. Model systems for the study of seven-transmembrane-segment receptors. Annu. Rev. Biochem. 60:653-688 (1991).
    • (1991) Annu. Rev. Biochem. , vol.60 , pp. 653-688
    • Dohlman, H.G.1    Thorner, J.2    Caron, M.G.3    Lefkowitz, R.J.4
  • 26
    • 0027375964 scopus 로고
    • Molecular mechanisms of membrane receptor desensitization
    • Lohse, M. J. Molecular mechanisms of membrane receptor desensitization. Biochim. Biophys. Acta 1179:171-188 (1993).
    • (1993) Biochim. Biophys. Acta , vol.1179 , pp. 171-188
    • Lohse, M.J.1
  • 27
    • 0028180127 scopus 로고
    • Constitutively active 5-hydroxytryptamine 2C (5HT2C) receptors reveal novel inverse agonist activity of receptor ligands
    • Barker, E. L., R. S. Westphal, D. Schmidt, and E. Sanders-Bush. Constitutively active 5-hydroxytryptamine 2C (5HT2C) receptors reveal novel inverse agonist activity of receptor ligands. J. Biol. Chem. 269:11687-11690 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 11687-11690
    • Barker, E.L.1    Westphal, R.S.2    Schmidt, D.3    Sanders-Bush, E.4
  • 28
    • 0029045445 scopus 로고
    • Serotonergic antagonists differentially inhibit spontaneous activity and decrease ligand binding capacity of the rat 5-hydroxytryptamine type 2C receptor in Sf9 cells
    • Labrecque, J., A. Fargin, M. Bouvier, P. Chidiac, and M. Dennis. Serotonergic antagonists differentially inhibit spontaneous activity and decrease ligand binding capacity of the rat 5-hydroxytryptamine type 2C receptor in Sf9 cells. Mol. Pharmacol. 48:150-159 (1995).
    • (1995) Mol. Pharmacol. , vol.48 , pp. 150-159
    • Labrecque, J.1    Fargin, A.2    Bouvier, M.3    Chidiac, P.4    Dennis, M.5
  • 30
    • 0028039928 scopus 로고
    • Quantitative stoichiometry of the proteins of the stimulatory arm of the adenylyl cyclase cascade in neuroblastoma-X-glioma hybrid, NG108-15 cells
    • Kim, G. D., E. J. Adie, and G. Milligan. Quantitative stoichiometry of the proteins of the stimulatory arm of the adenylyl cyclase cascade in neuroblastoma-X-glioma hybrid, NG108-15 cells. Eur. J. Biochem. 219:135-143 (1994).
    • (1994) Eur. J. Biochem. , vol.219 , pp. 135-143
    • Kim, G.D.1    Adie, E.J.2    Milligan, G.3
  • 32
    • 0027984645 scopus 로고
    • Receptor availability defines the extent of agonist-mediated G-protein down-regulation in neuroblastoma X glioma hybrid cells transfected to express the beta-2-adrenoceptor
    • Kim, G. D., and G. Milligan. Receptor availability defines the extent of agonist-mediated G-protein down-regulation in neuroblastoma X glioma hybrid cells transfected to express the beta-2-adrenoceptor. FEBS Lett. 355:166-170 (1994).
    • (1994) FEBS Lett. , vol.355 , pp. 166-170
    • Kim, G.D.1    Milligan, G.2
  • 33
    • 0024040764 scopus 로고
    • Down-regulation of beta-adrenergic receptors: Agonist-induced reduction in receptor messenger-RNA levels
    • Hadcock, J. R., and C. C. Malbon. Down-regulation of beta-adrenergic receptors: agonist-induced reduction in receptor messenger-RNA levels. Proc. Natl. Acad. Sci. USA 85:5021-5025 (1988).
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 5021-5025
    • Hadcock, J.R.1    Malbon, C.C.2
  • 34
    • 0012878853 scopus 로고
    • Regulation of beta-adrenergic receptors by permissive hormones: Glucocorticoids increase steady-state levels of receptor messenger-RNA
    • Hadcock, J. R., and C. C. Malbon. Regulation of beta-adrenergic receptors by permissive hormones: glucocorticoids increase steady-state levels of receptor messenger-RNA. Proc. Natl. Acad. Sci. USA 85:8415-8419 (1988).
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8415-8419
    • Hadcock, J.R.1    Malbon, C.C.2
  • 35
    • 0024341172 scopus 로고
    • Agonist-induced destabilization of beta-adrenergic-receptor messenger-RNA attenuation of glucocorticoid-induced up-regulation of beta-adrenergic receptors
    • Hadcock, J. R., H. Y. Wang, and C. C. Malbon. Agonist-induced destabilization of beta-adrenergic-receptor messenger-RNA attenuation of glucocorticoid-induced up-regulation of beta-adrenergic receptors. J. Biol. Chem. 264:19928-19933 (1989).
    • (1989) J. Biol. Chem. , vol.264 , pp. 19928-19933
    • Hadcock, J.R.1    Wang, H.Y.2    Malbon, C.C.3
  • 36
    • 0027055590 scopus 로고
    • beta-Adrenergic agonists that down-regulate receptor messenger-RNA up-regulate a M(R) 35,000 protein(s) that selectively binds to beta-adrenergic-receptor messenger-RNAs
    • Port, J. D., L. Y. Huang, and C. C. Malbon. beta-Adrenergic agonists that down-regulate receptor messenger-RNA up-regulate a M(R) 35,000 protein(s) that selectively binds to beta-adrenergic-receptor messenger-RNAs. J. Biol. Chem. 267:24103-24108 (1992).
    • (1992) J. Biol. Chem. , vol.267 , pp. 24103-24108
    • Port, J.D.1    Huang, L.Y.2    Malbon, C.C.3
  • 37
    • 0025797371 scopus 로고
    • Regulation of receptor expression by agonists: Transcriptional and posttranscriptional controls
    • Hadcock, J. R., and C. C. Malbon. Regulation of receptor expression by agonists: transcriptional and posttranscriptional controls. Trends Neurosci. 14:242-247 (1991).
    • (1991) Trends Neurosci. , vol.14 , pp. 242-247
    • Hadcock, J.R.1    Malbon, C.C.2
  • 38
    • 0026513232 scopus 로고
    • From ligand binding to gene expression: New insights into the regulation of G protein coupled receptors
    • Collins, S, M. G. Caron, and R. J. Lefkowitz. From ligand binding to gene expression: new insights into the regulation of G protein coupled receptors. Trends Biochem. Sci. 17:37-39 (1992).
    • (1992) Trends Biochem. Sci. , vol.17 , pp. 37-39
    • Collins, S.1    Caron, M.G.2    Lefkowitz, R.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.