Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 9, 1998, Pages 5372-5377

  Beck, Laurent ^a   Karaplis, Andrew C ^b   Amizuka, Norio ^c   Hewson, A Stacy ^a   Ozawa, Hidehiro ^c   Tenenhouse, Harriet S ^a,d  

^a RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c NIIGATA UNIVERSITY   (Japan)

^d MONTREAL CHILDREN S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

PARATHYROID HORMONE; PHOSPHATASE;

ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL DISORDER; BRUSH BORDER; GENE DISRUPTION; HYPERCALCEMIA; HYPERCALCIURIA; HYPOPHOSPHATEMIA; KIDNEY PROXIMAL TUBULE; MOUSE; MUTAGENESIS; NONHUMAN; PARATHYROID HORMONE BLOOD LEVEL; PHENOTYPE; PHOSPHATE METABOLISM; PHOSPHATE TRANSPORT; PRIORITY JOURNAL; SKELETON MALFORMATION; SODIUM TRANSPORT; VITAMIN D RESISTANT RICKETS;

ANIMALS; BIOLOGICAL TRANSPORT; BODY WEIGHT; BONE AND BONES; CALCITRIOL; CALCIUM; CARRIER PROTEINS; FEMALE; GENE EXPRESSION; HETEROZYGOTE; KIDNEY; MALE; MICE; MICE, KNOCKOUT; MICROVILLI; PHOSPHATES; RNA, MESSENGER; SODIUM; SODIUM-PHOSPHATE COTRANSPORTER PROTEINS; SODIUM-PHOSPHATE COTRANSPORTER PROTEINS, TYPE I; SODIUM-PHOSPHATE COTRANSPORTER PROTEINS, TYPE III; SYMPORTERS;

ANIMALIA; RODENTIA;

EID: 0032574725     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.9.5372     Document Type: Article

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