Studies on the topology of the renal type II NaPi-cotransporter

Pflugers Archiv European Journal of Physiology

Volumn 437, Issue 6, 1999, Pages 972-978

  Lambert, G ^a   Traebert, M ^a   Hernando, N ^a   Biber, J ^a   Murer, H ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

FLAG; Phosphate; Sodium phosphate cotransport; Topology; Transport

Indexed keywords

ION TRANSPORT AFFECTING AGENT; SODIUM DIHYDROGEN PHOSPHATE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRUSH BORDER; CONTROLLED STUDY; EPITOPE MAPPING; IMMUNOPRECIPITATION; INTRACELLULAR TRANSPORT; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE ABSORPTION; MEMBRANE PERMEABILITY; MEMBRANE STRUCTURE; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; CARRIER PROTEINS; CELL LINE; DOGS; EPITOPES; FEMALE; GLYCOSYLATION; IMMUNOHISTOCHEMISTRY; IMMUNOSORBENT TECHNIQUES; KIDNEY TUBULES, PROXIMAL; MICROVILLI; MOLECULAR SEQUENCE DATA; OOCYTES; PEPTIDE FRAGMENTS; PEPTIDES; RATS; SODIUM-PHOSPHATE COTRANSPORTER PROTEINS; SODIUM-PHOSPHATE COTRANSPORTER PROTEINS, TYPE II; SYMPORTERS; TRANSFECTION; XENOPUS LAEVIS;

EID: 0032927673     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240050869     Document Type: Article

References (24)

1. 1. Beck L, Karaplis AC, Amizuka N, Hewson AS, Ozawa H, Tenenhouse HS (1998) Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities. Proc Natl Acad Sci USA 95:5372-5377
2. 2. Berndt TJ, Knox FG (1992) Renal regulation of phosphate excretion. In: Seldin DW, Giebisch G (eds) The kidney: physiology and pathophysiology. Raven, New York, pp 2511-2532
3. 3. Castrucci MR, Bilsel P, Kawaoka Y (1992) Attenuation of influenza A virus by insertion of a foreign epitope into the neuraminidase. J Virol 66:4647-4653
4. 4. Chang HC, Bush DR (1997) Topology of NAT2, a prototypical example of a new family of amino acid transporters. J Biol Chem 272:30552-30557
5. 5. Chraibi A, Vallet V, Firsov D, Hess SK, Horisberger JD (1998) Protease modulation of the activity of the epithelial sodium channel expressed in Xenopus oocytes. J Gen Physiol 111: 127-138
6. 2+ exchanger. Biochim Biophys Acta 1371:40-52
7. (i) cotransport in rat kidney: localization by RT-PCR and immunohistochemistry. Am J Physiol 266: F767-774
8. 8. Dennis VW (1992) Phosphate homeostasis. In: Windhager EE (ed) Renal physiology, vol. 2. Handbook of physiology series (section 8). American Physiological Society, Bethesda, Md., pp 1785-1815
9. 9. Firsov D, Schild L, Gautschi I, Merillat AM, Schneeberger E, Rossier BC (1996) Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approach. Proc Natl Acad Sci USA 93:15370-15375
10. 10. Hayes G, Busch A, Lotscher M, Waldegger S, Lang F, Verrey F, Biber J, Murer H (1994) Role of N-linked glycosylation in rat renal Na/Pi-cotransport. J Biol Chem 269:24143-24149
11. 11. Hofmann K, Stoffel W (1993) TMbase - a database of membrane spanning proteins segments. Biol Chem Hoppe-Seyler 347:166
12. 12. Jager H, Birkenhager R, Stalz WD, Altendorf K, Deckers-Hebestreit G (1998) Topology of subunit a of the Escherichia coli ATP synthase. Eur J Biochem 251:122-132
13. 13. Kast C, Gros P (1997) Topology mapping of the amino-terminal half of multidrug resistance-associated protein by epitope insertion and immunofluorescence. J Biol Chem 272: 26479-26487
14. 14. Kast C, Gros P (1998) Epitope insertion favors a six transmembrane domain model for the carboxy-terminal portion of the multidrug resistance-associated protein. Biochemistry 37: 2305-2313
15. 15. Magagnin S, Werner A, Markovich D, Sorribas V, Stange G, Biber J, Murer H (1993) Expression cloning of human and rat renal cortex Na/Pi cotransport. Proc Natl Acad Sci USA 90: 5979-5983
16. 16. Murer H, Biber J (1993) Structural identification of brush border membrane transport systems - towards an understanding of regulatory mechanisms. Clin Invest 71:852-854
17. 17. Murer H, Biber J (1994) Renal sodium-phosphate cotransport. Curr Opin Nephrol Hypertens 3:504-510
18. 18. Murer H, Biber J (1996) Molecular mechanisms of renal apical Na/phosphate cotransport. Annu Rev Physiol 58:607-618
19. 19. Murer H, Biber J (1997) A molecular view of proximal tubular inorganic phosphate (Pi) reabsorption and of its regulation. Pflügers Arch 433:379-389
20. +/Pi cotransporter by antisense oligonucleotides. Proc Natl Acad Sci USA 93: 4903-4906
21. 4 cotransporters in MDCK and LLC-PK1 cells by transfection. Am J Physiol 270:F220-228
22. 22. Sambrook J, Fritsch EF, Maniatis AM (1989) In: Nolan C (ed) Molecular cloning-a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
23. 23. Shih TM, Goldin AL (1997) Topology of the Shaker potassium channel probed with hydrophilic epitope insertions. J Cell Biol 136:1037-1045
24. 24. Werner A, Biber J, Forgo J, Palacin M, Murer H (1990) Expression of renal transport systems for inorganic phosphate and sulfate in Xenopus laevis oocytes. J Biol Chem 265: 12331-12336