Type II Na-P(i) cotransport is regulated transcriptionally by ambient bicarbonate/carbon dioxide tension in OK cells

American Journal of Physiology - Renal Physiology

Volumn 276, Issue 1 45-1, 1999, Pages

  Jehle, Andreas W ^a   Hilfiker, Helene ^a   Pfister, Markus F ^a   Biber, Jürg ^a   Lederer, Eleanor ^b   Krapf, Reto ^c   Murer, Heini ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b University of Louisville School of Medicine   (United States)

^c CANTONAL HOSPITAL ST GALLEN   (Switzerland)

Author keywords

Acidosis; Alkalosis; Parathyroid hormone; Promoter; Proximal tubule

Indexed keywords

BICARBONATE; CARBON DIOXIDE;

ACID BASE BALANCE; ANIMAL CELL; ARTICLE; CARBON DIOXIDE TENSION; HYPOPHOSPHATEMIA; KIDNEY PROXIMAL TUBULE; METABOLIC ACIDOSIS; NONHUMAN; OPOSSUM; PHOSPHATE METABOLISM; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

EID: 0032916306     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.1999.276.1.f46     Document Type: Article

References (31)

1. i cotransport in opossum kidney cells by extracellular phosphate. Am. J. Physiol. 255 (Cell Physiol. 24): C155-C161, 1988.
2. 4. Am. J. Physiol. 250 (Renal Fluid Electrolyte Physiol. 19): F827-F833, 1986.
3. i transport in cultured kidney cells. Am. J. Physiol. 257 (Renal Fluid Electrolyte Physiol. 26): F712-F717, 1989.
4. Caverzasio, J., R. Rizzoli, and J.-P. Bonjour. Sodium-dependent phosphate transport inhibited by parathyroid hormone and cyclic AMP stimulation in an opossum kidney cell line. J. Biol. Chem. 261: 3233-3237, 1986.
5. Emmett, M., S. Goldfarb, Z. S. Agus, and R. G. Narins. The pathophysiology of acid-base changes in chronically phosphatedepleted rats. J. Clin. Invest. 59: 291-298, 1977.
6. Forestal, D. A., J. Haimovici, and P. Haddad. Different effect of cold storage and rewarming on three pH regulating transporters in isolated rat hepatocytes. Am. J. Physiol. 272 (Gastrointest. Liver Physiol. 35): G638-G645, 1997.
7. Harrold, S., C. Genovese, B. Korbin, S. L. Morrison, and C. Milcarek. A comparison of the apparent mRNA half-life using kinetic labeling techniques vs. decay following administration of transcriptional inhibitors. Anal. Biochem. 198: 19-29, 1991.
8. i cotransporter gene. Am. J. Physiol. 274 (Renal Fluid Electrolyte Physiol. 43): F197-F204, 1998.
9. Houillier, P., P. Borensztein, M. Bichara, M. Paillard, and A. Prigent. Chronic neutral phosphate supplementation induces sustained renal metabolic alkalosis. Kidney Int. 41: 1182-1191, 1992.
10. i cotransport in OK cells: molecular characterization and effect of dexamethasone. Am. J. Physiol. 273 (Renal Physiol. 42): F396-F403, 1997.
11. Jentsch, T. J., P. Schwartz, B. S. Schill, B. Langner, A. P. Lepple, S. K. Keller, and M. Wiederholt. Kinetic properties of the sodium bicarbonate (carbonate) symport in monkey kidney epithelial cells (BSC-1). J. Biol. Chem. 261: 10673-10679, 1986.
12. Knochel, J. P. The clinical and physiological implications of phosphorus deficiency. In: The Kidney: Physiology and Pathophysiology (2nd ed.) edited by D. W. Seldin and G. Giebisch. New York: Raven 1992, p. 2533-2562.
13. Koyama, H., C. Goodpasture, M. M. Miller, R. L. Teplitz, and A. D. Riggs. Establishment and characterization of a cell line from the American opossum (Didelphis virginiana). In Vitro (Rockville) 14: 239-246, 1978.
14. Krapf, R., C. B. Berry, R. J. Alpern, and F. C. Rector. Regulation of cell pH by ambient bicarbonate, carbon dioxide tension, and pH in the rabbit proximal convoluted tubule. J. Clin. Invest. 81: 381-389, 1988.
15. Krapf, R., M. Glatz, and H. N. Hulter. Neutral phosphate administration generates and maintains renal metabolic alkalosis and hyperparathyroidism. Am. J. Physiol. 268 (Renal Fluid Electrolyte Physiol. 37): F802-F807, 1995.
16. Krapf, R., P. Jaeger, and H. N. Hulter. Chronic respiratory alkalosis induces renal PTH-resistance, hyperphosphatemia and hypocalcemia in humans. Kidney Int. 42: 727-734, 1992.
17. Krapf, R., R. Vetsch, W. Vetsch, and H. N. Hulter. Chronic metabolic acidosis increases the serum concentration of 1,25-dihydroxyvitamin D in humans by stimulating its production rate. J. Clin. Invest. 90: 2456-2463, 1992.
18. Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970.
19. 3 cells. Am. J. Physiol. 251 (Cell Physiol. 20): C23-C31, 1986.
20. Mostellar, M. E., and E. P. Tuttle. Effects of alkalosis on plasma concentration and urinary excretion of inorganic phosphate in man. J. Clin. Invest. 43: 138-149, 1964.
21. i) reabsorption and its regulation. Pflügers Arch. 433: 379-389, 1997.
22. i-cotransporters. J. Biol. Chem. 272: 20125-20130, 1997.
23. Reshkin, S. J., J. Forgo, J. Biber, and H. Murer. Functional asymmetry of phosphate transport and its regulation in opossum kidney cells: phosphate "adaptation." Pflügers Arch. 419: 256-262, 1991.
24. Reshkin, S. J., J. Forgo, and H. Murer. Functional asymmetry of phosphate transport and its regulation in OK-cells: phosphate transport. Pflügers Arch. 416: 554-560, 1990.
25. Sorribas, V., D. Markovich, G. Hayes, G. Stange, J. Forgo, J. Biber, and H. Murer. Cloning of a Na/Pi-cotransporter from opossum kidney cells. J. Biol. Chem. 269: 6615-6621, 1994.
26. Struyenberg, A., R. B. Morrison, and A. S. Relman. Acid-base behavior of separated canine renal tubule cells. Am. J. Physiol. 214: 1155-1162, 1968.
27. Towbin, H., T. Staehelin, and J. Gordon. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76: 4350-4354, 1979.
28. Tso, J. Y., X. H. Sun, T. H. Kao, K. S. Reece, and R. Wu. Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNA: genomic complexity and molecular evolution of the gene. Nucleic Acids Res. 13: 2485-2502, 1985.
29. Vrtovsnik, F., M. Jourdain, G. Cherqui, J. Lefebvre, and G. Friedlander. Glucocorticoid inhibition of Na/Pi-cotransport in renal epithelial cells is mediated by protein kinase C. J. Biol. Chem. 269: 8872-8877, 1994.
30. Webb, R. K., P. B. Woodhall, C. C. Tisher, G. Glaubiger, F. A. Neelon, and F. A. Robinson. Relationship between phosphaturia and acute hypercapnia in the rat. J. Clin. Invest. 60: 829-837, 1977.
31. Zilenovski, A. M., S. Kuroda, S. Bhat, D. E. Band, and N. Bank. Effect of sodium bicarbonate on phosphate excretion in acute and chronic PTX rats. Am. J. Physiol. 236 (Renal Fluid Electrolyte Physiol. 5): F184-F191, 1979.