메뉴 건너뛰기




Volumn 166, Issue 1, 2000, Pages 115-126

Partial functional recovery of paraplegic rat by adenovirus-mediated gene delivery of constitutively active MEK1

Author keywords

Adenovirus; Gene therapy; MEK; Spinal cord injury

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; VIRUS VECTOR;

EID: 0033757086     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.2000.7493     Document Type: Article
Times cited : (31)

References (50)
  • 3
    • 0030763998 scopus 로고    scopus 로고
    • Targeted transduction of CNS neurons with adenoviral vectors carrying neurotrophic factor genes confers neuroprotection that exceeds the transduced population
    • (1997) J. Neurosci. , vol.17 , pp. 6504-6511
    • Baumgartner, B.J.1    Shine, H.D.2
  • 4
    • 0032534698 scopus 로고    scopus 로고
    • Permanent rescue of lesioned neonatal motoneurons and enhanced axonal regeneration by adenovirus-mediated expression of glial cell-line-derived neurotrophic factor
    • (1998) J. Neurosci. Res. , vol.54 , pp. 766-777
    • Baumgartner, B.J.1    Shine, H.D.2
  • 7
    • 0029840835 scopus 로고    scopus 로고
    • Spinal cord repair in adult paraplegic rats: Partial restoration of hind limb function
    • (1996) Science , vol.273 , pp. 510-513
    • Cheng, H.1    Cao, Y.2    Olson, L.3
  • 14
    • 0026531499 scopus 로고
    • Ciliary neurotrophic factor prevents neuronal degeneration and promotes low affinity NGF receptor expression in the adult rat CNS
    • (1992) Neuron , vol.8 , pp. 145-158
    • Hagg, T.1    Quon, D.2    Higaki, J.3    Varon, S.4
  • 20
    • 0023067115 scopus 로고
    • Nerve growth factor treatment after brain injury prevents neuronal death
    • (1987) Science , vol.235 , pp. 214-216
    • Kromer, L.F.1
  • 26
    • 0023684176 scopus 로고
    • Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons
    • (1988) J. Neurosci. , vol.8 , pp. 2394-2405
    • Lindsay, R.M.1
  • 31
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 32
    • 0017853307 scopus 로고
    • Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: A noncarcinogenic blue reaction product with superior sensitivity for visualizing neural afferents and efferents
    • (1978) J. Histochem. Cytochem. , vol.26 , pp. 106-117
    • Mesulam, M.M.1
  • 35
    • 0031451444 scopus 로고
    • Regeneration in the adult central nervous system: Experimental repair strategies
    • (1993) Nature Med , vol.3 , pp. 1329-1335
    • Olson, L.1
  • 38
    • 0024245612 scopus 로고
    • Characterization of insulin-stimulated microtubule-associated protein kinase. Rapid isolation and stabilization of a novel serine/threonine kinase from 3T3-L1 cells
    • (1988) J. Biol. Chem. , vol.263 , pp. 12721-12727
    • Ray, L.B.1    Sturgill, T.W.2
  • 49
    • 0028963084 scopus 로고
    • Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor
    • (1995) Science , vol.267 , pp. 2003-2006
    • Yao, R.1    Cooper, G.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.